Inogona Alpha GPC Kuvandudza Kutarisa Kwako? Hezvino Zvaunofanira Kuziva

Kana zvasvika pakuvandudza ndangariro nekudzidza, tsvakiridzo yazvino inoratidza alpha GPC inogona kubatsira zvakanyanya. Izvi zvinodaro nekuti A-GPC inotakura choline kuenda kuuropi, ichikurudzira yakakosha neurotransmitter inosimudzira hutano hwekuziva.

Tsvagiridzo inoratidza alpha GPC ndeimwe yeakanakisa nootropic brain supplements pamusika. Ihwo huropi hunosimudzira molecule iyo yakaratidzwa kuva yakachengeteka uye inobvumirwa zvakanaka nevarwere vakwegura vanotarisa kuvandudza zviratidzo zvekuora mwoyo, pamwe chete nevatambi vechidiki vanotarisa kuvandudza kutsungirira kwavo mumuviri uye simba.
Zvakafanana nehuropi-hunowedzera mhedzisiro yephosphatidylserine, a-GPC inogona kushanda seyakasikwa kurapa kwechirwere cheAlzheimer uye inogona kunonoka kuderera kwekuziva kwakabatana nezera.

Chii chinonzi Alpha GPC?

Alpha GPC kana alpha glycerylphosphorylcholine imorekuru rinoshanda sechitubu checholine. Iyo fatty acid inowanikwa mu soy lecithin nezvimwe zvidyarwa uye inoshandiswa mukuziva hutano hwekuwedzera uye kuvaka simba remhasuru.
Alpha GPC, inozivikanwawo secholine alfoscerate, inokosheswa pakukwanisa kwayo kutakura choline kuenda kuuropi uye kubatsira muviri kuburitsa neurotransmitter acetylcholine, iyo inokonzeresa akawanda ehutano hwecholine. Acetylcholine yakabatana nekudzidza nekuyeuka, uye ndiyo imwe yeanonyanya kukosha neurotransmitters yekumisikidza tsandanyama.
Kusiyana necholine bitartrate, imwe yakakurumbira choline yekuwedzera pamusika, A-GPC inokwanisa kuyambuka iyo yeropa-brain barriers. Ichi ndicho chikonzero chine mhedzisiro inovimbisa pauropi uye nei ichishandiswa kurapa dementia, kusanganisira chirwere cheAlzheimer.

Alpha GPC inobatsira uye inoshandisa

1. Kuvandudza kukanganisa kwendangariro

Alpha GPC inoshandiswa kuvandudza ndangariro, kudzidza uye kugona kufunga. Inoita izvi nekuwedzera acetylcholine muuropi, kemikari inoita basa rinokosha mukuyeuka nekudzidza mabasa. Vatsvakurudzi vakacherechedza kuti alpha GPC ine mukana wekuvandudza zviratidzo zvekuziva zvine chokuita nechirwere cheAlzheimer uye dementia.
Muedzo wakapetwa kaviri-mapofu, wakasarudzika, wakadzorwa neplacebo wakabudiswa muClinical Therapeutics muna 2003 wakaongorora kushanda uye kushivirira kwealpha GPC mukurapa kukanganiswa kwenjere kunokonzerwa nehunyoro kusvika pakati nepakati chirwere cheAlzheimer.
Varwere vakatora 400 mg a-GPC capsules kana placebo capsules katatu zuva nezuva kwemazuva 180. Varwere vose vakaongororwa pakutanga kwekuedza, mushure memazuva makumi mapfumbamwe ekurapwa, uye pakupera kwekuedzwa mazuva 180 gare gare.
Muboka reAlpha GPC, zvose zvakaongororwa parameters, kusanganisira cognitive uye maitiro eAlzheimer's Disease Assessment Scale uye Mini-Mental State Examination, yakaramba ichivandudza mushure me90 uye 180 mazuva ekurapwa, asi muboka re placebo vakaramba vasina kuchinja. kuchinja kana kuipa.
Vatsvakurudzi vakagumisa kuti a-GPC inobatsira uye inobvumirwa zvakanaka mukurapa zviratidzo zvekuora mwoyo uye ine mukana wekurapa kwechirwere cheAlzheimer.

2. Kurudzira kudzidza nekufungisisa

Pane hupfumi hwekutsvagisa hunotsigira mabhenefiti ealpha GPC kune vanhu vane hurema hwekuziva, asi inoshanda sei kune vanhu vasina dementia? Tsvagiridzo inoratidza kuti Alpha GPC inogona zvakare kuvandudza kutarisisa, ndangariro uye kugona kudzidza muvakuru vechidiki vane hutano.
The American Journal of Clinical Nutrition yakaburitsa chidzidzo cheboka chinosanganisira vatori vechikamu vasina dementia uye yakaona kuti kudya kwakakwira choline kwakabatana nekuita kwekuziva kuri nani. Mamiriro ekuziva akaongororwa anosanganisira ndangariro yekutaura, ndangariro yekuona, kudzidza kwekutaura, uye basa rekutonga.
Chidzidzo chakabudiswa mu Journal of the International Society of Sports Nutrition chakawana kuti apo vechidiki vaishandisa alpha GPC supplements, zvaibatsira pane mamwe mabasa emuviri nepfungwa. Avo vakagamuchira 400 mg ye-GPC vakawana 18% nekukurumidza pane serial kubvisa bvunzo pane avo vakagamuchira 200 mg ye caffeine. Pamusoro pezvo, boka rinoshandisa caffeine rakakwira zvakanyanya pane neuroticism zvichienzaniswa neboka realpha GPC.

3. Kuvandudza mitambo yemitambo

Tsvagiridzo inotsigira synergistic zvimiro zvealpha GPC. Nechikonzero ichi, vatambi vari kuwedzera kufarira a-GPC nekuda kwekugona kwayo kuvandudza kutsungirira, kubuda kwesimba, uye kusimba kwemhasuru. Kuwedzera ne-GPC kunozivikanwa kubatsira kuwedzera simba remuviri, kukurudzira kuvakwa kweakaonda mhasuru, uye kupfupisa mushure mekuita basa rekudzoreredza nguva.
Tsvagiridzo inoratidza kuti alpha GPC inowedzera kukura kwevanhu mahormone, ayo anoita basa mukuvandudzwa kwesero, kukura uye kuchengetedza hutano hwevanhu. Kukura kwehomoni inozivikanwa nekugona kwayo kuwedzera kugona kwemuviri uye kuita kwemitambo.
Pakave nezvidzidzo zvakawanda zvinoongorora kushanda kwealpha GPC pakutsungirira kwemuviri uye simba. A 2008 randomized, placebo-controlled, crossover study inosanganisira varume vanomwe vane ruzivo rwekudzivirira kudzidzira kwakaratidza kuti a-GPC inokanganisa kukura kwehomoni. Vatori vechikamu muboka rekuyedza vakapihwa 600 mg yealpha GPC 90 maminetsi vasati varamba kurovedza muviri.
Vatsvakurudzi vakaona kuti zvichienzaniswa nekutanga, peak kukura kwehomoni mazinga akawedzera 44-fold ne alpha GPC uye 2.6-fold ne placebo. Kushandiswa kweA-GPC kwakawedzerawo simba remuviri, nepeak bench press force inowedzera ne14% zvichienzaniswa ne placebo.
Pamusoro pekuwedzera simba remhasuru uye kusimba, kukura kwehomoni kunogona kusimudzira uremu, kusimbisa mapfupa, kugadzirisa mafungiro, uye kunatsiridza kunaka kwekurara.

4. Kuvandudza kupora kwesitiroko

Kutsvakurudza kwepakutanga kunoratidza a-GPC inogona kubatsira varwere vakave nesitiroko kana kuti kwenguva pfupi ischemic attack, inozivikanwa se "mini-stroke." Izvi zvinokonzerwa nekugona kwealpha GPC kuita senge neuroprotectant uye kutsigira neuroplasticity kuburikidza netsinga yekukura factor receptors.
Muchidzidzo che1994, vaongorori vekuItaly vakawana kuti alpha GPC yakavandudza kupora kwekuziva kune varwere vane acute kana madiki sitiroko. Mushure mekurohwa, varwere vakagamuchira 1,000 mg yealpha GPC nejekiseni kwemazuva 28, inoteverwa ne400 mg muromo katatu zuva nezuva kwemwedzi inotevera ye5.
Pakupera kwekuyedzwa, 71% yevarwere havana kuratidza kuderera kwekuziva kana amnesia, vaongorori vakashuma. Pamusoro pezvo, zvibodzwa zvevarwere paMini-Mental State Examination zvakavandudzika zvakanyanya. Pamusoro pezviwanikwa izvi, chikamu chezviitiko zvakashata zvinotevera kushandiswa kwealpha GPC yaive yakaderera uye vaongorori vakasimbisa kushivirira kwayo kwakanakisa.

5. Inogona kubatsira vanhu vane pfari

Chidzidzo chemhuka chakaburitswa muBrain Research muna 2017 chakanangana nekuongorora maitiro ealpha GPC kurapwa pakusagadzikana kwekuziva mushure mekubatwa nepfari. Vatsvakurudzi vakawana kuti apo makonzo akaiswa jekiseni ne-GPC mavhiki matatu mushure mekubatwa nekubatwa, komisheni yakavandudza cognitive basa uye yakawedzera neurogenesis, kukura kwetsinga tishu.
Chidzidzo ichi chinoratidza kuti alpha GPC inogona kubatsira muvarwere vepfari nekuda kwemhedzisiro yayo yeurouroprotective uye inogona kusimudzira pfari-induced cognitive impairment uye neuronal kukuvara.

Alpha GPC uye Choline

Choline chinhu chakakosha micronutrient inodiwa kune akawanda maitiro emuviri, kunyanya kushanda kwehuropi. Izvo zvinodiwa pakushanda kwakakodzera kweiyo kiyi neurotransmitter acetylcholine, iyo inoshanda senge anti-kuchembera neurotransmitter uye inobatsira tsinga dzedu kutaurirana.
Kunyangwe muviri uchiita mashoma echoline uri woga, isu tinofanirwa kuwana chikafu kubva muchikafu. Zvimwe zvekudya zvakakwirira mucholine zvinosanganisira chiropa chemombe, salmon, chickpeas, mazai, uye nyama yehuku. Zvisinei, mimwe mishumo inoratidza kuti choline kubva kune zvekudya haisi kunyatsobatwa nemuviri, ndicho chikonzero vamwe vanhu vanotambura nekushayikwa kwecholine. Izvi zvinodaro nekuti choline inogadziriswa zvishoma muchiropa, uye vanhu vane chiropa chakaremara havazokwanise kuibata.
Apa ndipo panopinda alpha GPC supplements. Dzimwe nyanzvi dzinokurudzira kushandisa choline supplements, zvakadai se-GPC, kuwedzera basa rehuropi uye kubatsira kuchengetedza ndangariro. Alpha GPC uye CDP choline inofungidzirwa kuti inonyanya kubatsira kumuviri nokuti yakafanana nenzira iyo choline inowanzoitika muzvokudya. Kungofanana necholine iyo inowanzotorwa kubva kune zvokudya zvatinodya, alpha GPC inozivikanwa nokuda kwekukwanisa kwayo kuyambuka ropa-brain chipingamupinyi painopinzwa, ichibatsira muviri kushandura choline muyose-yakakosha neurotransmitter acetylcholine.
Alpha GPC inzira ine simba yecholine. A 1,000 mg dose ye-GPC yakaenzana neinenge 400 mg yezvokudya choline. Kana, nemamwe mazwi, alpha GPC inenge 40% choline nehuremu.

A-GPC uye CDP Choline

CDP Choline, inozivikanwawo se cytidine diphosphate choline uye citicoline, isanganiswa inoumbwa necholine uye cytidine. CDP Choline inozivikanwa nekugona kwayo kubatsira kutakura dopamine muuropi. Kufanana nealpha GPC, Citicoline inokosheswa pakukwanisa kwayo kuyambuka chipingamupinyi cheropa-chepfungwa kana ichinge yapindwa, ichipa ndangariro-inosimudzira uye yekuziva-inosimudzira mhedzisiro.
Kunyange zvazvo alpha GPC ine inenge 40% choline nehuremu, CDP choline ine inenge 18% choline. Asi CDP choline inewo cytidine, inotangira nucleotide uridine. Inozivikanwa nekugona kwayo kuwedzera cell membrane synthesis, uridine zvakare ine cognitive-enhancing properties.
Ose ari maviri a-GPC neCDP choline anozivikanwa nekunzwisisa kwavo mabhenefiti, kusanganisira basa ravo mukutsigira ndangariro, kushanda kwepfungwa, uye kuisa pfungwa.

Kwaunowanikwa uye mashandisirwo

A-GPC yekuwedzera ndiyo inonyanya kushandiswa kuvandudza ndangariro uye kugona kwekuziva. Inogonawo kushandiswa kuvandudza kutsungirira kwemuviri uye kuita. Alpha GPC inowanikwa seyemumuromo chikafu chekuwedzera. Alpha GPC yekuwedzera iri nyore kuwana online kana kubva kune vatengesi. Iwe uchaiwana mune capsule uye hupfu mafomu. Zvigadzirwa zvakawanda zvine a-GPC zvinokurudzira kutora iyo yekuwedzera nechikafu kuti inyatsoshanda.
Suzhou Myland Pharm & Nutrition Inc. ndeye FDA-yakanyoreswa mugadziri inopa yemhando yepamusoro uye yakakwirira-kuchena alpha GPC hupfu.

PaSuzhou Myland Pharm takazvipira kupa zvigadzirwa zvemhando yepamusoro nemitengo yakanakisa. Yedu alpha GPC poda inoedzwa zvakasimba kuchena uye potency, kuve nechokwadi kuti iwe unowana yemhando yekuwedzera yaunogona kuvimba nayo. Kunyangwe iwe uchida kutsigira hutano hweserura, kuwedzera immune system yako kana kuwedzera hutano hwese, yedu alpha GPC hupfu ndiyo sarudzo yakakwana.

Iine makore makumi matatu echiitiko uye ichisundwa nehunyanzvi hwepamusoro uye akakwenenzverwa zvakanyanya R&D mazano, Suzhou Myland Pharm yakagadzira mhando yezvigadzirwa zvemakwikwi uye ive yekuvandudza hupenyu hwesainzi yekuwedzera, tsika synthesis uye kugadzira masevhisi kambani.

Uye zvakare, Suzhou Myland Pharm zvakare iri FDA-yakanyoreswa mugadziri. Zviwanikwa zvekambani zveR&D, zvivakwa zvekugadzira, uye zviridzwa zvekuongorora ndezvemazuva ano uye zvinoshanda, uye zvinogona kugadzira makemikari kubva kumamirigiramu kusvika kumatani muchiyero, uye zvinoenderana neISO 9001 zviyero uye kugadzirwa kweGMP.
A-GPC inozivikanwa kuva hygroscopic, zvichireva kuti inotora hunyoro kubva kumhepo yakapoteredza. Nechikonzero ichi, ma supplements anofanirwa kuchengetwa mumidziyo isina mhepo uye haifanirwe kuratidzwa kumhepo kwenguva yakareba.

Pfungwa dzekupedzisira

Alpha GPC inoshandiswa kuendesa choline kuhuropi mukati meropa-brain barriers. Iyo inotangira kune acetylcholine, neurotransmitter inosimudzira hutano hwekuziva. Alpha GPC yekuwedzera inogona kushandiswa kubatsira hutano hwako hwekuziva nekuvandudza ndangariro, kudzidza, uye kuisa pfungwa. Tsvagiridzo inoratidzawo kuti a-GPC inobatsira kuwedzera simba remuviri uye simba remhasuru.