Oleoylethanolamide (OEA) mugadziri wehupfu CAS Nhamba: 111-58-0 98%, 85% kuchena min. zvekuwedzera zvinhu
Product Parameters
| Product name | Oleoyl ethanolamide |
| Rimwe zita | N-oleoyl ethanolamine; N-(2-hydroxyethyl)-,(Z) -9-Octadecenamide |
| CAS Nha. | 111-58-0 |
| Molecular formula | C20H39NO2 |
| Molecular uremu | 325.53 |
| Kuchena | 98.0%, 85.0% |
| Chitarisiko | Fine white crystal powder |
| Packing | 1kg / bhegi, 25kg / ngoma |
| Application | Kubvisa marwadzo, anti-inflammatory |
Product sumo
Oleoylethanolamide chikamu chechipiri amide chinoumbwa ne lipophilic oleic acid uye hydrophilic ethanolamine. Oleoylethanolamide zvakare inongoitika lipid molecule mune dzimwe mhuka uye chirimwa tishu. Inowanikwa zvakanyanya mumhuka nezvirimwa zvinyama zvakaita secocoa poda, soya beans, uye nzungu, asi zvirimo zvakaderera zvakanyanya. Chete kana nharaunda yekunze yachinja kana chikafu chikakurudzirwa, matishu emasero emuviri Ipapo ndipo paizogadzirwa zvakawanda zvechinhu ichi.
Patembiricha yemumba, Oleoylethanolamide igobvu chena ine nzvimbo yekunyungudika ingangoita 50°C. Inonyungudika zviri nyore muzvinonyungudutsa zvinodhaka zvakadai semethanol uye ethanol, zvinonyungudika zviri nyore mune zvisiri-polar zvinonyungudutsa senge n-hexane uye ether, uye zvisinganyungudika mumvura. OEA iamphiphilic molecule yagara ichishandiswa seyakagadziriswa uye detergent muindasitiri yemakemikari. Nekudaro, kumwe kutsvagurudza kwakawana kuti OEA inogona kushanda se lipid inosaina molecule mune gut-brain axis uye kuratidza nhevedzano yezviitiko zvipenyu mumuviri, zvinosanganisira: kudzora havi, kuvandudza lipid metabolism, kusimudzira ndangariro uye cognition uye mamwe mabasa. Pakati pavo, mabasa eOleoylethanolamide ekudzora chishuwo uye kuvandudza lipid metabolism akatambira zvakanyanya.
Oleoylethanolamide inogona kudzora kudya kwekudya uye simba homeostasis nekuita peroxisome proliferator-activated receptor-α. Pamusoro pezvo, Oleoylethanolamide inoratidza zvimwe zviitiko zvine chekuita nehutano, zvinosanganisira modulating converter chiitiko munzira ye lysosomal-ku-nuclear inoratidzira yakabatana nekugara kwenguva refu mutemo uye kudzivirira tsinga dzinodzora hunhu hwekuora mwoyo. Tsvagiridzo inoratidzawo kuti Oleoylethanolamide inogona kuve neuroprotective mhedzisiro. Mumienzaniso yemhuka, yakawanikwa ichideredza kukuvadzwa kubva mukurohwa uye kukuvara kwehuropi. Iyo yekudzora mhedzisiro yeOleoylethanolamide inonzi inoenderana nekusunga kwayo kuPPARα, iyo inodzikira neiyo retinoid X receptor (RXR) uye inoimisa sechinhu chine simba chinyorwa chinobatanidzwa mukubatanidza simba homeostasis, lipid metabolism, autophagy, uye kuzvimba. zvinonangwa pasi pemvura.
Feature
(1) Kuchena kwepamusoro: OEA inogona kuwana yakakwira-kuchena zvigadzirwa kuburikidza nekunatsa maitiro ekugadzira. Kuchena kwepamusoro kunoreva zvirinani bioavailability uye kushoma kwakashata maitiro.
(2) Chengetedzo: OEA yakaratidza kuve yakachengeteka kumuviri wemunhu.
(3) Kugadzikana: OEA ine kugadzikana kwakanaka uye inogona kuchengetedza basa rayo uye mhedzisiro pasi pezvakasiyana nharaunda uye kuchengetedza mamiriro.
(4) Zviri nyore kutora: OEA inogona kukurumidza kubatwa nemuviri wemunhu uye kugoverwa kune akasiyana matishu uye nhengo.
Applications
Oleoylethanolamide ndeye yakasikwa ethanolamide lipid inoshandiswa sechikafu kuronga uye uremu hwemuviri kudzora mumhando dzakasiyana dze vertebrate. Iyo metabolite yeoleic acid inoumbwa mudumbu remunhu. Oleylethanolamide (OEA) imorekuru inogadzirisa lipid metabolism uye simba rembaostasis. Inonamatira kuPPAR Alpha receptors uye inobatsira kudzora zvinhu zvina: nzara, mafuta emuviri, cholesterol uye uremu. PPAR Alpha inomiririra peroxide proliferator-activated receptor alpha, uye bioactive lipid amide oleoylethanolamide (OEA) ine zvakasiyana-siyana zvakasiyana-siyana zvekumba, kusanganisira anti-inflammatory activity, immune response modulation, uye antioxidant effects.
