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Pamusoro 4 Anti-Kuchembera Zvekuwedzera zveKuvandudza Mitochondrial Hutano: Ndeipi Yakasimba?

Masayendisiti akawana kuti sezvatinokura, mitochondria yedu inoderera zvishoma nezvishoma uye inogadzira simba shoma. Izvi zvinogona kutungamira kuzvirwere zvine chekuita nezera senge neurodegenerative chirwere, chirwere chemoyo, nezvimwe.

Urolithin A

Urolithin A yakasikwa metabolite ine antioxidant uye antiproliferative mhedzisiro. Nutritionists kubva kuNova Southeastern University muUnited States vakaona kuti kushandisa urolithin A sechikafu chinopindira kunogona kunonoka kukwegura uye kudzivirira kukura kwezvirwere zvine chokuita nezera.
Urolithin A (UA) inogadzirwa nemabhakitiriya emudumbu medu mushure mekudya ma polyphenols anowanikwa muzvikafu zvakaita semapomegranati, sitirobheri, uye walnuts. UA yekuwedzera kune mbeva dzepakati-kati inomutsa sirtuins uye inowedzera NAD + uye maserura simba mazinga. Zvakakosha, UA yakaratidzwa kujekesa mitochondria yakakuvadzwa kubva mumhasuru dzevanhu, nekudaro ichivandudza simba, kuramba kuneta, uye kuita kwemitambo. Naizvozvo, UA yekuwedzera inogona kuwedzera hupenyu nekurwisa kuchembera kwemhasuru.
Urolithin A haiuyi zvakananga kubva mukudya, asi makomisheni akadai se ellagic acid uye ellagitannins ari munzungu, mapomegranati, mazambiringa uye mamwe majiroji anoburitsa urolithin A mushure mekugadziriswa nehutachiona hwematumbo.

Spermidine

Spermidine imhando yechisikigo ye polyamine iyo yakagamuchira kutariswa mumakore achangopfuura nekuda kwekugona kwayo kuwedzera hupenyu uye kuwedzera hutano. Kufanana neNAD + neCoQ10, spermidine imorekuru rinongoitika rinodzikira nezera. Zvakafanana neUA, spermidine inogadzirwa nehutumbi hwedu hwemabhakitiriya uye inokonzera mitophagy - kubviswa kwemitochondria isina kunaka, yakakuvadzwa. Zvidzidzo zvembeva zvinoratidza kuti spermidine supplementation inogona kudzivirira kubva kuchirwere chemoyo uye kuchembera kwevakadzi. Uyezve, kudya spermidine (inowanikwa mune zvakasiyana-siyana zvekudya zvinosanganisira soy uye zviyo) yakavandudza chiyeuchidzo mumakonzo. Tsvagiridzo yakawanda inodiwa kuona kana zvakawanikwa izvi zvichigona kudzokororwa muvanhu.
Kuchembera kwakajairwa kunoderedza kuwanda kwemhando dzechisikigo dzespermidine mumuviri, sekureva kwetsvakiridzo yakaburitswa muScientific Reports nevatsvakurudzi veKyoto Prefectural University of Medicine muJapan. Zvisinei, chiitiko ichi hachina kuonekwa mumazana emakore;
Spermidine inogona kukurudzira autophagy.
Zvokudya zvine spermidine yakakwira zvinosanganisira: chikafu chegorosi, kelp, howa hweshiitake, nzungu, bracken, purslane, nezvimwe.

Iyo kambani Suzhou Myland Pharm & Nutrition Inc.

curcumin
Curcumin ndiyo inoshandiswa mu turmeric ine anti-inflammatory uye antioxidant properties.
Ongororo yebiologist kubva kuPolish Academy yeSainzi vakawana kuti curcumin inogona kuderedza zviratidzo zvekuchembera uye kunonoka kufambira mberi kwezvirwere zvine chekuita nezera umo masenescent masero anobatanidzwa zvakananga, nekudaro achiwedzera hupenyu.
Mukuwedzera kune turmeric, zvokudya zvakakwirira mu curcumin zvinosanganisira: ginger, garlic, hanyanisi, mhiripiri yakasviba, mustard uye curry.

NAD + zvinowedzera
Iko kune mitochondria, kune NAD + (nicotinamide adenine dinucleotide), molekuru inodiwa mukuwedzera kugadzirwa kwesimba. NAD + inodzikira nezera, zvinoita sekunge zvinoenderana nezera-ane hukama kuderera mumitochondrial basa. Ichi ndicho chimwe chezvikonzero nei NAD + boosters seNR (Nicotinamide Ribose) yakagadzirwa kudzoreredza NAD + mazinga.
Tsvagiridzo inoratidza kuti nekusimudzira NAD +, NR inogona kusimudzira kugadzirwa kwesimba remitochondrial uye kudzivirira kushushikana-kwezera. NAD + precursor supplements inogona kuvandudza kushanda kwemhasuru, hutano hwehuropi, uye metabolism uku uchikwanisa kurwisa zvirwere zveurourodegenerative. Pamusoro pezvo, ivo vanoderedza uremu, vanovandudza insulin senitivity, uye vanogadzirisa lipid mazinga, sekudzikisa LDL cholesterol.


Nguva yekutumira: Jul-24-2024