Beta-Nicotinamide Adenine Dinucleotide(NAD+) mugadziri weupfu Nhamba yeCAS: 53-84-9 98.5% kuchena kweminiti yezvinongedzo zvekuwedzera

Tsananguro pfupi:

NAD+, kana kuti nicotinamide adenine dinucleotide, ienzyme inowanikwa mumasero ese mapenyu. Inoita basa rakakosha mukushandiswa kwemasero, kunyanya mukuita kwe redox, izvo zvinosanganisira kutamiswa kwemaerekitironi pakati pemamorekuru. NAD+ inobatanidzwa mukuita kwe anabolic ne catabolic, zvichiita kuti ive chinhu chakakosha mukushandiswa kwesimba.

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Ruzivo rweChigadzirwa

Matagi eChigadzirwa

Zvimiro zveChigadzirwa

Zita rechigadzirwa	Nicotinamide Mononucleotide
Rimwe zita	NICOTINAMIDE RIBOTIDE; BETA-Nicotinamide Mononucleotide； Ribonucleotide yeNicotinaMide; β-Nicotinamide Mononucleotide ()
Nhamba yeCAS	1094-61-7
Fomura yemamorekuru	C11H15N2O8P
Kurema kwemasero	334.22
Kuchena	98.0%
Chitarisiko	Upfu chena
Kurongedza	1kg/bhegi 10kg/dhiramu
Kushandiswa	Kurwisa Kukwegura

Sumo yechigadzirwa

Beta-Nicotinamide Adenine Dinucleotide (Beta-NAD+), inozivikanwa seBeta-NAD, imorekuru inokosha inowanikwa mumasero ese mapenyu. Inoita basa rakakosha mumabasa akasiyana-siyana ehupenyu, kusanganisira metabolism yesimba uye signaling yemasero. Beta-Nicotinamide Adenine Dinucleotide inogadzirwa kubva ku niacin (vhitamini B3) neATP (adenosine triphosphate) kuburikidza nemaitiro akasiyana-siyana e enzyme. Munguva yekufema kwemasero, Beta-Nicotinamide Adenine Dinucleotide i coenzyme inobatsira kutamiswa kwemaerekitironi panguva yekuputsika kweglucose nemamwe ma biomolecules. Kutamiswa kwemaerekitironi uku kwakakosha pakugadzira ATP, mari yesimba yesero. Pasina Beta-Nicotinamide Adenine Dinucleotide, masero haagone kugadzira simba zvinobudirira uye kuita mabasa awo akakosha. Kuwedzera kune basa rayo mu metabolism yesimba, Beta-Nicotinamide Adenine Dinucleotide inoshanda se substrate yema enzyme akasiyana-siyana anobatanidzwa mukutumira maerekitironi uye kutonga kwemasero. Rimwe boka rinozivikanwa rema enzyme anoshandisa Beta-Nicotinamide Adenine Dinucleotide iSirtuins, ayo anobatanidzwa mumabasa akasiyana-siyana emasero, anosanganisira kugadzirisa DNA, kugadzirwa kwemajini, uye kukwegura. Ma enzyme aya anoda Beta-Nicotinamide Adenine Dinucleotide sechikamu che cofactor kuti aite basa rawo re enzyme.

Chinhu

(1) Kuchena kwakanyanya: NAD+ inogona kuwana zvigadzirwa zvakachena zvakanyanya kuburikidza nekugadzira zvinhu zvakachena. Kuchena kwakanyanya kunoreva kuwanikwa kuri nani kwehupenyu uye kusaita zvinhu zvakaipa.

(2) Kuchengetedzeka: Kuchengeteka kwakanyanya, kusawirirana kushoma.

(3) Kugadzikana: NAD+ ine kugadzikana kwakanaka uye inogona kuchengetedza kushanda kwayo uye kushanda kwayo pasi penzvimbo dzakasiyana uye mamiriro ekuchengetedza.

Mashandisirwo

NAD+ ikemikari inoshanda zvakanyanya mumabasa akasiyana-siyana ehupenyu, kusanganisira kushandiswa kwesimba, kugadzirisa DNA, uye kuratidza masero. NAD+ inobatanidzwawo mune mamwe maitiro emasero akadai sekugadzirisa DNA, kuratidzwa kwemajini, uye kuratidza calcium. Zvakakosha kuti munhu arambe achikura zvakanaka, sezvo mazinga eNAD+ achiderera nekukura, zvichikonzera kudzikira kwekushandiswa kwemasero uye kuwedzera kukuvara kwemasero. Mazinga eNAD+ anoderera nekukura, uye kudzikira uku kunobatanidzwa nezvirwere zvine chekuita nekukwegura. Kuwedzera neNAD+ precursors kwakaratidzwa kuwedzera mazinga eNAD+ uye kune mhedzisiro yakanaka yekukwegura.