5-amino-1-methylquinolinium iodide CAS Nha.:42464-96-0 98.0% kuchena min. | mugadziri wezvigadzirwa zvekuwedzera
Product Parameters
| Product name | 5-amino-1-methylquinolinium iodide |
| Rimwe zita | NNMTi5-Amino-1-mq ayodhidhi 5-amino-1-methylquinolinium iodide 5-AMINO-1-METHYLQUINOLIN-1-IUM IODIDE 5-Amino-1-methylquinolin-1-iumiodide 1-methylquinolin-1-ium-5-amine;iodide 5-Amino-1-methyl-1-quinolinium Iodide |
| CAS Nha. | 42464-96-0 |
| Molecular formula | C10H11IN2 |
| Molecular uremu | 286.11 |
| Kuchena | 98% |
| Chitarisiko | Brown kusvika kune yakatsvuka tsvuku yakaoma |
| Packing | 1kg/bag, 25kg/barrel |
| Application | Dietary Supplement Raw Material |
Product sumo
NNMTi is enzyme yakanyanyisa panguva yekuchembera kweskeletal tsandanyama uye inosanganiswa nekugadziriswa kweNAD + kukuvara kwenzira, dysregulated sirtuin1 chiitiko, uye yakawedzera tsandanyama stem cell senescence. NNMTi inosimudzira myoblast kusiyanisa in vitro uye inosimudzira fusion uye kuvandudzwa kwemhasuru stem masero mumakonzo akura. NNMTi zvakare inhibitor ine simba ye nicotinamide N-methyltransferase (NNMT) (IC50 = 1.2 μM), inosarudza inosunga kuNNMT substrate inosunga masasi esaiti. NNMTi inosimudzira myoblast kusiyanisa in vitro uye inosimudzira fusion uye kuvandudzwa kwemhasuru stem masero mumakonzo akura. Pakati pavo, iyo cytosolic enzyme nicotinamide N-methyltransferase (NNMT) ichangobva kuwanikwa kuti itonge mazinga e nicotinamide precursors anodiwa kuNAD + biosynthesis, uye nekudaro inoita basa rakakosha mukugadzirisa iyo NAD + salvage nzira uye cellular metabolism.
Feature
(1) Kuchena kwepamusoro: NNMTi inogona kuwana zvigadzirwa zvehutsanana kuburikidza nekunatswa kugadzirwa kwemaitiro. Kuchena kwepamusoro kunoreva kuti bioavailability iri nani.
(2) Targeting: NNMTi inonyatso tarisa iyo NNMT enzyme uye inogona kunyatso kuvharidzira basa rayo, nokudaro ichikanganisa nzira yemagetsi ye nicotinamide.
(3) Kugadzikana: NNMTi ine kugadzikana kwakanaka uye inogona kuchengetedza basa rayo nekuita pasi pemamiriro akasiyana-siyana uye kuchengetedza mamiriro.
(4) Tarisiro yebudiriro: Nekuda kwehunhu hwakasiyana hweNNMT, kusimukira kwayo kwakagamuchira kutariswa kwakapararira uye ine tsvakiridzo yakakura uye tarisiro yekushandisa.
Applications
NNMTi is nicotinamide N-methyltransferase (NNMT) inhibitor inokurudzira myoblast kusiyana. NNMTi inogonawo kushandiswa sekuwedzera kwekubatsira kuderedza uremu nemafuta uye kuvandudza mafuta echiropa.
