Nekukura kwenharaunda, vanhu vari kuramba vachinyanya kutarisisa nyaya dzehutano. Nhasi ndinoda kukuzivisai nezvechirwere cheAlzheimer, chinova chirwere cheuropi chinoramba chichikura chinokonzera kurasikirwa nendangariro nedzimwe pfungwa.
Chokwadi
Chirwere cheAlzheimer, rudzi rwakajairika rwechirwere chepfungwa, izwi rinowanzo shandiswa kureva ndangariro nekurasikirwa nepfungwa.
Chirwere cheAlzheimer chinouraya uye hachina mushonga. Chirwere chisingaperi chinotanga nekurasikirwa nendangariro uye pakupedzisira chinozokonzera kukuvara kwakanyanya kweuropi.
Chirwere ichi chakatumidzwa zita raDr. Alois Alzheimer. Muna 1906, chiremba wepfungwa akaita ongororo yeuropi hwemukadzi akafa mushure mekurwara nekutaura, maitiro asingatarisirwi uye kurasikirwa nendangariro. Dr. Alzheimer akawana ma plaque e amyloid uye ma neurofibrillary tangles, ayo anoonekwa sezviratidzo zvechirwere ichi.
Zvinhu Zvinopesvedzera:
Zera - Mushure memakore makumi matanhatu nemashanu, mukana wekuwana chirwere cheAlzheimer unowedzera kaviri makore mashanu ega ega. Kune vanhu vazhinji, zviratidzo zvinotanga kuonekwa mushure memakore makumi matanhatu.
Nhoroondo Yemhuri - Zvinhu zvinokonzerwa nemajini zvine basa guru munjodzi yemunhu.
Kukuvara Musoro - Panogona kunge paine hukama pakati pechirwere ichi nekukuvara kunowanzoitika kana kurasikirwa nepfungwa.
Hutano hwemwoyo - Zvirwere zvemwoyo zvakaita seBP yakakwira, cholesterol yakakwira uye chirwere cheshuga zvinogona kuwedzera njodzi yekuora mwoyo kwetsinga dzeropa.
Ndezvipi zviratidzo zvishanu zvinonyevera zvechirwere cheAlzheimer?
Zviratidzo zvinogona kuitika: kurasikirwa nendangariro, kudzokorora mibvunzo nemashoko, kusanzwisisa, kuisa zvinhu panzvimbo yazvo, kuchinja kwemanzwiro nehunhu, kuvhiringidzika, kufungidzira uye kutya, kushaya chido, pfari, kuoma kumedza
Chii chakasiyana pakati pechirwere chepfungwa (dementia) nechirwere cheAlzheimer?
Dementia nechirwere cheAlzheimer zvese zvirwere zvine chekuita nekuderera kweruzivo rwepfungwa, asi pane musiyano pakati pazvo.
Dementia chirwere chinosanganisira kudzikira kwekushanda kwepfungwa kunokonzerwa nezvikonzero zvakasiyana-siyana, zvinosanganisira zviratidzo zvakaita sekurasikirwa nendangariro, kusakwanisa kufunga zvakanaka, uye kusakwanisa kusarudza zvakanaka. Chirwere cheAlzheimer ndicho chirwere chinowanzoonekwa chedementia uye ndicho chinokonzera ruzhinji rwevanhu vane dementia.
Chirwere cheAlzheimer chirwere chinoenderera mberi nekuora kwetsinga chinowanzo rova vanhu vakuru uye chinoratidzwa nekusagadzikana kwemapuroteni muuropi, zvichikonzera kukuvara kwetsinga nerufu. Dementia izwi rakakura rinosanganisira kudzikira kwekuziva kunokonzerwa nezvikonzero zvakasiyana-siyana, kwete chirwere cheAlzheimer chete.
Fungidziro dzenyika
Sangano reCenters for Disease Control and Prevention rinofungidzira kuti vanhu vanosvika mamiriyoni matanhatu nehafu vekuAmerica vane chirwere cheAlzheimer. Chirwere ichi ndicho chikonzero chechishanu chikuru cherufu muvanhu vakuru vane makore anopfuura makumi matanhatu nemashanu muUnited States.
Mari yekutarisira vanhu vane chirwere cheAlzheimer kana zvimwe zvirwere zvepfungwa muUnited States inofungidzirwa kuva mabhiriyoni mazana matatu nemakumi mana nemashanu emadhora muna 2023.
chirwere cheAlzheimer's chinotanga nekukurumidza
Chirwere cheAlzheimer chinowanzo tanga chirwere chepfungwa chisingawanzoitiki chinowanzo bata vanhu vari pasi pemakore makumi matanhatu nemashanu.
Chirwere cheAlzheimer chinowanzotanga mumhuri.
Tsvagiridzo
Kurume 9, 2014—Muchidzidzo chekutanga cherudzi urwu, vaongorori vanoti vakagadzira bvunzo yeropa inogona kufanotaura nemazvo kana vanhu vane hutano vachabatwa nechirwere cheAlzheimer.
Mbudzi 23, 2016 – Mugadziri wemishonga wekuAmerica Eli Lilly akazivisa kuti achagumisa kuyedzwa kwekiriniki kwechikamu chechitatu chemushonga wake weAlzheimer's solanezumab. "Kuwanda kwekuderera kwepfungwa hakuna kuderera zvakanyanya muvarwere vakarapwa nesolanezumab zvichienzaniswa nevarwere vakarapwa ne placebo," kambani yakadaro mumashoko ayo.
Kukadzi 2017 - Kambani yemishonga Merck yakamisa kuyedzwa kwemushonga wayo weAlzheimer's verubecestat mushure mekunge ongororo yakazvimirira yawana kuti mushonga uyu "haushande zvakanaka."
Kukadzi 28, 2019 - Magazini inonzi Nature Genetics yakaburitsa chidzidzo chakaburitsa mhando ina itsva dzemajini dzinowedzera njodzi yechirwere cheAlzheimer. Majini aya anoita seanoshanda pamwe chete kudzora mashandiro emuviri anokanganisa kukura kwechirwere ichi.
Kubvumbi 4, 2022 - Chidzidzo chakaburitswa chinyorwa chino chakawana mamwe majini makumi mana nemaviri ane chekuita nekukura kwechirwere cheAlzheimer.
Kubvumbi 7, 2022 — Sangano reCenters for Medicare and Medicaid Services rakazivisa kuti richaganhurira kufukidzwa kwemushonga weAlzheimer unokakavadzana uye unodhura weAduhelm kuvanhu vari kutora chikamu mumiedzo yekiriniki inokodzera.
Chivabvu 4, 2022 – FDA yakazivisa kubvumidzwa kwebvunzo itsva yekuongorora chirwere cheAlzheimer. Ndiyo bvunzo yekutanga yekuongorora in vitro inogona kutsiva zvishandiso zvakaita sePET scans dziri kushandiswa pari zvino kuongorora chirwere cheAlzheimer.
30 Chikumi, 2022 – Masayendisiti akawana jini rinoita serinowedzera njodzi yemukadzi yekubatwa nechirwere cheAlzheimer, zvichipa zviratidzo zvitsva zvekuti nei vakadzi vari ivo vanowanzoonekwa vaine chirwere ichi kupfuura varume. Jini iri, O6-methylguanine-DNA-methyltransferase (MGMT), rine basa rakakosha mukukwanisa kwemuviri kugadzirisa kukuvara kweDNA muvarume nevakadzi. Asi vaongorori havana kuwana hukama pakati peMGMT nechirwere cheAlzheimer muvarume.
Ndira 22, 2024—Chidzidzo chitsva mumagazini yeJAMA Neurology chinoratidza kuti chirwere cheAlzheimer chinogona kuongororwa "nekunyatsorongeka" nekuona puroteni inonzi phosphorylated tau, kana kuti p-tau, muropa remunhu. Chirwere chisingaperi, chinogona kuitwa kunyangwe zviratidzo zvisati zvatanga kuoneka.
Nguva yekutumira: Chikunguru-09-2024
