Zita resainzi reNAD ndinicotinamide adenine dinucleotide. NAD + iripo musero rega rega remuviri wedu. Iyo yakakosha metabolite uye coenzyme munzira dzakasiyana dzemetabolism. Inopindirana uye inobatanidzwa mune zvakasiyana-siyana zvehupenyu. Anopfuura mazana matatu ma enzymes anoenderana neNAD+ Kushanda. Nekudaro, iyo yemukati nhanho yeNAD + haina kumira. Sezvo isu tichikura, zvirimo zveNAD + mumaseru zvinodzikira. Kunyanya mushure mezera remakumi matatu, mwero weNAD+ uchadonha zvakanyanya, zvichikonzera kudzikira kwemabasa mazhinji nekudaro kuratidza zviratidzo zvekuchembera. Nicotinamide riboside chloride imhando yevhitamini B3. Nicotinamide riboside chloride inogona kushandurwa kuita NAD+ (nicotinamide adenine dinucleotide). Ndiyo imwe yeakanyanya kudzidzwa NAD + precursors. Inotorwa nyore nyore nemuviri uye kushandiswa. Zvidzidzo zvakawanda zvakaratidza kuti kuwedzera NRC kunogona kuwedzera NAD + mazinga, ayo anogona kuunza mabhenefiti kune metabolic, moyo uye tsinga masisitimu. Inowanzoshandiswa sechikafu chekuwedzera kusimudzira hutano hwese uye hutano.
Nicotinamide riboside chloride (NRC) inobva pavhitamini B3 uye chinhu chitsva chebioactive. Inoumbwa neshuga molecule ribose uye vhitamini B3 chikamu nicotinamide (inozivikanwawo se nicotinic acid kana vhitamini B3). Inogona kudyiwa kuburikidza nekudya nyama, hove, zviyo uye zvimwe zvekudya kana kuburikidza neNRC zvinowedzera.
Nicotinamide ribose chloride inogona kushandurwa kuita NAD+ (nicotinamide adenine dinucleotide) uye kuita biological chiitiko mukati memasero. NAD + yakakosha intracellular coenzyme inotora chikamu mune dzakasiyana siyana cellular metabolic maitiro, anosanganisira kugadzirwa kwesimba, DNA kugadzirisa, kupararira kwesero, etc. Munguva yekukwegura kwemuviri wemunhu, zvirimo muNAD + zvishoma nezvishoma zvinodzikira. Nicotinamide riboside chloride supplementation inogona kuwedzera mwero weNAD +, iyo inotarisirwa kunonoka kuitika kwekuchembera kwesero uye zvirwere zvinoenderana.
Tsvagiridzo yenicotinamide riboside chloride yakaratidza kuti ine zvakawanda zvipenyu zviitiko, senge:
Kuvandudza simba remetabolism, kuwedzera kutsungirira uye kurovedza muviri;
Kuvandudza basa retsinga uye ndangariro;
Kuvandudza immune system basa.
Pakazere, nicotinamide riboside chloride chinhu chinovimbisa chekudyara chikafu chine tarisiro yekushandiswa kwakafara.
Pamusoro pezvo, nicotinamide ribose chloride inoshandiswawo zvakanyanya mukutsvagisa kwesainzi. Sechinhu chinotangira cheNAD +, chinogona kushandiswa kudzidza iyo biosynthesis uye metabolic nzira dzeNAD + nezvimwe zvine hukama. Panguva imwecheteyo, nicotinamide riboside chloride inoshandiswawo sechinhu muzvigadzirwa zvehutano uye zvizorwa kusimudzira hutano hwesero uye kuderedza kuchembera kweganda.
Kuchembera inyaya isingaperi kuvanhu. Zvinoenderana nekutsvagisa kwakaitwa nemasaenzi, kuchembera kwesero kune hukama zvakanyanya nekudzikiswa kwenicotinamide adenine dinucleotide (NAD) zvirimo. NAD chinongedzo chakakosha mumetabolism uye kugadzirisa masero mumuviri wemunhu. Haikwanise kunonoka kuchembera chete, asi zvakare kuchengetedza hutano hwesero uye kuchengetedza hutano hwemuviri nepfungwa. asi. Sezvo isu tichikura, mazinga eNAD mumiviri yedu anodzikira nekukurumidza uye nekukurumidza, uye anogona kutodonha neinopfuura hafu pakati pemakore makumi mana ne80.
Kune enzyme yakakosha mumuviri wedu, inova ndiyo yakakosha chikamu cheserura simba metabolism. Kwakakosha sei? Anenge ese maitiro anochengetedza kushanda kwakajairika kwemuviri, senge metabolism, kugadzirisa, uye kusadzivirirwa, zvinoda kutora chikamu kweiyo enzyme. Apo mazinga e enzyme iyi anoderera, zviratidzo zvakawanda uye zvirwere zvinosangana nekukwegura zvinogona kuitika, zvakadai sezvirwere zvemagetsi, kushaya simba kwekudzivirira muviri, kuderera kwekuziva, etc. Iyi enzyme inokosha ine zita refu: nicotinamide adenine dinucleotide, kana NAD +.
Muchidimbu, kudzikiswa kweNAD + mumuviri kunoreva kuchembera. Saka, isu tinogona here kuwedzera NAD + kumuviri kunonoka kuchembera? Kana iwe ukawedzera zvakananga NAD +, muviri wemunhu hauzokwanisa kuutora, uye uchave nemhedzisiro yakaipa. Naizvozvo, vanhu vakatendeudzira pfungwa dzavo kune inotangira zvinhu zveNAD +: nicotinamide ribose chloride (NRC).
Nicotinamide riboside chloride imhando yevhitamini B3 uye imwe yeakanyanya kudzidzwa NAD + precursors. Inotorwa nyore nyore uye inoshandiswa nemuviri. Zvidzidzo zvakawanda zvakaratidza kuti kuwedzera NR kunogona kuwedzera NAD + mazinga, ayo anogona kuunza mabhenefiti kune metabolic, moyo uye tsinga masisitimu.
Izwi rokuti "anti-aging" rinowana rap yakaipa. Zvinoita sekunge tiri kuedza kumisa chimwe chinhu chave kutoitika, kana kuti hatikwanise kumbundira zvikamu zvedu izvo zvatinofanira kuda. Asi chokwadi ndechekuti shanduko yemetabolism inoitika pasi peganda tisati taona mhedzisiro yekuchembera. Kusarudza kutaura nezveutano hwedu kubva mukati zvichienda kungava izvo chaizvo zvatinoda kuti tivandudze nzira yatinokwegura.
Muchokwadi, chimwe chezviratidzo zvekuchembera inzira inozivikanwa se "mitochondrial dysfunction," izwi rinoreva kurasikirwa kwakawanda kwesimba uye kugona kwemasero edu nekufamba kwenguva. Ichi chingava chimwe chezvikonzero nei tichichembera. Kana mitochondria iri pamwoyo wekuchembera kwedu, zvakakodzera kuti tiongorore nzira dzese dzekuti dzirambe dzichishanda kwenguva yakareba sezvinobvira.
Dzidza nezve mitochondria.
Mukati mesero rose mune aya madiki, ane chimiro chisinganzwisisike anonzi mitochondria—“simba resero.” Idzi nhengo diki dzinoita basa rekuburitsa 90% yesimba rinodiwa nemiviri yedu. Mitochondria ndicho chikonzero tiripo nhasi semhuka dzakaoma kwete mabhakitiriya.
Hatigari tichiziva kuti mitochondria yakakosha sei kuhutano hwedu. Nzira yakakosha yekuchengetedza mitochondria yako ine hutano imorekuru rinonzi NAD+ (nicotinamide adenine dinucleotide). Masero edu anongogadzira NAD + uye isu tinoramba tichiishandisa zuva rese.
Isu tinoziva zvakare kuti kupihwa kwedu kweNAD + kunodzikira sezvatinokura. Vatsvagiri pavakangoona kuti NAD + inogona kubata kiyi yekuchengetedza masero edu ane hutano, vakatsvanzvadzira kutsvaga nzira yekuita zvakanyanya.
Vatsvagiri vanotoziva kuti mavhitamini maviri anotanga maitiro emakemikari ekuwedzera NAD +: niacin uye niacinamide. Izvi zvakawanikwa muma1930s kurapa pellagra, inogona kuuraya vhitamini B3 kushomeka.
Niacin yaizoenderera mberi kuve mushonga weiyo cholesterol yakakwira muma1950s. Zvisinei, zvakaonekwa kuti kunwa madosi makuru e niacin dzimwe nguva kunogona kukonzera kusvotesa kweganda kunoshatirisa uye kusingataridzike.
Niacinamide haikonzere kuyerera kweganda uye inokwanisa kupa akawanda mabhenefiti akafanana, asi inotadzisa kuvhurwa kweakakosha masero ekugadzirisa-anosimudzira mapuroteni anonzi sirtuins. Hapana niacinamide kana niacin yakashanda sezvaitarisirwa nevaongorori.
Kunyangwe aya mavhitamini maviri ari NAD + precursors, haisi mhinduro yakanaka. Nekuda kweiyo yakaipa mhedzisiro ye niacin uye hukama hwekuita kwe nicotinamide, vaongorori havasati vane yakakwana yakakwana vhitamini yekuwedzera kuwedzera NAD+ mazinga.
Kuwanikwa kwe nicotinamide riboside.
Imwe mhando yevhitamini B3 inonzi nicotinamide riboside yakawanikwa mumbiriso muma1940s. Asi hazvina kusvika kutanga kwe2000s apo vesainzi vakatanga kuona kugona kwevhitamini iyi yechitatu, B3, kwete kungowedzera NAD + asiwo kuvandudza hutano hwevanhu. Muna 2004, chikwata cheDartmouth College chekutsvagisa chakawana kuti nicotinamide riboside, senge vhitamini B3 mukoma, inotungamira kuNAD +.
Chikwata chekutsvagisa chinotungamirwa naDr. Charles Brenner chakawana kuti nicotinamide riboside yakawedzera NAD + mumakonzo, uye mbeva dzakasangana nehuwandu hwehutano hunobatsira semhedzisiro.
Mbeva dzakaratidza zvese kubva pakuvandudzwa kweshuga yeropa uye cholesterol mazinga kusvika kudzikisira kukuvara kwetsinga uye kuramba kurema. Dr. Charles Brenner akawana zvigumisiro izvi zvichikurudzira zvokuti akatora danho rinotevera kuti anzwisise zvinoreva nicotinamide riboside kune hutano hwevanhu.
Muna 2014, Dr. Brenner vakave munhu wekutanga kutora nicotinamide riboside sekuwedzera. Migumisiro yacho inokurudzira zvakafanana. Iyi fomu isingazivikanwe yevhitamini B3 yakawedzera zvakanyanya mazinga ake eNAD+ zvakachengeteka, nekukurumidza, uye pasina chero yakaipa mhedzisiro.
Nicotinamide riboside inoshandisa yakasarudzika nzira kugadzira NAD + iyo isina imwe vhitamini B3 inoshandisa.
Nicotinamide riboside inogona zvakare kumisa sero kugadzirisa-kusimudzira mapuroteni sirtuins. Sezvatinokura, aya ma sirtuin anoshanda nguva yakawandisa kubatsira maseru kuti arambe akasimba.
Kugara uine hutano sezera rako hazvimbofi zvakapusa sevhitamini imwe, kunyangwe paine inovimbisa senicotinamide riboside. Kune zvinopfuura zana zvidzidzo zvinoongorora nicotinamide riboside, mazhinji ayo anoratidza kuti yakawedzera NAD + mazinga ane hukama nehutano hwemetabolism uye mhasuru mumakonzo. Tsvagiridzo yekuwedzera irikuenderera mberi kuti unzwisise basa reNAD+ mukutsigira mamwe matambudziko ane hukama nezera, anosanganisira kudzikira kwekushanda kwechiropa, kurema, mazinga einsulin uye kushanda kwehuropi mumakonzo.
Chii chinonzi NAD?
NAD+ is coenzyme I, inova coenzyme inotamisa maproton (chaizvo, mahydrogen ions) uye inotora chikamu muzviitiko zvakawanda zvemuviri senge cellular material metabolism, simba rekugadzira, uye kugadzirisa DNA. NAD + chikafu chinodiwa pakushanda kweSirtuin protein, inonzi "hupenyu hurefu chinhu" nemasayendisiti. Kunyanya, inogona kuchengetedza hurefu hwematelomere akakosha, inonoke kuchembera uye kuwedzera hupenyu.
NAD + inogonawo kukurudzira kugadzirisa majini uye kunonoka kuchembera kwesero. NAD + inosimudzira kudzoreredzwa kwesero uye inoramba immune system zvirwere. NAD + inovandudza kugadzikana kwechromosome uye inoderedza njodzi yegomarara.
Iwo ma enzymes 'shamwari dzepamoyo, anobatsira kupisa "cellular machine" iyo inogadzira simba rinodiwa kune ese makuru basa mumuviri wako padanho remaserura.
Nei NAD+ yakakosha?
Nekuda kwebasa rayo rakakosha mukugadzirwa kwesimba remagetsi, kushomeka kweNAD + mumuviri wako kunoita kuti mabasa mazhinji emuviri ashaye basa. Pasina NAD, mapapu ako haakwanise kutora mweya weokisijeni, moyo wako haugone kupomba ropa, uye uropi hwako husina kupfuta.
NAD+ inobatsirawo kusimudzira kugadzirisa kweDNA uye kudzora kuita kwesero nekushanda nemasirtuins uye poly(ADP-ribose) polymerases (PARPs), ayo akakosha mukugadzirisa mhinduro dzemaserura kukutuka senge kudyisa, kunwa doro, kukanganisa kurara, uye kugara pasi maitiro. Enzymes.
NAD + uye kuchembera
Tsvagiridzo yakaitwa muna 2012 nechikwata cheDhipatimendi rePharmacology paYunivhesiti yeNew South Wales yakaratidza kuti NAD metabolism inodyidzana nezera. Chidzidzo ichi chinoratidza kuti mazinga eNAD + munyama yeganda remunhu anoderera kusvika pamakumi mashanu muzana pakati pemakore makumi mana nemakumi matanhatu, uye kuti kuderera kweNAD + kunogona kuita basa rakakosha mukuchembera.
"Kubatana kwakasimba kwakashata kwakaonekwa pakati peNAD + mazinga uye zera muvarume nevakadzi," vaongorori vakadaro mubepa.
Pamusoro pezvo, NAD inobatanidzwa mukufema kweserura, kunyanya mumitochondria, uye inobatsira kuhutano hwemitochondrial. Pane kufarira kwakasimba kwesainzi mukubatanidzwa kweNAD mumitochondrial dysfunction, chimwe chezviratidzo zvekuchembera.
Mumakore achangopfuura, tsvakiridzo yakanangana nekunzwisisa basa reNAD mukugadzirisa izvi zvine chekuita nezera kuderera kwekushanda.
Nicotinamide Ribose Chloride inowedzera NAD + mazinga.
NR inofanotungamira kuNAD, zvinoreva kuti ndiyo "chivakwa chekuvaka" kubva panogadzirwa NAD + mamorekuru. Yakawanikwa muna 2004 sevhitamini inotangira kuNAD +, ichiiita imwe yezvinobuda mukutsvaga kweNAD +.
NR ivhitamini inongoitika uye chimiro chitsva chevhitamini B3, asi kushandiswa kwayo sekuwedzera kwakakanganiswa ne "utano hwekuchembera". Inoshanda zvakanyanya pakuwedzera NAD, zvichiita kuti ive imwe yeanonyanya kupindira mune hutano hwekuchembera mhinduro.
NR inogona kunyatso kuwedzera NAD + mazinga. Muedzo wekiriniki wakabudiswa muScientific Reports wakaratidza kuti yakawedzera NAD+ kusvika ku50% mushure memavhiki maviri ekuitora.
Kunyangwe NR yekuwedzera yakaratidzirwa nekiriniki kuti iwedzere NAD + mazinga, NAD + yekuwedzera sechinhu chakamira chega haisi iyo inoshanda.
NAD+ imorekuru rakakura kwazvo uye haigone kupinda maseru zvakananga. Pane kudaro, muviri wako unofanirwa kuuputsa kuita zvidimbu zvidiki usati wayambuka membrane yesero. Izvi zvikamu zvakabatanidzwa zvakare mukati mebhatiri.
Nicotinamide riboside (NR) uye nicotinamide riboside chloride (NRC) ese ari maviri emhando yevhitamini B3, inozivikanwawo se niacin. Vitamin B3 chikafu chakakosha chinoita basa rakakosha mumhando dzakasiyana dzemabasa emuviri, kusanganisira kugadzirwa kwesimba, kugadzirisa DNA, uye sero metabolism. Ose ari maviri NR neNRC ndiwo anotangira nicotinamide adenine dinucleotide (NAD +), coenzyme inobatanidzwa mumhando dzakasiyana dzezvipenyu, sekudzora kugadzirwa kwesimba remagetsi uye kutsigira kugadzirisa kweDNA.
Nicotinamide riboside (NR) imhando yevhitamini B3 iyo yakawana kutariswa kune yayo inogona kudzivirira kuchembera uye simba-inosimudzira zvivakwa. Icho chigadziro chinoitika chinowanikwa muhuwandu hwekutsvaga mune zvimwe zvekudya, asi inowanikwawo sechikafu chekuwedzera. NR inozivikanwa nekugona kwayo kuwedzera mazinga eNAD + mumuviri, ayo anogona kutsigira mitochondrial basa, kuwedzera kugadzirwa kwesimba remaserura, uye inogona kupa dziviriro kubva mukuderera kwezera.
Nicotinamide riboside chloride (NRC), kune rumwe rutivi, imhando yemunyu yeNR uye inowanzoshandiswa mukudya kwekuwedzera. Kuwedzera chloride kuNR kunoburitsa NRC, iyo inotendwa kuti inowedzera kugadzikana kwekomboni uye bioavailability. Izvi zvinoreva kuti NRC inogona kunge iine kunyura uye kushandiswa zviri nani mumuviri kupfuura NR chete uye inogona kunge iine chirevo chakanyanya paNAD + mazinga uye cellular basa.
Imwe yemisiyano mikuru pakati peNR neNRC ndiyo chimiro chavo chemakemikari. NR ndiyo yekutanga fomu yekomboni iyi, nepo NRC iri yakagadziridzwa vhezheni ine yakawedzera chloride. Kugadziridzwa uku kunoitirwa kuwedzera kunyungudika kwekomboni uye bioavailability, zvichiita kuti zvive nyore kuti muviri utore nekuishandisa.
Nezvehutano hwavo hunogona kubatsira, NR neNRC inofungidzirwa kuva nemigumisiro yakafanana nekuda kwekukwanisa kwavo kuwedzeraNAD+mazinga. Izvi zvinogona kusanganisira kuvandudzwa kwemitochondrial basa, kuwedzeredzwa simba metabolism, uye inogona kutsigira hutano hwesero. Nekudaro, kushandisa NRC mukuwedzera kunogona kuunza iyo yakawedzerwa mukana wekutora zvirinani uye kushandiswa, izvo zvinogona kuguma nemabhenefiti akanyanya kutaurwa zvichienzaniswa nekushandisa NR chete.
1. Kuvandudza kugadzirwa kwesimba remagetsi
Imwe yeanonyanya kukosha mabhenefiti enicotinamide riboside chloride ibasa rayo mukusimudzira kugadzirwa kwesimba remagetsi. NR ndiyo inotangira nicotinamide adenine dinucleotide (NAD+), coenzyme inoita basa mukugadzirwa kweadenosine triphosphate (ATP), iyo sero yekutanga simba remari. basa rinokosha. Sezvo isu tichikura, mazinga eNAD + anodzikira, zvichikonzera kudzikiswa kwekugadzirwa kwesimba remagetsi. Nekuwedzera neNR, zvinotendwa kuti NAD + mazinga anogona kuzadzikiswa, nekudaro achitsigira yakakwana cellular simba metabolism.
2. Mitochondrial basa uye hupenyu
Mitochondria ndiwo masimba emusero, ane basa rekugadzira simba uye kudzora maserura maitiro. Tsvagiridzo inoratidza kuti Nicotinamide Riboside Chloride inogona kutsigira mitochondrial basa nekusimudzira biogenesis ye mitochondria nyowani nekuwedzera kugona kwavo. Izvi zvine zvazvinoreva kune hupenyu hwese uye kuchembera kune hutano, sezvo mitochondria inoshanda zvakanaka yakakosha pakuchengetedza hutano hweserura uye kusimba.
3. Metabolic hutano uye uremu manejimendi
NAD + ndeye coenzyme, kana kuti mamorekuru ekuwedzera, anobatanidzwa mukuita kwakawanda kwebiology. Ongororo ichangoburwa yakawana kuti nicotinamide ribose yekuwedzera inogona kunyatso kusimudzira NAD + metabolism mune vane hutano hwepakati uye vakuru vakuru. Kwete chete kuti NR yekuwedzera yakatenderwa zvakanaka nevatori vechikamu, inogona kunge yakabatsira kuderedza BP uye arterial kuoma. Kushaikwa kweNAD + ndiyo yakajairika chikonzero chekuchembera uye zvirwere zvakawanda, uye tsvagiridzo inoratidza kuti kudzoreredza NAD + mazinga ane hukuru hwekurapa uye hutano.
Nekuwedzera NAD + mazinga, nicotinamide ribose inobatsira metabolic regulation, simba rekuchengetedza, DNA synthesis, uye mamwe mabasa emuviri.
Pamusoro pezvo, zvidzidzo zvakaratidza kuti NR yekuwedzera inogona kuvandudza insulin senitivity, kuderedza kuzvimba, uye kuwedzera metabolic kushanduka. Izvi zvinogona kunyanya kubatsira kune vanhu vanoda kudzora uremu hwavo uye kutsigira hutano hwese metabolic.
4. Basa rekuziva uye hutano hwehuropi
Seyakatangira kuNAD +, nicotinamide ribose inodzivirira masero ehuropi kubva mukushushikana kweiyo oxidative, izvo zvinogona kutungamira kuzvirwere zvehuropi zvine hukama. Mukati memasero ehuropi, NAD + inobatsira kudzora kugadzirwa kwePGC-1-alpha, puroteni inoita seinobatsira kudzivirira masero kubva mukushushikana kweiyo oxidative uye kukanganisa mitochondrial basa.
Vatsvagiri vakaona kuti mumakonzo, kupera kweNAD + kunotora basa rakakosha muuroinflammation, kukuvadzwa kweDNA, uye kuderera kweuronal muchirwere cheAlzheimer. Zvakare muchidzidzo chetest-tube, nicotinamide riboside yakawedzera NAD+ mazinga uye yakavandudza zvakanyanya mitochondrial basa mumaseru evarwere veParkinson's disease.
Tsvagiridzo ichiri kusimukira inonongedzawo kune zvingangoita zvekuziva mabhenefiti e nicotinamide riboside chloride. NAD+ inobatanidzwa mune akasiyana maitiro ane chekuita nehutano hwehuropi, kusanganisira neuronal kusaina, kugadzirisa kweDNA, uye kubviswa kwemapuroteni akakuvadzwa. Nekutsigira mazinga eNAD +, NR inogona kubatsira kuchengetedza basa rekuziva uye kudzivirira kuderera kwekuziva kwakabatana nezera.
5. Kutamba Kwemitambo uye Kudzorera
Chidzidzo che2019 chakaburitswa muEuropean Journal yeNutrient Impurities chakawana kuti kushandisa nicotinamide ribose yekuwedzera kwakavandudza hunyanzvi hwemuviri uye kuderedza oxidative kusagadzikana muvakuru vakuru.
Vatsvakurudzi vakagumisa kuti NR yekuwedzera yaibatsira kune NAD + vanhu vasina kukwana, vachitsanangura kuti sei yainyanya kushanda kune vakuru vakuru kupfuura vadiki.
Vamhanyi uye vanofarira kusimba vanogona kufarira kuziva kuti nicotinamide riboside chloride inogona kukanganisa kuita kwemitambo uye kupora. NAD + inobata basa rakakosha mukudzora maserura maitiro anosanganisirwa mukugadzirwa kwesimba uye kushanda kwemhasuru. Nekutsigira NAD + mazinga, NR inogona kuwedzera kutsungirira, kuvandudza tsandanyama kupora, uye kuwedzera kuita kwese kwemitambo.
Hunhu uye Kuchena
Paunenge uchitenga nicotinamide riboside chloride poda, mhando uye kuchena kunofanira kunge kuri pamberi pako. Tarisa zvigadzirwa zvakagadzirwa nemakambani ane mukurumbira uye wechitatu-bato akaedzwa kuchena uye potency. Sezvineiwo, zvigadzirwa zvinofanirwa kunge zvisina zvinosvibisa uye mafirita kuona kuti uri kuwana yemhando yepamusoro yekuwedzera iyo inopa mabhenefiti akatarisirwa.
Dosage uye kushandiswa
Usati waisa nicotinamide riboside chloride poda mune yako yemazuva ese maitiro, zvakakosha kuti unzwisise chaiyo dosi uye mashandisiro ekushandisa. Zvakakosha kutanga nedosi yakaderera uye zvishoma nezvishoma kuwedzera sezvinodiwa, sezvo mazinga epamusoro haafaniri kuenzana nemigumisiro iri nani uye inogona kukonzera migumisiro yakaipa. Pamusoro pezvo, ndapota funga kubvunzana nenyanzvi yezvehutano kuti uone dosi iyo yakanakira yako chaiyo hutano zvinangwa uye zvaunoda.
Zvinogona kubatsira uye kufunga
Nicotinamide Riboside Chloride Powder inowanzo pihwa mabhenefiti ayo, kusanganisira kutsigira mazinga esimba, mitochondrial basa, uye hutano hwesero. Tsvagiridzo inoratidza kuti inogona zvakare kukanganisa kuchembera uye zvirwere zvine chekuita nezera.
Chengetedzo nedziviriro
Sezvakaita chero chekuwedzera, zvakakosha kuisa pamberi pekuchengetedza uye kunzwisisa zvingangove zvekudzivirira. Kunyangwe nicotinamide riboside chloride ichiwanzotenderwa zvakanaka, vamwe vanhu vanogona kuona zvakapfava mhedzisiro, sekusagadzikana kwemudumbu. Pamusoro pezvo, kana uine chero mamiriro ehutano ari pasi kana uri kutora mishonga, iva nechokwadi chekubvunza nyanzvi yezvehutano usati washandisa ichi chekuwedzera kuti uone kuti chakachengeteka uye chakakodzera mamiriro ako pachako.
Sarudza mutengesi ane mbiri
Kana uchitenga Nicotinamide Riboside Chloride Powder, zvakakosha kuti usarudze mutengesi ane mukurumbira anoisa pamberi pemhando, pachena, uye kugutsikana kwevatengi. Tarisa makambani anopa ruzivo nezve maitiro avo ekugadzira, kutsvaga, uye yechitatu-bato kuyedzwa. Pamusoro pezvo, funga kuverenga wongororo yevatengi uye kutsvaga kurudziro kubva kune akavimbika masosi kuti uve nechokwadi chekuti uri kutenga kubva kune akavimbika uye akavimbika mutengesi.
Suzhou Myland Pharm & Nutrition Inc. yave ichiita bhizinesi rekuwedzera chikafu kubva muna 1992. Ndiyo kambani yekutanga muChina kugadzira nekutengesa mhodzi dzemazambiringa.
Iine makore makumi matatu echiitiko uye ichitungamirwa nehunyanzvi hwepamusoro uye yakagadziridzwa zvakanyanya R&D zano, kambani yakagadzira mhando yezvigadzirwa zvemakwikwi uye ikava yekuvandudza hupenyu hwesainzi yekuwedzera, yetsika synthesis uye kambani yekugadzira masevhisi.
Pamusoro pezvo, Suzhou Myland Pharm & Nutrition Inc. zvakare iri FDA-yakanyoreswa mugadziri. Zviwanikwa zvekambani zveR&D, zvivakwa zvekugadzira, uye zviridzwa zvekuongorora ndezvazvino uye zvinoshanda uye zvinogona kugadzira makemikari kubva kumamirigiramu kusvika kumatani muchiyero, uye zvinoenderana neISO 9001 zviyero uye magadzirirwo ekugadzira GMP.
Mubvunzo: Chii chinonzi nicotinamide riboside chloride powder?
A: Nicotinamide Riboside Chloride Powder imhando yevhitamini B3 yakadzidzwa kuitira kugona kwayo kutsigira kugadzirwa kwesimba remagetsi uye metabolism. Inowanzoshandiswa sechikafu chekuwedzera kusimudzira hutano hwese uye hutano.
Mubvunzo: Ndezvipi zvingave zvinobatsira zve nicotinamide riboside chloride powder?
A: Zvimwe zvingangobatsira zveNicotinamide Riboside Chloride Powder zvinosanganisira kutsigira mitochondrial basa, kukurudzira kuchembera kune hutano, uye kuwedzera kutsungirira uye kuita kwemuviri. Inogonawo kubatsira kutsigira basa rekuziva uye hutano hwesero.
Mubvunzo: Ndingatenga kupi nicotinamide riboside chloride powder?
A: Nicotinamide Riboside Chloride poda inowanikwa kubva kune vakasiyana vatengesi uye zvitoro zvepamhepo. Paunenge uchitenga ichi chekuwedzera, zvakakosha kuti usarudze chitubu chine mukurumbira kuti uve nechokwadi chemhando uye chengetedzo.
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Nguva yekutumira: Aug-14-2024