Mugadziri weupfu hweN-Boc-O-Benzyl-D-serine Nhamba yeCAS:47173-80-8 98% kuchena kweminiti yepakati
Zvimiro zveChigadzirwa
| Zita rechigadzirwa | N-Boc-O-Benzyl-D-serine |
| Rimwe zita | N-Boc-O-benzyl-D-serine; Boc-O-benzyl-D-serine; O-Benzyl-N-(tert-butoxycarbonyl)-D-serine; Boc-(R)-2-amino-3-benzyloxypropionic acid; Boc-D-Ser(Bzl)-OH;Nat.-Boc-O-benzyl-D-serine; N-tert-butyloxycarbonyl-O-benzyl-D-serine; Nalpha-t-butoxycarbonyl-O-benzyl-D-serine; |
| Nhamba yeCAS | 47173-80-8 |
| Fomura yemamorekuru | C15H21NO5 |
| Kurema kwemasero | 295.33 |
| Kuchena | 98% |
| Kurongedza | 1kg/bhegi; 25kg/dhiramu |
| Kushandiswa | Vari pakati |
Sumo yechigadzirwa
N-Boc-O-Benzyl-D-serine chinhu chakanyanya kutariswa munyaya dzemakemikari echisikigo uye tsvakurudzo yemishonga. Chinhu ichi, chinozivikanwawo seBoc-D-serine, chinobva muamino acid D-serine uye chinoshandiswa zvakanyanya mukugadzirwa kwemishonga yakasiyana-siyana uye mamorekuru anoshanda. N-Boc-O-Benzyl-D-serine ipfu yekristalline chena kusvika kuchena isinganyungudike zvakanyanya mumvura uye inonyungudika muzvinhu zvinonyungudika zvakaita semethanol neethanol. Chinhu chinobva kuD-serine, inova amino acid isiri proteinogenic inoita basa rakakosha muhurongwa hwetsinga semubatsiri weN-methyl-D-aspartate (NMDA) receptor. Mapoka eN-Boc (tert-butoxycarbonyl) neO-Benzyl ari mukombuta anoshanda semapoka anodzivirira, zvichibvumira kushandiswa kweamino acid panguva yekugadzira makemikari. N-Boc-O-Benzyl-D-serine inonyanya kushandiswa sechivako mukugadzirwa kwemapeptide nemapeptidomimetics. Mapeptides macheni mapfupi emaamino acids anoita mabasa akasiyana-siyana mumaitiro ehupenyu uye anofarira zvikuru kuwanikwa kwemishonga nekugadzirwa kwayo. Nekubatanidza N-Boc-O-Benzyl-D-serine muzvikamu zvepeptide, masayendisiti emakemikari anogona kugadzirisa hunhu nemabasa emapeptides anobuda, zvichiita kuti ive chishandiso chakakosha mukugadzirwa kwemishonga mitsva. Uyezve, N-Boc-O-Benzyl-D-serine inoshandiswa mukugadzirira mishonga yemishonga uye zvinhu zvinoshanda zvemishonga (APIs). Kushanda kwayo kwakasiyana-siyana uye kuenderana kwayo nemaitiro akasiyana-siyana emakemikari kunoita kuti ive chikamu chinodiwa mukugadzirwa kwemamorekuru akaomarara ane mukana wekurapa.
Chinhu
(1) Kuchena kwakanyanya: N-Boc-O-Benzyl-D-serine inogona kuwana zvigadzirwa zvine kuchena kwakanyanya kuburikidza nemaitiro ekugadzira akacheneswa. Kuchena kwakanyanya kunoreva kuwanikwa kuri nani kwehupenyu uye kushomeka kwemhedzisiro yakaipa.
(2) Kuchengetedzeka: Kuchengeteka kwakanyanya, kusawirirana kushoma.
(3) Kugadzikana: N-Boc-O-Benzyl-D-serine ine kugadzikana kwakanaka uye inogona kuchengetedza kushanda kwayo uye kushanda kwayo pasi pemamiriro akasiyana-siyana uye mamiriro ekuchengetedza.
Mashandisirwo
Kuiswa kweN-Boc-O-Benzyl-D-serine mumamorekuru emishonga kwakaratidzwa kuti kunopa hunhu hunodiwa hwe pharmacokinetic uye pharmacodynamic. Peptidomimetics inobva kuN-Boc-O-Benzyl-D-serine yakaratidza kugadzikana kwakawedzerwa, kuwanikwa kwehupenyu, uye hunyanzvi hwechinangwa, zvichiita kuti ive mishonga inobudirira yekurapa zvirwere zvakasiyana-siyana, zvinosanganisira kenza, zvirwere zvinotapukira, uye zvirwere zvetsinga. Uyezve, kugona kugadzirisa N-Boc-O-Benzyl-D-serine nenzira yakasarudzika kunobvumira kugadziriswa kwemishonga, nekuvandudza mashandiro ayo uye kuchengetedzeka.
