Salidroside inozivikanwawo se (4-hydroxy-phenyl) -β-D-glucopyranoside, inozivikanwawo se salidroside uye rhodiola extract. Inogona kutorwa kubva kuRhodiola rosea kana kuti yakagadzirwa nemaoko. Salidroside ndeye yakasikwa antioxidant inodzivirira masero etsinga nekutsvaira ROS uye inhibiting cell apoptosis.
Rhodiola rosea chirimwa cheperennial herbaceous chinokura zvakanyanya munzvimbo dzine kutonhora kwakanyanya, kuoma, anoxia, yakasimba ultraviolet mwaranzi, uye hukuru hwetembiricha musiyano pakati pemasikati nehusiku pahupamhi hwemamita 1,600 kusvika 4,000. Iyo ine yakasimba zvakanyanya kuchinjika kwezvakatipoteredza uye simba.
Salidroside - Antioxidant
Salidroside ndeye yakasikwa antioxidant iyo inogona kutsvaira reactive oxygen marudzi (ROS), inhibit apoptosis, uye kudzivirira masero etsinga. Inogona kuvandudza ganda rinodzivirira antioxidant nekuita intracellular antioxidant enzyme masisitimu, senge superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), nezvimwe.
Intracellular calcium overload ndechimwe chezvikonzero zvikuru zve neuronal apoptosis. Rhodiola rosea inobvisa uye salidroside inogona kuderedza kuwedzera kwe intracellular yemahara calcium mazinga anokonzerwa neoxidative kusagadzikana uye kudzivirira masero ecortical evanhu kubva ku glutamate. uye hydrogen peroxide-induced apoptosis. Salidroside inogona kudzivisa lipopolysaccharide-induced microglial activation, inhibit NO kugadzirwa, inhibit inducible nitric oxide synthase (iNOS) basa, uye kuderedza TNF-α uye IL-1β. , IL-6 mazinga.
Salidroside inhibits NADPH oxidase 2/ROS/mitogen-activated protein kinase (MAPK) uye mhinduro regulator yekuvandudza uye DNA kukuvara 1 (REDD1)/mammalian target ye rapamycin (mTOR)/p70 ribosome Iprotein S6 kinase inoratidzira nzira inoshandisa AMP-inotsamira. protein kinase / silent information regulator 1, RAS homologous gene nhengo yemhuri A/MAPK uye PI3K/Akt kusaina nzira.
Mabhenefiti eSalidroside
1. Maitiro maviri ekugadzirisa maitiro: Rhodiola rosea inounganidza zvinhu zvose zvakanaka mumuviri uye ine nzira mbiri dzekugadzirisa maitiro ekugadzirisa kukanganisa uye kuderedza kuwandisa. Nekugadzirisa mashandiro ehurongwa hwetsinga, endocrine system uye metabolic system, shuga yeropa, lipids yeropa, BP uye yemwoyo uye cerebrovascular mabasa anogona kudzoserwa kune akajairwa mazinga.
2. Kugadziriswa kunobudirira kwehutano hwemagetsi: kunyatsobvisa kushushikana kwevanhu, kuenzanisa pakati penheyo system, kuvandudza kurara uye kutsamwa, kufara kana kuora mwoyo; kunatsiridza kutarisisa uye kuwedzera ndangariro. Zorora huropi, kuderedza mhosho, kunatsiridza basa uye kugona kudzidza, uye kudzivirira chirwere cheAlzheimer.
3. Anti-kuneta: Rhodiola rosea ine cardiotonic effect, iyo inogona kuwedzera nguva yenguva dzose yezviitwa zvehuropi nemuviri uye kuwedzera simba remutoro weuropi tsinga uye mhasuru dzemuviri. Iine zvakakosha pakudzivirira nekurapa kuneta kwechirwere uye kuchengetedza simba rakasimba uye simba kwenguva yakareba.
4. Anti-radiation uye anti-bundu: Salidroside inogona kunyatso wedzera shanduko yeT lymphocytes uye basa re phagocytes, kusimudzira hutachiona, kurambidza bundu kukura, kuwedzera masero machena eropa, kurwisa microwave mwaranzi, uye kurapa cancer varwere mushure meradiotherapy nezvimwe. Iine yakanaka kwazvo yekubatsira kudzorera maitiro kune avo vasina kusimba mumuviri mushure mekurwara.
5. Anti-hypoxia: Rhodiola rosea inogona kuderedza kushandiswa kweokisijeni yose mumuviri, kunatsiridza kushivirira kweuropi ku hypoxia, uye panguva imwe cheteyo kuwedzera simba rokutakura okisijeni yeropa, kuwedzera kurwisa hosha yomuviri, uye nokukurumidza kupora matishu ane chirwere. .
6. Mhedzisiro pamhasuru yemunhu yakatsetseka: Asthma inokonzerwa nekutsetseka kwetsandanyama. Rhodiola rosea inogona kunyatso bvisa yakatsetseka tsandanyama spasm uye kugadzirisa intestinal yakatsetseka tsandanyama kufamba. Iine mhedzisiro yakajeka paasthma, bronchitis, phlegm, kuvimbiswa, nezvimwe.
7. Mhedzisiro parheumatoid arthritis: Arthritis inokonzerwa nouipi hutatu hwemhepo, kutonhora, uye unyoro. Nhamba huru yemakiriniki miedzo yakaratidza kuti Rhodiola rosea inogona kudzinga mhepo, kuramba kutonhora, uye kubvisa marwadzo. Iyo inonyanya kuve nemhedzisiro yakajeka pakuzvimba kwemajoini. Kuzvimba uye inhibitory effect.
8. Anti-kuchembera: Rhodiola rosea inogona kunonoka kuchembera kwesero, kuwedzera basa reSOD mumuviri, uye kudzivisa kuumbwa kwe intracellular lipofuscin uye reactive oxygen marudzi. Wedzera cell metabolism uye synthesis uye inovandudza cell vitality. Mukuwedzera, inewo runako uye ganda rekuchengetedza migumisiro.
Salidroside & Skin Care Field
Mumunda wekuchengetwa kweganda, salidroside inogona kuramba kukuvara kwe ultraviolet uye kubvisa mahara radicals anogadzirwa nemitochondria. Iyo antioxidant uye anti-kuzvimba mhedzisiro inogona kuvandudza mamiriro eganda, kuderedza kuunyana, uye kuita kuti ganda ritaridzike diki.
Rhodiola rosea inogona kuderedza asidi phosphatase chiitiko uye yekupedzisira kuora zvigadzirwa zve lipid peroxide (LPO) nekuwedzera basa re antioxidant-related enzymes (SOD superoxide dismutase, GSH-Px glutathione peroxidase uye CAT) zvirimo uye MDA zvirimo, nekudaro zvichiwedzera kugona kwemuviri. kuchenesa mahara radicals, kuderedza dhigirii yeperoxidation yebiofilms, uye kuchengetedza masero emuviri uye matishu kubva mahara radical kukuvara.
Kudzivirira ganda photoaging
Salidroside inogona kuderedza kuderedzwa kweiyo extracellular matrix senge collagen uye kusimudzira kukura kwefibroblasts, nekudaro ichiwedzera elasticity yeganda, kunonoka kuitika kweganda wrinkles, uye kuzadzisa chinangwa chekuramba photoaging.
Whitening
Salidroside inogona kuderedza melanin synthesis nekudzivisa tyrosinase basa. Tyrosinase ndiyo yakakosha enzyme ye melanin synthesis. Salidroside inogona kusunga kune tyrosinase uye kuderedza basa rayo, nokudaro kuderedza kugadzirwa kwe melanin.
Salidroside inogonawo kuvharidzira melanin synthesis nekugadzirisa nzira dzekusaina mumamelanocytes, senge MITF yekusaina nzira. MITF chinhu chakakosha chekunyora mu melanocytes, iyo inodzora kutaura kwe melanin synthesis-ane hukama enzymes senge tyrosinase. Salidroside inogona kuderedza kutaura kweMITF, nekudaro kuderedza melanin synthesis.
Anti-inflammatory
Salidroside inogona kuderedza mhinduro yekuzvimba inokonzerwa nemirairo yeultraviolet, kugadzirisa masero eganda akakuvadzwa, uye kukurudzira kuvandudzwa kweganda uye kugadzirisa.
Ikozvino mamiriro ekugadzirwa kwesalidroside
1) Kunyanya kuvimba nekuchera chirimwa
Rhodiola rosea ndiyo mbishi ye salidroside. Serudzi rweperennial herbaceous chirimwa, Rhodiola rosea inokura zvakanyanya munzvimbo dzine kutonhora kwakanyanya, anoxia, kuoma uye musiyano mukuru wekushisa pakati pemasikati nehusiku pahupamhi hwemamita 1600-4000. Ndechimwe chemiti yemusango. China ndiyo imwe yenzvimbo huru dzekugadzira Rhodiola rosea munyika, asi mararamiro eRhodiola rosea akanyanya kukosha. Hazvisi chete zvakaoma kurima zvekugadzira, asi goho remhando dzesango rakaderera zvakanyanya. Parizvino, gap rekuda kwegore reRhodiola rosea rakakwira se2,200 matani.
2) Chemical synthesis uye biological fermentation
Nekuda kwekushomeka kwemukati uye mutengo wakakwira wekugadzira muzvirimwa, kunze kwenzira dzechisikigo dzekuchera, nzira dzekugadzira salidroside dzinosanganisira nzira dzemakemikari synthesis, biological fermentation nzira, nezvimwe. Pakati pazvo, sezvo tekinoroji ichiramba ichikura, biological fermentation yave inonyanya kufarirwa. tekinoroji nzira yekutsvagisa nekusimudzira uye kugadzirwa kwesalidroside. Parizvino, Suzhou Mailun yakawana tsvakiridzo nebudiriro mhedzisiro uye yakawana maindasitiri.
Radiation chikamu chisingadzivisiki chehupenyu hwedu hwezuva nezuva uye inowanzoshandiswa mukuongororwa kwechiremba uye kurapwa. Nekudaro, kukuvadzwa kunokonzerwa nemwaranzi kumatishu emunhu uye masero hakugone kufuratirwa. Naizvozvo, kuwana inoshanda, yakaderera-chepfu kana isina-chepfu inodzivirira radiation yakagara iri hotspot yekutsvaga.
Suzhou Myland Nutraceuticals Inc. ndeye FDA-yakanyoreswa mugadziri inopa yepamusoro-mhando uye yakakwirira-kuchena Salidroside poda.
KuSuzhou Myland takazvipira kupa zvigadzirwa zvemhando yepamusoro nemitengo yakanakisa. Yedu Salidroside poda yakaedzwa zvakasimba kuchena uye potency, kuve nechokwadi kuti iwe unowana yemhando yepamusoro yekuwedzera iwe yaunogona kuvimba nayo. Kunyangwe iwe uchida kutsigira hutano hweserura, kuwedzera immune system yako kana kuwedzera hutano hwese, yedu Salidroside poda ndiyo sarudzo yakakwana.
Iine makore makumi matatu echiitiko uye ichisundwa nehunyanzvi hwepamusoro uye akakwenenzverwa zvakanyanya eR&D mazano, Suzhou Myland yakagadzira mhando yezvigadzirwa zvemakwikwi uye ive yekuvandudza hupenyu hwesainzi yekuwedzera, yetsika synthesis uye yekugadzira masevhisi kambani.
Uye zvakare, Suzhou Myland zvakare iri FDA-yakanyoreswa mugadziri. Zviwanikwa zvekambani zveR&D, zvivakwa zvekugadzira, uye zviridzwa zvekuongorora ndezvemazuva ano uye zvinoshanda, uye zvinogona kugadzira makemikari kubva kumamirigiramu kusvika kumatani muchiyero, uye zvinoenderana neISO 9001 zviyero uye kugadzirwa kweGMP.
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Nguva yekutumira: Oct-09-2024