Muhupenyu hwedu hwakabatikana hwezuva nezuva, zvakajairika kunzwa kushushikana, kunetseka, uye kunyange kusuwa nguva nenguva.Manzwiro aya anogona kukanganisa hutano hwedu hwepfungwa, kazhinji achitisiya tichitsvaga nzira dzekusimudza mweya yedu.Kunyange paine nzira dzakawanda dzekusimudzira manzwiro edu, chinhu chakakosha chekufunga nezvacho iurotransmitter, serotonin.Kazhinji inonzi "homoni yekunzwa-kunakirwa," serotonin inoita basa rakakosha mukudzora manzwiro edu, pfungwa, uye kugara zvakanaka.
Saka, chii chinonzi serotonin?Serotonin, inozivikanwawo se serotonin, ikemikari inoshanda seyeurotransmitter, zvichireva kuti inoshanda senhume inotakura zviratidzo pakati pemaseru etsinga muuropi.Inonyanya kubudiswa mu brain brain, asi inowanikwawo mune dzimwe nzvimbo dzemuviri, dzakadai sematumbo.Inowanzonzi "happy hormone" kana "bliss molecule" nokuti inobatanidzwa nemanzwiro emufaro, kugutsikana, uye kugara zvakanaka.
Kana serotonin yangogadzirwa, inoburitswa mumasynapses, kana maburi pakati pemasero etsinga.Inobva yasunga kune chaiwo mareceptor pamusoro pemasero etsinga ari pedyo.Iyi inosunga nzira inofambisa kutaurirana pakati pemaseru uye inobatsira kutumira masaini.
Serotonin inoita basa rakakosha mukudzora mabasa akasiyana siyana mumiviri yedu, kusanganisira kurara, kuda kudya, kugaya, uye ndangariro.Inobatanidzwa mukugadzirisa manzwiro edu uye inobatsira kuchengetedza mafungiro akagadzikana.Serotonin mazinga muuropi hwedu anogona kukanganisa zvakanyanya hutano hwedu hwepfungwa.
Serotonin haingokanganisa hutano hwedu hwepfungwa uye hwepfungwa, asi inoitawo basa rakakosha muhutano hwedu hwepanyama.Serotonin inodzora kutenderera kwedu kwekurara uye huwandu hwekurara hwese.Kukwana kweserotonin muuropi kunokurudzira kurara kwakadzikama, nepo kuderera kunogona kutungamirira kumatambudziko ekurara akadai sekushaya hope.
Serotonin inonzi neurotransmitter muuropi ine basa rekugadzirisa mafungiro, mafungiro, uye kurara.Inowanzonzi kemikari ye "kunzwa-zvakanaka" nokuti inobatsira kuunza kunzwa kwekugara zvakanaka.Serotonin inobata basa rinokosha mukuchengetedza kuenzanisa muuropi, uye chero kukanganisa mumazinga ayo kunogona kutungamirira kune zvakasiyana-siyana zvehutano hwepfungwa, kusanganisira kufunganya.
Tsvagiridzo yakawana kuti vanhu vane dambudziko rekushushikana vanowanzove nekusaenzana kweserotonin mazinga muhuropi hwavo.Yakaderera serotonin mazinga akabatanidzwa kune yakawedzera njodzi yekushushikana kusagadzikana, sezvo serotonin inobatsira kudzora mafungiro uye kufunganya.Kana mazinga e serotonin akadzikira, vanhu vanogona kuona zviratidzo zvakaita sekushatirwa, kusagadzikana, uye kushushikana kwakanyanya.
Selective serotonin reuptake inhibitors (SSRIs) mishonga inoderedza kushungurudzika inowanzoshandiswa kurapa vanhu vane zvinetso zvekuzvidya mwoyo.Iyi mishonga inoshanda nekuwedzera mazinga e serotonin muuropi.Nokuita kudaro, SSRIs inobatsira kudzorera kuenzana kweserotonin uye kuderedza zviratidzo zvekuzvidya mwoyo.Zvisinei, zvakakosha kuziva kuti serotonin inongova chikamu chimwe chete chenzira dzakaoma dzeneural dzakabatana nezvinetso zvekuzvidya mwoyo, uye zvimwe zvinhu zvakadai se genetics, zvakatipoteredza uye zviitiko zvehupenyu zvinobatsirawo pakuvandudzwa kwemamiriro aya.
Tsvagiridzo inoratidza kuti kuita kurovedza muviri nguva dzose kunogona kuwedzera kugadzirwa kweserotonin muuropi.Kwete chete kurovedza muviri kunosimudzira kuburitswa kweserotonin, kunowedzerawo kunzwisiswa kwehuropi kune iyi neurotransmitter, nekudaro kuvandudza manzwiro uye kuderedza kusagadzikana.
Pamusoro pezvo, kudzidzira maitiro ekudzvinyirira akadai sekufungisisa, kufema zvakanyanya maekisesaizi, uye kufunga kunogona kubatsira kuwedzera serotonin mazinga uye kuderedza kushushikana zviratidzo.Aya maitiro anokurudzira kuzorora uye kudzikama, zvichibvumira uropi kuburitsa uye kushandisa serotonin zvakanyanya.
1. Mafungiro akakwirira uye mafungiro akagadzikana
Serotonin inozivikanwa nekukwanisa kwayo kugadzirisa mafungiro.Iyo yakasikwa mood stabilizer inosimudzira pfungwa yekugara zvakanaka uye kugutsikana uku ichideredza kufunganya uye kushushikana.Yakakwana serotonin mazinga akakosha mukudzivirira kusagadzikana kwemafungiro akadai sekuora mwoyo, kufunganya, uye bipolar disorder.Nekuwedzera mazinga e serotonin, vanhu vanogona kuwana kugadzikana kwemanzwiro, kuwedzera kwekunzwa kugadzikana, uye maonero akanaka ehupenyu.
2. Kuvandudza basa rekuziva
Pamusoro pemhedzisiro yayo pamafungiro, serotonin inoitawo basa rakakosha mukuziva basa.Iyi neurotransmitter inofambisa kutaurirana pakati pemasero ehuropi, inotsigira kuumbwa kwendangariro uye kurangarira.Yakakwana serotonin mazinga anobatanidzwa nekuwedzera kutarisa, kutarisisa, uye kugona kwekuziva.Kuve nechokwadi chekupihwa kwehutano hweserotonin kunogona kubatsira kuvandudza kugadzikana kwepfungwa, kuvandudza kudzidza, uye kuderedza kuderera kwekuziva kunoenderana nekukwegura.
3. Mutemo wekuda kudya uye uremu
Serotonin inobata zvakanyanya uye inobatsira kudzora havi yedu uye maitiro ekudya.Serotonin mazinga muuropi anopesvedzera maonero atinoita nzara nekuzara, zvichikanganisa sarudzo dzedu dzekudya uye kutonga kwechikamu.Pamusoro pezvo, serotonin inogadzirwawo muura, uye kushomeka kweserotonin kunogona kutungamira mukudyisa, kushuva chikafu chine makabhohaidhiretsi, uye kuwedzera njodzi yekufutisa.Nekuchengetedza yakakwana serotonin mazinga, tinokwanisa kubata zvirinani chishuwo chedu, kuita sarudzo dzine hutano hwekudya, kuderedza kushuva, uye kuchengetedza huremu hune hutano.
4. Kurudzira kurara kwakadzikama
Kurara kwakanaka kunokosha pautano hwemuviri nepfungwa.Serotonin inoita basa rakakosha mukusimudzira maitiro ekurara ane hutano.Inobatsira kudzora kutenderera kwekurara-kumuka, kutibvumira kurara nekukurumidza, kurara kwenguva refu, uye kuwana kudzoreredza kurara.Kusakwana kweserotonin mazinga kunogona kukonzera kushaya hope, kukanganisa kurara, uye kurara masikati.Nekuona kuti serotonin yakakwana inogadzirwa, tinogona kuvandudza kunaka kwekurara kwedu uye kumuka tichinzwa kurodzwa uye kusimba.
5. Tsigira utano hwekudya
Pamusoro pemigumisiro yayo pauropi, serotonin inokanganisawo hurongwa hwekudya.Inenge 90% ye serotonin inowanikwa mumatumbo uye ine basa rekugadzirisa gastrointestinal basa.Inobatsira kudzora mafambiro ematumbo, inosimudzira kugaya zvakanaka, uye inobatsira kuhutano hwese hwematumbu.Kusaenzana kweSerotonin kwakabatana nekusagadzikana kwekugaya senge irritable bowel syndrome (IBS) uye chirwere chinoputika (IBD).Nekuchengetedza yakakwana serotonin mazinga, tinogona kusimudzira hutano hwematumbo uye kuderedza njodzi yematambudziko ekugaya.
Dzidza nezvezviratidzo zvekushomeka:
●Kuora mwoyo, kuora mwoyo
●Kutadza kurara
●Kusapora ronda
● ndangariro dzisina kunaka
● Matambudziko ekugaya
● Zvipingamupinyi zvezvitupa
●Kushaya kudya
Ziva chikonzero:
●Kusadya zvakanaka: kunonyanya kusanganisira kudya kumwe chete, kudya kusina zvinovaka muviri, uye bulimia.
●Malabsorption: Mamwe mamiriro ezvinhu, akadai sechirwere checeliac uye chirwere chinoputika, chinogona kukanganisa kunwa kwemuviri kwezvokudya.
●Zvinodhaka: Mimwe mishonga inogona kukanganisa kubatwa kana kushandiswa kwezvimwe zvinovaka muviri.
● Kusagadzikana mupfungwa: kuora mwoyo, kuzvidya mwoyo.
SSRIs inoshanda nekuwedzera serotonin mazinga muuropi.Serotonin inonzi neurotransmitter inoita basa rakakosha mukudzora manzwiro, mafungiro, uye hutano hwese.Nekudzivirira kudzoreredzwa kweserotonin, SSRIs inova nechokwadi chekuti inoramba iri mumasynapses kwenguva refu, nekudaro ichiwedzera mhedzisiro yayo pakugadzirisa mafungiro.
Mashandisiro anoita SSRIs
SSRIs inoshanda nekudzivisa kudzokororwa kweserotonin muuropi.Iyo meshini inosanganisira SSRIs inosunga kune serotonin transporter, ichiidzivirira kubva kunotora serotonin kudzokera mumasero etsinga.Nekuda kweizvozvo, serotonin inoramba iri mu synaptic cleft pakati pemaseru etsinga, ichiwedzera kutapurirana kwayo uye kukwidziridza maitiro ayo anogadzirisa maitiro.
Zvakakosha kuziva kuti SSRIs haiwedzere serotonin kugadzirwa;asi ivo vanoshandura kuwanikwa uye kushanda kweserotonin iripo.Nekubvumidza serotonin kuti irambe iri mu synaptic cleft kwenguva refu, SSRIs inobatsira kubhadhara yakaderera serotonin mazinga uye kudzoreredza mwero kuuropi.
Zvakakodzera kutaura kuti tianeptine hemisulfate monohydrate is selective serotonin reuptake enhancer (SSRE), zvinoreva kuti inowedzera kudzokororwa kweserotonin muuropi, nokudaro kusimbisa hippocampal neurons Synaptic plasticity kuvandudza mafungiro uye manzwiro.
SSRIs uye mhedzisiro
Kunyange zvazvo SSRIs inowanzoonekwa yakachengeteka uye inobvumirwa zvakanaka, inogona kuuya nemimwe migumisiro.Zvinowanzoitika zvinogona kusanganisira kusvotwa, dzungu, kutemwa nemusoro, kunyangwe izvi zvinogona kusiyana pamunhu nemunhu.Zvakakosha kuti varwere vataure chero zvinonetsa kana mhedzisiro kune vashandi vavo vekurapa kuitira kuti kunyatsotarisisa uye kugadzirisa kwakakodzera kunogona kuitwa, kana zvichidikanwa.
Mubvunzo: Pane here mararamiro emararamiro anogona kuderedza mazinga e serotonin?
A: Hongu, kunwa doro zvakanyanyisa, kudya kwakashata, kushaya maekisesaizi, kusagadzikana kusingaperi, uye mimwe mishonga yakadai semishonga inoderedza kuora mwoyo inogona kukanganisa mazinga e serotonin.
Mubvunzo: Ndeipi inofanira kunge iri nzira yekusimudzira serotonin mazinga?
A: Maitiro akazara anofanirwa kugamuchirwa kuti awedzere serotonin mazinga ega.Izvi zvinosanganisira kuchengetedza kudya kwakadzikama, kuita maekisesaizi nguva dzose, kuwana chiedza chezuva chakakwana, kunyatsogadzirisa kushushikana mupfungwa, uye kufunga nezvekuwedzera uchitungamirirwa nenyanzvi kana zvichidiwa.
Disclaimer: Ichi chinyorwa ndecheruzivo rwese chete uye hachifanirwe kutorwa sechero zano rekurapa.Imwe yeruzivo rweblog post runobva kuInternet uye haina hunyanzvi.Iyi webhusaiti inongova nebasa rekugadzirisa, kufomatidza uye kugadzirisa zvinyorwa.Chinangwa chekuendesa rumwe ruzivo hachirevi kuti unobvumirana nemaonero ayo kana kusimbisa uchokwadi hwezvirimo.Nguva dzose bvunza nyanzvi yezvehutano usati washandisa chero chekuwedzera kana kuita shanduko kuhutano hwako hwehutano.
Nguva yekutumira: Oct-07-2023
