Sezvo vanhu vachikura, vazhinji vari kutsvaga nzira dzekudzikisa hurongwa uye kuchengetedza chitarisiko chechidiki uye simba. Kune nzira dzakasiyana-siyana uye maitiro anogona kushandiswa kubatsira kunonoka kukwegura uye kukurudzira hutano hwakakwana uye kugara zvakanaka.
Tsvagiridzo yazvino inoratidza kuti kuchembera hakungoitike zvishoma nezvishoma, asi zvakare kunotanga panguva yakatarwa pakati pemakore makumi mana nemana nemakumi matanhatu.
Kutanga mumakore ako ekutanga 40s, lipid yako uye doro metabolism zvinoshanduka, apo kushanda kweitsvo dzako, carbohydrate metabolism, uye mutemo wekudzivirira zvirwere zvinotanga kuderera kusvika makore makumi matanhatu. old.
Chidzidzo ichi chaisanganisira 108 chete maCalifornians ane makore makumi maviri nemashanu kusvika makumi manomwe nemashanu, uye kumwe kutsvagisa kunodiwa kusimbisa zvakawanikwa. Nekudaro, izvi zvakawanikwa zvinogona kutungamira kune mitsva yekuongorora bvunzo uye nzira dzekudzivirira zvirwere zvine chekuita nekuchembera.
Kurarama kwenguva refu hakurevi hupenyu hwekare hune hutano kana hunoshanda. Maererano nemunyori mukuru wekudzidza Dr. Michael Snyder, mutungamiriri weCentre for Genomics uye Personalized Medicine paStanford University, kuvanhu vazhinji, "avhareji yehutano" yavo - nguva yavanopedza vaine hutano hwakanaka - yakareba kudarika Hupenyu hwavo hupfupi. 11-15 makore.
Midlife yakakosha pakukwegura kune hutano
Ongororo yapfuura yakaratidza kuti hutano hwako pakati pehupenyu (kazhinji pakati pemakore e40 ne65) hunoita basa rinokosha muhutano hwako gare gare muupenyu. Chidzidzo che 2018 mujenari Nutrition chakabatanidza mararamiro ehupenyu hwepakati, zvakadai sehuremu hune hutano, kuita muviri, kudya kudya kwakanaka uye kusaputa, kuvandudza hutano panguva yekukwegura. 2
Chirevo chakaburitswa mujenari 2020 chakaratidzawo kuti midlife inguva yakakosha yekuchinja kwehutano hwehuropi. Kudzora BP uye kugara uchishamwaridzana, kuziva uye kuita muviri panguva ino yehupenyu kunogona kubatsira kudzikisa njodzi yedementia gare gare muhupenyu, mushumo wakadaro.
Chidzidzo chitsva ichi chinowedzera kumunda wekutsvagisa hutano uye chinosimbisa kukosha kwekuvandudza mamwe mararamiro ehupenyu pakutanga kwehupenyu.
"Kune hutano hwakadii kana uine makumi matanhatu, makumi manomwe kana makumi masere chaizvo zvinoenderana nezvawakaita mumakumi emakore usati wasvika," akadaro Kenneth Boockvar, MD, director weCentre for Integrated Research on Aging paYunivhesiti yeAlabama. Birmingham. ” asi haana kubatanidzwa muchidzidzo chacho.
Akawedzera kuti zvakange zvave kutanga kuita kurudziro yakanangana nekutsvagisa kutsva, asi kuti vanhu vanoda kugara vaine hutano mumakore makumi matanhatu vanofanirwa kutanga kutarisisa nezvekudya kwavo uye mararamiro avo mu40s uye 50s.
Kuchembera hakudzivisiki, asi kuchinja kwemararamiro kunogona kuwedzera hupenyu hune hutano
Tsvagiridzo nyowani inoona kuti mamorekuru nemamicroorganisms ane chekuita nekuchembera anodzikira panguva dzakatarwa dzehupenyu kutenderera, asi tsvakiridzo yeramangwana inodiwa kuti uone kana shanduko imwe chete yemamolecular inoitika muhuwandu hwakasiyana.
"Tinoda kuongorora vanhu vazhinji munyika yese kuti tione kana zvatinocherekedza zvinoshanda kumunhu wese - kwete vanhu vari muBay Area," akadaro Snyder. "Tinoda kuongorora kusiyana kwevarume nevakadzi. Vakadzi vanorarama kwenguva refu uye tinoda kunzwisisa kuti nei."
Kuchembera hakudzivisiki, asi kumwe kuchinja kwemararamiro kunogona kubatsira kuderedza njodzi yezvirwere zvine chekuita nekuchembera. Zvakadaro, zvimwe zvinhu zvakawanda zvakaita semhoteredzo, kugadzikana kwemari, hutano uye mikana yedzidzo zvinokanganisawo hutano hunobva mukuchembera uye zvakaoma kuti vanhu vadzore.
Vanhu vanogona kuita shanduko yemararamiro madiki sekugara hydrated kuchengetedza hutano hweitsvo, kuvaka tsandanyama nekudzidziswa uremu uye kutora cholesterol mishonga kana LDL cholesterol yakakwira, Snyder akadaro.
Akawedzera kuti: "Izvi zvinogona kusamisa kuchembera, asi zvinoderedza matambudziko atinoona uye zvinobatsira kuwedzera hupenyu hwevanhu vane hutano."
Chii chingaitwa kuti kunonotse kuchembera?
Chimwe chezvinhu zvinonyanya kukosha mukuderedza kuchembera kuchengetedza mararamiro ane hutano. Izvi zvinosanganisira kudya kudya kwakakwana kwakapfuma mumichero, miriwo, zviyo uye mapuroteni asina kusimba. Kudzivisa kudya kwakagadzirwa, shuga yakawandisa, uye mafuta asina kunaka zvinogona kubatsira kuderedza kuzvimba mumuviri uye kutsigira hutano hwese. Kugara uine hydrated nekunwa mvura yakawanda kwakakoshawo kuchengetedza hutano hweganda uye nhengo.
Kugara uchirovedza muviri ndechimwe chinhu chinokosha chemararamiro ane utano uye kunogona kubatsira kuderedza kuchembera. Kuita zvemuviri kunobatsira kuvandudza hutano hwemwoyo, kuchengetedza tsandanyama, uye kutsigira kufamba kwese uye kuchinjika. Kutora chikamu mumitambo yakadai sekufamba, kushambira, yoga kana kudzidziswa kwesimba kunogona kubatsira muviri wako kutaridzika semudiki uye uine simba.
Mukuwedzera kune kudya uye kurovedza muviri, kutarisira kushungurudzika kwakakosha mukuderedza kukwegura. Kusagadzikana kusingaperi kunogona kuve nemhedzisiro yakaipa pamuviri, zvichikonzera kuwedzera kuzvimba uye kushaya simba immune system. Kudzidzira maitiro ekuderedza kushushikana akadai sekufungisisa, kufema zvakanyanya, kana kufunga kunogona kubatsira kukurudzira kuzorora uye kugara zvakanaka.
Chimwe chinhu chinokosha pakuderedza kuchembera kurara zvakakwana. Kurara kunokosha kuti muviri ugadzike uye uvandudzwe, uye kushayikwa kwekurara zvakanaka kunogona kukonzera kukwegura nguva isati yakwana. Kugadzira hurongwa hwekurara hwenguva dzose uye kugadzira nguva yekurara yekuzorora kunogona kubatsira kuvandudza kunaka kwekurara uye kutsigira hutano hwese.
Pamusoro pezvinhu zvemararamiro, kune kurapa kwakasiyana-siyana kunogona kubatsira kuderedza kuchembera. Izvi zvinogona kusanganisira maitiro ekuchengeta ganda, zvizorwa, uye kupindira mune zvekurapa. Kushandisa sunscreen uye kunyorovesa ganda rako kunogona kubatsira kudzivirira kukuvara kwezuva uye kuchengetedza chitarisiko chepwere. Cosmetic maitiro akadai seBotox, mafirita, uye marapiro ekurapa anogonawo kubatsira kuderedza kutaridzika kwemakwinya uye mitsetse yakanaka.
Pamusoro pezvo, kune zvimwe zvinorwisa-kuchembera zvinowedzera zviripo zvinogona kutsigira hutano hwese uye simba. Pakati pezvekuwedzera nehumbowo hwesainzi hwekutsigira basa ravo mukuvandudza hutano hwemitochondrial uye kunonoka kuchembera ndeye NAD + precursors uye urolithin A.
NAD + zvinowedzera
Iko kune mitochondria, kune NAD + (nicotinamide adenine dinucleotide), molekuru inodiwa mukuwedzera kugadzirwa kwesimba. NAD + inodzikira nezera, zvinoita sekunge zvinoenderana nezera-ane hukama kuderera mumitochondrial basa.
Tsvagiridzo inoratidza kuti nekuwedzera NAD +, unogona kuwedzera mitochondrial simba rekugadzira uye kudzivirira kushushikana-ane zera. NAD + precursor supplements inogona kuvandudza kushanda kwemhasuru, hutano hwehuropi, uye metabolism uku uchikwanisa kurwisa zvirwere zveurourodegenerative. Pamusoro pezvo, ivo vanoderedza uremu, vanovandudza insulin senitivity, uye vanogadzirisa lipid mazinga, sekudzikisa LDL cholesterol.
Coenzyme Q10
Kufanana neNAD +, coenzyme Q10 (CoQ10) inoita basa rakananga uye rakakosha mukugadzirwa kwesimba remitochondrial. Kunge astaxanthin, CoQ10 inoderedza oxidative kusagadzikana, chibereko chemitochondrial simba rekugadzira iro rinowedzera kana mitochondria isina hutano. Kuwedzera neCoQ10 kunoderedza njodzi yekurohwa kwemoyo, sitiroko uye kufa. Tichifunga kuti CoQ10 inoderera nezera, kuwedzera neCoQ10 kunogona kupa hupenyu hurefu kune vakura.
Urolithin A (UA) inogadzirwa nemabhakitiriya emudumbu medu mushure mekudya ma polyphenols anowanikwa muzvikafu zvakaita semapomegranati, sitirobheri, uye walnuts. UA yekuwedzera mumakonzo epakati-kati inomutsa sirtuins uye inowedzera NAD + uye masero esimba mazinga. Zvakakosha, UA yakaratidzwa kujekesa mitochondria yakakuvadzwa kubva mumhasuru dzevanhu, nekudaro ichivandudza simba, kuramba kuneta, uye kuita kwemitambo. Naizvozvo, UA yekuwedzera inogona kuwedzera hupenyu nekurwisa kuchembera kwemhasuru.
Kufanana neNAD + neCoQ10, spermidine imorekuru rinongoitika rinodzikira nezera. Zvakafanana neUA, spermidine inogadzirwa nehutumbi hwedu hwemabhakitiriya uye inokonzera mitophagy - kubviswa kwemitochondria isina kunaka, yakakuvadzwa. Zvidzidzo zvembeva zvinoratidza kuti spermidine supplementation inogona kudzivirira kubva kuchirwere chemoyo uye kuchembera kwevakadzi. Uyezve, kudya spermidine (inowanikwa mune zvakasiyana-siyana zvekudya zvinosanganisira soy uye zviyo) yakavandudza chiyeuchidzo mumakonzo. Tsvagiridzo yakawanda inodiwa kuona kana zvakawanikwa izvi zvichigona kudzokororwa muvanhu.
Suzhou Myland Pharm & Nutrition Inc. ndeye FDA-yakanyoreswa mugadziri inopa yepamusoro-mhando uye yakakwirira-kuchena urolithin A hupfu.
PaSuzhou Myland Pharm takazvipira kupa zvigadzirwa zvemhando yepamusoro nemitengo yakanakisa. Yedu Urolithin A poda inoedzwa zvakasimba kuchena uye potency, kuve nechokwadi kuti iwe unowana yemhando yepamusoro yekuwedzera iwe yaunogona kuvimba nayo. Kunyangwe iwe uchida kutsigira hutano hweserura, kuwedzera immune system yako kana kuwedzera hutano hwese, yedu Urolithin A poda ndiyo sarudzo yakakwana.
Iine makore makumi matatu echiitiko uye ichisundwa nehunyanzvi hwepamusoro uye akakwenenzverwa zvakanyanya R&D mazano, Suzhou Myland Pharm yakagadzira mhando yezvigadzirwa zvemakwikwi uye ive yekuvandudza hupenyu hwesainzi yekuwedzera, tsika synthesis uye kugadzira masevhisi kambani.
Uye zvakare, Suzhou Myland Pharm zvakare iri FDA-yakanyoreswa mugadziri. Zviwanikwa zvekambani zveR&D, zvivakwa zvekugadzira, uye zviridzwa zvekuongorora ndezvazvino uye zvinoshanda-akawanda, uye zvinogona kugadzira makemikari kubva kumamirigiramu kusvika kumatani muchiyero, uye zvinoenderana neISO 9001 zviyero uye magadzirirwo ekugadzira GMP.
Disclaimer: Ichi chinyorwa ndecheruzivo rwese chete uye hachifanirwe kutorwa sechero zano rekurapa. Imwe yeruzivo rweblog post runobva kuInternet uye haina hunyanzvi. Iyi webhusaiti inongova nebasa rekugadzirisa, kufomatidza uye kugadzirisa zvinyorwa. Chinangwa chekuendesa rumwe ruzivo hachirevi kuti unobvumirana nemaonero ayo kana kusimbisa uchokwadi hwezvirimo. Nguva dzose bvunza nyanzvi yezvehutano usati washandisa chero chekuwedzera kana kuita shanduko kuhutano hwako hwehutano.
Nguva yekutumira: Sep-11-2024
