Kunzwisisa Urolithin A
Usati wanyatsoongorora basa rayo rinogona kuita mukuderedza uremu, zvakakosha kuti unzwisise maitiro uye zvimiro zveurolithin A. Iyi komputa yakasikwa inozivikanwa nekugona kwayo kuita mitophagy, nzira inobvisa yakakuvadzwa mitochondria kubva mumasero. Mitochondria inowanzonzi simba resero, ichiita basa rakakosha mukugadzira simba. Nekusimudzira mitophagy, urolithin A inobatsira kuchengetedza hutano hwemitochondrial uye basa, izvo zvakakosha kune yakazara cellular metabolism.
Urolithin A uye Weight Loss
Ongororo dzinoverengeka dzakaratidza kuti urolithin A inogona kuve nemhedzisiro yakanaka pakuremerwa kwehuremu. Imwe ongororo, yakabudiswa mupepanhau Nature Medicine, yakawana kuti urolithin A inogona kuvandudza mhasuru kushanda uye kutsungirira mumakonzo. Izvi zvakakosha nekuti kuwedzera kwemhasuru kushanda uye kutsungirira kunogona kubatsira kune yakakwira metabolic rate, inogona kubatsira mukurasikirwa nekurema.
Uyezve, urolithin A yakaratidzwa kuwedzera mafuta metabolism uye kuderedza kuunganidzwa kwemafuta mune adipose tissue. Chidzidzo chakabudiswa mupepanhau Nature Metabolism chakaratidza kuti urolithin A supplementation yakakonzera kudzikiswa kwemafuta emuviri uye kuvandudza metabolic paramita mumakonzo akafuta. Izvi zvakawanikwa zvinoratidza kuti urolithin A inogona kuita basa mukudzora lipid metabolism uye kukurudzira hutano hwemuviri kuumbwa.
Zvidzidzo zvevanhu uye Tsvakurudzo yeramangwana
Kunyange zvazvo humbowo hunobva kuzvidzidzo zvemhuka huri kuvimbisa, tsvakurudzo yevanhu pamusoro pemigumisiro yeurolithin A pakuderedza uremu ichiri shoma. Zvakadaro, ongororo yekiriniki yakaitwa nevaongorori vepa École Polytechnique Fédérale de Lausanne (EPFL) muSwitzerland yakapa nzwisiso yezvainogoneka. Muedzo wacho waisanganisira vanhu vakafuta uye vakafutisa vakapihwa urolithin A yekuwedzera kwemwedzi mina. Zvigumisiro zvakaratidza kuti urolithin A supplementation yakabatanidzwa nekuderedza uremu hwemuviri uye chiuno chechiuno, pamwe nekuvandudzwa kwezviratidzo zvehutano hwemagetsi.
Kunyangwe izvi zvinokurudzira zvakawanikwa, kumwe kutsvagisa kunodiwa kuti unzwisise zvizere kukanganisa kweurolithin A pakurasikirwa nehuremu muvanhu. Zvidzidzo zvenguva yemberi zvinofanirwa kuongorora nzira dzayo dzekuita, yakakwana dosage, uye mhedzisiro yenguva refu pakuumbwa kwemuviri uye metabolism.
Chii chinobatsira cheurolithin A?
Imwe yemabhenefiti anonyanya kuzivikanwa eurolithin A ibasa rayo mukusimudzira hutano hwemitochondrial. Mitochondria ndiyo simba remasero edu, ane basa rekugadzira simba uye kuchengetedza cellular basa. Sezvo isu tichikura, kushanda zvakanaka kwemitochondria yedu kunodzikira, zvichitungamira kune dzakasiyana siyana dzine chekuita nenyaya dzehutano. Urolithin A yakawanikwa kuwedzera mitochondrial biogenesis, maitiro ekugadzira mitochondria itsva, uye kuvandudza basa ravo. Nekutsigira hutano hwemitochondrial, urolithin A inogona kubatsira kuhuwandu hwesimba, kuita kwemuviri, uye hupenyu hurefu.
Uyezve, urolithin A inoratidza yakasimba anti-inflammatory properties. Kuzvimba kusingaperi kwakabatana neakawanda hutano mamiriro, kusanganisira chirwere chemoyo, chirwere cheshuga, uye neurodegenerative kusagadzikana. Zvidzidzo zvakaratidza kuti urolithin A inogona kubatsira kuenzanisa nzira dzekuzvimba, kuderedza kugadzirwa kwemamorekuru e-pro-inflammatory uye kusimudzira mhinduro yakaringana yekudzivirira. Nekudzikisa kuzvimba kusingaperi, urolithin A inogona kubatsira mukudzivirira uye manejimendi ezvirwere zvine chekuita nekuzvimba.
Pamusoro pemhedzisiro yayo pamitochondrial uye hutano hwekuzvimba, urolithin A yakaratidza chivimbiso mukutsigira mhasuru kushanda uye kupora. Tsvagiridzo inoratidza kuti urolithin A inogona kuwedzera tsandanyama kupararira uye mapuroteni synthesis, ayo akakosha mukukura kwemhasuru uye kugadzirisa. Izvi zvine zvazvinoreva kune vatambi uye vanhu vari kutsvaga kuchengetedza mhasuru uye simba, kunyanya pavanenge vachikura. Uyezve, urolithin A inogona kubatsira mukudzoreredza mushure mekuita kurovedza muviri kwakasimba, zvichigona kuderedza kukuvara kwemhasuru uye kukurumidza kupora tsandanyama.
Imwe bhenefiti inonakidza yeurolithin A ibasa rayo rinogona kuita mukusimudzira hutano hwematumbo. Iyo gut microbiota inoita basa rakakosha mukuchengetedza hutano hwese, kupesvedzera kugaya, immune function, uye kunyangwe kugara zvakanaka kwepfungwa. Urolithin A yakaratidzwa kuva ne prebiotic-semhedzisiro, zvichireva kuti inogona kusarudza kusimudzira kukura kwebhakitiriya inobatsira mumatumbo. Nekutsigira hutano gut microbiota, urolithin A inogona kubatsira mukuvandudza kugaya, basa rekudzivirira muviri, uye chiyero chese chemukati megut ecosystem.
Zvakare, tsvakiridzo iri kubuda inoratidza kuti urolithin A inogona kunge iine neuroprotective zvivakwa, ichipa zvingangobatsira zvehutano hwehuropi. Zvidzidzo zvakaratidza kuti urolithin A inogona kubatsira kubvisa yakakuvara kana kusashanda mitochondria mumasero europi, maitiro anozivikanwa semitophagy. Izvi zvinogona kuve nezvazvinoreva kune neurodegenerative mamiriro akadai seAlzheimer's neParkinson's hosha, uko kusashanda zvakanaka kwemitochondrial kunoita basa rakakura.
Ndeipi nguva yezuva yandinofanira kutora urolithin A?
Mubvunzo mumwe wakajairika unomuka pakati pevanhu vari kutsvaga kuisa urolithin A muhupenyu hwavo hwezuva nezuva ndewekuti, "Inguva ipi yezuva yandinofanira kutora urolithin A?"
Nepo pasina-saizi-inokodzera-yese mhinduro kumubvunzo uyu, pane zvimwe zvinhu zvekufunga nezvazvo pakusarudza nguva yakanakisa yekutora urolithin A kuti uwane mabhenefiti akawanda. Chimwe chinhu chakakosha chekufunga nezvacho ndeye bioavailability yeurolithin A, iyo inoreva kugona kwemuviri kutora uye kushandisa musanganiswa nemazvo. Tsvagiridzo inoratidza kuti urolithin A inotorwa zvakanyanya kana yakatorwa nechikafu chine mamwe mafuta, sezvo izvi zvichigona kuwedzera bioavailability yayo.
Nezve nguva, dzimwe nyanzvi dzinokurudzira kutora urolithin A mangwanani nekudya kwemangwanani. Izvi zvinogona kubatsira kuve nechokwadi chekuti komisheni inonyudzwa zvine mutsindo uye inogona kupa kuwedzera kwesimba remaserura kutanga zuva. Pamusoro pezvo, kutora urolithin A mangwanani kunogona kubatsira kutsigira kupora kwemhasuru uye kuita kwese kwemuviri, zvichiita kuti ive sarudzo yakanaka kune vanhu vari kushingaira kana kuita maekisesaizi nguva dzose.
Kune rimwe divi, vamwe vanhu vangasarudza kutora urolithin A manheru, sechikamu chemaitiro avo ehusiku. Izvi zvinogona kubatsira mukusimudzira kugadziridzwa kweserura uye kuvandudzwa panguva yekuzorora kwemuviri uye nguva yekupora. Kutora urolithin A manheru, kunogona kutsigira maitiro emuviri ekucheneswa uye kuvandudzwa, zvichikonzera hutano hwesero uye hupenyu hurefu.
Pakupedzisira, nguva yakanakisa yekutora urolithin A inogona kusiyana zvichienderana nezvido zvemunhu uye mararamiro. Zvakakosha kufunga nezvemaitiro emunhu, madyiro, uye chero zvinangwa zvehutano zvakanangana paunenge uchisarudza nguva yakakodzera yekubatanidza urolithin A muchirongwa chezuva nezuva. Kubvunzana nenyanzvi yezvehutano kana mupi ane ruzivo anogonawo kupa gwara remunhu pane yakakwana nguva yekutora urolithin A kuti iwedzere mabhenefiti ayo.
Ndiani asingafaniri kutora urolithin A?
Vakadzi vane pamuviri uye vanoyamwisa vanofanira kudzivisa urolithin A yekuwedzera, sezvo pane tsvakurudzo shoma pamusoro pemigumisiro yayo panguva yekuzvitakura uye lactation. Zvinogara zvakanaka kukanganisa kudivi rekuchenjerera uye kubvunza nyanzvi yezvehutano usati watora chero chitsva chekuwedzera munguva dzino dzakaoma.
Vanhu vane allergies anozivikanwa kana kusanzwa kune urolithin A kana makomisheni ane hukama vanofanirawo kurega kutora urolithin A yekuwedzera. Allergic reactions inogona kubva kune yakapfava kusvika kune yakanyanya, saka zvakakosha kuti uzive chero zvingangoita allergenic mukuwedzera.
Vanhu vane zvirwere zvehutano, kunyanya avo vane chokuita neitsvo kana chiropa, vanofanira kutaurirana nemutarisiri wavo wehutano vasati vatora urolithin A. Sezvo urolithin A inogadziriswa muchiropa uye inobudiswa kuburikidza neitsvo, vanhu vane chiropa chisina simba kana kushanda kwetsvo vangada. dzivisa kana kunyatso tarisa kutora kwavo urolithin A kudzivirira chero matambudziko anogona kuitika.
Pamusoro pezvo, vanhu vari kutora mishonga kana zvimwe zvekuwedzera vanofanirwa kutsvaga nhungamiro kubva kunyanzvi yezvehutano vasati vawedzera urolithin A kuchirongwa chavo. Pane mukana wekudyidzana pakati peurolithin A nemimwe mishonga kana zvekuwedzera, saka zvakakosha kuve nechokwadi kuti hapana mhedzisiro yakaipa kana kuderedza kushanda kwemamwe marapirwo.
Nguva yekutumira: Jul-26-2024
