Mugadziri weupfu hweAmino Tadalafil Nhamba yeCAS: 385769-84-6 98% kuchena kweminiti yezvinongedzo zvekuwedzera
Vhidhiyo yeChigadzirwa
Zvimiro zveChigadzirwa
| Zita rechigadzirwa | Amino Tadalafil |
| Rimwe zita | (6R,12aR)-2-Amino-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione;AminoTadalafil(6R,12Ar)-2-Amino-6-(1,3-Benzodioxol-5-Yl)-2,3,6,7,12,12A-Hexahydropyrazino[1',2':1,6]Pyrido[3,4-B]Indole-1,4-Dion e;(6R,12aR)-2-Amino-6-(benzo[d][1,3]dioxol-5-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indol-1,4-dione;(6R,12aR)-2-amino-6-(benzo[d][1,3]dioxol-5-yl)-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione |
| Nhamba yeCAS | 385769-84-6 |
| Fomura yemamorekuru | C21H18N4O4 |
| Kurema kwemasero | 390.39 |
| Kuchena | 98.0% |
| Chitarisiko | Upfu huchena kusvika huchena |
| Kushandiswa | Zvekudya Zvinowedzerwa Zvekudya Zvakagadzirwa |
Sumo yechigadzirwa
Amino Tadalafil chinhu chitsva, chinobva mu tadalafil, chiri kuramba chichifarirwa munyaya dzekushaya simba kwepabonde (ED). Chinosanganisa amino acid ne tadalafil, chinhu chinodzivirira PDE5 chakatenderwa neFDA chinoshandiswa kurapa ED. Chinoshanda nekuwedzera kuyerera kweropa kuenda kunhengo yemurume, zvichibvumira varume kuti vagone kugara zvakanaka. Amino acids, kune rumwe rutivi, inoita basa rakakosha mumabasa akasiyana-siyana emuviri, kusanganisira kugadzirwa kwemapuroteni, ayo ari maburi enyama nenhengo. Kusanganiswa kwezvinhu zviviri izvi kwakagadzirirwa kuwedzera kushanda kweTadalafil mukurapa ED. Uye amino Tadalafil imhando yakagadziridzwa ine simba rinoshamisa, ichivandudza mashandiro uye kushanduka-shanduka kweyakaitangira. Maumbirwo ayo emakemikari anoramba akafanana neTadalafil, asi kuburikidza nekuunzwa kwemaamino groups, inowana hunhu hwakasiyana hunoita kuti ive yakasiyana munyika yemishonga. Kufanana ne tadalafil, Amino Tadalafil inoshanda nekudzivisa phosphodiesterase 5 (PDE5), enzyme inokonzera kuputsa cyclic guanosine monophosphate (cGMP) mumuviri. cGMP chinhu chechisikigo chinokurudzira kugadzikana kwetsinga dzeropa, nokudaro zvichiwedzera kuyerera kweropa. Nekudzivisa PDE5, amino Tadalafil inoita kuti cGMP iungane, nokudaro ichisimudzira kuyerera kweropa uye inovandudza kutenderera kweropa. Pamusoro pezvo, vaongorori vakaongorora kugona kwayo kubatsira kurapa benign prostatic hyperplasia (BPH) nekusimudzira kuyerera kweropa kuprostate.
Chinhu
(1) Kuchena kwakanyanya: Amino Tadalafil inogona kuwana zvigadzirwa zvakachena zvakanyanya kuburikidza nekugadzira kwakanatswa. Kuchena kwakanyanya kunoreva kuwanikwa kuri nani kwemuviri uye kushomeka kwemhedzisiro yakaipa.
(2) Kuchengetedzwa: Kuchengetedzwa kwakanyanya, kusawirirana kushoma.
(3) Kugadzikana: Amino Tadalafil ine kugadzikana kwakanaka uye inogona kuchengetedza kushanda kwayo pasi pemamiriro akasiyana-siyana uye mamiriro ekuchengetedza.
Mashandisirwo
Amino Tadalafil inhibitor yePDE5 ine mhedzisiro yakafanana neye tadalafil. Nekubatanidza maamino acids netadalafil, amino Tadalafil inofungidzirwa kuti inoshanda zvakanyanya mukurapa kusagadzikana kwepabonde kupfuura tadalafil chete. Maamino acids anogona kubatsira kusimudzira kutenderera kweropa uye kutsigira kushanda kwemishonga. Pamusoro pezvo, inogona kuvandudza zviratidzo zvekutadza kushanda kwepabonde (ED) nekudzivirira kushanda kwePDE5 enzyme kukurudzira kuyerera kweropa munhengo dzekubereka dzevarume. Kana ichienzaniswa netadalafil, amino Tadalafil inogayiwa zvishoma nezvishoma mumuviri uye inogona kugadzira mhedzisiro inogara kwenguva refu. Izvi zvinopa amino Tadalafil mukana mukuru mukurapa ED.
