1,4-DihydronicotinaMide Riboside powder inogadzira Nhamba yeCAS:19132-12-8 98% kuchena kweminiti yezvinongedzo zvekuwedzera
Zvimiro zveChigadzirwa
| Zita rechigadzirwa | 1,4-DihydronicotinaMide Riboside |
| Rimwe zita | 1,4-DIHYDRONICOTINAMIDE RIBOSIDE1-[(3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,4-dihydropyridine-3-carboxamideSCHEMBL188493711-[(3R,4S,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-4H-PYRIDINE-3-CARBOXAMIDE |
| Nhamba yeCAS | 19132-12-8 |
| Fomura yemamorekuru | C11H16N2O5 |
| Kurema kwemasero | 256.26 |
| Kuchena | 98% |
| Chitarisiko | Upfu chena |
| Kurongedza | 1kg/bhegi; 25kg/dhiramu |
| Kushandiswa | Zvekudya zvinovaka muviri |
Sumo yechigadzirwa
1,4-dihydronicotinamide riboside, inozivikanwawo seNRH.Rudzi rwakaderedzwa rweNRH chinhu chine simba cheNAD+ chinobatsira kuzadza huwandu hwayo musero.
Chekutanga uye chakakosha, zvakakosha kunzwisisa basa reNAD+ mumuviri. NAD+ ikemikari inoshanda mumabasa akawanda emasero, kusanganisira kushandiswa kwesimba, kugadzirisa DNA, uye kugadzirwa kwemajini. Sezvatinokura, huwandu hwedu hweNAD+ hunoderera, izvo zvave zvichibatanidzwa mukukwegura uye zvirwere zvine chekuita nekukwegura. Izvi zvakaita kuti pave nekufarira kukuru mukuziva mamorekuru anogona kuwedzera huwandu hweNAD+ mumuviri, uye 1,4-dihydronicotinamide riboside imwe yemamorekuru akadaro.
1,4-dihydronicotinamide riboside chinhu chinobatsira pakurapa chirwere cheNAD+, uye tsvakurudzo yakaratidza kuti inogona kusimudzira mazinga eNAD+ mumasero. Izvi zvakaita kuti pave nefungidziro yekuti kuwedzera kwe1,4-dihydronicotinamide riboside kunogona kuva nemhedzisiro yekurapa muzvirwere zvakasiyana-siyana, kusanganisira matambudziko ekugaya chikafu, zvirwere zvinokanganisa mashandiro etsinga, uye kudzikira kunokonzerwa nekukwegura.
Kutaura zvazviri, pane humbowo hunoratidza kuti 1,4-dihydronicotinamide riboside inogona kushanda zvakanyanya kupfuura molekyuru yayo huru, nicotinamide riboside, pakuwedzera mazinga eNAD+. Izvi zvinodaro nekuti 1,4-dihydronicotinamide riboside inoderedza simba, zvichireva kuti iri nani pakupa maerekitironi munzira yekugadzira NAD+. Nekuda kweizvozvo, ine mukana wekupa simba rakawanda kugadzirwa kweNAD+ mumasero.
Pamusoro pebasa rayo muNAD+ biosynthesis, 1,4-dihydronicotinamide riboside inewo hunhu hweantioxidant. Kushushikana kwe oxidative, kunokonzerwa nekusawirirana pakati pefree radicals nema antioxidants mumuviri, kunobatanidzwa muzvirwere zvakawanda, zvinosanganisira kenza, chirwere chemwoyo, uye zvirwere zve neurodegenerative. Nekubvisa free radicals uye kuderedza kukuvara kwe oxidative, 1,4-dihydronicotinamide riboside inogona kupa mamwe mabhenefiti ehutano kupfuura basa rayo seNAD+ precursor.
Chinhu
(1) Kuchena kwakanyanya: 1,4-dihydronicotinamide riboside inogona kuwana zvigadzirwa zvine kuchena kwakanyanya kuburikidza nemaitiro ekugadzira akacheneswa. Kuchena kwakanyanya kunoreva kuwanikwa kuri nani kwehupenyu uye kushomeka kwemhedzisiro yakaipa.
(2) Kuchengeteka: 1,4-dihydronicotinamide riboside chigadzirwa chechisikigo chakaratidza kuti chakachengeteka mumuviri wemunhu.
(3) Kugadzikana: 1,4-dihydronicotinamide riboside ine kugadzikana kwakanaka uye inogona kuchengetedza kushanda kwayo uye kushanda kwayo pasi pemamiriro akasiyana-siyana uye mamiriro ekuchengetedza.
Mashandisirwo
1,4-Dihydronicotinamide ndiyo mhando yakaderera ye nicotinamide riboside. Inogona kuvapo mumhando dzakasanganiswa nedzakaderedzwa uye ndiyo nzira yekutanga kune NAD ichangobva kuwanikwa (nicotinamide adenine dinucleotide), inowanikwa sekuwedzera, NRH iri iyo inotangira NAD+ ine simba uye inokurumidza kupfuura NR.
