Munyika yanhasi inomhanya-mhanya, kugona kwedu kurangarira nekudzidza ruzivo rutsva kunoita basa rakakosha muhupenyu hwedu pachedu nehunyanzvi.Kunyangwe iwe uri kugadzirira bvunzo yakakosha, kutsvaga kufambira mberi kwebasa, kana kuvavarira kuvandudza hunyanzvi hwako hwekufunga, kugadzirisa ndangariro yako nehunyanzvi hwekudzidza ndicho chinhu chakakosha.Nekubatanidza nefiracetam mumaitiro ako ezuva nezuva, unogona kuwana kuvandudzwa kunoshamisa mundangariro, kuziva uye kudzidza.
Nefiracetam is anootropic compoundiyo ndeyemhuri yeracetam.Inozivikanwa nemhedzisiro yayo yekuziva-inosimudzira, inowanzoshandiswa seyamuro yekudzidza kana kutsigira kushanda kwepfungwa.Nefiracetam inozivikanwa nekukwanisa kwayo kuvandudza chiyeuchidzo, kudzidza, uye kugona kwekuziva.
Nefiracetam yakagadzirwa muJapan mumakore ekuma1990 uye yakarongeka yakafanana nemamwe marudzi emarudzi akadai sepiracetam uye aniracetam.Zvisinei, nefiracetam inomira kunze kwemaitiro ayo akasiyana ekuita.Inosimudzira basa reiurotransmitter receptors muuropi, kunyanya glutamate receptors, iyo yakakosha pakudzidza nekurangarira maitiro.
Nefiracetam yakaratidza mhedzisiro yakanaka pakuyeuka uye kugona kudzidza.Inowedzera kuburitswa kwemaurotransmitters senge acetylcholine, iyo inoita basa rakakosha mukuziva maitiro.Nokugadzirisa idzi neurotransmitter systems, nefiracetam inosimudzira synaptic plasticity, neuronal survival, uye neuroprotection, pakupedzisira inovandudza ndangariro kuumbwa uye kudzosa.
Pamusoro pezvo, inogona kutsigira hutano hwehuropi hwese nekudzivirira oxidative kusagadzikana uye kuderedza kuunganidzwa kwezvinhu zvinokuvadza muuropi.Iyi neuroprotective mhedzisiro inoita kuti ive mukana wemushonga wekurapa zvirwere zvetsinga senge chirwere cheAlzheimer uye dementia.
Nzira yekuita nefiracetam yakaoma uye haisati yanyatsonzwisiswa.Nekudaro, kutsvagisa kunopa imwe nzwisiso yekuti iyi nootropic inoshandisa sei kugona-inosimudzira mhedzisiro.
Kutanga, nefiracetam inozivikanwa kugadzirisa acetylcholine neurotransmission.Acetylcholine ndiyo yakakosha neurotransmitter inobatanidzwa mukudzidza, ndangariro uye kutarisisa.Nokuwedzera kusunungurwa uye kutora kweacetylcholine muuropi, nefiracetam inokurudzira kukurukurirana zviri nani pakati peeuroni uye inowedzera kuumbwa kwekuyeuka nekudzorera.
Mukuwedzera, nefiracetam yakawanikwa kuwedzera basa re glutamate receptors, kunyanya AMPA uye NMDA receptors.Glutamate ndiyo yakakura inonakidza neurotransmitter muuropi uye inoita basa rakakosha mu synaptic plasticity ine chekuita nekudzidza uye ndangariro maitiro.Nokuwedzera basa rezvibvumirano izvi, nefiracetam inokurudzira synaptic plasticity, nokudaro inovandudza ruzivo rwekuziva.
Pamusoro pemigumisiro yayo paacetylcholine uye glutamate, nefiracetam inobatawo mamwe maitiro eurotransmitter.Yakaratidzwa kuti igadzirise iyo kusunungurwa uye chiito che gamma-aminobutyric acid (GABA), iyo huru inhibitory neurotransmitter muuropi.Nokugadzirisa GABAergic neurotransmission, nefiracetam inosimudzira homeostasis ye neuronal basa uye inodzivirira hyperexcitability iyo inogona kukanganisa kugona kwekuziva.
Mukuwedzera, nefiracetam yakawanikwa iine neuroprotective properties.Inobatsira kuderedza reactive oxygen marudzi (ROS) kugadzirwa uye kudzivirira oxidative kusagadzikana, izvo zvinogona kukonzera neuronal kukuvara uye kukanganisa cognitive basa.Iyi neuroprotective mhedzisiro inoita kuti nefiracetam ive inovimbisa mushonga mumiriri wekurapa neurodegenerative zvirwere zvakaita sechirwere cheAlzheimer.
Iyo chaiyo nzira iyo nefiracetam inoshandisa yayo neuroprotective mhedzisiro haina kunyatsonzwisiswa.Zvisinei, inofungidzirwa kuti inobatanidzwa mukugadzirisa kweuropi cell calcium homeostasis, activation ye antioxidant nzira, uye kudzvinyirirwa kwemaitiro ekuputira.Idzi nzira dzakasiyana-siyana dzinoita kuti pave nekuziva kwekusimudzira kunopiwa nefiracetam.
◆kuwedzera chiyeuchidzo
Memory chinhu chakakosha chekushanda kwedu kwenjere, ichitibvumira kuchengeta nekurangarira ruzivo.Nefiracetam yakaratidza mhedzisiro inovimbisa mukusimudzira chiyeuchidzo, kunyanya kune vanhu vane ndangariro kukanganisa.Nokuwedzera kusunungurwa kwemaurotransmitters anokosha akadai seacetylcholine, nefiracetam inokurudzira nzvimbo dzekuyeuka dzeuropi, zvichibatsira kuumba uye kusimbisa zviyeuchidzo.
Nokuwedzera kusunungurwa kwemaurotransmitters se dopamine uye serotonin, nefiracetam inogona kuwedzera kuchenjerera uye kubatsira kubvisa zvipingamupinyi.Izvi zvinogona kunatsiridza kudzidza nekudzidza zvakanyanya, zvichibvumira vanhu kuti vatore ruzivo zvakanyanya uye nekurichengeta kwenguva yakareba.
Uyezve, nefiracetam yakawanikwa kukurudzira synaptic plasticity, kukwanisa kwehuropi kugadzirisa nekusimbisa hukama pakati peeuroni.Izvi zvinovandudza ndangariro uye zvinoita kuti zvive nyore kutora ruzivo pazvinenge zvichidiwa.
◆kunatsiridza kugona kudzidza
Kudzidza ndiro musimboti wekukura nekukura kwemunhu.Kugona kweNefiracetam kusimudzira nzira dzekudzidza dzehuropi kunoita kuti ive chishandiso chakakosha kune vanhu vazhinji vari kutsvaga kugona hunyanzvi hutsva zviri nyore.
Tsvagiridzo yakaratidza kuti nefiracetam inowedzera kuburitswa kwemaurotransmitters senge glutamate, iyo inoita basa rakakosha musynaptic plasticity uye kudzidza.Izvi zvinobvumira uropi kuumba uye kusimbisa hukama zvakanyanya, izvo zvinogonesa kudzidza.
Pamusoro pezvo, nefiracetam yakawanikwa ichisimudzira kutarisa uye kuisa pfungwa, zvichibvumira vanhu kuti vanyure zvizere mukuita kwekudzidza.Nekudzikisa zvinotsausa nekuvandudza nguva yekutarisisa, inovhura nzira yekudzidza kunobudirira uye kunoshanda.
◆Dosege:
Iyo yakakwana dose ye nefiracetam inosiyana kubva kumunhu kuenda kumunhu, zvichienderana nezvinhu zvakaita sezera, uremu, hutano hwakakwana, uye zvakanangana nezvinangwa zvekufunga.Zvakakosha kutanga nedosi yakaderera uye zvishoma nezvishoma kuwedzera muyero sezvinodiwa, sezvo munhu mumwe nomumwe angapindura zvakasiyana kune imwe nzvimbo.
◆Nhungamiro:
1. Nguva dzose bvunzurudza nyanzvi yehutano: Usati waisa nefiracetam kana chero imwe itsva yekuwedzera muhutano hwako, zvinokurudzirwa kubvunza nyanzvi yehutano.Vanogona kupa zano remunhu zvichienderana nemamiriro ako akasiyana uye kubatsira kuona dosi uye hurongwa hwekushandisa hwakakunakira iwe.
2. Tevedzera chipimo chinokurudzirwa: Nyatsotevedzera zvinokurudzirwa dosage nhungamiro uye dzivisa kudarika chipimo chemushonga pasina zano renyanzvi.Kuwedzera dhigirii kupfuura inokurudzirwa inogona kukonzera zvisingadiwe mhedzisiro kana kuderedza mhedzisiro yaunoda.
3. Cyclic kushandiswa kwenefiracetam: Kuti udzivirire kushivirira kana kuvimba, zvinokurudzirwa kushandisa nefiracetam cyclically.Kutenderera kwakajairika mazuva mashanu kusvika matanhatu ebasa achiteverwa nemazuva maviri ekuzorora.Izvi zvinobvumira muviri wako kugadzirisa uye kuchengetedza kushanda kweiyo nootropic.
4. Iva nemoyo murefu: Migumisiro ye nefiracetam inogona kunge isingakurumidzi kuoneka sezvo inowanzotora nguva yekusimbisa muhurongwa.
Mubvunzo: Pane zvingangoitika zveNefiracetam here?
A: Vamwe vashandisi vakashuma zvakapfava mhedzisiro yakadai semusoro, dzungu, kuda kurutsa, uye kusagadzikana kwemudumbu.Izvi zvinokonzeresa kazhinji hazviwanzo uye ndezvenguva pfupi.Zvakakosha kuziva kuti zviitiko zvemunhu zvinogona kusiyana, uye kana ukasangana nemhedzisiro yakaipa, zvinokurudzirwa kurega kushandisa uye kubvunza nyanzvi yezvehutano.
Mubvunzo: Nefiracetam yakachengeteka kushandisa here?
A: Nefiracetam inowanzoonekwa yakachengeteka kana yakashandiswa sezvinorayirwa.Yakave yakatenderwa muzvidzidzo zvakawanda, ine mishoma mhedzisiro yakataurwa.Nekudaro, zvinogara zvichikurudzirwa kubvunzana nenyanzvi yezvehutano usati watanga chero chitsva chekuwedzera, kunyanya kana uine chero mamiriro ezvehutano aripo kana uri kutora mimwe mishonga.
Disclaimer: Ichi chinyorwa ndechezvinangwa zveruzivo chete uye hachifanirwe kutorwa sezano rekurapa.Nguva dzose bvunza nyanzvi yezvehutano usati washandisa chero chekuwedzera kana kushandura hutano hwehutano hwako.
Nguva yekutumira: Aug-15-2023
