Kugona kwekuziva kunoreva kugona kwemunhu kugadzirisa ruzivo, kurangarira, kudzidza, kunzwisisa nekugadzirisa matambudziko.Chinhu chakakosha uye chakakosha kuti munhu abudirire pabasa uye muhupenyu.Kukanganisa kwemaitiro ekuvandudza kugona kwekuziva kune zvakakosha pakubudirira kwemunhu uye kugara zvakanaka.
Munguva ino yeruzivo, tinofanira kugamuchira ruzivo rwakawanda zuva rega rega.Uropi haudi chete kugamuchira ruzivo, asiwo kugadzirisa uye kunyora ruzivo.Pasi pebasa rakasimba zvakadaro, zvinodikanwa kuvandudza kugona kwehuropi.Kuwedzeredza kwekuziva kunogona kubatsira vanhu kuvandudza ndangariro, zvese zvenguva pfupi uye kwenguva refu.Iwe unokwanisa zvirinani kuyeuka uye kuyeuka ruzivo, kuvandudza kudzidza nekubudirira.
Kubva pamaonero esainzi, kugona kwekuziva ipfungwa yakagadzikana, asi tsvakiridzo inoratidza kuti vanhu vanogona kuvandudza kugona kwavo kwekuziva kuburikidza nemamwe mazano uye kudzidziswa.Izvi zvakakosha nekuti zvinoreva kuti isu hatifanirwe kuve nerumwe hunyanzvi hwekuziva, asi kuti isu tinogona kushingaira kuvandudza kuburikidza nezviito zvekuziva.
Saka, chii chaizvo chinonzi Pramiracetam?Pramiracetam inhengo yekugadzira iyo ndeyemhuri yevatambi.Pramiracetam yakagadzirwa muZ1970s uye yakadzidzwa zvakanyanya nekuda kwekuziva kwayo-kunatsiridza zvivakwa.Zvinotendwa kuti zvinoshanda nekukurudzira chaiwo mareceptor muuropi ane chekuita nekudzidza uye ndangariro maitiro, nekudaro kuvandudza kwese kwekuziva basa.
Pramiracetam inowedzera kuumbwa kwendangariro uye kudzoreredza.Zvidzidzo zvakaratidza kuti pramiracetaminogona kuvandudza zvakanyanya ndangariro dzenguva pfupi uye dzenguva refu.Izvi zvinonyanya kubatsira kuvadzidzi uye vanhu vari kutsvaga kuvandudza kugona kwavo kwese kwekuziva.
Uyewo inovandudza kuisa pfungwa uye kutarisa.Vazhinji vashandisi vanotaura kuti Pramiracetam inovabatsira kuti varambe vakangwarira uye vakatarisa kwenguva yakareba, zvichiita kuti zvive zvakanaka kune vanhu vanoda kunyanya kuisa pfungwa pabasa kana kuchikoro.
Zvinonzi zvinosimudzira kugona kwemunhu kufunga zvakajeka, kugadzirisa ruzivo nekukurumidza, uye kugadzira kubatanidza zvine musoro.Izvi zvinogona kunge zvakakonzerwa nemigumisiro yePramiracetam pane acetylcholine receptors muuropi, neurotransmitter inoita basa rinokosha mukugadzirisa mafungiro.
Dzidza nezve Pramiracetam:
Pramiracetam inogadzirwa kubva kumhuri yedzinza inozivikanwa nekuziva kwayo-kunatsiridza zvivakwa.Iyo inonyanya kutariswa seimwe yeakanyanya simba uye ane simba nootropics, akagadzirirwa kusimudzira ndangariro, kutarisisa, uye yakazara cognitive basa.
Efficacy uye Benefits:
Tsvakurudzo dzinoverengeka dzakaongorora kushanda kwePramiracetam, ichiratidza zvingangobatsira zvekuziva.Chidzidzo chakakurumbira chakabudiswa mu Journal of Psychopharmacology chakashuma kuti Pramiracetam yakavandudza chiyeuchidzo nekudzidza muvanhu vane hutano.Vatori vechikamu vakabatwa nePramiracetam vakaratidza kuvandudzwa kukuru mumabasa ekuyeuka, kugadzirisa pfungwa, uye kuchengetwa kwenguva refu kwekuyeuka.
Pamusoro pezvo, Pramiracetam inofungidzirwa kuwedzera ndangariro yekushanda, iyo yakakosha kumabasa anoda kutarisisa uye kukurumidza kwepfungwa.Nekukurudzira kusunungurwa uye kutora kweacetylcholine, neurotransmitter inokosha kukuyeuka nekudzidza, Pramiracetam yakaratidzwa kuti iwedzere kushanda kwekuziva kune vanhu vane kukanganisa kwekuyeuka.
Pamusoro pezvo, Pramiracetam inowanzo pihwa kune yayo neuroprotective zvimiro.Inofungidzirwa kuti iyi nootropic inowedzera kushandiswa kweokisijeni uye glucose metabolism muuropi, nokudaro inovandudza hutano hwehuropi nekudzivirira kuderera kwekuziva.
Mechanism:
Iyo chaiyo nzira yekuita iyo Pramiracetam inoshandisa kugadzirisa kwayo-inosimudzira mhedzisiro haina kunyatsonzwisiswa.Nekudaro, inofungidzirwa kudzora ese ari maviri cholinergic uye glutamatergic masisitimu, ese ari maviri anoita mabasa akakosha mukuziva basa.
Cholinergic regulation inosanganisira kusunungurwa uye kutora kweacetylcholine, neurotransmitter inokonzera kuumbwa kwekuyeuka uye kubatanidzwa.Nokuwedzera kuwanikwa kweacetylcholine, pramiracetam inofungidzirwa kuti inokurudzira synaptic siginecha, nokudaro ichikurudzira kuwedzera kudzidza nekuyeuka.
Glutamate regulation, kune rumwe rutivi, inobatanidzwa nekugadzirisa kwekunakidza neurotransmission.Pramiracetam inofungidzirwa kuti inowedzera glutamate, iyo inokurudzira kuvandudzwa kwe synaptic plasticity uye huropi hwose hunoita basa.
Munyika yekuvandudza kwekuziva uye nootropic zvinodhaka, pramiracetam uye piracetam zvinhu zviviri zvakakurumbira zvinowanzoba chiratidziro.Mishonga iyi ndeyeboka remishonga yekugadzira inozivikanwa sema racemates, inozivikanwa nekugona kwavo kugona-kunatsiridza mhedzisiro.Ose ari maviri Pramiracetam uye piracetam mishonga ye nootropic inosimudzira kushanda kwehuropi, inovandudza chiyeuchidzo, inosimudzira kutarisa, uye inovandudza kugona kwekuziva.Zvisinei, pasinei nekufanana, pane zvimwe zvakasiyana zvakasiyana pakati pezvinhu zviviri izvi.
1. Kemikari yakagadzirwa:
Piracetam, mutangiri wemishonga yese yemujaho, yakawanikwa muma1960.Iyo inoumbwa neiyo pyrrolidone chimiro uye inhengo yekutanga yemhuri yedzinza.Pramiracetam, kune rumwe rutivi, inobva kune piracetam ine dipropan-2-ylaminoethyl boka rakawedzerwa kune chimiro chayo.Kuchinja kudiki uku kunoita kuti Pramiracetam ishande zvakanyanya kupfuura piracetam.
2. Kushanda uye chipimo chemushonga:
Panyaya ye potency, Pramiracetam inopfuura Piracetam.Inofungidzirwa kuva ine simba rakapetwa ka10 kusvika ku30 kupfuura rakaritangira.Nekuda kwesimba rayo rinowedzeredzwa, madhasi akaderera akawanda anodiwa kuPramiracetam kana ichienzaniswa nepiracetam.
3. Nzira yekuita:
Pramiracetam uye piracetam zvose zvinoshanda nekukanganisa cholinergic system muuropi.Izvo zvinokanganisa kugadzirwa uye kuita kwemaurotransmitters akadai seacetylcholine, iyo inoita basa rakakosha mukurangarira, kudzidza uye mamwe maitiro ekuziva.Zvisinei, Pramiracetam inofungidzirwa kuva nemigumisiro yakananga pa-high-affinity choline uptake (HACU) mu hippocampus, nharaunda yeuropi inotarisirwa kuumbwa kwechiyeuchidzo nekudzorera.Ichi chakasarudzika chiito chePramiracetam chinoita kuti chinyatsoshanda mukusimudzira ndangariro.
4. Kubatsira kwekuziva:
Ose ari maviri Pramiracetam uye piracetam ane akawanda mabhenefiti kana zvasvika pakuziva kwekusimudzira.Piracetam inowanzofarirwa nekukwanisa kwayo kuvandudza chiyeuchidzo, kuisa pfungwa, uye kuisa pfungwa.Iyo inozivikanwa zvakare kuwedzera kugona kwekuziva basa, zvichiita kuti ive yakanaka kune vanhu vari kutsvaga kusimudzira kushanda kwavo kwepfungwa kwese.Pramiracetam, kune rumwe rutivi, inonyanya kushanda pakusimudzira ndangariro dzenguva refu, kuvandudza kudzidza kwenzvimbo, uye kuwedzera kuisa pfungwa.
5. Zvinogona kuitika:
Pramiracetam uye piracetam zvinowanzoregirwa zvakanaka nechiitiko chakaderera chemhedzisiro.Zvisinei, mhinduro dzemunhu mumwe nemumwe dzinogona kusiyana.Zvinowanzoitika zvinogona kuitika zvinosanganisira musoro, matambudziko emudumbu, kutya, uye dzungu.Izvi zvinowanzova zvinyoro uye zvenguva pfupi, zvinopera apo muviri unogadzirisa kune chinhu.
Kana zvasvika pakuyerwa kwePramiracetam, zvinofanirwa kusimbiswa kuti makemikari emuviri wemunhu wega uye kushivirira zvinogona kusiyana.Naizvozvo, chipimo chemushonga chinogonawo kusiyana zvichienderana nezvinodiwa nemunhu uye zvinangwa.Kazhinji, muyero wezuva nezuva wePramiracetam unobva pa500 kusvika 1,200 mg wakakamurwa kuita maviri kana matatu madhizi zuva rese.
Inokurudzirwa kutanga neiyo yakaderera inoshanda dose uye zvishoma nezvishoma kuwedzera iyo kana zvichidikanwa.Uye ongorora mhinduro yemuviri wako.Kana pasina mhedzisiro inocherechedzwa inocherechedzwa, iyo dose inogona kugadziriswa kumusoro kuti ubvumire muviri wako nguva yekuchinja kune yega yega yega shanduko.
side effect:
Kunyange zvazvo Pramiracetam inowanzotenderwa zvakanaka, munhu anofanira kunge achiziva zvinogona kuitika.Zvinonzi mhedzisiro yePramiracetam ine unyoro uye isingawanzo, uye kazhinji inogadzirisa mushure mekuregedzwa kwekomboni.Izvi zvinogona kusanganisira:
●Musoro wemusoro: Musoro wakapfava ndiwo wakajairika mhedzisiro inosanganiswa nekushandiswa kwePramiracetam.Kuwedzera kudya kwecholine kuburikidza nezvokudya zvakadai semazai kana kushandisa choline supplements zvinogona kubatsira kuderedza izvi.
●Kushungurudzika kweGastrointestinal: Vamwe vashandisi vakashuma zviratidzo zvekugaya zvakadai sekusvotwa, kugumbuka mudumbu, kana manyoka.Kuita chokwadi chekuti unotora Pramiracetam nechikafu kunogona kubatsira kuderedza izvi.
●Kuvhiringidzika kwehope: Pramiracetam inogona kukonzera kuvhiringidzika kwehope sekushaya hope kana ikatorwa gare gare muzuva.Kuti udzivise izvi, zvinokurudzirwa kutora praracetam pakutanga kwezuva kana mangwanani.
●Kuzvidya mwoyo kana kukakavara: Muzviitiko zvisingawanzoitiki, munhu anogona kuwedzera kushushikana kana kushushikana.Kana ukaona zviratidzo izvi, zvinokurudzirwa kurega kushandisa uye kubvunza nyanzvi yezvehutano.
Mubvunzo: Zvinotora nguva yakareba sei kuti uwane migumisiro yePramiracetam?
A: Kutanga kwemigumisiro yePramiracetam inogona kusiyana kubva kumunhu kusvika kune munhu.Nepo vamwe vanhu vangatanga kuona mabhenefiti ayo mukati memaawa mashoma, vamwe vanogona kutora mazuva mashoma ekushandiswa nguva dzose kuti vaone kuvandudzwa kunooneka mukushanda kwekuziva.
Mubvunzo: Pramiracetam yakachengeteka kuti ishandiswe here?
A: Pramiracetam inowanzoonekwa yakachengeteka kuti ishandiswe kana inotorwa pachiyero chakakurudzirwa.Nekudaro, sekune chero chekuwedzera kana mushonga, zvinogara zvichikurudzirwa kubvunzana nenyanzvi yezvehutano usati watanga kushandiswa kwayo, kunyanya kana uine chero mamiriro ekurapa kana uri kutora mimwe mishonga.
Disclaimer: Ichi chinyorwa ndechezvinangwa zveruzivo chete uye hachifanirwe kutorwa sezano rekurapa.Nguva dzose bvunza nyanzvi yezvehutano usati washandisa chero chekuwedzera kana kushandura hutano hwehutano hwako.
Nguva yekutumira: Aug-11-2023
