Chii chinonzi Beta-Hydroxybutyrate (BHB) & Hezvino Ndizvo Zvaunofanira Kuziva

Beta-hydroxybutyrate (BHB) imwe yematatu makuru ketone miviri inogadzirwa nechiropa panguva dzekudya kwekabhohydrate, kutsanya, kana kurovedza muviri kwenguva refu. Mimwe miviri yeketone ndeye acetoacetate uye acetone. BHB ndiyo yakawanda uye inobudirira yeketone muviri, ichibvumira kuti iite basa rinokosha mumuviri wesimba metabolism, kunyanya kana glucose iri shoma. Beta-hydroxybutyrate (BHB) ine simba ketone muviri unoita basa rinokosha musimba metabolism, kunyanya panguva ye ketosis. Mabhenefiti ayo anodarika kugadzirwa kwesimba kupa kuziva, huremu manejimendi, uye anti-kuzvimba mabhenefiti. Kunyangwe iwe uri kutevera ketogenic kudya kana kutarisa kuti uwedzere hutano hwako hwemagetsi, zvakakosha kuti unzwisise BHB nemabasa ayo.

Chii chinonzi beta-hydroxybutyrate (BHB)?

Beta-hydroxybutyrate (BHB) imwe yezvikamu zvitatu zveketone zvinogadzirwa nechiropa kana pane kushayikwa kwemakhahydrates. (Iyo inozivikanwawo se3-hydroxybutyrate kana 3-hydroxybutyric acid kana 3HB.)

Heino mhedziso pfupi yemitumbi yeketone chiropa chinokwanisa kugadzira:

Beta-Hydroxybutyrate (BHB). Iyi ndiyo ketone yakawanda kwazvo mumuviri, kazhinji inoverengera 78% yemaketone muropa. BHB ndiyo yekupedzisira chigadzirwa che ketosis.

Acetoacetate. Rudzi urwu rwemuviri weketone runoita nezve 20% yemitumbi yeketone muropa. BHB inogadzirwa kubva kuacetoacetate uye haigone kugadzirwa nemuviri chero imwe nzira. Zvakakosha kuziva kuti acetoacetate haina kugadzikana kudarika BHB, saka acetoacetate inogona kungoerekana yashandura kuacetone isati yaitika inoshandura acetoacetate kuBHB inoitika.

acetone. Zvishoma zvakazara ketoni; inotora inenge 2% yeketoni muropa. Haisi kushandiswa kwesimba uye inobudiswa kubva mumuviri pakarepo.

Zvose BHB uye acetone zvakatorwa kubva kuacetoacetate, zvisinei, BHB ndiyo yekutanga ketone inoshandiswa kune simba nokuti yakanyatsogadzikana uye yakawanda, asi acetone inorasika kuburikidza nekufema uye ziya.

Zvese zvaunoda kuti uzive nezveBHB

Munguva ye ketosis, matatu makuru marudzi emitumbi yeketone anogona kuonekwa muropa:

●acetoacetate

●β-Hydroxybutyrate (BHB)

●Acetone

BHB ndiyo ketone inoshanda zvakanyanya, inoshanda zvakanyanya kupfuura glucose. Haisi chete inopa simba rakawanda kupfuura shuga, inorwisawo kukuvara kweoxidative, inoderedza kuzvimba, uye inovandudza kushanda kwenhengo, kunyanya uropi.

Kana iwe uchida kuderedza uremu, kuwedzera kugona kwekuziva, uye kuwedzera hupenyu hwako, BHB ndiyo yako yakanakisa sarudzo.

Nzira iri nyore yekuwedzera BHB mazinga ndeyekutora exogenous ketoni uye MCT mafuta. Nekudaro, izvi zvinowedzera zvinogona chete kuwedzera ketone mazinga ako kusvika muviri wako wavashandisa.

Kuti usimudzire kugadzirwa kweBHB kwenguva refu nenzira ine utano, unofanira kutevera ketogenic diet.

Sezvo iwe uchigadzira chikafu, unogona kushandisa nzira dzakasiyana-siyana kuti uwedzere kuwedzera ketone kugadzirwa, kusanganisira:

● Deredza kudyiwa kwekabhohaidhireti isingasviki 15 gramu pazuva pavhiki yekutanga.

● Deplete glycogen store kuburikidza nepamusoro-soro kurovedza muviri.

● Shandisa yakaderera-kudzika-yepakati-yakasimba maitiro kuti uwedzere kupisa mafuta uye ketone kugadzirwa.

● Tevedzera hurongwa hwekutsanya.

Paunenge uchida kuwedzera simba, tora MCT Oiri yekuwedzera uye / kana BHB Keto Salts

Sei muviri wako uchida BHB? kubva pakuona kwekushanduka-shanduka

Muviri wako haunzwi here sekunge uri kuenda nekuedza kwakawanda kugadzira nekushandisa kunyange huwandu hushoma hwemaketoni? Haisi kupisa mafuta here? Zvakanaka, hongu uye kwete.

Fatty acids inogona kushandiswa sehuni yemasero mazhinji, asi kuhuropi, iwo anononoka. Uropi hunoda kukurumidza-kuita masimba masimba, kwete kunonoka-metabolizing mafuta semafuta.

Somugumisiro, chiropa chakagadzira kukwanisa kushandura mafuta asidhi kuva miviri yeketone—rimwe simba reuropi kana shuga isingakwani. Imi nenyanzvi dzesainzi kunze uko munogona kunge muchifunga: "Hatigone here kushandisa gluconeogenesis kupa shuga kuuropi?"

Hungu, tinogona-asi kana carbs yakaderera, tinofanira kuputsa anenge 200 gramu (inenge 0.5 pounds) yemhasuru pazuva uye kuishandura kuva shuga kuti tipise huropi hwedu.

Nekupisa ketoni dzehuni, tinochengetedza tsandanyama, tinopa chikafu kuuropi, uye kuwedzera hupenyu kana chikafu chishoma. Muchokwadi, ketosis inogona kubatsira kuderedza kuonda kwemuviri kurasikirwa panguva yekutsanya ne5-kupeta.

Mune mamwe mazwi, kushandisa ketoni kwehuni kunoderedza kudiwa kwedu kupisa tsandanyama kubva pa200 gramu kusvika ku40 magiramu pazuva kana chikafu chiri chishoma. Zvisinei, kana iwe uchitevera kudya kwe ketogenic kuti uremerwe uremu, iwe ucharasikirwa kunyange pasi pe40 magiramu emhasuru pazuva nokuti unenge uchipa muviri wako nemhasuru-inochengetedza mishonga yakadai seprotein.

Kwemavhiki kusvika kumwedzi yekudya ketosis (apo mazinga ako eketone ari pakati pe 0.5 ne 3 mmol / L), ketoni inosangana kusvika ku50% yebasal simba rako rinoda uye 70% yehuropi hwako hunoda simba. Izvi zvinoreva kuti iwe uchachengeta mhasuru yakawanda uchiwana zvese zvakanaka zvekupisa ketone:

Kuvandudza basa rekuziva uye kujeka kwepfungwa

●Shuga yemuropa yakatsiga

●Kuwedzera simba

●Kurasa mafuta

●Kutamba mitambo kuri nani

Sei muviri wako uchida BHB? kubva pa mechanical point of view

BHB haisi kutibatsira chete kudzivirira muscle atrophy, asi inopawo mafuta zvakanyanya kupfuura shuga nenzira mbiri:

●Inoburitsa mashoma emahara radicals.

● Inotipa simba rakawanda pamorekuru.

Kugadzirwa Kwemagetsi uye Mahara Radicals: Glucose (Shuga) vs. BHB

Patinogadzira simba, tinogadzira zvinhu zvinokuvadza zvinonzi ma free radicals (kana oxidants). Kana izvi byproducts zvikaungana nekufamba kwenguva, zvinogona kukanganisa maseru neDNA.

Munguva yekugadzirwa kweATP, okisijeni nehydrogen peroxide zvinobuda. Aya ndiwo mahara radicals, ayo anogona kurwisa zviri nyore ne antioxidants.

Nekudaro, ivo zvakare vane mukana wekubuda mukutonga uye kushanduka kuita zvakanyanya kukuvadza emahara radicals (kureva, reactive nitrogen marudzi uye hydroxyl radicals), ayo anokonzera kuwanda kwekukuvara kweoxidative mumuviri.

Naizvozvo, kuitira hutano hwakakwana, kuunganidza kusingagumi kwemahara radicals kunofanirwa kuderedzwa. Kuti tiite izvi, tinofanira kushandisa simba rakachena pose pazvinobvira.

Glucose uye yemahara radical kugadzirwa

Glucose inofanirwa kupfuura nepakati penguva yakati rebei kupfuura BHB isati yapinda muKrebs cycle kugadzira ATP. Kana maitirwo apera, mamorekuru mana eNADH achagadzirwa uye chiyero cheNAD +/NADH chinodzikira.

NAD+ neNADH zvakakosha nekuti zvinodzora oxidant uye antioxidant chiitiko:

●NAD+ inodzivirira kushushikana kweoxidative, kunyanya chero matambudziko anokonzerwa nechimwe chezvakambotaurwa: hydrogen peroxide. Iyo zvakare inosimudzira autophagy (maitiro ekuchenesa nekuvandudza akakuvadzwa maseru zvikamu). Pasi pechiito cheakasiyana metabolic maitiro, NAD + inova NADH, inoshanda seye electron shuttle yekugadzira simba.

●NADH inofanirwawo nekuti inopa maerekitironi ekugadzira ATP. Nekudaro, haidziviriri kubva kune mahara radical kukuvara. Kana paine NADH yakawanda kupfuura NAD +, mamwe ma radicals emahara anogadzirwa uye ma enzymes ekudzivirira anovharirwa.

Mune mamwe mazwi, kazhinji, iyo NAD +/NADH chiyero inochengetedzwa zvakanyanya. Yakaderera NAD + mazinga anogona kukonzera yakanyanya oxidative kukuvara kumasero.

Sezvo glucose metabolism ichidya 4 NAD + mamorekuru, iyo NADH yemukati ichave yakakwirira, uye NADH inokonzeresa kukuvara kweoxidative. Muchidimbu: Glucose haina kupiswa zvachose-kunyanya ichienzaniswa neBHB.

BHB uye yemahara radical kugadzirwa

BHB haina kuita glycolysis. Inongochinja ichidzokera kuita acetyl-CoA isati yapinda muKrebs cycle. Pakazere, maitiro aya anongopedza 2 NAD + mamorekuru, zvichiita kuti ishande zvakapetwa kaviri seglucose kubva pamaonero emahara radical kugadzirwa.

Tsvagiridzo inoratidzawo kuti BHB haingogone kuchengetedza iyo NAD +/NADH ratio, asi zvakare kuivandudza. Izvi zvinoreva kuti BHB inogona:

● Kudzivirira oxidative kusagadzikana uye oxidants inogadzirwa panguva yekuparara kweketone

● Inotsigira mitochondrial basa uye kubereka

● Inopa anti-kuchembera uye hupenyu hurefu mhedzisiro

BHB inoshandawo se antioxidant nekuita mapuroteni anodzivirira:

● UCP: Iri puroteni rinogona kuderedza mahara radicals inodonha panguva yesimba metabolism uye kudzivirira kukuvadzwa kweoxidative kumaseru.

●SIRT3: Kana muviri wako uchichinja kubva kuglucose kuenda kumafuta, puroteni inonzi Sirtuin 3 (SIRT3) inowedzera. Inomisikidza ane simba antioxidants ayo anochengeta mahara radical mazinga akaderera panguva yekugadzira simba. Iyo zvakare inodzikamisa iyo FOXO gene uye inodzivirira oxidation.

●HCA2: BHB inogonawo kushandisa iyi receptor protein. Zvidzidzo zvakawanda zvakaratidza kuti izvi zvinogona kutsanangura neuroprotective mhedzisiro yeBHB.

10 Zvakanakira Beta-Hydroxybutyric Acid (BHB) Kusimudzira Hutano Hwako

1. BHB inokurudzira kutaura kwemajini akasiyana-siyana anosimudzira hutano.

BHB i "signaling metabolite" inokurudzira kuchinja kwakasiyana-siyana epigenetic mumuviri wose. Muchokwadi, mazhinji emabhenefiti eBHB anouya kubva mukugona kwayo kukwidziridza gene kutaura. Semuenzaniso, BHB inhibits mamorekuru anonyaradza mapuroteni ane simba. Izvi zvinobvumira kutaura kwemajini anobatsira akadai seFOXO neMTL1.

Activation yeFOXO inotibvumira kunyatso gadzirisa kuramba kune oxidative kusagadzikana, metabolism, sero kutenderera uye apoptosis, iyo ine maitiro akanaka pahupenyu hwedu uye simba. Uyezve, MLT1 inobatsira kuderedza huturu mushure mekusimudzira kwekutaura kwayo neBHB.

Iyi ingori mienzaniso miviri yemageneti eBHB pamasero edu. Masayendisiti achiri kuongorora mamwe mabasa eaya mamorekuru anoshamisa.

2. BHB inoderedza kuzvimba.

BHB inovhara puroteni inoputika inonzi NLRP3 inflammasome. NLRP3 inoburitsa mamorekuru anokonzeresa akagadzirirwa kubatsira muviri kupora, asi kana vachinge vatsamwa vanokwanisa kuita kenza, insulin kuramba, chirwere chemapfupa, chirwere cheAlzheimer, chirwere cheganda, metabolic syndrome, rudzi rwechipiri chirwere cheshuga uye gout.

Zvidzidzo zvakawanda zvakaona kuti BHB inogona kubatsira kudzivirira zvirwere zvinokonzerwa kana kuipa nekuputika nekuderedza kupisa kunobatanidza nemamiriro aya.

Semuenzaniso, BHB (uye ketogenic diet) inogona kubatsira kubata gout uye kudzivirira gout kurwiswa nekudzivisa NLRP3.

3. BHB inodzivirira kubva kune oxidative stress.

Oxidative stress inosanganiswa nekukurumidzira kuchembera uye akasiyana ehutano asingaperi matambudziko. Imwe nzira yekudzikisa matambudziko aya ndeyekushandisa yakanyatsoshanda mafuta sosi seBHB.

Haisi chete BHB inoshanda kupfuura shuga, zvidzidzo zvakawana kuti inogona kudzivirira uye kudzosera kukuvadzwa kweiyo oxidative muuropi nemuviri wese:

● BHB inodzivirira kutendeseka kwekubatana neuronal mu hippocampus, chikamu cheuropi chinogadzirisa mafungiro, nguva refu yekuyeuka, uye nzvimbo yekufamba, kubva pakukanganiswa kweoxidative.

● Mu cerebral cortex, nzvimbo yeuropi inotarisira mabasa epamusoro-soro akadai sekuziva, kufunga kwepakati, mutauro, uye maonero ekunzwa, BHB inodzivirira masero etsinga kubva kune mahara radicals uye oxidation.

● Mune endothelial masero (masero anoisa tsinga dzeropa), ketones activate antioxidant defense systems inodzivirira yemwoyo.

● Muvatambi, miviri yeketone yakawanikwa kuderedza kurovedza-induced oxidative stress.

4. BHB inogona kuwedzera hupenyu.

Nekutsvaga zviviri zvezvikomborero zvatakadzidza pamusoro pekare (kuderedza kuzvimba uye gene expression), BHB inogona kuwedzera hupenyu hwako uye kuita kuti hupenyu hwako hupfume.

Iyi ndiyo nzira iyo BHB inopinda nayo mumajeni ako ekurwisa kuchembera:

● Vharai insulini-yakafanana nekukura chinhu (IGF-1) gene receptor. Jeni iri rinokurudzira kukura kwesero uye kuwanda, asi kukura kwakabatana nehosha, kenza, uye kufa kwekutanga. Yakaderera IGF-1 basa rinononoka kuchembera uye rinowedzera hupenyu.

● Shandisa FOXO gene. Imwe chaiyo FOXO gene, FOXO3a, yakabatanidzwa nekuwedzera hupenyu muvanhu nekuti inosimudzira kugadzirwa kwema antioxidants.

 

5. BHB inosimudzira basa rekuziva.

Takakurukura zvisati zvaitika kuti BHB inzvimbo yakakosha yehuni yehuropi kana shuga yakaderera. Izvi zvinodaro nekuti inogona kuyambuka zviri nyore chipingamupinyi cheropa-uropi uye kupa zvinopfuura 70% yesimba rehuropi.

Nekudaro, mabhenefiti ehuropi eBHB haagumire ipapo. BHB inogonawo kuvandudza basa rekuziva ne:

● Inoshanda se neuroprotective antioxidant.

● Kuvandudza mitochondrial kunyatsoshanda uye kukwanisa kubereka.

● Kuvandudza chiyero pakati pe inhibitory uye excitatory neurotransmitters.

●Kurudzira kukura nekusiyaniswa kwemaneuron matsva uye neuronal connections.

● Kudzivirira kuora kweuropi uye kuungana kweplaque.

Kana iwe uchida kudzidza zvakawanda pamusoro pekuti BHB inobatsira sei uropi uye tsvakurudzo shure kwayo, tarisa chinyorwa chedu pamusoro peketoni uye uropi.

6. BHB inogona kubatsira kurwisa nekudzivirira kenza.

BHB inononoka kukura kwezvipembenene zvakasiyana-siyana nokuti masero emukenza akawanda haakwanisi kushandisa zvizere miviri yeketone kukura nekupararira. Izvi zvinowanzoitika nekuda kwekukanganiswa kwemasabolism emasero egomarara, zvichiita kuti vavimbe zvakanyanya neshuga.

Muzvidzidzo zvakawanda, masayendisiti akashandisa kushaya simba uku nekubvisa glucose, kumanikidza masero ekenza kuvimba nemitumbi yeketone. Nenzira iyi, ivo vakatodzikisa mapundu munhengo dzakawanda, kusanganisira uropi, pancreas uye colon, nekuti masero akange asingakwanisi kukura nekupararira.

Zvisinei, zvakakoshawo kuziva kuti havasi vese vane gomarara vanoita nenzira imwe chete, uye BHB haibatsiri kurwisa nekudzivirira magomarara ese. Kana iwe uchida kudzidza zvakawanda nezve tsvagiridzo ye keto, iyo ketogenic chikafu, uye kenza, tarisa chinyorwa chedu pamusoro penyaya.

7. BHB inowedzera insulini kunzwa.

Ketoni inogona kubatsira kudzoreredza insulin kuramba nekuti vanogona kutevedzera mamwe emhedzisiro ye insulin uye kutonga shuga yeropa uye insulin mazinga. Idzi inhau dzakanaka kune chero munhu ane prediabetes kana Type 2 chirwere cheshuga, kana chero munhu anoda kuvandudza hutano hwavo hwese metabolic.

8. BHB ndiyo mafuta akanakisa emwoyo wako.

Simba rinofarirwa nemoyo ndiwo marefu-chain ane fatty acids. Ndizvozvo, mwoyo unopisa mafuta, kwete ketoni, semafuta ayo ekutanga.

Nekudaro, kungofanana nehuropi, moyo wako unogona kuenderana neketo kana zvichidikanwa.

Zvidzidzo zvakawana kuti paunopisa BHB, hutano hwemwoyo wako hunovandudza nenzira dzakawanda 

●Kushanda kwemagetsi kwemoyo kunogona kuwedzerwa kusvika ku30%

● Kuyerera kweropa kunogona kuwedzerwa kusvika pa75%.

● Oxidative stress mumasero emwoyo inoderedzwa.

Kutorwa pamwechete, izvi zvinoreva kuti BHB inogona kunge iri mafuta akanakisa emoyo wako.

9. BHB inokurumidza kurasikirwa nemafuta.

Kupisa ketoni dzehuni kunogona kukurudzira kurasikirwa kwemafuta nenzira mbiri:

● Nekuwedzera mafuta ako uye ketone kupisa masimba.

●Nekubvisa havi yekudya.

Sezvo iwe uchichengetedza mamiriro e ketosis, kugona kwako kupisa ketoni uye mafuta akawanda kuchawedzera zvakanyanya, kukuita iwe muchina unopisa mafuta. Pamusoro peizvi, iwe uchaonawo kudya-kudzvinyirira mhedzisiro yemaketone.

Nepo tsvakiridzo isati yaratidza kuti sei kana kuti matuturu anoderedza sei kudya kwedu, tinoziva kuti kuwedzera kutsva kweketone kunoratidzika kuderera mazinga eghrelin, iyo nzara hormone.

Apo patinobatanidza izvi zviviri zvinokonzerwa neBHB pakuderedza uremu, tinoguma nemafuta izvo zvose zvinokurudzira kupisa mafuta uye panguva imwechete zvinokudzivirira kuti urege kuwana mafuta (nekudzivirira kuwandisa koriori kushandiswa).

10. BHB inosimudzira kushanda kwemabasa ako.

Pakave nekutsvagisa kwakawanda pamusoro pekuti BHB inobata sei kuita kwemitambo, asi izvo chaizvo zvichiri kuitwa kunze (pun yaida). Muchidimbu, zvidzidzo zvakawana kuti ketoni inogona:

●Kunatsiridza mashandiro panguva yekudzidzira kushingirira kwakaderera kusvika pakati nepakati (semuenzaniso, kuchovha bhasikoro, kukwira makomo, kutamba, kushambira, yoga yesimba, maekisesaizi, kufamba daro refu).

● Wedzera kutsva kwemafuta uye chengetedza zvitoro zveglycogen zvekushanda zvakanyanya.

● Inobatsira kuzadza glycogen zvisina kunanga mushure mekuita maekisesaizi uye kukurumidza kupora.

● Inoderedza kuneta panguva yebasa uye inovandudza cognitive basa.

Pakazara, tsvagiridzo inoratidza kuti BHB inogona kubatsira kuderedza kuneta, kuwedzera kutsungirira, uye zvinogona kuvandudza kuita kwese kwekuita maekisesaizi. Nekudaro, hazvizonatsiridza mashandiro ako mumabasa akanyanya-kusimba senge sprinting uye weightlifting. (Kuti uzive chikonzero, inzwa wakasununguka kutarisa gwara redu rekuita ketogenic.)

Pane nzira mbiri dzekuwedzera yako BHB mazinga: endogenously uye exogenously.

Endogenous BHB inogadzirwa nemuviri wako wega.

Exogenous ketoni ndeyekunze BHB mamorekuru anogona kutorwa sekuwedzera kuti nekukurumidza awedzere ketone mazinga. Izvi zvinowanzotorwa nenzira yeBHB salts kana esters.

Iyo chete nzira yekunyatso optimize uye kuchengetedza ketone mazinga ndeye endogenous kugadzirwa kwemaketone. Exogenous ketone supplementation inogona kubatsira, asi haigone kutsiva mabhenefiti ekuenderera mberi kwehutano ketosis.

Exogenous Ketosis: Zvese Zvaunoda Kuziva NezveBHB Ketone Supplement

Pane nzira mbiri dzakajairika dzekuwana exogenous ketoni: BHB munyu uye ketone esters.

Ketone esters ndiyo yepakutanga fomu yeBHB isina zvimwe zvinongedzo zvakawedzerwa. Iwo anodhura, akaoma kuwana, anoravira zvinotyisa, uye anogona kuve nemhedzisiro yakaipa pagastrointestinal system.

BHB munyu, kune rumwe rutivi, isimba rinowedzera iro riri nyore kutenga, kushandisa, uye kugaya. Izvi ketone zvinowedzera zvinowanzoitwa kubva mukusanganiswa kweBHB uye mineral salts (kureva potassium, calcium, sodium, kana magnesium).

Mineral munyu inowedzerwa kune exogenous BHB yekuwedzera kune:

●Kusimba kwemaketone akavharwa

●Kunatsiridza kuravira

●Kuderedza kuwanda kwedambudziko remudumbu

●Ita kuti zvisanganiswe nechikafu nezvinwiwa

Paunotora BHB salts, inoputsika uye inosunungurwa muropa rako. BHB inobva yaenda kunhengo dzako uko ketosis inotanga, ichikupa simba.

Zvichienderana nekuti ingani yaunotora, iwe unogona kupinda mamiriro e ketosis nekukurumidza. Zvisinei, iwe unogona kungoramba uri mu ketosis chero bedzi miviri iyi yeketone ichiramba (kunze kwekuti iwe uri pane ketogenic kudya uye uri kutogadzira ketoni endogenous).

Ketone Ester (R-BHB) uye Beta-Hydroxybutyrate (BHB)

Beta-hydroxybutyrate (BHB) ndeimwe yematatu matatu makuru eketone anogadzirwa nechiropa panguva dzekudya kwekabhohydrate, kutsanya, kana kurovedza muviri kwenguva refu. Kana mazinga eglucose akadzikira, BHB inoshanda seimwe simba sosi yekupisa huropi, tsandanyama, uye mamwe matishu. Iyo molecule inowanzoitika inoita basa rakakosha mu metabolic mamiriro e ketosis.

Ketone ester (R-BHB), kune rumwe rutivi, imhando yekugadzira yeBHB yakasungirirwa kune molecule yedoro. Iyi esterified fomu inowedzera bioavailable uye inoshanda pakuwedzera mazinga eropa ketone kupfuura echinyakare BHB munyu. R-BHB inowanzoshandiswa mukuwedzera kuwedzera kwemitambo, basa rekuziva, uye simba rose remasimba.

Apo muviri unopinda mumamiriro e ketosis, unotanga kuputsa mafuta acids mumaketone, kusanganisira BHB. Iyi nzira ndeyekugadziriswa kwechisikigo kune nguva dzekuwanikwa kwakaderera kwecarbohydrate, zvichibvumira muviri kuchengetedza kugadzirwa kwesimba. BHB inobva yatakurwa kuburikidza neropa kusvika kune zvakasiyana-siyana, iyo inoshandurwa kuva simba.

R-BHB inonyanya kukoshesa, fomu yakasimba yeBHB inogona kukurumidza kuwedzera mazinga eropa ketone. Izvi zvinoita kuti ive sarudzo inokwezva kune avo vari kutsvaga mabhenefiti eketosis pasina kuomesesa kwekudya kurambidzwa. Tsvagiridzo inoratidza kuti R-BHB inogona kukwidziridza kuita kwemuviri, kuvandudza kugona kwekuziva, uye kutsigira uremu kuedza.

Nzira yekusarudza yakanakisa BHB munyu kwauri

Paunenge uchitsvaga yakanakisa BHB munyu, ita shuwa kuti unoita zvinhu zvitatu izvi:

1. Tsvaga BHB yakawanda uye munyu mushoma

Yepamusoro-mhando yekuwedzera inowedzera exogenous BHB uye inowedzera chete huwandu hunodiwa hwemamineral salt.

Mamineral salt anonyanya kushandiswa pamusika ndeye sodium, potassium, magnesium, uye calcium, ane akawanda ekuwedzera achishandisa matatu acho, kunyangwe vamwe vachingoshandisa imwe chete kana maviri acho.

Tarisa chinyorwa kuti uone kuti pane isingasviki 1 giramu yega yega mineral salt. BHB munyu inosanganiswa haiwanzoda zvinopfuura 1 gramu yemaminerari ega ega kuti ishande

2. Iva nechokwadi chokuti uri kuwana zvicherwa zvaunoda.

Kwete kuwana potassium yakakwana, sodium, calcium kana magnesium? Sarudza zvigadzirwa zveBHB kukupa zvicherwa zvaunoda.

3. Gara kure nemafillers uye akawedzera carbs.

Mafirita uye manyoro ekuwedzera senge guar gum, xanthan chingamu, uye silica zvakajairika mune exogenous ketone munyu uye hazvina basa zvachose. Kazhinji havana mhedzisiro yehutano hwakashata, asi vanogona kukubira yakakosha BHB munyu.

Kuti uwane iyo yakachena keto munyu, ingotarisa chikamu pane chikafu chekudya chinoti "Zvimwe Ingredients" uye tenga chigadzirwa nerunyoro rupfupi rwezvigadzirwa chaizvo.

Kana iwe ukatenga flavoured BHB keto munyu, ita shuwa kuti inongori nechaiyo zvinhu uye yakaderera-carb zvinotapira. Dzivisa chero carbohydrate-ine additives akadai maltodextrin uye dextrose.

Suzhou Myland Pharm & Nutrition Inc. ndeye FDA-yakanyoreswa mugadziri inopa yepamusoro-mhando uye yakakwirira-kuchena Ketone Ester (R-BHB).

PaSuzhou Myland Pharm takazvipira kupa zvigadzirwa zvemhando yepamusoro nemitengo yakanakisa. Yedu Ketone Ester (R-BHB) powder inoedzwa zvakasimba kuchena uye potency, kuve nechokwadi kuti iwe unowana chepamusoro chekuwedzera chaunogona kuvimba nacho. Kunyangwe iwe uchida kutsigira hutano hweserura, kuwedzera immune system yako kana kuwedzera hutano hwese, yedu Ketone Ester (R-BHB) ndiyo sarudzo yakakwana.

Iine makore makumi matatu echiitiko uye ichisundwa nehunyanzvi hwepamusoro uye akakwenenzverwa zvakanyanya R&D mazano, Suzhou Myland Pharm yakagadzira mhando yezvigadzirwa zvemakwikwi uye ive yekuvandudza hupenyu hwesainzi yekuwedzera, tsika synthesis uye kugadzira masevhisi kambani.

Uye zvakare, Suzhou Myland Pharm zvakare iri FDA-yakanyoreswa mugadziri. Zviwanikwa zvekambani zveR&D, zvivakwa zvekugadzira, uye zviridzwa zvekuongorora ndezvazvino uye zvinoshanda-akawanda, uye zvinogona kugadzira makemikari kubva kumamirigiramu kusvika kumatani muchiyero, uye zvinoenderana neISO 9001 zviyero uye magadzirirwo ekugadzira GMP.