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Kuongorora Hunhu, Mabasa, uye Mashandisirwo e7,8-Dihydroxyflavone

Mumakore achangopfuura, nharaunda yesainzi yakawedzera kutarisisa pane zvingangoita hutano mabhenefiti ezvakasiyana masikirwo emakemikari, kunyanya flavonoids. Pakati peizvi, 7,8-dihydroxyflavone (7,8-DHF) yakabuda semusanganiswa wekufarira nekuda kwemaitiro ayo akasiyana uye mabasa anovimbisa. Ichi chinyorwa chinotarisa mukati mezvivakwa, mabasa, uye zvingangoita mashandisiro e7,8-dihydroxyflavone, ichijekesa kukosha kwayo muhutano uye hutano.

Hunhu hwe7,8-Dihydroxyflavone

7,8-Dihydroxyflavoneis flavonoid, kirasi yemapolyphenolic makomisheni akaparadzirwa zvakanyanya muumambo hwechirimwa. Inonyanya kuwanikwa mumichero yakasiyana-siyana, miriwo, uye miriwo, inobatsira kune mavara ane simba uye hutano hunobatsira hunobatanidza nezvokudya izvi. Iyo kemikari chimiro che7,8-DHF ine flavone musana nemapoka ehydroxyl pa7 uye 8 zvinzvimbo, izvo zvakakosha pakuita kwayo biological.

Chimwe chezvinhu zvinonyanya kukosha zve7,8-DHF kunyungudika kwayo. Iyo yero crystalline poda inonyungudika mune organic solvents senge dimethyl sulfoxide (DMSO) uye ethanol, asi ine mashoma solubility mumvura. Ichi chivakwa chakakosha pakugadzirwa kwayo mune akasiyana maapplication, kusanganisira ezvekudya uye zvigadzirwa zvemishonga.

Mushonga wacho unozivikanwa nekugadzikana kwayo pasi pemamiriro ezvinhu, zvichiita kuti ive yakakodzera kune zvakasiyana-siyana. Zvisinei, kufanana nemafuta akawanda eflavonoid, inogona kuva nehanya nechiedza uye kupisa, izvo zvingakanganisa kushanda kwayo. Naizvozvo, kuchengetedza kwakaringana uye kubata kwakakosha kuchengetedza zvinhu zvayo zvinobatsira.

Mabasa e7,8-Dihydroxyflavone

Izvo zvipenyu zvinoshanda zve7,8-dihydroxyflavone yanga iri nyaya yekutsvagisa kwakawanda, ichiratidza huwandu hwehumwe hutano hunobatsira. Rimwe remabasa akanyanya kukosha anonzi ane flavonoid iyi ndeye neuroprotective effect. Zvidzidzo zvakaratidza kuti 7,8-DHF inogona kukurudzira kupona kwemaneuroni uye kuwedzera kugona kwekuziva. Izvi zvinonyanya kukosha mumamiriro ezvirwere zveurourodegenerative senge Alzheimer's uye Parkinson's, uko oxidative kusagadzikana uye kuzvimba kunoita basa rakakosha mukufambira mberi kwechirwere.

7,8-DHF inotendwa kuti inoshandisa mhedzisiro yayo neuroprotective kuburikidza nemaitiro akati wandei. Yakaratidzwa kuti iite kuti tropomyosin receptor kinase B (TrkB) isaina nzira, iyo yakakosha pakupona neuronal uye kusiyanisa. Nekushandisa nzira iyi, 7,8-DHF inogona kuwedzera neurogenesis uye synaptic plasticity, zvichiita kuti kuve nekuvandudzwa kwekuziva uye ndangariro.

Mukuwedzera kune yayo neuroprotective properties, 7,8-DHF inoratidza anti-inflammatory uye antioxidant zviitiko. Izvi zvinhu zvakakosha pakurwisa oxidative kusagadzikana, iyo yakabatana kune dzakasiyana siyana zvirwere zvisingaperi, kusanganisira chirwere chemoyo, chirwere cheshuga, uye cancer. Nekutsvaira mahara radicals uye kuderedza kuzvimba, 7,8-DHF inogona kubatsira kudzikisira njodzi yemamiriro aya.

Uyezve, 7,8-DHF yakaongororwa nezve mukana wayo muhutano hwemetabolism. Zvidzidzo zvekutanga zvinoratidza kuti inogona kuvandudza insulin senitivity uye glucose metabolism, zvichiita kuti ive mumiriri wekugadzirisa mamiriro akadai serudzi rwechipiri chirwere cheshuga. Iko kugona kwekomboni kugadzirisa nzira dzemetabolism kunogona kuve nemhedzisiro yakakosha pakuremerwa uye hutano hwese metabolic.

Zvikumbiro zve7,8-Dihydroxyflavone

Zvikumbiro zve7,8-Dihydroxyflavone

Tichifunga nezvemabasa ayo akasiyana, 7,8-dihydroxyflavone yakawana kutarisisa muzvikamu zvakasiyana, kusanganisira zvinovaka muviri, mishonga yemishonga, uye zvizorwa. Zvishandiso zvaro zvingangove zvakakura, uye tsvakiridzo inoenderera mberi ichiburitsa mitsva mitsva.

1. Zvokudya Zvokudya: Kushandiswa kunonyanya kushandiswa kwe7,8-DHF kuri muzvokudya zvinovaka muviri zvine chinangwa chekusimudzira kushanda kwepfungwa uye utano hwose. Semusanganiswa wechisikigo une neuroprotective properties, inowanzotengeswa se nootropic, inokwezva kune vanhu vari kutsvaga kuvandudza ndangariro, kutarisa, uye kujeka kwepfungwa. Zvekuwedzera zvine 7,8-DHF zvinowanzo kuwanikwa muupfu kana capsule fomu, zvichiita kuti zvive nyore kuisirwa mumaitiro ezuva nezuva.

2. Pharmaceutical Development: Indasitiri yemishonga iri kuongorora zvingangoitika zve7,8-DHF semushonga wekurapa wezvirwere zvinokonzerwa neurodegenerative. Miedzo yemakiriniki iri kuenderera mberi yekuongorora kushanda kwayo uye kuchengetedzeka mukurapa mamiriro akaita sechirwere cheAlzheimer. Kana ikabudirira, 7,8-DHF inogona kuvhura nzira yesarudzo itsva dzekurapa dzinonangana nemaitiro ari pasi pezvirwere izvi.

3. Zvigadzirwa zveCosmetic: The antioxidant uye anti-inflammatory properties ye7,8-DHF inoita kuti ive chinhu chinokwezva mukugadzirwa kwezvizoro. Iri kuiswa muzvigadzirwa zve skincare zvine chinangwa chekudzikisa zviratidzo zvekuchembera, kudzivirira kubva kune zvinonetsa kwezvakatipoteredza, uye kusimudzira hutano hweganda. Kugona kwayo kukwidziridza basa remaserura kunogona kubatsira mukuvandudza ganda uye kutaridzika.

4. Functional Foods: Sezvo vatengi vanova nehanya neutano, kune chido chiri kukura muzvokudya zvinoshanda zvinopa humwe hutano hwehutano. 7,8-DHF inogona kuisirwa muzvigadzirwa zvakasiyana-siyana zvekudya, sezvinwiwa, masvutugadzike, uye ma supplements, kuwedzera chimiro chavo chekudya. Aya maitiro anowirirana nekuwedzera kuri kuda kwezvinhu zvakasikwa zvinotsigira hutano hwese.

Mhedziso

7,8-Dihydroxyflavone flavonoid inoshamisa ine huwandu hwemaitiro uye mabasa anoita kuti ive yakakosha mukomboni muhutano uye hutano. Yayo neuroprotective, anti-kuzvimba, uye antioxidant zvimiro zvinoimisa senge inogona kurapa mumiririri kune akasiyana hutano mamiriro, kunyanya neurodegenerative zvirwere uye metabolic kusagadzikana.

Sezvo tsvagiridzo ichienderera mberi kuburitsa huwandu hwakazara hwemabhenefiti ane hukama ne7,8-DHF, mashandisiro ayo mune zvekudya zvinowedzera, mishonga yemishonga, zvekuzora, uye zvinoshanda zvekudya zvinogona kuwedzera. Nekudaro, zvakakosha kuti vatengi vauye kune zvigadzirwa izvi nekuchenjerera, sezvo kushanda uye kuchengetedzeka kwe7,8-DHF kunogona kusiyana zvichienderana nekuumbwa uye hutano hwemunhu.

Muchidimbu, 7,8-dihydroxyflavone inomiririra nzvimbo inovimbisa yekudzidza mukati menzvimbo yemasikirwo emakomponi, ichipa tariro yekuvandudzwa kwehutano uye hupenyu hunovandudzwa. Sezvo isu tichiramba tichiongorora kugona kweiyi flavonoid, zvakakosha kutsigira kuenderera mberi kwekutsvaga nekusimudzira kuti tinzwisise zvizere kugona kwayo uye mashandisiro mumaitiro ehutano emazuva ano.

 

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Nguva yekutumira: Nov-29-2024