Zvaunofanira kuziva nezvekukwegura uye nzira dzaungashandisa kuti uderedze kukwegura

Vanhu vachikura, vazhinji vari kutsvaga nzira dzekudzikisa kukwegura uye kuchengetedza chitarisiko chevechidiki uye simba. Kune nzira dzakasiyana-siyana dzinogona kushandiswa kubatsira kuderedza kukwegura uye kukurudzira hutano nekugara zvakanaka.

Ongororo yazvino inoratidza kuti kukwegura hakungoitiki zvishoma nezvishoma chete, asi kunotangawo panguva yakatarwa pakati pemakore makumi mana nemana nemakumi matanhatu.

Kutanga mumakore ako ekutanga ekuma40, metabolism yemafuta nedoro inochinja, ukuwo mashandiro eitsvo dzako, metabolism yemacarbohydrate, uye immune system zvinotanga kudzikira pazera remakore makumi matanhatu. Vaongorori vakaonawo shanduko huru panjodzi yeganda, tsandanyama uye chirwere chemwoyo pakati pemakore makumi mana nemakumi matanhatu.

Chidzidzo ichi chaisanganisira vanhu vekuCalifornia zana nevasere chete vane makore ari pakati pe25 ne75, uye kutsvagurudza kwakawanda kunodiwa kusimbisa zvakawanikwa. Zvisinei, zvakawanikwa izvi zvinogona kutungamira mukuongororwa kutsva uye nzira dzekudzivirira zvirwere zvine chekuita nekukwegura.

Kurarama kwenguva refu hazvirevi hazvo kuti munhu mukuru ane hutano kana kuti anofara. Sekureva kwemunyori mukuru wechidzidzo ichi Dr. Michael Snyder, director weCenter for Genomics and Personalized Medicine paStanford University, kuvanhu vazhinji, avhareji ye "healths length" yavo - nguva yavanopedza vaine hutano hwakanaka - yakareba kupfuura nguva yavo yehupenyu ipfupi yemakore 11-15.

Hupenyu hwepakati pehupenyu hwakakosha pakukwegura kwakanaka

Ongororo yapfuura yakaratidza kuti hutano hwako pakati pehupenyu (kazhinji pakati pemakore makumi mana nemazana matanhatu nemashanu) hune basa rakakosha pahutano hwako gare gare muhupenyu. Chidzidzo che2018 mujenari reNutrition chakabatanidza zvinhu zvakasiyana-siyana zvemararamiro pakati pehupenyu, zvakaita sehuremu hwakanaka, kushanda nesimba, kudya chikafu chakanaka uye kusaputa fodya, nekuvandudza hutano panguva yekukwegura.

Mushumo wakabudiswa mujenari ra2020 wakaratidzawo kuti pakati pehupenyu inguva yakakosha yekuchinja kwehutano hwehuropi. Kudzora BP uye kuramba uchishamwaridzana, mukufunga uye mumuviri panguva ino yehupenyu kunogona kubatsira kuderedza njodzi yekuora mwoyo mushure menguva refu, mushumo wacho wakadaro.

Chidzidzo chitsva ichi chinowedzera basa rekutsvagisa kwehealthspan uye chinoratidza kukosha kwekuvandudza mamwe maitiro emararamiro achiri mudiki.

"Kuti une hutano hwakadini kana wava nemakore 60, 70 kana 80 zvinoenderana nezvawakaita mumakumi emakore apfuura," akadaro Kenneth Boockvar, MD, director weCenter for Integrated Research on Aging paYunivhesiti yeAlabama kuBirmingham. "Asi haana kubatanidzwa muchidzidzo ichi.

Akawedzera kuti zvainge zvatotanga kare kupa mazano chaiwo zvichibva pane tsvakiridzo itsva, asi kuti vanhu vanoda kugara vaine hutano mumakore avo ekuma60 vanofanira kutanga kutarisisa kudya kwavo uye mararamiro avo mumakore avo ekuma40 ne50.

Kukwegura hakudzivisiki, asi kuchinja mararamiro kunogona kuwedzera hupenyu hune hutano

Ongororo itsva yakawana kuti mamorekuru netupukanana twune chekuita nekukwegura zvinodzikira panguva dzakatarwa dzehupenyu, asi tsvakiridzo yeramangwana inodiwa kuti ione kana shanduko dzakafanana dzemamorekuru dzichiitika mumapoka akasiyana.

"Tinoda kuongorora vanhu vakawanda munyika yese kuti tione kana zvatakaona zvichishanda kune wese munhu - kwete kuvanhu vari muBay Area chete," akadaro Snyder. "Tinoda kuongorora musiyano uripo pakati pevarume nevakadzi. Vakadzi vanorarama kwenguva yakareba uye tinoda kunzwisisa kuti sei."

Kukwegura hakudzivisiki, asi dzimwe shanduko dzemararamiro dzinogona kubatsira kuderedza njodzi yezvirwere zvine chekuita nekukwegura. Zvisinei, zvimwe zvinhu zvakawanda zvakaita senharaunda, kugadzikana kwemari, hutano uye mikana yedzidzo zvinopesvedzerawo mhedzisiro yakanaka yekukwegura uye zvakaoma kuti vanhu vazvidzore.

Vanhu vanogona kuchinja mararamiro avo zvidiki zvakaita sekugara vaine mvura yakakwana kuti varambe vaine hutano hweitsvo, kuvaka tsandanyama nekurovedza muviri uye kutora mishonga yecholesterol kana cholesterol yeLDL yakakwira, akadaro Snyder.

Akawedzera kuti: "Izvi zvingasamisa kukwegura, asi zvichaderedza matambudziko atinoona uye zvichabatsira kuwedzera hupenyu hwevanhu hune hutano."

Chii chingaitwe kuti munhu anonoke kukwegura?

Chimwe chezvinhu zvinonyanya kukosha pakunonoka kukwegura kuchengetedza mararamiro ane hutano. Izvi zvinosanganisira kudya chikafu chakakwana chakapfuma mumichero, miriwo, zviyo zvese uye mapuroteni asina mafuta akawanda. Kudzivisa chikafu chakagadziriswa, shuga yakawandisa, uye mafuta asina hutano kunogona kubatsira kuderedza kuzvimba mumuviri uye kutsigira hutano hwese. Kugara uine mvura yakakwana nekunwa mvura yakawanda kwakakoshawo pakuchengetedza ganda nenhengo dzakagwinya.

Kurovedza muviri nguva dzose chimwe chinhu chakakosha pakurarama hupenyu hune hutano uye kunogona kubatsira kuderedza kukwegura. Kurovedza muviri kunobatsira kuvandudza hutano hwemwoyo, kuchengetedza tsandanyama, uye kutsigira kufamba-famba uye kuchinjika. Kutora chikamu muzviitiko zvakaita sekufamba, kushambira, yoga kana kurovedza muviri kunogona kubatsira muviri wako kutaridzika semudiki uye une simba.

Pamusoro pekudya uye kurovedza muviri, kudzora kushushikana kwakakosha mukudzora kukwegura. Kushushikana kwenguva refu kunogona kuva nemigumisiro yakaipa pamuviri, zvichikonzera kuzvimba kwakanyanya uye kushomeka kwemasoja emuviri. Kudzidzira nzira dzekuderedza kushushikana dzakadai sekufungisisa, kufema zvakadzika, kana kufunga kunogona kubatsira kukurudzira kuzorora uye kugara zvakanaka.

Chimwe chinhu chakakosha pakunonoka kukwegura kuwana hope dzakakwana. Kurara kwakakosha kuti muviri ugadziriswe uye ugadziriswe, uye kushaya hope dzakanaka kunogona kukonzera kukwegura nguva isati yakwana. Kuronga purogiramu yekurara nguva dzose uye kugadzira nguva yekurara inozorodza kunogona kubatsira kuvandudza kunaka kwekurara uye kutsigira hutano hwese.

Pamusoro pemararamiro, kune nzira dzakasiyana-siyana dzekurapa dzinogona kubatsira kuderedza kukwegura. Izvi zvinogona kusanganisira nzira dzekuchengetedza ganda, nzira dzekuchenesa, uye nzira dzekurapa. Kushandisa mafuta ekudzivirira zuva uye kunyorovesa ganda rako kunogona kubatsira kudzivirira kukuvara kwezuva uye kuchengetedza chitarisiko cheudiki. Nzira dzekuchenesa dzakadai seBotox, fillers, uye laser treatments zvinogonawo kubatsira kuderedza kutaridzika kwemakwinya uye mitsetse midiki.

Pamusoro pezvo, kune zvimwe zvinovaka muviri zvinodzivirira kukwegura zviripo zvinogona kutsigira hutano hwese uye simba. Pakati pezvinowedzera zvine humbowo hwesainzi hunotsigira basa razvo mukuvandudza hutano hwemitochondrial uye kunonoka kukwegura pane zvinotangira NAD+ uye urolithin A.

zvinovaka muviri zveNAD+

Kune mitochondria, kune NAD+ (nicotinamide adenine dinucleotide), molecule inodiwa pakuwedzera kugadzirwa kwesimba. NAD+ inodzikira nekukura, izvo zvinoita sekunge zvinoenderana nekuderera kwebasa remitochondrial nekuda kwezera.

Tsvagiridzo inoratidza kuti nekuwedzera NAD+, unogona kuwedzera kugadzirwa kwesimba remitochondrial uye kudzivirira kushushikana kunokonzerwa nekukwegura. Mishonga yeNAD+ inogona kuvandudza mashandiro emhasuru, hutano hwehuropi, uye kugaya chikafu ukuwo ichirwisa zvirwere zvinokanganisa tsinga. Pamusoro pezvo, inoderedza kuwedzera uremu, inovandudza insulin sensitivity, uye inogadzirisa mazinga emafuta mumuviri, senge kuderedza LDL cholesterol.

Coenzyme Q10

Kufanana neNAD+, coenzyme Q10 (CoQ10) inoita basa rakananga uye rakakosha mukugadzirwa kwesimba remitochondrial. Kufanana neastaxanthin, CoQ10 inoderedza oxidative stress, chinhu chinobva mukugadzirwa kwesimba remitochondrial iro rinoipa kana mitochondria isina hutano. Kuwedzera neCoQ10 kunoderedza njodzi yekurohwa nemoyo, sitiroko uye rufu. Tichifunga kuti CoQ10 inoderera nekukura, kuwedzera neCoQ10 kunogona kupa mabhenefiti ehupenyu hurefu kune vakwegura.

Urolithin A

Urolithin A (UA) inogadzirwa nemabhakitiriya edu emudumbu mushure mekudya polyphenols inowanikwa muzvikafu zvakaita semapomegranate, mastrawberry, uye walnuts. Kuwedzera UA mumakonzo ane makore epakati nepakati kunobatsira sirtuins uye kunowedzera simba reNAD+ nemasero. Zvakakosha, UA yakaratidzwa kuti inobvisa mitochondria yakakuvara kubva mutsandanyama dzevanhu, nokudaro ichivandudza simba, kuramba kuneta, uye kushanda zvakanaka kwemitambo. Nokudaro, kuwedzera UA kunogona kuwedzera hupenyu nekudzivirira kukwegura kwetsandanyama.

Spermidine

Kufanana neNAD+ neCoQ10, spermidine imorekuru inongoerekana yavapo inoderera nekukura. Kufanana neUA, spermidine inogadzirwa nemabhakitiriya emudumbu medu uye inokonzera mitophagy - kubviswa kwe mitochondria isina hutano uye yakakuvara. Zvidzidzo zvembeva zvinoratidza kuti kuwedzerwa kwe spermidine kunogona kudzivirira kubva kuzvirwere zvemwoyo nekukwegura kwekubereka kwevakadzi. Pamusoro pezvo, spermidine yekudya (inowanikwa muzvikafu zvakasiyana-siyana zvinosanganisira soya nezviyo) yakavandudza ndangariro mumakonzo. Tsvagiridzo yakawanda inodiwa kuti uone kana zvakawanikwa izvi zvichigona kudzokororwa muvanhu.

Suzhou Myland Pharm & Nutrition Inc. ikambani yakanyoreswa neFDA inopa upfu hweUrolithin A hwemhando yepamusoro uye hwakachena.

KuSuzhou Myland Pharm takazvipira kupa zvigadzirwa zvemhando yepamusoro nemitengo yepamusoro. Upfu hwedu hweUrolithin A hunoongororwa zvakasimba kuti hune kuchena uye simba, zvichiita kuti uwane chinowedzera chemhando yepamusoro chaunogona kuvimba nacho. Kunyangwe uchida kutsigira hutano hwemasero, kusimbisa masoja emuviri wako kana kusimudzira hutano hwese, Upfu hwedu hweUrolithin A ndiyo sarudzo yakakwana.

Nemakore makumi matatu eruzivo uye zvichitungamirirwa netekinoroji yepamusoro uye nzira dzeR&D dzakanyatsogadzirwa, Suzhou Myland Pharm yakagadzira zvigadzirwa zvakasiyana-siyana zvinokwikwidzana uye yakava kambani itsva yekuwedzera sainzi yehupenyu, kugadzira zvinhu zvakagadzirwa uye kugadzira zvinhu.

Pamusoro pezvo, Suzhou Myland Pharm ikambani yakanyoreswa neFDA. Zvishandiso zveR&D zvekambani, nzvimbo dzekugadzira, uye zvishandiso zvekuongorora ndezvemazuva ano uye zvinoshanda zvakawanda, uye zvinogona kugadzira makemikari kubva pamamirigiramu kusvika kumatani muhukuru, uye zvinoenderana neISO 9001 standards uye specifications dzekugadzira GMP.