Mukutsvaga kurarama kwenguva refu uye kudzivirira kukwegura, vanhu vanogara vachitsvaga zvinhu zvitsva uye zvekudya zvinovaka muviri. Calcium alpha-ketoglutarate (CaAKG) chinhu chiri kukwezva mukurumbira munharaunda yehutano nekugara zvakanaka. Chinhu ichi chakaongororwa nekuda kwekugona kwacho kuwedzera hupenyu uye kurwisa mhedzisiro yekukwegura, zvichiita kuti chiwedzere kufadza munyika yezvekudya zvinovaka muviri. Saka, chii chaizvo chinonzi calcium alpha-ketoglutarate? Inoshanda sei?
Calcium Alpha ketoglutarate (AKG) chinhu chiri pakati nepakati che tricarboxylic acid cycle uye chinobatanidzwa mukugadzira amino acids, mavhitamini, uye organic acids uye simba metabolism. Inogona kushandiswa sekuwedzera kwekudya uye ine mikana yakawanda yekushandiswa. Kuwedzera kumabasa ayo ehupenyu mumuviri wemunhu, calcium alpha-ketoglutarate inoshandiswawo zvakanyanya mumunda wemishonga uye yave chikamu chakakosha chezvigadzirwa zvakawanda zvehutano uye mhinduro dzekurapa.
Mashandiro anoita calcium alpha-ketoglutarate
Chekutanga,calcium alpha-ketoglutarateinoita basa rakakosha mukushandiswa kwesimba. Sechigadzirwa chepakati che tricarboxylic acid cycle (TCA cycle), calcium α-ketoglutarate inobata basa rekugadzira simba mukati memasero. Kuburikidza neTCA cycle, zvinovaka muviri zvakaita semakabhohaidhiretsi, mafuta, uye mapuroteni zvinosanganiswa uye zvinoora kuti zvigadzire ATP (adenosine triphosphate) kuti ipe simba kumasero. Sechikamu chakakosha cheTCA cycle, calcium α-ketoglutarate inogona kukurudzira kushandiswa kwesimba remasero, kuwedzera simba remuviri, kubatsira kuwedzera simba remuviri nekutsungirira, uye kuvandudza kuneta kwemuviri.
Chechipiri, calcium α-ketoglutarate inoita basa rakakosha mukushandiswa kwemaamino acid. MaAmino acid ndiwo mayuniti ekutanga emapuroteni, uye calcium α-ketoglutarate inobatanidzwa mukushandurwa uye kushandiswa kwemaamino acid. Mukushandura maamino acid kuita mamwe ma metabolites, calcium α-ketoglutarate inochinjana nemaamino acids kugadzira maamino acid matsva kana α-keto acids, nokudaro ichidzora kuenzana uye kushandiswa kwemaamino acids. Pamusoro pezvo, calcium α-ketoglutarate inogona zvakare kushanda senzvimbo yekuoxidation yemaamino acids, kutora chikamu mukushandiswa kwemaamino acids, uye kugadzira simba necarbon dioxide. Naizvozvo, calcium α-ketoglutarate inokosha zvikuru mukuchengetedza homeostasis yemaamino acids uye kushandiswa kwemapuroteni mumuviri.
Pamusoro pezvo, calcium alpha-ketoglutarate inoshanda seantioxidant inobvisa ma free radicals uye inodzivirira masero kubva mukukuvadzwa kwe oxidative. Panguva imwe chete, calcium α-ketoglutarate inogonawo kudzora mashandiro e immune system, kukurudzira kushanda uye kuwanda kwemasero e immune system, uye kuwedzera kudzivirira kwemuviri kuzvirwere nehutachiona. Nokudaro, calcium α-ketoglutarate inokosha zvikuru mukuchengetedza kuenzana kwe immune system yemuviri uye kudzivirira zvirwere.
Tsvakurudzo pamusoro pemigumisiro yekukwegura
Kukwegura kunokanganisa isu tese uye chinhu chinokonzera zvirwere zvakawanda, uye zvichienderana nehuwandu hwevanhu vari muindasitiri yeMedicare, mukana wekukura nechirwere unowedzera nekukura. Kuti kuderedze kukwegura uye kuderedza njodzi yechirwere zvinobudirira, tsvakurudzo yakawana chinhu chakachengeteka uye chinoshanda mumuviri chinogona kukanganisa kukwegura - calcium alpha-ketoglutarate.
Calcium alpha-ketoglutarate chinhu chakakosha mumuviri wedu, chinozivikanwa nebasa resero muKrebs cycle, cycle inokosha pakuoxidation yemafuta acids nemaamino acids, zvichibvumira mitochondria kugadzira ATP (ATP ndiyo sosi yesimba remasero).
Izvi zvinosanganisira kuzara kwe calcium alpha-ketoglutarate process, saka calcium alpha-ketoglutarate inogonawo kushandurwa kuita glutamate uye yozoitwa glutamine, iyo inogona kubatsira kukurudzira kugadzirwa kweprotein ne collagen (collagen iprotein ine fibrous inoumba 1/3 yeprotein yese mumuviri uye inobatsira kutsigira hutano hwemapfupa, ganda uye tsandanyama).
Ponce De Leon Health, Inc., kambani inoongorora hupenyu hurefu yakatarisana nekuderedza kukwegura kwemajini, yakaita ongororo yemakore akawanda yecalcium alpha-ketoglutarate pamakonzo ane makore epakati nepakati uye yakawana kuti hupenyu hwemakonzo ari muboka rekuyedza hwakawedzera ne12%. Chinonyanya kukosha ndechekuti, kushaya simba kwakaderedzwa ne46% uye hupenyu hune hutano hwakawedzera ne41%. Humbowo hunoratidza kuti kuwedzerwa kwealpha-ketoglutarate hakungowedzere hupenyu chete asiwo kuwedzera hupenyu hwehutano zvakanyanya.
Calcium α-ketoglutarate, sechikafu chinowedzera mabasa akawanda, ine mikana yakawanda yekushandiswa muzvigadzirwa zvehutano. Mabasa ayo akasiyana-siyana ehupenyu akadai seantioxidant, anti-aging, immune regulation uye amino acid metabolism anoita kuti ive chishandiso chine simba chekuvandudza hutano hwevanhu. Nekuwedzera kweruzivo rwehutano uye kuwedzera kwekutsvaga kwesainzi, zvinotendwa kuti kushandiswa kweα-ketoglutarate calcium mumunda wezvigadzirwa zvehutano kuchawana kutariswa kwakawanda uye kukura.
Chiziviso: Chinyorwa ichi ndecheruzivo rwese chete uye hachifanirwe kutorwa semazano ekurapa. Mamwe emashoko eblog anobva paInternet uye haasi ehunyanzvi. Iyi webhusaiti ine basa rekugadzirisa, kuronga nekugadzirisa zvinyorwa chete. Chinangwa chekutumira rumwe ruzivo hazvirevi kuti unobvumirana nemaonero ayo kana kusimbisa chokwadi chezviri mukati mayo. Gara uchibvunza nyanzvi yehutano usati washandisa chero mishonga yekuwedzera kana kuita shanduko kuhurongwa hwako hwehutano.
Nguva yekutumira: Nyamavhuvhu-20-2024
