Chii chinonzi Salidroside uye Chingakubatsira Sei?

Salidroside inozivikanwawo se (4-hydroxy-phenyl)-β-D-glucopyranoside, inozivikanwawo se salidroside uye rhodiola extract. Inogona kubviswa kubva kuRhodiola rosea kana kugadzirwa nemaoko. Salidroside iantioxidant yechisikigo inodzivirira masero etsinga nekubvisa ROS uye kudzivirira apoptosis yemasero.

Rhodiola rosea chirimwa chinomera kwenguva refu chinokura munzvimbo dzine kutonhora kwakanyanya, kuoma, anoxia, mwaranzi ye ultraviolet yakasimba, uye musiyano mukuru wekupisa masikati neusiku pakukwirira kwemamita 1,600 kusvika 4,000. Chine simba guru uye chinochinjika nharaunda.

Salidroside--Antioxidant

Salidroside iantioxidant yechisikigo inogona kubvisa reactive oxygen species (ROS), kudzivirira apoptosis, uye kudzivirira masero etsinga. Inogona kuvandudza kugona kwekudzivirira antioxidant yeganda nekushandisa masisitimu e intracellular antioxidant enzymes, akadai se superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), nezvimwewo.

Kuwanda kwecalcium mumuviri ndicho chimwe chezvinhu zvikuru zvinokonzera apoptosis yemasero etsinga. Rhodiola rosea extract uye salidroside zvinogona kuderedza kuwedzera kwemazinga ecalcium akasununguka mukati memasero anokonzerwa nekushushikana kwe oxidative uye kudzivirira masero e cortical evanhu kubva ku glutamate. uye hydrogen peroxide-induced apoptosis. Salidroside inogona kudzivirira lipopolysaccharide-induced microglial activation, kudzivirira kugadzirwa kweNO, kudzivirira inducible nitric oxide synthase (iNOS) activity, uye kuderedza TNF-α uye IL-1β. , IL-6 levels.

Salidroside inodzivirira NADPH oxidase 2/ROS/mitogen-activated protein kinase (MAPK) uye response regulator of development uye DNA damage 1 (REDD1)/mammalian target ye rapamycin (mTOR)/p70 ribosome. Nzira yeprotein S6 kinase signaling pathway inomutsa AMP-dependent protein kinase/silent information regulator 1, RAS homologous gene family member A/MAPK uye PI3K/Akt signaling pathways.

Mabhenefiti eSalidroside

1. Kudzora muviri nenzira mbiri: Rhodiola rosea inobatanidza zvinhu zvakanaka mumuviri uye ine nzira mbiri dzekugadzirisa muviri dzekugadzirisa kusakwana uye kuderedza kuwanda kwemuviri. Nekudzora mashandiro etsinga, endocrine system uye metabolic system, shuga yeropa, mafuta eropa, BP uye mashandiro emwoyo netsinga dzeropa zvinogona kudzorerwa padanho rakajairika.

2. Kudzora tsinga zvinobudirira: kubvisa kushushikana kwevanhu zvinobudirira, kudzikamisa tsinga huru, kunatsiridza hope nekutsamwa, kufara kana kuora mwoyo; kunatsiridza kutarisisa uye kunatsiridza ndangariro. Kuzorodza uropi, kuderedza zvikanganiso, kunatsiridza kushanda zvakanaka kwebasa nekudzidza, uye kudzivirira chirwere cheAlzheimer.

3. Kudzivirira kuneta: Rhodiola rosea ine simba rekurwisa marwadzo emwoyo, izvo zvinogona kuwedzera nguva yekushanda kweuropi nemuviri uye kuwedzera simba remitsipa yeuropi netsandanyama dzemuviri. Ine simba guru pakudzivirira nekurapa chirwere chekuneta uye kuchengetedza simba rakasimba uye simba kwenguva yakareba.

4. Kurwisa mwaranzi uye kurwisa bundu: Salidroside inogona kuwedzera zvinobudirira mwero wekushanduka kweT lymphocytes uye mashandiro ephagocytes, kuwedzera dziviriro yemuviri, kudzivirira kukura kwebundu, kuwedzera masero machena eropa, kurwisa mwaranzi ye microwave, uye kurapa varwere vegomarara mushure me radiotherapy nezvimwe. Ine mhedzisiro yakanaka kwazvo yekubatsira pakugadzirisa kune avo vasina simba mumuviri mushure mekurwara.

5. Kudzivirira hypoxia: Rhodiola rosea inogona kuderedza mwero wekushandiswa kweokisijeni mumuviri, kuvandudza kushivirira kweuropi hypoxia, uye panguva imwe chete inowedzera kugona kweropa kutakura okisijeni, kuwedzera kudzivirira kwemuviri kuzvirwere, uye kukurumidza kupora matishu ane chirwere.

6. Mhedzisiro pamhasuru dzakatsetseka dzemunhu: Asthma inokonzerwa nekukweshana kwemhasuru dzakatsetseka. Rhodiola rosea inogona kubatsira zvikuru kuderedza kukweshana kwemhasuru dzakatsetseka uye kudzora kufamba kwemhasuru dzakatsetseka dzemudumbu. Inobatsira zviri pachena paasthma, bronchitis, phlegm, kuvimbiwa, nezvimwewo.

7. Mhedzisiro pa rheumatoid arthritis: Arthritis inokonzerwa nezvakaipa zvitatu zvemhepo, kutonhora, uye hunyoro. Kuongororwa kwakawanda kwekiriniki kwakaratidza kuti Rhodiola rosea inogona kudzinga mhepo, kurwisa kutonhora, uye kubvisa marwadzo. Inonyanya kuve nemigumisiro yakajeka pakuzvimba kwemajoini. Kuzvimba uye kudzivirira.

8. Kudzivirira kukwegura: Rhodiola rosea inogona kunonotsa kukwegura kwemasero, kuwedzera kushanda kweSOD mumuviri, uye kudzivirira kuumbwa kwe lipofuscin mukati memasero uye mhando dzeokisijeni dzinoshanda. Inovandudza metabolism yemasero uye kugadzirwa kwayo uye inovandudza simba remasero. Pamusoro pezvo, inewo runako uye mhedzisiro yekuchengetedza ganda.

Munda weSalidroside & Ganda rekuchengetedza

Mukuchengetedza ganda, salidroside inogona kuramba kukuvara kwe ultraviolet uye kubvisa ma free radicals anokonzerwa ne mitochondria. Mabasa ayo e antioxidant uye anti-inflammatory anogona kuvandudza mamiriro eganda, kuderedza makwinya, uye kuita kuti ganda ritaridzike sediki.

Rhodiola rosea inogona kuderedza kushanda kweacid phosphatase uye zvigadzirwa zvekupedzisira zvekuora kwelipid peroxide (LPO) nekuwedzera kushanda kwema enzymes ane chekuita neantioxidant (SOD superoxide dismutase, GSH-Px glutathione peroxidase neCAT) uye huwandu hweMDA, nokudaro ichivandudza kugona kwemuviri kubvisa ma free radicals, kuderedza mwero we peroxidation ye biofilms, uye kudzivirira masero nematishu emuviri kubva mukukuvadzwa kwe free radicals.

Dzivisa kutora mifananidzo yeganda

Salidroside inogona kuderedza kuparara kwe extracellular matrix senge collagen uye kukurudzira kukura kwe fibroblasts, nokudaro ichisimudzira kusimba kweganda, inononotsa kuitika kwemakwinya eganda, uye kuzadzisa chinangwa chekudzivisa kupenya kweganda.

Kuchenesa

Salidroside inogona kuderedza kugadzirwa kwe melanin nekudzivisa kushanda kwe tyrosinase. Tyrosinase ndiyo enzyme huru yekugadzira melanin. Salidroside inogona kubatana ne tyrosinase uye kuderedza kushanda kwayo, nokudaro ichideredza kugadzirwa kwe melanin.

Salidroside inogonawo kudzivirira kugadzirwa kwemelanin nekutonga nzira dzekutumira mameseji muma melanocytes, senge nzira yekutumira mameseji yeMITF. MITF chinhu chakakosha mukunyora kwemashoko muma melanocytes, icho chinodzora kuburitswa kwema enzymes ane chekuita nekugadzirwa kwemelanin akadai se tyrosinase. Salidroside inogona kuderedza kuburitswa kweMITF, nokudaro ichideredza kugadzirwa kwemelanin.

Anti-kuzvimba

Salidroside inogona kuderedza kuzvimba kunokonzerwa nemwaranzi ye ultraviolet, kugadzirisa masero eganda akakuvara, uye kukurudzira kugadzikiswa kweganda uye kugadziriswa kwaro.

Mamiriro aripo pari zvino ekugadzirwa kwesalidroside

1) Kunyanya kuvimba nekubviswa kwezvirimwa

Rhodiola rosea imhando yesalidroside. Semhando yemiti inogara kwenguva refu inomera, Rhodiola rosea inonyanya kukura munzvimbo dzine kutonhora kwakanyanya, anoxia, kuoma uye musiyano mukuru wekupisa pakati pemasikati neusiku pakukwirira kwemamita 1600-4000. Ndiyo imwe yemiti yemusango. China ndeimwe yenzvimbo huru dzinogadzira Rhodiola rosea pasi rose, asi mararamiro eRhodiola rosea akasiyana zvikuru. Hazvisi zvakaoma kurima nekugadzira chete, asi goho remhando dzemusango rakaderera zvikuru. Parizvino, musiyano wegore negore weRhodiola rosea wakakwira kusvika matani 2,200.

2) Kugadzirwa kwemakemikari uye kuviriswa kwezvipenyu

Nekuda kwehuwandu hwakaderera uye mutengo wakakwira wekugadzira muzvirimwa, kuwedzera kune nzira dzekugadzira dzechisikigo, nzira dzekugadzira salidroside dzinosanganisirawo nzira dzekugadzira makemikari, nzira dzekuvirisa zvipenyu, nezvimwewo. Pakati padzo, sezvo tekinoroji iri kuramba ichikura, kuvirisa zvipenyu kwave nzira huru yehunyanzvi hwekutsvaga nekuvandudza nekugadzira salidroside. Parizvino, Suzhou Mailun yawana mhedzisiro yekutsvaga nekusimudzira uye yakawana maindasitiri.

Kushandiswa kwemwaranzi chikamu chisingadzivisiki muhupenyu hwedu hwezuva nezuva uye chinowanzoshandiswa mukuongorora nekurapa kwechiremba. Zvisinei, kukuvara kunokonzerwa nemwaranzi kumatishu nemasero evanhu hakugoni kufuratirwa. Nokudaro, kuwana mishonga inodzivirira mwaranzi inoshanda, isina chepfu shoma kana kuti isina chepfu kwagara kuri chinhu chinonyanya kufarirwa pakutsvakurudza.

Suzhou Myland Nutraceuticals Inc. ikambani yakanyoreswa neFDA inopa hupfu hweSalidroside hwemhando yepamusoro uye hwakachena.

KuSuzhou Myland takazvipira kupa zvigadzirwa zvemhando yepamusoro nemitengo yepamusoro. Upfu hwedu hweSalidroside hwakaedzwa zvakasimba kuti huve hwakachena uye hune simba, zvichiita kuti uwane chinowedzera chemhando yepamusoro chaunogona kuvimba nacho. Kunyangwe uchida kutsigira hutano hwemasero, kusimbisa masoja emuviri wako kana kusimudzira hutano hwese, upfu hwedu hweSalidroside ndiyo sarudzo yakakwana.

Nemakore makumi matatu eruzivo uye zvichitungamirirwa netekinoroji yepamusoro uye nzira dzeR&D dzakanyatsogadzirwa, Suzhou Myland yakagadzira zvigadzirwa zvakasiyana-siyana zvinokwikwidzana uye yakava kambani itsva yekuwedzera sainzi yehupenyu, kugadzira zvinhu zvakagadzirwa nemaoko uye kugadzira zvinhu.

Pamusoro pezvo, Suzhou Myland ikambani yakanyoreswa neFDA. Zvishandiso zveR&D zvekambani, nzvimbo dzekugadzira, uye zvishandiso zvekuongorora ndezvemazuva ano uye zvinoshanda zvakawanda, uye zvinogona kugadzira makemikari kubva pamamirigiramu kusvika kumatani muhukuru, uye zvinoenderana neISO 9001 standards uye specifications dzekugadzira GMP.