Iamino acid ipi inoshandurwa kubva kuspermine? Basa rayo nderei?

Urumechinhu chakakosha che polyamine chinowanikwa zvakanyanya muzvisikwa, kunyanya chichiita basa guru mukukura kwemasero. Urume hunoshandurwa kubva kuma amino acids arginine ne ornithine. Chinyorwa chino chichaongorora kwakabva, kushanda uye kukosha kweurume muzvisikwa.

Manyuko eSpermine

Kugadzirwa kwespermine kunonyanya kuenderana nekushandiswa kwemaamino acids. Chekutanga, ornithine ndiyo inotungamira kugadzirwa kwespermine, iyo inogona kugadzirwa ne decarboxylation reaction ye arginine. Maitiro chaiwo ndeaya anotevera:

Arginine inoshandurwa kuita ornithine: Pasi pe catalysis yema enzymes, arginine inobviswa kabhokisaidhi kuti igadzire ornithine.
Kushandurwa kweornithine kuita spermine: Ornithine inosanganiswa zvakare neamino acid (kazhinji amino acid alanine) uye, kuburikidza nemaitiro akasiyana-siyana enzymatic, pakupedzisira inoumba spermine.
Maitiro aya ekushandura haangosanganisiri chete kushandiswa kwemaamino acids, asiwo ane chekuita nekukura, kupatsanurwa uye kugadziriswa kwemasero.

Mhedzisiro yehurume muzvisikwa

Urume hune mabasa akawanda akakosha muhupenyu hwezvinhu zvipenyu, kunyanya kusanganisira zvinotevera:

Kuwanda kwemasero uye kukura kwawo: Urume hunoita basa rakakosha mukudzora kutenderera kwemasero. Ongororo dzakaratidza kuti urume hunogona kukurudzira kupararira kwemasero, kunyanya mukugadzirisa nekuvandudza tishu. Hunokurudzira kupatsanurwa nekukura kwemasero nekudzora kuratidzwa kwemapuroteni ane chekuita nekutenderera kwemasero.

Mhedzisiro yeAntioxidant: Urume hune simba reAntioxidant, rinogona kubvisa mafree radicals mumuviri uye kuderedza kukuvara kwemasero kunokonzerwa nekushushikana kweoxidative. Izvi zvinoita kuti urume huve nekushandisa kwakakosha mukunonoka kukwegura uye kudzivirira zvirwere zvine chekuita nekukwegura.

Kudzora kuratidzwa kwemajini: Urume hunogona kudzora kuratidzwa kwemajini nekusunga kuDNA neRNA. Izvi zvakakosha pakushanda kwemasero uye mamiriro emuviri, kunyanya mukupindura kune zvinokurudzira zvekunze nekushushikana.

Zvinokurudzira apoptosis: Mune mamwe mamiriro ezvinhu, urume hunogonawo kukurudzira apoptosis (kufa kwemasero kwakarongwa), izvo zvakakosha pakuchengetedza homeostasis yemasero uye hutano hwematishu.

Kuchinja-chinja kwesimba remuviri: Kushandiswa kwembeu yemurume kunoitawo basa rakakosha mukudzivirira muviri. Kunogona kuwedzera mashandiro emasero emuviri uye kuwedzera simba remuviri rekudzivirira hutachiona nezvirwere.

Urume uye Hutano

Sezvo tsvakiridzo pamusoro pembeu yemurume nemukadzi ichiwedzera, humbowo hwakawanda hunoratidza kutimbeu yemurume nemukadzi ine chekuita nematambudziko akasiyana-siyana ehutano. Semuenzaniso, huwandu hwembeu yemurume nemukadzi hune chekuita nekuitika uye kukura kwezvirwere zvakasiyana-siyana zvakaita sekukwegura, chirwere chemwoyo, uye kenza.

Kukwegura: Ongororo dzakawana kuti huwandu hwembeu dzinobuda mumuviri hunowedzera kuderera panguva yekukwegura, uye kuwedzerwa kwembeu dzinobuda mumuviri kunogona kubatsira kunonoka kukwegura uye kuvandudza hutano hwevakuru.

Hutano hweMwoyo neMwoyo: Urume hunobatsira pakudzivirira mwoyo neropa, huchivandudza mashandiro emuviri uye huchideredza njodzi yezvirwere zvemwoyo.

mukupedzisa

Semorekuru inokosha yezvebhayoloji, urume hunonyanya kubva mukushandiswa kwemaamino acids, kunyanya kushandurwa kwearginine neornithine. Urume hunoita basa rakakosha mukuwanda kwemasero, kurwisa oxidation, kutonga kwekugadzirwa kwemajini, nezvimwewo, uye hunokosha pakuchengetedza hutano nekushanda kwezvisikwa. Nekudzidza kwakadzama kweurume, ruzivo rwakawanda nezvebasa rahwo muhutano nezvirwere runogona kuwanikwa mune ramangwana, zvichipa mazano matsva nenzira dzekudzivirira nekurapa zvirwere zvine chekuita nazvo.

Nekunzwisisa kwakabva uye kushanda kwespermine, tinogona kunzwisisa kukosha kwayo mumabasa ehupenyu uye kupa hwaro hwesainzi hwekusimudzira hutano nekunonotsa kukwegura. Tinotarisira kuti tsvakiridzo yeramangwana icharatidza zvakare mashandisirwo anogona kuitwa spermine uye ichapa mipiro yakakura kuhutano hwevanhu.

Chiziviso: Iyi webhusaiti inoburitsa kana kudhindazve chinyorwa ichi nechinangwa chekupa nekugovana rumwe ruzivo, uye hazvirevi kuti inobvumirana nemaonero ayo kana kusimbisa tsananguro yayo. Kana paine chikanganiso pakumaka kwenzvimbo yacho kana kukanganisa kodzero dzenyu dzepamutemo, ndapota taurai newebhusaiti iyi muine humbowo hwekuti muridzi wayo ndewei, uye tichagadzirisa kana kuidzima nenguva. Mazvita.