Kuburitsa Mafambiro Azvino muAlpha GPC Supplements ye2024

Choline Alfoscerate,inozivikanwawo seAlpha-GPC, chinhu chinotorwa kubva mu lecithin yemiti, asi haisi phospholipid, asi phospholipid inobva muzvinhu zvine mafuta akawanda eLipophilic. Alpha-GPC chikafu chinoshanda zvakawanda chinowanikwa mumasero ese emhuka dzinoyamwisa. Nekuti inonyungudika zvakanyanya, inonyungudika nekukurumidza mushure mekunwa. GPC inotungamira kune acetylcholine (ACh) uye ine vimbiso huru mukusashanda zvakanaka kwecholine.

GPC inoyambuka zviri nyore chipingamupinyi cheropa-uropi uye inopa sosi yecholine yekugadzira ACh nephosphatidylcholine. Maphospholipid neacetylcholine, kana zvikawanikwa padanho rakanaka, zvinosimudzira hutano hwepfungwa, hwepfungwa uye hwetsinga dzeropa. Pamusoro pezvo, kuwanda kwakaringana kweAlpha-GPC neAch kunogona kukurudzira maitiro emuviri uye kuvandudza mashandiro emuviri. ACh inobata basa mukudzikira kwetsandanyama uye ndiyo neurotransmitter huru inodzora mhinduro dzemuviri pakurovedza muviri.

Sezvo mafambiro ese emhasuru ane chekuita nekudzika kwetsinga, uye kudzikira kwetsinga kwakabatana nehuwandu hweACh mumasero huripo, kuwedzera huwandu hweACh kunovandudza mashandiro etsinga. Zvichienzaniswa nezvimwe zvinozivikanwa zve choline precursors, Alpha-GPC inowedzera zvakachengeteka uye zvinobudirira huwandu hwe choline muropa neuropi. Zvidzidzo zvakawanda zvakasimbisa mabhenefiti akasiyana-siyana eAlpha-GPC uye zvakaratidza kuti kuwedzerwa kwemukanwa kunogona kuita basa rakakosha mukusimudzira mashandiro etsinga, mashandiro emuviri, uye kuvandudza ndangariro.

Kushanda kweAlpha-GPC

Wedzera simba rehuropi

Kuwanda kwemasero etsinga muuropi, ndiko kusimba kwaanoita, uye kukurumidza kwawo kutumira zviratidzo zvetsinga, uye simba reuropi rekugadzirisa rinosimba. Alpha-GPC inogona kuvandudza kushanda kwehuropi zvakakwana nekuwedzera simba remasero etsinga uye kugona kwekutumira zviratidzo zvetsinga. Panyaya yekuwedzera cholinergic neurotransmission, kutumira zviratidzo pakati pemasero etsinga kunoenderana nekutumira kwe neurotransmitters, uye acetylcholine chinhu chakakosha chemakemikari chinotuma uye neurotransmitter chinoita kuti kufunga kushande uye kuchengetedza kubatana pakati pehuropi nemuviri wese. Alpha-GPC inogona kupatsanurwa kuita 3-glycerol phosphate necholine muuropi uye ndiyo inonyanya kushanda yeacetylcholine. Inogona kusimudzira ndangariro nekuvandudza kufunga nekusimudzira kugadzirwa nekuburitswa kweacetylcholine muuropi. Panyaya yekuwedzera kugadzikana nekuyerera kwemasero, Alpha-GPC inogona kukurudzira kugadzirwa kwephosphoinositide, nokudaro ichisimudzira kugadzikana nekuyerera kwemasero. MaNeuron ane chimiro chakakwana anogona kuendesa ruzivo zviri nani nekuvandudza kugona kwekufunga kwemuviri. Shandisa.

Dzivirira tsinga

Zvinhu zvinokura mutsinga dzetsinga, zvinoti neurotrophic factors, zvinogona kudzora kusiyanisa kwemasero ekutanga uye kukurudzira kuumbwa kwekubatana kutsva kwetsinga. Alpha-GPC inogona kukurudzira kuburitswa kwezvinhu zvakasiyana-siyana zvetsinga uye kumutsa nzira dzekutumira zviratidzo zvine chekuita nekurarama kwemasero, nokudaro ichiita kuti tsinga dzidzivirire. Kuvandudza huwandu hwepfungwa dzemuviri. Panguva imwe chete, Alpha-GPC inogonawo kukurudzira kuburitswa kwehomoni yekukura uye kuchengetedza hutano hwemuviri nekuwedzera huwandu hwehomoni yekukura mumuviri.

Antioxidant

Kuoxidation nekuzvimba ndizvo zvinonyanya kukonzera kukwegura nekufa kwemasero europi. Alpha-GPC inogona kubvisa ma free radicals mumuviri, kurwisa oxidative stress, uye inogonawo kuderedza kuzvimba kwakadai se nuclear factor NF-κB, tumor necrosis factor TNF-α, uye interleukin IL-6. Kuburitswa kwezvinhu kunodzivirira kuzvimba kweuropi, nokudaro kuchidzosera shure zvakanyanya kudzikira kwebasa repfungwa uye kudzivirira kuitika nekukura kwezvirwere zvinokanganisa tsinga. Mhedzisiro yakakosha yatsigirwa nemigumisiro yekiriniki.

Muchidzidzo chinonzi "Mhedzisiro yeAlpha-GPC paKukanganisika Kwendangariro Kunokonzerwa Nezera", vanhu vana vakapihwa placebo, uye vamwe vanhu vashanu vakapihwa Alpha-GPC (1200 mg/zuva), mushure mekunwa nguva dzose kwemwedzi mitatu, maelectrode gumi nematanhatu akashandiswa kunyora mafungu europi kwemaminitsi mashanu vanhu vacho pavakanga vakamuka uye vachizorora. Mhedzisiro yacho yakaratidza kuti kana ichienzaniswa neplacebo, Alpha-GPC yakakwanisa kuwedzera zvakanyanya huwandu hwemafungu europi anokurumidza, ukuwo iine tsika yekuderedza mafrequency anononoka. Kureva kuti, inogona kuwedzera simba reuropi revanhu vezera repakati uye kunonotsa kukwegura kwemuviri.

Gadzirisa manzwiro

Dopamine inogona kuita kuti vanhu vafare, uye serotonin ne gamma-aminobutyric acid zvinogona kudzora mafungiro emuviri. Alpha-GPC inogona kukurudzira kuburitswa kwedopamine, kuwedzera kutaura kwe dopamine transporters, kuvandudza dopamine neurotransmission muuropi, uye kuwedzera huwandu hwe serotonin mu striatum ne prefrontal cortex; inogonawo kukurudzira zvakanyanya γ- Kuburitswa kwe aminobutyric acid kunoderedza kushaya hope, nokudaro ichishandisa mhedzisiro yayo yekurwisa kuora mwoyo, kuderedza kuzvidya mwoyo uye kugadzirisa mafungiro.

Pamusoro pezvo, Alpha-GPC inoita seyakakwanisawo kuwedzera kupinza kwesimbi isiri-heme muchikafu, zvakafanana nekushanda kwevhitamini C pachiyero che2:1 nesimbi, saka Alpha-GPC inoonekwa se, kana kuti inobatsirawo, kuwedzera kwezvigadzirwa zvenyama. Chiitiko chekupinza simbi isiri-heme. Pamusoro pezvo, kuwedzera neAlpha-GPC kunogonawo kubatsira maitiro ekupisa mafuta uye kutsigira metabolism yemafuta. Izvi zvinokonzerwa nebasa recholine sechikafu chinopa mafuta akawanda. Hutano hwechikafu ichi hunoita kuti mafuta acids awaneke kumasero emitochondria, ayo anogona kushandura mafuta aya kuita ATP kana simba.

Zvigadziriso zvemitemo

Alpha GPC yave ichishandiswa kwemakore anopfuura gumi. Parizvino, Alpha GPC imhando itsva yechikafu muJapan uye inowanzo shandiswa mukugadzira chikafu chinoshanda. Pamusoro pezvo, United States, Canada, Switzerland nedzimwe nyika dzakabvumidza kana kubvumidza Alpha GPC kuwedzerwa kune chikafu mushure meJapan. MuUnited States, Alpha GPC inotongwa seChinhu Chinozivikanwa Sechisina Kukuvara (GRAS). MuCanada, Alpha GPC inotenderwa sechigadzirwa chehutano chechisikigo.

Mashandisirwo emusika uye mafambiro ezvigadzirwa

Tichifunga nezve data risina kukwana pamusoro pekuchengetedzeka kweAlpha GPC muvacheche, vakadzi vane pamuviri, uye vakadzi vanoyamwisa, zvichibva papfungwa yekudzivirira njodzi, mapoka ari pamusoro apa haafanire kuidya, uye chinyorwa nemirairo zvinofanirwa kuratidza boka risingakodzeri. MuUnited States, Japan, Canada nedzimwe nyika, Alpha GPC yave ichishandiswa zvakanyanya mukudya. Zvigadzirwa zvine chekuita nazvo zvinofukidza zvekudya zvinovaka muviri, zvinwiwa, gummies nezvimwe zvikamu, uye chigadzirwa chega chega chine basa rakajeka uye chinokurudzirwa kushandiswa.

Huwandu nemapoka anokurudzirwa. Semuenzaniso, muUnited States, kune mishonga yekuwedzera inodarika mazana matatu yeAlpha GPC chete, ine mhedzisiro inosanganisira kuvandudza ndangariro nekushanda kwepfungwa, kuvandudza mashandiro emuviri, nezvimwewo. Chiyero chezuva nezuva i300-1200 mg.
Mamiriro azvino etekinoroji yekugadzira

Tsvagiridzo inoratidza kuti kugadzira makemikari ndeimwe yenzira huru dzekugadzira Alpha GPC. Uchishandisa polyphosphoric acid, choline chloride, R-3-chloro-1,2-propanediol, sodium hydroxide nemvura sezvinhu zvakabikwa, mushure mekusanganiswa kwemvura uye esterification reaction, inobviswa ruvara, tsvina inobviswa, inonatswa, inonatswa uye inoomeswa. inogona kuwanikwa nedzimwe nzira. Zvisinei, kugadzira makemikari echinyakare, makemikari hydrolysis, makemikari alcoholysis nedzimwe nzira dzese dzinosangana nematambudziko akadai sekusvibiswa kwezvakatipoteredza, mitengo yakakwira, uye maitiro akaoma ekugadzirira.

Mumakore achangopfuura, kugadzirira kweAlpha GPC nenzira dzebioenzyme kwave kuchiwedzera kutariswa. Nzira dzeAqueous-phase enzymatic, nzira dzenon-aqueous-phase enzymatic, nezvimwewo zvakabuda imwe mushure meimwe. Zvichienzaniswa nenzira dzemakemikari, kugadzirira kweAlpha GPC nenzira dzebioenzyme kune mamiriro ekuita zvinyoro uye maitiro ari nyore. , kushanda zvakanaka kwecatalytic uye kwakakodzera kugadzirwa kukuru kwekutengeserana.

Suzhou Myland Pharm & Nutrition Inc. ikambani yakanyoreswa neFDA inopa Alpha GPC Supplement powder yemhando yepamusoro uye yakachena.

KuSuzhou Myland Pharm takazvipira kupa zvigadzirwa zvemhando yepamusoro nemitengo yepamusoro. Upfu hwedu hweAlpha GPC Supplement hwakaedzwa zvakasimba kuti huve hwakachena uye hune simba, zvichiita kuti uwane supplement yemhando yepamusoro yaunogona kuvimba nayo. Kunyangwe uchida kutsigira hutano hwemasero, kusimbisa masoja emuviri wako kana kusimudzira hutano hwese, upfu hwedu hweAlpha GPC Supplement ndiyo sarudzo yakakwana.

Nemakore makumi matatu eruzivo uye zvichitungamirirwa netekinoroji yepamusoro uye nzira dzeR&D dzakanyatsogadzirwa, Suzhou Myland Pharm yakagadzira zvigadzirwa zvakasiyana-siyana zvinokwikwidzana uye yakava kambani itsva yekuwedzera sainzi yehupenyu, kugadzira zvinhu zvakagadzirwa uye kugadzira zvinhu.

Pamusoro pezvo, Suzhou Myland Pharm ikambani yakanyoreswa neFDA. Zvishandiso zveR&D zvekambani, nzvimbo dzekugadzira, uye zvishandiso zvekuongorora ndezvemazuva ano uye zvinoshanda zvakawanda, uye zvinogona kugadzira makemikari kubva pamamirigiramu kusvika kumatani muhukuru, uye zvinoenderana neISO 9001 standards uye specifications dzekugadzira GMP.

Alpha GPC inozivikanwa nekushanda kwayo zvakanaka, zvichireva kuti inonwisa hunyoro kubva mumhepo yakapoteredza. Nekuda kweizvi, mishonga yekuwedzera inofanira kuchengetwa mumidziyo isingapindi mhepo uye haifanirwe kuiswa mumhepo kwenguva yakareba.

Pfungwa dzekupedzisira

Alpha GPC inoshandiswa kuendesa choline kuuropi kuburikidza neropa-uropi. Ndiyo inotangira acetylcholine, neurotransmitter inosimudzira hutano hwepfungwa. Mishonga yekuwedzera yeAlpha GPC inogona kushandiswa kubatsira hutano hwako hwepfungwa nekuvandudza ndangariro, kudzidza, uye kutarisisa. Tsvagiridzo inoratidzawo kuti Alpha GPC inobatsira kuwedzera simba remuviri uye simba retsandanyama.