Mugadziri weupfu weNefiracetam Nhamba yeCAS: 77191-36-7 99% kuchena kweminiti yezvinongedzo zvekuwedzera
Vhidhiyo yeChigadzirwa
Zvimiro zveChigadzirwa
| Zita rechigadzirwa | Nefiracetam |
| Rimwe zita | n-(2,6-dimethylphenyl)-2-oxo-1-pyrrolidineacetamide;NEFIRACETAM; 2-oxo-1-pyrrolidinylaceticacid, 2,6-dimethylanilide; dm9384; n-(2,6-dimethylphenyl)-2-oxo-1-pyrrolidineacetamid;DM-9384,(2-(2-Oxopyrrolidin-1-yl)-N-(2,6-dimethylphenyl)-acetamide); DMPA |
| Nhamba yeCAS | 77191-36-7 |
| Fomura yemamorekuru | C14H18N2O2 |
| Kurema kwemasero | 246.3 |
| Kuchena | 99.0% |
| Chitarisiko | Upfu chena |
| Kurongedza | 25 kg/bhareri |
| Kushandiswa | nootropic |
Sumo yechigadzirwa
Nefiracetam ndeyemhuri yepiracetam, boka remishonga inozivikanwa nehunyanzvi hwayo hwekuvandudza kugona kwemunhu. Nefiracetam yakatanga kugadzirwa kutanga kwema1980 uye yakakurumidza kukwezva kutariswa nekuda kwemaitiro ayo akasiyana ekushanda uye mashandisirwo ayo ekurapa. Iyi racemic compound inofungidzirwa kuti inokanganisa ma neurotransmitters nema receptors muuropi, zvichizosimudzira kugona kwekuziva kuri nani. Nefiracetam inonyanya kukanganisa huwandu hweuropi hweacetylcholine, neurotransmitter yakakosha inotarisira kurangarira, kudzidza, uye kushanda kwekuziva. Nekugadzirisa ma acetylcholine receptors, nefiracetam inokurudzira kutaurirana kwakawedzerwa pakati pema neuron, nokudaro ichivandudza synaptic plasticity uye inovandudza kuchengetedza ndangariro. Pamusoro pezvo, nefiracetam inosangana nema gamma-aminobutyric acid (GABA) receptors kubatsira kudzikamisa mamiriro e neurotransmitter. Nekubatsira zvakanaka ma neurotransmitters anokurudzira uye anodzivirira, nefiracetam inobatsira kuchengetedza kushanda kwehuropi kwakaringana, nokudaro ichivandudza kutarisa, kutarisisa, uye kushanda kwehuropi kwese.
Chinhu
(1) Kuchena kwakanyanya: Nefiracetam inogona kuwana zvigadzirwa zvakachena zvakanyanya kuburikidza nekugadzira kwakanatswa. Kuchena kwakanyanya kunoreva kuwanikwa kuri nani kwemuviri uye kushomeka kwemigumisiro yakaipa.
(2) Kuchengetedzeka: Kuchengeteka kwakanyanya, kusawirirana kushoma.
(3) Kugadzikana: Nefiracetam ine kugadzikana kwakanaka uye inogona kuchengetedza kushanda kwayo uye kushanda kwayo munzvimbo dzakasiyana uye mamiriro ekuchengetedza.
Mashandisirwo
Nefiracetam chinhu chinobva mupiracetam chinobvisa calcium mumuviri, icho chinowanzoonekwa sechinhu chinokonzera kuwanikwa kwecalcium channels mumuviri uye kutamiswa kwakananga kwezvinhu zvinosimudzira kuratidzwa kwesimba sechikamu che calcium ion channels. Glycine binding site yeNDMA receptor. Kuburikidza nemhedzisiro yayo pa cerebral cortex, nefiracetam inogona kuwedzera kugona kwekuziva uye kudzivirira kudzikira kwekudzidza nekurangarira. Haina muscarinic receptor agonist kana antagonist properties, uye haidzivisi acetylcholinease activity. Nokudaro, mhedzisiro yayo yekurwisa amnestic uye yekuvandudza ndangariro inowanikwa nekuvandudza kuburitswa kweacetylcholine mucerebral cortex.
