Evodiamine inhengo yakasikwa inowanikwa mumuchero weEvodiamine chirimwa, chinowanikwa kuChina nedzimwe nyika dzeAsia. Yakave ichishandiswa mumishonga yechinyakare yeChinese kwemazana emakore nekuda kwekugona kwayo hutano hunobatsira. Pakati pavo, evodiamine ine simba guru mukudzora kuzvimba uye kubatsira kuderedza uremu. Iyo inorwisa-kuzvimba zvimiro inoita kuti ive yakakosha mumiriri wekurapa dzakasiyana siyana zvirwere zvinoputika, nepo kugona kwayo kuwedzera thermogenesis uye kukurudzira lipolysis kunogona kubatsira mukuremerwa.
Wakambosangana neshoko rekuti "evodiamine" uye wakashamisika kuti rinorevei chaizvo? Evodiamine, inotorwa kubva muchirimwa Evodiamine, inhengo yakasikwa inowanikwa kuChina nedzimwe nyika dzeAsia. Evodiamine ndeyekirasi yealkaloids inozivikanwa se "quinazole alkaloids," mishonga inotorwa kubva mumichero isina kuibva yechirimwa uye inozivikanwa nemishonga yayo. Kwemazana emakore, mushonga wechinyakare weChinese wakashandisa simba re evodiamine kubvisa zvirwere zvakasiyana-siyana.
Evodiamine inozivikanwa neiyo thermogenic properties, maitiro ayo muviri unogadzira kupisa, izvo zvinogona kuwedzera metabolic rate uye kukurudzira kupisa kwemacalorie. Nokuwedzera thermogenesis, evodiamine inogona kubatsira kupisa mafuta uye kudzora uremu.
Kuzvimba ndiko kuzvidavirira kwemuviri pakukuvara kana kutapukirwa. Zvisinei, kuzvimba kusingaperi kunogona kukonzera zvirwere zvakasiyana-siyana. Nokuderedza kuzvimba, evodiamine inogona kubatsira kuvandudza hutano hwese uye kuderedza njodzi yezvimwe zvirwere.
Evodiamine inozivikanwa nokuda kwayo thermogenic properties. Thermogenesis inoreva maitiro ekugadzira kupisa mumuviri. Saka evodiamine inonyatso gadzira sei kupisa?
Imwe yenzira iyo evodiamine inoshandisa iyo thermogenic mhedzisiro ndeyekuita puroteni inonzi transient receptor inogona vanilloid subtype 1 (TRPV1). TRPV1 inonzi receptor inowanikwa kunyanya munheyo system uye inobatanidzwa mukugadzirisa kupisa kwemuviri uye metabolism. Apo evodiamine inosunga kuTRPV1, inokonzera mutsara wemhinduro dzepanyama, kusanganisira kuwedzera kwekushandisa simba uye thermogenesis.
Evodiamine yakawanikwa ichikurudzira adrenal glands kuburitsa catecholamines senge epinephrine uye norepinephrine. Macatecholamines anoita basa rakakosha mukuwedzera lipolysis, kuparara kwemafuta akachengetwa kuita emahara fatty acids anogona kushandiswa sechitubu chesimba. Iyi nzira inowedzera kukurudzira thermogenic mhedzisiro ye evodiamine.
Mukuwedzera, evodiamine yakaratidzwa kuti inodzivisa basa remamwe ma enzymes anobatanidzwa mukuumbwa nekuchengetedza kwemasero emafuta. Semuenzaniso, inodzivisa kutaura kweperoxisome proliferator-activated receptor gamma (PPARγ), chinhu chekunyora chinokurudzira kuunganidza mafuta muadipocytes. Nekudzivisa PPARγ basa, evodiamine inogona kubatsira kudzivirira kuumbwa kwemasero matsva emafuta uye kuderedza mafuta ekuchengetedza.
1. Kutarisira uremu
Imwe yezvinonyanya kuzivikanwa mabhenefiti evodiamine kugona kwayo seyakasikwa uremu rubatsiro. Tsvagiridzo inoratidza kuti evodiamine inogona kukurudzira "kupisa" receptors mumiviri yedu, inozivikanwa seyenguva pfupi yekugamuchira inogona kuva vanilloid 1 (TRPV1) receptors. Nekuita izvi zvinogamuchirwa, evodiamine inogona kubatsira kuwedzera thermogenesis uye mafuta oxidation, nekudaro ichiwedzera metabolism uye inogona kurasikirwa uremu. Uyezve, inodzivisa kukura kwemasero matsva emafuta, ichienderera mberi ichitsigira uremu hwekugadzirisa zvinhu.
2. Anti-inflammatory properties
Kuzvimba kusingaperi kwakabatana neakasiyana matambudziko ehutano, anosanganisira chirwere chemoyo, chirwere cheshuga, nezvimwe. Evodiamine inoonekwa seanogona anti-kuzvimba agent nekuda kwekugona kwayo kuvharidzira kugadzirwa kwepro-inflammatory molecules. Tsvakurudzo dzinoverengeka dzakaratidza kuti evodiamine inogona kudzivisa basa re nyukliya-κB (NF-κB), chinhu chinokosha chekunyora chinogadzirisa pro-inflammatory gene expression. Nekudzivisa NF-κB, evodiamine inoderedza kuputika nekuderedza kugadzirwa kwecytokines inoputika yakadai se interleukin-1β (IL-1β) uye tumor necrosis factor-α (TNF-α).
3. Analgesic uye analgesic properties
Marwadzo, anowanzobatanidzwa nekuzvimba, chimwe chiratidzo chakakosha chinogona kukanganisa zvakanyanya kunaka kwehupenyu. Iyo analgesic properties ye evodiamine yakadzidzwa zvakanyanya, nemhedzisiro inokurudzira. Tsvagiridzo inoratidza kuti evodiamine inogona kumisa iyo inononoka receptor inogona kuva vanilloid 1 (TRPV1) chiteshi, iyo inobatanidzwa mukufambiswa kwezviratidzo zvinorwadza. Nekuita zviteshi izvi, evodiamine inogona kuvharira manzwiro ekurwadziwa uye kupa zororo kune vanhu vane marudzi ese emarwadzo, kusanganisira neuropathic uye kurwadziwa kwekuzvimba.
4. Utano hwemwoyo
Kuchengetedza hutano hwemoyo system kwakakosha kune hutano hwese. Evodiamine yakaratidzwa kuva nemafungiro akanaka emwoyo, zvakadai sekuderedza hypertension uye inhibiting platelet aggregation. Nekuzorodza mitsipa yeropa nekudzivirira kugwamba kweropa kubva pakuumbwa, evodiamine inogona kubatsira kuvandudza kutenderera uye kuderedza njodzi yechirwere chemoyo, kusanganisira kurwisa kwemoyo uye sitiroko.
5. Hutano Hwematumbu
Evodiamine inogona kuve nemhedzisiro yakanaka pahutano hwematumbu nekusimudzira basa rekugaya uye kuderedza kusagadzikana kwegastrointestinal. Tsvagiridzo inoratidza kuti evodiamine inogona kukurudzira kuburitswa kwema enzymes ekugaya uye kuvandudza intestinal motility, pakupedzisira kubatsira kugaya uye kubvisa kusagadzikana kwekugaya. Pamusoro pezvo, evodiamine's inogona antimicrobial properties inogona kubatsira kurwisa mabhakitiriya anokuvadza uye kukurudzira hutano gut microbiome.
Evodiamine inodaidzwa kubva kune imwe yenzvimbo dzayo huru dzebhotani, Evodia rutaecarpa, inowanzo zivikanwa seEvodia muchero kana Evodia rutaecarpa. Chirimwa ichi chinobva kuEast Asia uye chave chichishandiswa mukurapa kwechiChinese kwemazana emakore. Zvibereko zvisina kuibva zveEvodia carota chirimwa ndicho chitubu chikuru che evodiamine. Ichi chishamiso chebhotani chine akawanda alkaloid, kusanganisira evodiamine, iyo yakaratidza mhedzisiro inobatsira pahutano.
Zvimwe zvinomera
Mukuwedzera kune Evodiamine, evodiamine inowanikwa mune dzimwe nzvimbo dzakawanda dzemiti. Izvi zvinosanganisira Alstonia macrophylla, Evodia lepta uye Euodia lepta, pakati pevamwe. Izvi zvinomera zvinozvarwa munzvimbo dzakasiyana dzeAsia, kusanganisira China, Japan, neThailand.
Sezvineiwo, aya botanical masosi haana kuganhurirwa kune imwe neimwe chikamu chechirimwa. Kunyange zvazvo michero isina kuibva ndiyo inonyanya kutangira, evodiamine inogonawo kutorwa kubva pamashizha, madzinde, uye midzi yemiti iyi. Izvi zvakasiyana-siyana zvezvinyorwa zvinopa vatsvakurudzi nemasayendisiti mikana yakawanda yekuongorora hutano hwakasiyana-siyana uye mashandisirwo evodiamine.
●Optimal dosage: Iyo yakakodzera dosi ye evodiamine inotsamira pane akati wandei zvinhu zvakaita sezera remushandisi, hutano, uye akati wandei mamwe mamiriro. Ramba uchifunga kuti zvigadzirwa zvechisikigo hazvisi nguva dzose zvakachengeteka, uye dosage nyaya. Zvakakosha kuti uverenge zvinyorwa zvechigadzirwa zvakanyatsonaka uye kubvunza nyanzvi yezvehutano kuti uone dosi inokodzera zvaunoda iwe pachako.
●Hutano Hwako Pamunhu: Pakusarudza kushandisa chero chekuwedzera, kusanganisira evodiamine, zvakakosha kufunga nezvehutano hwese hwemunhu, nhoroondo yekurapa, uye kushivirira kwake. Pamusoro pezvo, ziva nezvekudyidzana kwezvinodhaka uye funga nezvehutano hwemunhu kuti uwedzere mabhenefiti evodiamine uku uchidzikisa chero njodzi dzakabatana.
Mubvunzo: Evodiamine inobata sei kuzvimba?
A: Evodiamine yakawanikwa iine anti-inflammatory properties. Inodzivirira kuita kwemamwe mamorekuru anopisa, akadai senyukireya factor-kappa B (NF-kB) uye cyclooxygenase-2 (COX-2), iyo inoita basa rakakosha mukuzvimba. Nekudzikisa kugadzirwa kwemamorekuru aya, evodiamine inobatsira kuderedza kuzvimba mumuviri.
Mubvunzo: Evodiamine inogona kushandiswa kuderedza uremu here?
A: Evodiamine yakaongororwa nekuda kwezvinogona kuitika pakurasikirwa uremu. Zvinotendwa kuti zvinomutsa maitiro anonzi thermogenesis, ayo anowedzera tembiricha yepakati pemuviri uye mwero wemetabolism. Izvi, zvakare, zvinogona kuwedzera mari yekoriori uye kubatsira mukurasikirwa. Zvisinei, tsvakurudzo yakawanda inodiwa kusimbisa kushanda uye kuchengeteka kwe evodiamine yekurasikirwa nekurema.
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Nguva yekutumira: Sep-26-2023
