Chii chinonzi Beta-Hydroxybutyrate (BHB) uye Hezvino Zvaunofanira Kuziva

Beta-hydroxybutyrate (BHB) ndeimwe yemiviri mikuru mitatu yeketone inogadzirwa nechiropa panguva yekudya makabhohaidhiretsi mashoma, kutsanya, kana kurovedza muviri kwenguva refu. Mimwe miviri yeketone iacetoacetate neacetone. BHB ndiyo ketone inowanikwa zvakanyanya uye inoshanda, zvichiita kuti iite basa rakakosha mukushandiswa kwesimba mumuviri, kunyanya kana shuga iri shoma. Beta-hydroxybutyrate (BHB) iketone ine simba inoita basa rakakosha mukushandiswa kwesimba mumuviri, kunyanya panguva yeketosis. Mabhenefiti ayo anopfuura kugadzirwa kwesimba kuti ape mabhenefiti ekuziva, kudzora uremu, uye ekudzivirira kuzvimba. Ungave uchitevera kudya kweketogenic kana kutsvaga kuvandudza hutano hwako hwemetabolism, zvakakosha kunzwisisa BHB nemabasa ayo.

Chii chinonzi beta-hydroxybutyrate (BHB)?

Beta-hydroxybutyrate (BHB) ndeimwe yemiviri mitatu yeketone inogadzirwa nechiropa kana paine kushomeka kwemacarbohydrate. (Inozivikanwawo se3-hydroxybutyrate kana 3-hydroxybutyric acid kana 3HB.)

Heino pfupiso yemiviri yeketone inokwanisa kugadzirwa nechiropa:

Beta-Hydroxybutyrate (BHB). Iyi ndiyo ketone yakawanda mumuviri, inowanzoita 78% yemaketone muropa. BHB ndiyo mhedzisiro ye ketosis.

Acetoacetate. Rudzi urwu rweketone runoumba inenge 20% yeketone bodies muropa. BHB inogadzirwa kubva kuacetoacetate uye haigone kugadzirwa nemuviri neimwe nzira. Zvakakosha kuziva kuti acetoacetate haina kugadzikana seBHB, saka acetoacetate inogona kushanduka yoga kuita acetone isati yatanga kuita reaction inoshandura acetoacetate kuita BHB.

acetone. Maketone mashoma kwazvo; anoumba anenge 2% emaketone muropa. Haashandiswi sesimba uye anoburitswa mumuviri nekukasika.

BHB neacetone zvinobva muacetoacetate, zvisinei, BHB ndiyo ketone huru inoshandiswa pakupa simba nekuti inogara kwenguva refu uye yakawanda, nepo acetone ichirasika kuburikidza nekufema nekudikitira.

Zvese zvaunoda kuziva nezveBHB

Munguva ye ketosis, mhando nhatu huru dze ketone bodies dzinogona kuonekwa muropa:

●acetoacetate

●β-Hydroxybutyrate (BHB)

●Acetone

BHB ndiyo ketone inoshanda zvakanyanya, inoshanda zvakanyanya kupfuura glucose. Haingopi simba rakawanda kupfuura shuga chete, asi inorwisawo kukuvara kwe oxidative, inoderedza kuzvimba, uye inovandudza mashandiro enhengo dzemuviri, kunyanya uropi.

Kana uchida kuderedza uremu, kuvandudza mashandiro epfungwa, uye kuwedzera hupenyu hwako, BHB ndiyo sarudzo yako yakanakisa.

Nzira iri nyore yekuwedzera mazinga eBHB ndeyekutora ma ketones ekunze uye mafuta eMCT. Zvisinei, izvi zvinovaka muviri zvinongowedzera mazinga e ketone kusvika muviri wako waashandisa.

Kuti ukurudzire kugadzirwa kweBHB kwenguva refu nenzira ine hutano, unofanirwa kutevedzera ketogenic diet.

Paunenge uchidya chikafu ichi, unogona kushandisa nzira dzakasiyana siyana dzekuwedzera kugadzirwa kweketones, kusanganisira:

●Deredza kudya makabhohaidhiretsi kusvika pasi pe15 magiramu pazuva kwevhiki yekutanga.

●Kuderedza huwandu hweglycogen muropa kuburikidza nekurovedza muviri kwakasimba.

●Ita maekisesaizi akasimba zvishoma kusvika pakati nepakati kuti uwedzere kupisa mafuta uye kugadzirwa kweketone.

●Tevedzera hurongwa hwekutsanya nguva nenguva.

Kana uchida kuwedzerwa simba, tora MCT Oil supplement uye/kana BHB Keto Salts

Sei muviri wako uchida BHB? kubva pamaonero ekushanduka-shanduka kwezvinhu

Muviri wako haunzwi here sekuti uri kuedza zvakanyanya kugadzira nekushandisa ma ketones mashoma? Haupisi mafuta here? Ehe, kwete.

Mafuta acid anogona kushandiswa semafuta kumasero mazhinji, asi kuuropi, anononoka zvakanyanya. Uropi hunoda simba rinoshanda nekukurumidza, kwete mafuta anononoka kugaya semafuta.

Nekuda kweizvozvo, chiropa chakagadzira kugona kushandura mafuta acids kuita ketone bodies—simba rinobva muuropi kana shuga isina kukwana. Imi nyanzvi dzesainzi mungave muchifunga kuti: "Hatigone kushandisa gluconeogenesis kupa shuga kuuropi here?"

Ehe, tinogona—asi kana makabhohaidhiretsi ari mashoma, tinofanira kugaya tsandanyama dzinenge 200 gramu (anenge mapaundi 0.5) pazuva todzishandura kuita shuga kuti dzipe simba kuuropi hwedu.

Nekupisa ma ketone semafuta, tinochengetedza tsandanyama, tinopa zvinovaka muviri kuuropi, uye tinowedzera hupenyu kana chikafu chishoma. Kutaura zvazviri, ketosis inogona kubatsira kuderedza kurasikirwa kwemuviri usina mafuta panguva yekutsanya nekashanu.

Nemamwe mashoko, kushandisa ma ketone semafuta kunoderedza kuda kwedu kupisa tsandanyama kubva pamagiramu mazana maviri kusvika makumi mana pazuva kana chikafu chishoma. Zvisinei, kana ukatevera ketogenic diet kuti uderedze huremu, uchatorasikirwa nemagiramu asingasviki makumi mana etsandanyama pazuva nekuti unenge uchipa muviri wako zvinovaka muviri zvinochengetedza tsandanyama zvakaita seprotein.

Kwemavhiki kusvika kumwedzi yakawanda yekudya ketosis (kana huwandu hweketones dzako huri pakati pe0.5 ne3 mmol/L), ketones dzinosvika 50% yesimba rako rekutanga uye 70% yesimba rako reuropi. Izvi zvinoreva kuti ucharamba uine tsandanyama dzakawanda uku uchiwana mabhenefiti ese ekupisa ketone:

Kuvandudza mashandiro ekuziva uye kujekesa pfungwa

●Shuga yeropa inogara yakagadzikana

● Simba rakawanda

●Kurasikirwa nemafuta nguva dzose

●Kuita zvakanaka kwemitambo

Sei muviri wako uchida BHB? kubva pakuona kwemuchina

BHB haingotibatsiri chete kudzivirira kupera simba kwetsandanyama, asi inopawo mafuta zvinobudirira kupfuura shuga munzira mbiri:

●Inogadzira ma free radicals mashoma.

●Zvinotipa simba rakawanda pamorekuru imwe neimwe.

Kugadzirwa Kwesimba uye Madhiragi Akasununguka: Glucose (Shuga) vs. BHB

Patinogadzira simba, tinogadzira zvinhu zvinokuvadza zvinonzi free radicals (kana kuti oxidants). Kana zvinhu izvi zvikaungana nekufamba kwenguva, zvinogona kukanganisa masero neDNA.

Munguva yekugadzira ATP, okisijeni nehydrogen peroxide zvinobuda. Izvi zvinobuda mafree radicals, zvinogona kurwiswa zviri nyore ne antioxidants.

Zvisinei, vane mukana wekuti vasadzorerwe voshanduka kuita mafree radicals anokuvadza zvakanyanya (kureva, reactive nitrogen species uye hydroxyl radicals), ayo anokonzera kukuvara kukuru kweoxidative mumuviri.

Saka, kuti tive nehutano hwakanaka, kuunganidzwa kwenguva refu kwemafree radicals kunofanira kuderedzwa. Kuti tiite izvi, tinofanira kushandisa simba rakachena pese pazvinogoneka.

Kugadzirwa kweglucose uye free radicals

Glucose inofanira kupfuura nemaitiro akarebesa zvishoma kupfuura BHB isati yapinda muKrebs cycle kuti igadzire ATP. Kana maitiro acho apera, mamorekuru mana eNADH achagadzirwa uye chiyero cheNAD+/NADH chichaderera.

NAD+ neNADH zvinokosha nekuti zvinodzora mashandiro e oxidant ne antioxidant:

●NAD+ inodzivirira kushushikana kwe oxidative, kunyanya matambudziko anokonzerwa nechimwe chezvinokonzera oxidative zvambotaurwa: hydrogen peroxide. Inowedzerawo autophagy (maitiro ekuchenesa nekuvandudza zvikamu zvemasero zvakakuvara). Pasi pekushanda kwemaitiro akasiyana-siyana e metabolic, NAD+ inova NADH, iyo inoshanda se electron shuttle yekugadzira simba.

●NADH inodiwawo nekuti inopa maerekitironi ekugadzira ATP. Zvisinei, haidziviriri kubva mukukuvadzwa kwemafree radicals. Kana paine NADH yakawanda kupfuura NAD+, mafree radicals akawanda anogadzirwa uye maenzymes anodzivirira anodziviswa.

Nemamwe mashoko, kazhinji, chiyero cheNAD+/NADH chinofanirwa kuchengetwa chakakwirira. Mazinga eNAD+ akaderera anogona kukonzera kukuvara kwakanyanya kwemasero.

Sezvo glucose metabolism ichidya mamorekuru mana eNAD+, huwandu hweNADH huchava hwakawanda, uye NADH inokonzera kukuvara kwakanyanya kwe oxidative. Muchidimbu: Glucose haitsvi zvachose—kunyanya kana ichienzaniswa neBHB.

BHB uye kugadzirwa kwemahara radicals

BHB haifambiswe neglycolysis. Inongochinja kuita acetyl-CoA isati yapinda muKrebs cycle. Kazhinji, maitiro aya anongoshandisa mamorekuru maviri eNAD+, zvichiita kuti ishande zvakapetwa kaviri pane glucose kana tichitarisa kugadzirwa kwemafree radicals.

Ongororo inoratidzawo kuti BHB haingogone kuchengetedza chiyero cheNAD+/NADH chete, asiwo kuchiwedzera. Izvi zvinoreva kuti BHB inogona:

●Dzivirira kushushikana kwe oxidative uye ma oxidants anokonzerwa nekuora kwe ketone

● Inotsigira mashandiro emitochondrial uye kubereka

●Inopa simba rekudzivirira kukwegura uye kurarama kwenguva refu

BHB inoshandawo se antioxidant nekushandisa mapuroteni anodzivirira:

●UCP: Puroteni iyi inogona kudzima ma free radicals anobuda panguva yekushandiswa kwesimba uye kudzivirira kukuvara kwe oxidative kumasero.

●SIRT3: Kana muviri wako ukachinja kubva paglucose kuenda kumafuta, puroteni inonzi Sirtuin 3 (SIRT3) inowedzera. Inoita kuti ma antioxidants ane simba arambe akaderera panguva yekugadzira simba. Inoitawo kuti jini reFOXO rigadzikane uye inodzivirira oxidation.

●HCA2: BHB inogonawo kumutsa puroteni iyi yereceptor. Ongororo dzakawanda dzakaratidza kuti izvi zvinogona kutsanangura mhedzisiro yeBHB yekudzivirira tsinga.

Mabhenefiti gumi eBeta-Hydroxybutyric Acid (BHB) ekuvandudza hutano hwako

1. BHB inokurudzira kuratidzwa kwemajini akasiyana-siyana anokurudzira hutano.

BHB i "metabolite inoburitsa zviratidzo" inokurudzira shanduko dzakasiyana-siyana dze epigenetic mumuviri wese. Kutaura zvazviri, mabhenefiti mazhinji eBHB anobva mukukwanisa kwayo kugadzirisa magene. Semuenzaniso, BHB inodzivirira mamorekuru anonyaradza mapuroteni ane simba. Izvi zvinobvumira kuratidzwa kwemajini anobatsira akadai seFOXO neMTL1.

Kushanda kweFOXO kunotibvumira kudzora zvakanyanya kupesana nekushushikana kwe oxidative, metabolism, circuit yemasero uye apoptosis, izvo zvine simba rakanaka pahupenyu hwedu uye simba redu. Uyezve, MLT1 inobatsira kuderedza chepfu mushure mekukurudzirwa kwekushandiswa kwayo neBHB.

Iyi ingori mienzaniso miviri yemhedzisiro yemajini eBHB pamasero edu. Masayendisiti achiri kutsvaga mamwe mabasa emamorekuru aya anoshamisa.

2. BHB inoderedza kuzvimba.

BHB inovhara puroteni inorwisa muviri inonzi NLRP3 inflammasome. NLRP3 inoburitsa mamorekuru anorwisa muviri akagadzirirwa kubatsira muviri kupora, asi kana akatsamwa nguva dzose anogona kukonzera kenza, insulin resistance, bone disease, Alzheimer's disease, skin diseases, metabolic syndrome, type 2 diabetes uye gout.

Ongororo dzakawanda dzakawana kuti BHB inogona kubatsira kudzivirira zvirwere zvinokonzerwa kana kuti zvinowedzerwa nekuzvimba nekuderedza kuzvimba kunokonzerwa nemamiriro aya.

Semuenzaniso, BHB (uye ketogenic diet) zvinogona kubatsira kurapa gout nekudzivirira kurwiswa kwegout nekudzivirira NLRP3.

3. BHB inodzivirira kubva mukushushikana kwe oxidative.

Kushushikana kwe oxidative kunobatanidzwa nekukwegura nekukurumidza uye matambudziko akasiyana-siyana ehutano husingaperi. Imwe nzira yekuderedza matambudziko aya ndeyekushandisa mafuta anoshanda zvakanaka akadai seBHB.

BHB haisi kungoshanda zvakanyanya kupfuura shuga chete, zvidzidzo zvakawana kuti inogona kudzivirira uye kudzora kukuvara kwe oxidative muuropi nemuviri wese:

●BHB inodzivirira kubatana kwetsinga dzeuropi mu hippocampus, chikamu cheuropi chinodzora manzwiro, ndangariro yenguva refu, uye kufamba kwenzvimbo, kubva mukukuvadzwa kwe oxidative.

●Muuropi, nzvimbo yeuropi ine basa rekuita mabasa epamusoro akadai sekuziva, kufunga kwenzvimbo, mutauro, uye kunzwisisa kwemanzwiro, BHB inodzivirira masero etsinga kubva kuma free radicals uye oxidation.

●Mumasero endothelial (masero ari mutsinga dzeropa), maketone anomutsa masisitimu ekudzivirira ane antioxidant anodzivirira hurongwa hwemwoyo.

●Muvatambi, ma ketone bodies akawanikwa achideredza kushushikana kwe oxidative kunokonzerwa nekurovedza muviri.

4. BHB inogona kuwedzera hupenyu hwemuviri.

Nekuwana mabhenefiti maviri atakadzidza nezvawo kare (kudzikira kwekuzvimba uye kuratidzwa kwemajini), BHB inogona kuwedzera hupenyu hwako uye kuita kuti hupenyu hwako huve hwakasimba.

Aya ndiwo mashandisiro anoita BHB mumajini ako anodzivirira kukwegura:

●Bvisa gene remugamuchiri we insulin-like growth factor (IGF-1). Jini iri rinokurudzira kukura kwemasero uye kuwanda kwawo, asi kukura kwakawanda kwakabatana nezvirwere, kenza, uye kufa nekukurumidza. Kuderera kwekushanda kweIGF-1 kunononotsa kukwegura uye kunoita kuti hupenyu huve hurefu.

●Shandisa jini reFOXO. Rimwe jini reFOXO, FOXO3a, rave richibatanidzwa nekuwedzera hupenyu hwevanhu nekuti rinokurudzira kugadzirwa kweantioxidants.

 

5. BHB inowedzera mashandiro epfungwa.

Takambokurukura kuti BHB inzvimbo inokosha yemafuta kuuropi kana shuga yakaderera. Izvi zvinodaro nekuti inogona kuyambuka zviri nyore chipingamupinyi cheropa neuropi uye inopa simba rinodarika 70% yezvinodiwa neuropi.

Zvisinei, mabhenefiti eBHB muuropi haagumiri ipapo. BHB inogonawo kuvandudza mashandiro epfungwa ne:

● Inoshanda semushonga unodzivirira tsinga.

●Kuvandudza kushanda zvakanaka kwemitochondrial uye kugona kubereka.

●Kuvandudza kuenzana pakati pezvinokonzeresa tsinga dzeuropi zvinodzivisa tsinga nezvinokonzeresa tsinga.

●Kurudzira kukura nekusiyana kwema neuron matsva nekubatana kwema neuron.

●Dzivirira brain atrophy uye plaque kuungana.

Kana uchida kudzidza zvakawanda nezvekuti BHB inobatsira sei uropi uye tsvakiridzo iri shure kwayo, tarisa chinyorwa chedu pamusoro pemaketone neuropi.

6. BHB inogona kubatsira kurwisa nekudzivirira kenza.

BHB inononotsa kukura kwemabundu akasiyana-siyana nekuti masero mazhinji ekenza haakwanise kushandisa zvizere ma ketone bodies kuti akure nekupararira. Izvi zvinowanzokonzerwa nekushaikwa kwemetabolism yemasero ekenza, zvichiita kuti anyanye kuvimba neshuga.

Muzvidzidzo zvakawanda, masayendisiti akashandisa kusasimba uku nekubvisa shuga, zvichimanikidza masero ekenza kuvimba ne ketone bodies. Nenzira iyi, vakaderedza bundu munhengo dzakawanda dzemuviri, kusanganisira uropi, pancreas ne colon, nekuti masero acho akanga asingakwanisi kukura nekupararira.

Zvisinei, zvakakoshawo kuziva kuti haasi magomarara ese anoita zvinhu zvakafanana, uye BHB haibatsire kurwisa nekudzivirira magomarara ese. Kana uchida kudzidza zvakawanda nezvetsvagurudzo pamusoro peketo, kudya kweketogenic, uye gomarara, tarisa chinyorwa chedu pamusoro penyaya iyi.

7. BHB inowedzera insulini kunzwa.

Maketone anogona kubatsira kuderedza kusawirirana kweinsulin nekuti anogona kutevedzera zvimwe zvezvinokonzereswa neinsulin uye kudzora huwandu hweshuga muropa uye huwandu hweinsulin. Aya mashoko akanaka kune chero munhu ane prediabetes kana chirwere cheshuga cherudzi rwechipiri, kana chero ani zvake anoda kuvandudza hutano hwavo hwese hwemetabolism.

8. BHB ndiyo mafuta akanakisa emwoyo wako.

Simba rinodiwa nemoyo i long-chain fatty acids. Ndizvozvo, moyo unopisa mafuta, kwete ma ketone, senzvimbo huru yemafuta.

Zvisinei, kungofanana neuropi, moyo wako unogona kuchinjika zvakanaka ku keto kana zvichidikanwa.

Ongororo dzakawana kuti kana ukapisa BHB, hutano hwemwoyo wako hunovandudzika munzira dzakawanda 

●Kushanda zvakanaka kwemoyo kunogona kuwedzerwa kusvika pa30%

●Kuyerera kweropa kunogona kuwedzerwa kusvika pa75%.

●Kushushikana kwe oxidative mumasero emwoyo kunoderera.

Kana zvabatanidzwa, izvi zvinoreva kuti BHB inogona kunge iri mafuta akanakisa emwoyo wako.

9. BHB inokurumidza kurasikirwa nemafuta.

Kupisa ma ketones semafuta kunogona kukonzera kurasikirwa kwemafuta nenzira mbiri:

●Nekuwedzera kugona kwako kupisa mafuta ne ketone.

●Nekudzikisira chido chekudya.

Sezvaunoramba uine ketosis, kugona kwako kupisa maketone akawanda nemafuta kuchawedzera zvakanyanya, zvichikuita muchina unopisa mafuta. Pamusoro peizvi, uchasanganawo nemhedzisiro yekudzora chishuwo chekudya yeketones.

Kunyange hazvo tsvakurudzo isati yaratidza kuti sei kana kuti sei ma ketone anoderedza chishuwo chedu chekudya, tinoziva kuti kuwedzera kwekupisa ma ketone kunoita sekunoderedza huwandu hwe ghrelin, iyo hormone yenzara.

Kana tikabatanidza migumisiro miviri iyi yeBHB pakuderedza uremu, tinopedzisira tava nemafuta anokurudzira kupisa mafuta uye panguva imwe chete anokudzivirira kuti usawane mafuta (nekudzivirira kudya macalorie akawandisa).

10. BHB inowedzera kushanda kwekurovedza muviri kwako.

Kwave nekutsvagurudzwa kwakawanda pamusoro pekuti BHB inokanganisa sei mashandiro emitambo, asi zvinhu chaizvo zvichiri kuongororwa (zvichitaurwa nemutauro). Muchidimbu, zvidzidzo zvakawana kuti ma ketone anogona:

●Kuvandudza mashandiro emuviri panguva yekudzidzira kutsungirira zvine simba rakaderera kusvika pakati nepakati (semuenzaniso, kutasva bhasikoro, kufamba netsoka, kutamba, kushambira, yoga yesimba, kurovedza muviri, kufamba daro refu).

● Wedzera kupisa mafuta uye chengetedza glycogen muzvitoro zvekurovedza muviri kwakasimba.

●Inobatsira kuzadza glycogen yakachengetwa nenzira isina kunanga mushure mekurovedza muviri uye kukurumidzisa kupora.

●Inoderedza kuneta panguva yekushanda uye inovandudza mashandiro epfungwa.

Zvose, tsvakurudzo inoratidza kuti BHB inogona kubatsira kuderedza kuneta, kuwedzera kutsungirira, uye zvingangovandudza mashandiro ekurovedza muviri. Zvisinei, hazvizovandudze mashandiro ako mumabasa ekurovedza muviri ane simba rakanyanya sekumhanya nekusimudza zvinorema. (Kuti uwane chikonzero, inzwa wakasununguka kutarisa gwara redu rekurovedza muviri kwe ketogenic.)

Kune nzira mbiri dzekuwedzera mazinga ako eBHB: endogenously uye exogenously.

BHB yemukati inogadzirwa nemuviri wako wega.

Maketone ekunze ndiwo mamorekuru eBHB ekunze anogona kutorwa sekuwedzera kuwedzera mazinga eketone nekukurumidza. Aya anowanzo torwa muchimiro chemunyu weBHB kana maester.

Nzira chete yekugadzirisa uye kuchengetedza huwandu hweketone ndeyekugadzira maketones mumuviri. Kuwedzera ketone kubva kunze kunogona kubatsira, asi hakumbofi kwakatsiva mabhenefiti ekudya kunoenderera mberi.

Exogenous Ketosis: Zvese Zvaunoda Kuziva NezveBHB Ketone Supplement

Kune nzira mbiri dzakajairika dzekuwana ma ketone ekunze: BHB salts nema ketone esters.

Maketone esters ndiwo rudzi rwekutanga rweBHB pasina zvimwe zvinhu zvakawedzerwa. Anodhura, akaoma kuwana, anonaka zvakaipa, uye anogona kukanganisa dumbu.

Kune rumwe rutivi, munyu weBHB chinhu chinobatsira zvikuru uye chiri nyore kutenga, kudya, uye kugaya. Izvi zvinowedzera ketone zvinowanzogadzirwa nemusanganiswa weBHB nemunyu wemaminerari (semuenzaniso potassium, calcium, sodium, kana magnesium).

Munyu wemineral unowedzerwa kune exogenous BHB supplements kune:

●Simba remaketone akavharirwa

●Kuvandudza kuravira

●Deredzai kuwanda kwematambudziko emudumbu

●Gadzira kuti isanganiswe nechikafu nezvinwiwa

Kana ukatora munyu weBHB, unopwanyika wobva waburitswa muropa rako. BHB inobva yaenda kunhengo dzako dzemuviri uko ketosis inotanga, ichikupa simba.

Zvichienderana nekuti wadya zvakawanda sei, unogona kupinda muketosis nekukasika. Zvisinei, unogona kuramba uri muketosis chero bedzi ma ketone bodies aya achiripo (kunze kwekunge uri pakudya kweketogenic uye watove uchigadzira ma ketones ega ega).

Ketone Ester (R-BHB) uye Beta-Hydroxybutyrate (BHB)

Beta-hydroxybutyrate (BHB) ndeimwe yemiviri mikuru mitatu yeketone inogadzirwa nechiropa panguva yekudya makabhohaidhiretsi mashoma, kutsanya, kana kurovedza muviri kwenguva refu. Kana huwandu hweshuga huri pasi, BHB inoshanda seimwe nzira yekupa simba kuuropi, tsandanyama, nedzimwe nhengo dzemuviri. Imorekuru inongoitika yoga inoita basa rakakosha mukuchinja kwemetabolism yeketosis.

Ketone ester (R-BHB), kune rumwe rutivi, imhando yeBHB yakagadzirwa yakabatana nemorekuru yedoro. Iyi mhando yakaongororwa inowanikwa zviri nyore uye inoshanda pakuwedzera mazinga eketone muropa kupfuura munyu weBHB wekare. R-BHB inowanzoshandiswa mukuwedzera simba remitambo, kushanda kwepfungwa, uye mazinga esimba rose.

Kana muviri wapinda muchimiro cheketosis, unotanga kuputsa mafuta acid kuita ma ketone, kusanganisira BHB. Maitiro aya anongoitika kuti muviri ugare uine simba shoma, zvichiita kuti simba rirambe richigadzirwa. BHB inozotakurwa nemuropa kuenda kunhengo dzakasiyana-siyana, uko inoshandurwa kuita simba.

R-BHB imhando yeBHB yakasimba uye ine simba inogona kuwedzera huwandu hweketone muropa nekukurumidza. Izvi zvinoita kuti ive sarudzo inokwezva kune avo vanotsvaga mabhenefiti eketosis vasina mitemo yakasimba yekudya. Tsvagiridzo inoratidza kuti R-BHB inogona kusimudzira mashandiro emuviri, kuvandudza mashandiro epfungwa, uye kutsigira kuedza kudzikisa uremu.

Nzira yekusarudza munyu weBHB wakanakira iwe

Paunenge uchitsvaga munyu weBHB wakanakisisa, iva nechokwadi chekuti unoita zvinhu zvitatu izvi:

1. Tsvaga BHB yakawanda uye munyu mushoma

Mishonga yemhando yepamusoro inowedzera BHB yekunze uye inowedzera huwandu hunodiwa hwemunyu wemaminerari.

Munyu wezvicherwa unonyanya kushandiswa pamusika i sodium, potassium, magnesium, uye calcium, uye mishonga yakawanda inoshandisa mitatu yacho, kunyange zvazvo mimwe inoshandisa imwe chete kana mbiri dzacho.

Tarisa pane label kuti uve nechokwadi chekuti pane iri pasi pegiramu imwe neimwe yemunyu wemineral. Musanganiswa wemunyu weBHB hauwanzodi anopfuura gramu imwe chete yemineral kuti ushande zvakanaka.

2. Iva nechokwadi chekuti uri kuwana zvicherwa zvaunoda.

Hauna potassium yakakwana, sodium, calcium kana magnesium here? Sarudza zvigadzirwa zveBHB kuti zvikupe zvicherwa zvaunoda.

3. Rega kushandisa zvinhu zvinozadza muviri uye zvinowedzerwa makabhohaidhiretsi.

Zvinhu zvinosimbisa magadzirirwo emuviri zvakaita seguar gum, xanthan gum, uye silica zvinowanikwa mu exogenous ketone salts uye hazvidiwi zvachose. Kazhinji hazvikuvadzi hutano, asi zvinogona kukutorera munyu weBHB unokosha.

Kuti uwane munyu weketo wakachena, ingotsvaga chikamu chiri pachinyorwa chezvekudya chakanzi "Zvimwe Zvimisikidzo" wobva watenga chigadzirwa chine runyorwa rupfupi rwezvinhu chaizvo.

Kana ukatenga BHB keto salts ine flavour, iva nechokwadi chekuti ine zvinhu chaizvo uye zvinotapira zvine carbohydrate shoma chete. Dzivisa chero zvinowedzerwa zvine carbohydrate zvakaita semaltodextrin nedextrose.

Suzhou Myland Pharm & Nutrition Inc. ikambani yakanyoreswa neFDA inopa Ketone Ester (R-BHB) yemhando yepamusoro uye yakachena.

KuSuzhou Myland Pharm takazvipira kupa zvigadzirwa zvemhando yepamusoro nemitengo yepamusoro. Upfu hwedu hweKetone Ester (R-BHB) hunoongororwa zvakasimba kuti hune kuchena uye simba, zvichiita kuti uwane chinowedzera chemhando yepamusoro chaunogona kuvimba nacho. Kunyangwe uchida kutsigira hutano hwemasero, kusimbisa masoja emuviri wako kana kusimudzira hutano hwese, Ketone Ester yedu (R-BHB) ndiyo sarudzo yakakwana.

Nemakore makumi matatu eruzivo uye zvichitungamirirwa netekinoroji yepamusoro uye nzira dzeR&D dzakanyatsogadzirwa, Suzhou Myland Pharm yakagadzira zvigadzirwa zvakasiyana-siyana zvinokwikwidzana uye yakava kambani itsva yekuwedzera sainzi yehupenyu, kugadzira zvinhu zvakagadzirwa uye kugadzira zvinhu.

Pamusoro pezvo, Suzhou Myland Pharm ikambani yakanyoreswa neFDA. Zvishandiso zveR&D zvekambani, nzvimbo dzekugadzira, uye zvishandiso zvekuongorora ndezvemazuva ano uye zvinoshanda zvakawanda, uye zvinogona kugadzira makemikari kubva pamamirigiramu kusvika kumatani muhukuru, uye zvinoenderana neISO 9001 standards uye specifications dzekugadzira GMP.