Mukutsvaga hupenyu hurefu uye kurwisa kuchembera, vanhu vanogara vachitsvaga zvinhu zvitsva uye zvekudya zvinowedzera. Calcium alpha-ketoglutarate (CaAKG) chinhu chiri kuwana kutariswa munharaunda yehutano uye hutano. Ichi chikamu chakadzidzwa nekuda kwekugona kuwedzera hupenyu uye kurwisa mhedzisiro yekuchembera, zvichiita kuti ive chinhu chinonakidza chekuwedzera kune chekudya chekuwedzera nyika. Saka, chii chaizvo chinonzi calcium alpha-ketoglutarate? Inoshanda sei?
Calcium Alpha ketoglutarate (AKG) ndeyepakati metabolite ye tricarboxylic acid cycle uye inotora chikamu mukugadzira amino acids, mavitamini, uye organic acids uye simba metabolism. Inogona kushandiswa sechikafu chekuwedzera uye ine tarisiro yakakura yekushandisa. Pamusoro pemabasa ayo ehupenyu mumuviri wemunhu, calcium alpha-ketoglutarate inoshandiswawo zvakanyanya mumunda wemishonga uye yave chinhu chakakosha chezvigadzirwa zvehutano zvakawanda uye mhinduro dzekurapa.
Mashandiro anoita calcium alpha-ketoglutarate
Chekutanga,calcium alpha-ketoglutarateinoita basa rinokosha musimba metabolism. Sechigadzirwa chepakati che tricarboxylic acid cycle (TCA cycle), calcium α-ketoglutarate inotora chikamu mu intracellular simba rekugadzira maitiro. Kuburikidza neTCA kutenderera, zvinovaka muviri zvakaita semakabhohaidhiretsi, mafuta, uye mapuroteni zvakasvibiswa uye zvakasvibiswa kuti zvibudise ATP (adenosine triphosphate) kupa simba kumasero. Seyakakosha yepakati muTCA cycle, calcium α-ketoglutarate inogona kukurudzira cell energy metabolism, kuwedzera simba remuviri, kubatsira kusimbisa simba remuviri uye kutsungirira, nekuvandudza kuneta kwemuviri.
Chechipiri, calcium α-ketoglutarate inoita basa rakakosha muamino acid metabolism. Amino acids ndiwo ekutanga mapuroteni, uye calcium α-ketoglutarate inobatanidzwa mukutendeuka uye metabolism yeamino acids. Muchiito chekushandura maamino acids kuita mamwe metabolites, calcium α-ketoglutarate inotenderera nemaamino acids kuti ibudise amino acids matsva kana α-keto acids, nokudaro kudzora kuenzana nekushandiswa kwemaamino acids. Pamusoro pezvo, calcium α-ketoglutarate inogonawo kushanda senge oxidation substrate yeamino acids, kutora chikamu mune oxidative metabolism yeamino acids, uye kuburitsa simba uye kabhoni dhaibhoni. Naizvozvo, calcium α-ketoglutarate yakakosha zvikuru mukuchengetedza iyo homeostasis yemamino acids uye protein metabolism mumuviri.
Pamusoro pezvo, calcium alpha-ketoglutarate inoshanda se antioxidant inobvisa mahara radicals uye inodzivirira masero kubva mukukuvadzwa kweiyo oxidative. Panguva imwecheteyo, calcium α-ketoglutarate inogonawo kugadzirisa basa rekudzivirira muviri, kukurudzira kushandiswa uye kupararira kwemasero ekudzivirira muviri, uye kuwedzera kudzivirira kwemuviri kuzvirwere uye utachiona. Naizvozvo, calcium α-ketoglutarate yakakosha zvikuru mukuchengetedza immune system yemuviri uye kurwisa zvirwere.
Tsvakurudzo pamusoro pemigumisiro yekukwegura
Kuchembera kunobata isu tese uye ingozi yezvirwere zvakawanda, uye maererano neMedicare indasitiri yedemographics, mukana wekuita chirwere unowedzera nezera. Kuti kuderedze kuchembera uye kudzikisira zvinobudirira njodzi yechirwere, tsvakiridzo yakawana yakachengeteka uye bioactive chinhu chinogona kukanganisa kuchembera - calcium alpha-ketoglutarate.
Calcium alpha-ketoglutarate yakakosha metabolite mumuviri wedu, inozivikanwa nebasa resero muKrebs cycle, kutenderera kwakakosha kune oxidation yemafuta acids uye amino acids, ichibvumira mitochondria kuburitsa ATP (ATP ndiyo simba remasero).
Izvi zvinosanganisira kurodha kwecalcium alpha-ketoglutarate process, saka calcium alpha-ketoglutarate inogona zvakare kushandurwa kuita glutamate uyezve kuita glutamine, iyo inogona kubatsira kukurudzira kuumbwa kweprotein uye collagen (collagen iA fibrous protein inoita 1/3 ye mapuroteni ese ari mumuviri uye anobatsira kutsigira hutano hwemapfupa, ganda uye tsandanyama).
Ponce De Leon Health, Inc., kambani yekutsvagisa hupenyu hurefu yakatarisana nekudzoreredza kuchembera kwemajini, yakaita ongororo yemakore akawanda yakadzorwa yecalcium alpha-ketoglutarate pamakonzo ane makore epakati uye yakaona kuti hupenyu hwembeva muboka rekuyedza rakawedzera ne. 12%. Zvinotonyanya kukosha, Chii zvakare, kusasimba kwakaderedzwa ne46% uye hupenyu hune hutano hwakawedzera ne41%. Humbowo hunoratidza kuti alpha-ketoglutarate yekuwedzera inogona kwete kungowedzera hupenyu asi zvakare kuwedzera hutano hurefu zvakanyanya.
Calcium α-ketoglutarate, seyakawanda inobata chikafu chekuwedzera, ine yakafara tarisiro yekushandisa muzvigadzirwa zvehutano. Mabasa ayo akasiyana-siyana ehupenyu akadai se antioxidant, anti-aging, immune regulation uye amino acid metabolism inoita kuti ive chishandiso chine simba chekuvandudza hutano hwevanhu. Nekuwedzera kwekuziva kwehutano hwehutano uye kudzika kwekutsvakurudza kwesayenzi, zvinotendwa kuti kushandiswa kwe-α-ketoglutarate calcium mumunda wezvigadzirwa zvehutano huchawana kutariswa kwakawanda nekuvandudzwa.
Disclaimer: Ichi chinyorwa ndecheruzivo rwese chete uye hachifanirwe kutorwa sechero zano rekurapa. Imwe yeruzivo rweblog post runobva kuInternet uye haina hunyanzvi. Iyi webhusaiti inongova nebasa rekugadzirisa, kufomatidza uye kugadzirisa zvinyorwa. Chinangwa chekuendesa rumwe ruzivo hachirevi kuti unobvumirana nemaonero ayo kana kusimbisa uchokwadi hwezvirimo. Nguva dzose bvunza nyanzvi yezvehutano usati washandisa chero chekuwedzera kana kuita shanduko kuhutano hwako hwehutano.
Nguva yekutumira: Aug-20-2024
