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YDL223C (HBT1) mugadziri wehupfu CAS Nhamba: 489408-02-8 99% kuchena min. zvekuwedzera zvinhu

Tsanangudzo Pfupi

HBT1 inosungira kune ligand-binding domain ye-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA-R) nenzira inotenderera-glutamate.


Product Detail

Product Tags

Product Vhidhiyo

Product Parameters

Product name

HBT1

Rimwe zita

YDL223C

CAS Nha.

489408-02-8

Molecular formula

C16H17F3N4O2S

Molecular uremu

386.40

Kuchena

99.0%

Chitarisiko

Chiedza chero chakasimba

Packing

1kg pabhegi 25kg padhiramu

Application

nootropics

Product sumo

HBT1 inosungira kune ligand-binding domain ye-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA-R) nenzira inotenderera-glutamate. Izvi zvinoreva kuti HBT1 imorekuru rinongosunga kune imwe nzvimbo paprotein ye AMPA-R kana glutamate iripo, uye kusunga uku kunobatsira kugadzirisa kushanda kweprotein. AMPA receptors inoratidzwa mukati mepakati tsinga sisitimu uye inoita basa rakakosha mukutaurirana neuronal, kugadzirisa manzwiro, kudzidza, ndangariro, uye synaptic plasticity. AMPA receptors ndiwo anobatsira zvikuru mukunakidza neurotransmission, kupindira nekukurumidza, nekukasira kudzima manyawi pamasynapses mazhinji, uye anobatanidzwa mumhinduro dzekutanga kune glutamate munzvimbo dzesynaptic. AMPA receptors anowanzo kutaurwa pamwe neNMDA receptors pamasynapses, uye pamwe chete vanosimudzira synaptic plasticity maitiro anosanganisirwa mukudzidza, ndangariro, excitotoxicity, uye neuroprotection. Brain-derived neurotrophic factor (BDNF) inonzi neurotrophic factor inoita basa rinokosha mukuchengetedza uye kuwedzera kwemasero uye ine simba uye yakawanda migumisiro pakupararira, kusiyanisa, kurarama uye kufa kwemasero emagetsi uye asina-neuronal. , neurotransmitter modulator inobatsira neuronal plasticity mukudzidza nekuyeuka. Nokudaro, zvakakosha kune hutano uye hutano hwehutano hwehutano.

Feature

(1) Kuchena kwepamusoro: HBT1 inogona kuwana yakakwirira-kuchena zvigadzirwa kuburikidza nekunatsa maitiro ekugadzira. Kuchena kwepamusoro kunoreva zvirinani bioavailability uye kushoma kwakashata maitiro.

(2) Chengetedzo: HBT1 yakaratidza kuve yakachengeteka kumuviri wemunhu.

(3) Kugadzikana: HBT1 ine kugadzikana kwakanaka uye inogona kuchengetedza basa rayo nekuita pasi pemamiriro akasiyana-siyana uye kuchengetedza mamiriro.

Applications

HBT1 inyowani AMPA receptor enhancer ine low agonism, iyo inonyandura kugadzirwa kwebrain-derived neurotrophic factor (BDNF) uye ine zvishoma agonistic mhedzisiro pamaprimary neurons. HBT1 inosungira kune ligand-binding domain ye AMPA-R nenzira inotsamira paglutamate. Pamwe chete, vanosimudzira synaptic plasticity maitiro anobatanidzwa mukudzidza, ndangariro, kunakidzwa, uye neuroprotection. Inogona kuvandudza kugona kwehuropi nekurangarira, uye kuwedzera kugona kwevanhu kudzidza. Inowanzowedzerwa kune kudya kwezuva nezuva nenzira yezvokudya zvinowedzera.


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