Chii chinonzi Squalene uye Nei Uchifanira Kufarira?

Sezvo vanhu vava kunyanya kunetseka nezvehutano hwavo, Squalene iri kuwana mukurumbira nekuda kwehunhu hwayo hwakanaka hwekunyorovesa uye antioxidant. Semusanganiswa wezvisikwa, Squalene inoshandiswa zvakanyanya muzvigadzirwa zvekuchengetedza ganda, zvizoro uye zvekudya. Sezvo kudiwa kwezvishandiso zvechisikigo kuri kuramba kuchiwedzera, kudiwa kweupfu hweSqualene hwemhando yepamusoro kuri kuwedzerawo mumusika.

Squalene (CAS: 111-02-4) imvura isina ruvara isina mafuta. Imusanganiswa we triterpene une chimiro che isoprene uye chinhu chakakosha munzira ye metabolism ye cholesterol yemunhu. Terpenoids inonyanya kuwanikwa mu nutraceuticals uye cosmetics. Squalene inofungidzirwa kuti ine mabhenefiti akawanda kumuviri wemunhu, anosanganisira kuderedza mafuta eropa, antioxidant, anti-inflammatory uye immune-enhancing effects. Squalene inogona kutora chikamu mu metabolism senzira yekutanga kugadzirwa kwe steroid, uye inoita basa rakakosha munzira dzekugadzira β-carotene, coenzyme Q10, vhitamini D, vhitamini E uye vhitamini K1.

Squalene inowanikwa zvakanyanya mumhuka, zvirimwa netupukanana. Inogadzirwa mu endoplasmic reticulum uye inochengetwa muma vesicles kana kutamiswa kuenda ku membrane yesero kuburikidza nema vesicles. Nekuda kwebasa rayo guru rehupenyu, inoshandiswa zvakanyanya mukudya uye zvizoro. Nzvimbo dzeindasitiri. Squalene inowanikwa muzvikafu zvakawanda, pakati pazvo mafuta echiropa eshark ane huwandu hwakanyanya, uye mafuta mashoma emiriwo akadai semafuta emuorivhi nemafuta emupunga ane huwandu hwakanyanya hwe squalene.

Squalene ine zvakawanda zvinobatsira pakugadzira muviri, zvinosanganisira kuvandudza kushivirira kwehypoxia, kudzivirira kukura kwehutachiona, kurwisa mabhakitiriya uye kurwisa kuzvimba, uye kudzora metabolism yecholesterol. Pamusoro pezvo, ine simba rekudzima okisijeni imwe chete, ichidzivirira ganda kubva mukuoxidation yemafuta uye ichidzivirira masero kubva mukukuvadzwa kweDNA ne oxidative. Chinhu ichi chinoratidzawo mabasa akasiyana-siyana akakosha emuviri akadai sekudzivirira chirwere chemwoyo uye kuwedzera dziviriro yemuviri yevanhu.

Nhanganyaya kumabasa e squalene

1. Basa reAntioxidant

Squalene inogona kudzivirira zvinobudirira kuitika kwemafree radicals mumuviri wemunhu uye inoita basa rekudzivirira muviri. Molekyuru yesqualene ine mabhondi matanhatu asina kusanganiswa uye ine simba rekudzivirira muviri.

2. Mishonga inorwisa mabhakitiriya uye inodzivirira kuzvimba

Squalene ine simba rekurwisa mabhakitiriya, kudzivirira kuzvimba uye kuuraya mabhakitiriya uye inogona kushandiswa pazvirwere zvepamuviri zvinokonzereswa nemabhakitiriya, pamwe nekutsva, maronda eganda uye zvirwere zveaphthous. Tsvagiridzo inoratidza kuti squalene inogona kukurumidzisa kupora kwemaronda nemaronda. Hunhu hwayo hwekudzivirira kuzvimba uye antioxidant hunobatsira mukupora nekukurumidza, zvichiita kuti ive chinhu chinokosha kune chero kit yekubatsira kwekutanga.

3. Mushonga wekubvisa ma "free radicals" (chinhu chinobvisa ma "free radicals"), kuwedzera simba rekudzivirira muviri.

Squalene ine simba guru rekubvisa ma free radicals uye inoita basa rakakosha mukusimudzira metabolism yemuviri. Nekumutsa metabolism, squalene inobatsira kuvandudza kupinza kwemuviri uye kushandisa zvinovaka muviri, nokudaro ichisimudzira kuchengetedza hutano. Sechikafu chinobatsira, squalene inoshandiswa muzvigadzirwa zvakasiyana-siyana zvehutano, zvakaita sezvekudya zvinovaka muviri, zvekudya zvine hutano, uye zvinwiwa zvinoshanda. Kutsvagurudza nekushandisa squalene kuri kuramba kuchikura, zvichipa vanhu mikana yakawanda yekuwana mabhenefiti ehutano kuburikidza nechikafu.

4. Inonyorovesa uye inorwisa mabhakitiriya

Squalene ine mabhenefiti akawanda pahutano hweganda, anosanganisira dziviriro kubva kumwaranzi yeUV uye antioxidant. Inovandudza magadzirirwo eganda, inoderedza maburi nemakwinya, uye inonyorovesa ganda pasina kukonzera kushatirwa. Kuedza kwakaitwa kuvakadzi vane makore anopfuura makumi mashanu kwakaratidza kuti kunwa squalene kunogona kuderedza zvakanyanya makwinya echiso uye kunatsiridza mapundu echiso uye pigmentation. Pamusoro pezvo, squalene inogona kuwedzera basa re enzymes ye antioxidant yeganda, uye mhedzisiro yacho iri nani kupfuura vhitamini E. Nekuda kwemhedzisiro yayo yakanaka yekunyorovesa, mamwe mabrandi anozivikanwa ekushongedza akaishandisa muzvigadzirwa zvekuchengetedza ganda nebvudzi zvakaita se hydrating serums uye mafuta ekuchengetedza ganda.

3. Kushandiswa kweSqualene muindasitiri

1). Squalene nezvimwe zvigadzirwa zvayo zvine hydrogen zvakakurumbira nekuda kwekushandiswa kwazvinoita muzvizoro. Squalene ine mabhenefiti akawanda pahutano hweganda, kusanganisira dziviriro kubva kumwaranzi yeUV uye antioxidant. Inovandudza magadzirirwo eganda, inoderedza maburi nemakwinya, uye inonyorovesa ganda pasina kukonzera kushatirwa.

2). Semafuta echisikigo, squalene inoshandiswa zvakanyanya semushonga unoshanda mumuviri kuti mushonga uburitswe kwenguva refu. Mishonga yeEmulsion ine squalene inogona kuwedzera hafu yehupenyu hwemushonga.

3). Squalene yakaratidza mikana yakawanda yekushandisa mukutsvaga kwekurapa: mumasero eHepG2, inoongorora mashandiro ekuderedza cholesterol nekudzivisa kuwanda kwemasero uye kuwedzera LDLR; chechipiri, zvidzidzo zvemamorekuru zvinoratidza kuti squalene inogona kunge iine basa mukurapa kenza yeganda; pakupedzisira, nekuiswa muPLGA NPs, kushanda zvakanaka kwemafuta emuorivhi mumasero kunovandudzwa, uye ine mukana wekuchengetedza hutano hwemasero uye kudzivirira kushushikana kwe oxidative.

4). Sechikafu chinobatsira, squalene yakakwezva vanhu vakawanda uye yakadzidzwa zvakanyanya nezvebasa rayo mukudzivirira zvirwere zvemwoyo, kenza nezvimwe zvirwere.

Ndekupi Kwekutenga Squalene?

Zvinhu Zvikuru Pakusarudza Mutengesi weSqualene

1. Hunhu hwechigadzirwa

Pakusarudza mutengesi, chinhu chekutanga chekufunga nezvacho imhando yechigadzirwa. Hupfu hweSqualene hwakachena kwazvo hunovimbisa kushanda kwayo uye kushanda kwayo. Hupfu hweSqualene hwakapihwa naSuzhou Myland hwakaongororwa zvakanyanya kuti huve nechokwadi chekuti chigadzirwa chega chega chinosangana nezvinodiwa zvepasi rose uye chine mhando yakavimbiswa.

2. Kugona kugadzira

Kugona kwemugadziri kugadzira zvinhu kunokanganisa zvakananga nguva uye kugadzikana kwekuwanikwa kwezvinhu. Suzhou Myland ine michina yekugadzira zvinhu yepamusoro uye tekinoroji inogona kusangana nezvinodiwa zvekugadzirwa kwezvinhu zvakawanda, zvichiita kuti vatengi vawane zvigadzirwa zvavanoda nenguva pavanenge vachizvida.

3. Kugona kweR&D

Mutengesi akanaka kwazvo anowanzova nechikwata chakasimba cheR&D chinogona kuramba chichivandudza zvigadzirwa nekugadzira zvigadzirwa zvitsva. Suzhou Myland ine ruzivo rwakakura mukutsvaga nekushandisa Squalene uye inokwanisa kupa vatengi rutsigiro rwehunyanzvi uye mhinduro.

4. Basa reVatengi

Kushandira vatengi zvakanaka chinhu chisingafanirwe kufuratirwa pakusarudza mutengesi. Suzhou Myland inotarisa pakutaurirana nevatengi uye inokwanisa kupa masevhisi akagadzirirwa vatengi zvichienderana nezvinodiwa nevatengi kuitira kuti vatengi vawane ruzivo rwakanakisisa panguva yekutenga.

5. Chitupa uye Kutevedzera Mutemo

Kuve nechokwadi chekuti vatengesi vane zvitupa zvakakodzera uye kutevedzera mitemo ndizvo zvinhu zvakakosha pakusarudza. Suzhou Myland ine chitupa cheISO uye inotevedzera mitemo yeGMP (Good Manufacturing Practice), ichiva nechokwadi chekuti zvigadzirwa zvayo zvinotevedzera hurongwa hwakasimba hwekutarisira mhando panguva yekugadzira.

Mukupedzisa

Kusarudza mutengesi akakodzera weSqualene kwakakosha pakuona kuti chigadzirwa chacho chakanaka uye chakachengeteka. Suzhou Myland yave sarudzo yakavimbika muindasitiri iyi nekuda kwezvigadzirwa zvayo zvakachena, kudzora mhando zvakanyanya uye masevhisi ehunyanzvi. Ungave uri mugadziri wezvigadzirwa zvekuchengetedza ganda, kambani yezvizoro kana mumwe munhu anoda indasitiri iyi, Suzhou Myland inogona kukupa upfu hweSqualene hwemhando yepamusoro kuti ikubatsire pahutano hwako nekukura kwebasa. Kuti uwane rumwe ruzivo, ndapota shanyira webhusaiti yepamutemo yeSuzhou Mailun Biology.