7,8-Dihydroxyflavone (7,8-DHF) mugadziri weupfu Nhamba yeCAS: 38183-03-8 98.0% kuchena kweminiti yezvinongedzo zvekuwedzera

Tsananguro pfupi:

7,8-Dihydroxyflavone, inozivikanwawo se7,8-DHF, iflavonoid inowanikwa mumiti yakasiyana-siyana, kusanganisira Tridacna tridacna. Ichizivikanwa nemasimba ayo ekudzivirira muviri uye neurotrophic, chimwe chezvinhu zvinonakidza zve7,8-dihydroxyflavone kugona kwayo kutsigira hutano hwehuropi nekuvandudza mashandiro epfungwa.

Tumira email kwatiri

Ruzivo rweChigadzirwa

Matagi eChigadzirwa

Vhidhiyo yeChigadzirwa

Zvimiro zveChigadzirwa

Zita rechigadzirwa	7,8-Dihydroxyflavone
Rimwe zita	7,8-DIHYDROXYFLAVONE; 7,8-dihydroxy-2-phenyl-4-benzopyrone; DIHYDROXYFLAVONE, 7,8-(RG); 7,8-Dihydroxyflavone hydrate; 7,8-dihydroxy-2-phenyl-1-benzopyran-4-imwe
Nhamba yeCAS	38183-03-8
Fomura yemamorekuru	C15H10O4
Kurema kwemasero	254.24
Kuchena	98.0%
Chitarisiko	Upfu hweyero
Kushandiswa	Zvekudya Zvinowedzerwa Zvekudya Zvakagadzirwa

Sumo yechigadzirwa

7,8-Dihydroxyflavone, inozivikanwawo se7,8-DHF, iflavonoid inowanikwa mumiti yakasiyana-siyana, kusanganisira Tridacna tridacna. Inozivikanwa nemasimba ayo ekudzivirira muviri uye neurotrophic, chimwe chezvinhu zvinonakidza zve7,8-dihydroxyflavone kugona kwayo kutsigira hutano hwehuropi nekuvandudza mashandiro epfungwa. Tsvagiridzo inoratidza kuti iyi compound inoshanda se neurotrophin ine simba, ichikurudzira kukura uye kupona kwema neuron muuropi. Zvidzidzo mumhuka dzemurabhoritari zvakaratidza kuti 7,8-DHF inovandudza zvakanyanya kugona kwekurangarira nekudzidza. Nekukurudzira kuumbwa kwekubatana kutsva kwe synaptic uye kusimudzira kutaurirana pakati pemasero ehuropi, iyi compound inovimbisa kuvhura kugona kwedu kwekuziva. Pamusoro pezvo, 7,8-dihydroxyflavone inosangana nema serotonin receptors europi, ayo anobatanidzwa mukudzora mafungiro. Nekugadzirisa ma receptors aya, inogona kukwanisa kuderedza zviratidzo zvekushushikana nekuora mwoyo.

Chinhu

(1) Kuchena kwakanyanya: 7,8-Dihydroxyflavone inogona kuwana zvigadzirwa zvakachena zvakanyanya kuburikidza nekubviswa kwechisikigo uye maitiro ekugadzira zvinyoro nyoro. Kuchena kwakanyanya kunoreva kuwanikwa kuri nani kwehupenyu uye kushomeka kwemhedzisiro yakaipa.

(2) Kuchengetedzwa: 7,8-Dihydroxyflavone chigadzirwa chechisikigo chakaratidzwa kuti chakachengeteka kuvanhu. Mukati mehuwandu hwemushonga, haina chepfu kana migumisiro yakaipa.

(3) Kugadzikana: 7,8-Dihydroxyflavone ine kugadzikana kwakanaka uye inogona kuchengetedza kushanda kwayo uye kushanda kwayo mumamiriro akasiyana ezvakatipoteredza uye ekuchengetera.

(4) Zviri nyore kunyudza: 7,8-Dihydroxyflavone inogona kunyudzwa nekukurumidza nemuviri wemunhu, kupinda muropa kuburikidza nedumbu, uye kupararira kune nhengo dzakasiyana dzemuviri.

Mashandisirwo

7, 8-DHF, semushonga unoshanda weTrkB receptor, inogona kuita basa rekudzivirira neuron, kugadzurwa kweneuron, kudzorwa kwesynaptic plasticity, nezvimwewo nekuita kuti BDNF ibatane neTrkB uye kuita kuti zviratidzo zve downstream signal pathways zviwedzere, kuitira kuti zviratidzo zvekudzidza kwemanzwiro zviwedzere uye kudzikira kwendangariro, kudzikira kwekuziva, kudzikira kwekushanda kwemuviri nezvimwe zviratidzo zvechirwere chetsinga senge chirwere cheAlzheimer kana mhando dzemhuka dzinokura, uye kuderedza mamiriro ezvinhu ane chekuita nechirwere chepfungwa nemhuka dzakafuta. Panguva iyi, kusvika pari zvino, hapana migumisiro ine chepfu ye7,8-DHF yakawanikwa mumhuka dzinoyedzwa. 7,8-DHF ine mukana mukuru uye kukosha mukudzivirira nekurapa matambudziko ane chekuita neBDNF/TrkB.