Uri kutsvaga yemhando yepamusoro Oleoylethanolamide (OEA) poda mutengesi? Nezvazvinogoneka zvehuremu manejimendi uye hutano hwese, hazvishamisi kuti vanhu vazhinji vanofarira mukomboni iyi. Nekudaro, kana uchitenga OEA poda, zvakakosha kuti uve nechokwadi chekuti uri kuwana chemhando yepamusoro chigadzirwa chinoenderana nezvido zvako. Saka kutenga mhando oleoylethanolamide poda inoda kunyatsotariswa kwemupi, kuchena, potency, fomu, uye mutengo. Nekufunga zvinhu izvi uye kutsvaga zano rehunyanzvi, unogona kuita sarudzo ine ruzivo uye kusarudza kutsigira bhizinesi rako nehupfu hwemhando yepamusoro yeOEA.
Munharaunda yezvokurapa, kune asingaverengeki maacronyms uye mazwi anogona kuvhiringidza kune avo vasina kujairana nemunda. Vanhu vazhinji vanogona kunge vasingazive izwi iri:Oleylethanolamide (OEA). Chii chaizvo chinonzi OEA kubva pakuona kwekurapa? Nei zvichikosha kuinzwisisa?
Ngatinzwisise muchidimbu chimiro uye zvivakwa zveOEA!
Chimiro
Oleic acid ethanolamide, kana Oleoylethanolamide (OEA), inhengo ye endogenous cannabinoids. Icho chikamu chechipiri amide chinoumbwa ne lipophilic oleic acid uye hydrophilic ethanolamine. OEA zvakare inongoitika lipid molecule mune dzimwe mhuka uye chirimwa tishu. Inowanikwa zvakanyanya mumhuka nezvirimwa zvinyama zvakaita secocoa poda, soya beans, uye nzungu, asi zvirimo zvakaderera zvakanyanya. Chete kana nharaunda yekunze yachinja kana chikafu chikakurudzirwa, matishu emasero emuviri Ipapo ndipo paizogadzirwa zvakawanda zvechinhu ichi.
Nature
Patembiricha yemumba, OEA igobvu chena uye inonyungudika inosvika 50°C. Inonyungudika zviri nyore muzvinonyungudutsa zvinodhaka zvakadai semethanol uye ethanol, zvinonyungudika zviri nyore mune zvisiri-polar zvinonyungudutsa senge n-hexane uye ether, uye zvisinganyungudika mumvura. OEA iamphiphilic molecule yagara ichishandiswa seyakagadziriswa uye detergent muindasitiri yemakemikari. Nekudaro, kumwe kutsvagurudza kwakawana kuti OEA inogona kushanda se lipid inosaina molecule mune gut-brain axis uye kuratidza nhevedzano yezviitiko zvipenyu mumuviri, zvinosanganisira: kudzora havi, kuvandudza lipid metabolism, kusimudzira ndangariro uye cognition uye mamwe mabasa. Pakati pavo, mabasa eOEA ekudzora chishuwo uye kuvandudza lipid metabolism akagashira zvakanyanya.
Oleylethanolamide (OEA) ndeye yakasikwa mafuta acid inotorwa mudumbu mudiki. Iyo ndeyekirasi yemakomisheni anozivikanwa se endocannabinoids. Endogenously inogadzirwa Oleoylethanolamide (OEA) inongoitika lipid molecule inoita basa rakakosha mune akasiyana maitiro emuviri mumuviri. Inotsanangurwa sebioactive lipid uye inhengo ye endocannabinoid system, yakaoma network yekusaina mamorekuru uye receptors inobatanidzwa mukugadzirisa mabasa mazhinji emuviri, kusanganisira kuda kudya, Metabolism, kurwadziwa, uye kuzvimba.
OEA inogona kudzora kudya kwekudya uye simba homeostasis nekuita peroxisome proliferator-activated receptor-α. Pamusoro pezvo, OEA inoratidza zvimwe zviitiko zvine chekuita nehutano, kusanganisira modulating converter chiitiko mu lysosomal-to-nuclear signing pathway yakabatana nekugara kwenguva refu mutemo uye kudzivirira tsinga dzinodzora hunhu hwekuora mwoyo.
Tsvagiridzo ichangoburwa inoratidzawo kuti OEA inogona kuve neuroprotective mhedzisiro. Mumienzaniso yemhuka, yakawanikwa ichideredza kukuvadzwa kubva mukurohwa uye kukuvara kwehuropi.
Iyo yekudzora mhedzisiro yeOEA inonzi inoenderana nekusunga kwayo kuPPARα, iyo inodzikira neiyo retinoid X receptor (RXR) uye inoimisa sechinhu chine simba chinyorwa chinobatanidzwa mukubatanidza simba homeostasis, lipid metabolism, autophagy, uye kuzvimba. zvinonangwa pasi pemvura.
Nekudaro, zvirimo zveOEA zvakaderera zvakanyanya uye zvakaoma kuwana zvakananga kubva kune zvekudya, saka mamwe masosi eOEA anoda kuvandudzwa. Pakati pavo, makemikari synthesis uye biological shanduko maitiro ndiwo arizvino masosi ekuwana OEA. Pakati pavo, Suzhou Mailun Biotechnology inogadzira yakakwirira-kuchena, yemhando yepamusoro OEA kuburikidza nemakemikari synthesis.
Iyo synthesis process yeOEA inonyanya kusanganisira maitiro maviri: the synthesis ye phospholipid-yakatorwa N-oleoylphosphatidylethanolamine (NOPE) uye yakazotevera shanduko yeNOPE kuita OEA. Iyo shunt yeNAS kana NAT inobatanidzwa mukuumbwa kweNOPE, nepo OEA inogona kugadzirwa nenzira dzakawanda, pakati peiyo phospholipase D (PLD) ndiyo nzira yakananga.
PEA, pfupi yePalmitoylethanolamide (PEA), is a fatty acid amide iyo inogadzirwa nemuviri mumhinduro kune kuzvimba uye kurwadziwa. Inowanikwawo mune zvimwe zvekudya, kunyanya izvo zvakapfuma mumafuta ane hutano senge mazai, soya beans, uye nzungu. PEA yakadzidzwa kune yayo inogona anti-kuzvimba uye analgesic mhedzisiro, ichiita iyo yakakurumbira yekuwedzera kune vanhu vanobata nekurwadziwa kusingaperi, arthritis, uye mamwe mamiriro ekuzvimba.
OEA (kana oleoylethanolamide), kune rumwe rutivi, lipid molecule inogadzirwa mudumbu diki. Basa rayo guru nderekugadzirisa chido uye uremu hwemuviri nekubatana ne endocannabinoid system. Inozivikanwa nekugona kwayo kukurudzira kuguta uye kuderedza kudya, Oleoylethanolamide (OEA) isarudzo inovimbisa kune avo vanotarisa kutsigira uremu uye hutano hwekudya.
Imwe yemisiyano mikuru pakati pePEA ne Oleoylethanolamide(OEA) ndiyo nzira yavo yekuita uye masisitimu ari mumuviri wavanonongedza. PEA inonyanya kuita nzira dzekuzvimba uye kuona kurwadziwa, nepo OEA inotarisa pakutonga kwechido uye chiyero chesimba. Musiyano uyu wakakosha kana uchifunga zvingangobatsira zvekomboni yega yega uye kuti ingashandiswa sei kugadzirisa mamwe matambudziko ehutano.
Panyaya yezvingangobatsira zvehutano, PEA yakadzidzwa nezvebasa rayo mukurapa marwadzo asingagumi senge fibromyalgia, neuropathy, uye sciatica. Iyo anti-inflammatory properties inoita kuti ive sarudzo yakakosha kune vanhu vari kutsvaga imwe nzira yepanyama kune tsika dzekugadzirisa marwadzo echinyakare. Pamusoro pezvo, PEA inoratidza chivimbiso mukutsigira hutano hweganda uye immune function, ichiwedzera kuwedzera kwayo inogona kushandiswa mukusimudzira hutano hwese.
Kune rimwe divi, basa reOleoylethanolamide (OEA) mukutonga kwechido uye huremu manejimendi rakakwezva kutarisa mukugadzirisa kufutisa uye metabolic kusagadzikana. Tsvagiridzo inoratidza kuti Oleoylethanolamide (OEA) inogona kubatsira kudzora kuchiva kwechikafu, kuderedza kudyisa, uye kutsigira metabolism ine hutano, ichiita chishandiso chakakosha kune vanhu vari kutsvaga kuwana uye kuchengetedza huremu hune hutano. Uyezve, kudyidzana kweOEA ne endocannabinoid system inosimbisa inogona kukanganisa mafungiro uye manzwiro ekudya maitiro.
Kunyangwe Palmitoylethanolamide (PEA) uye Oleoylethanolamide (OEA) vane mhedzisiro dzakasiyana uye zvingangobatsira, zvakakosha kuti uzive kuti ivo havana kuwirirana. Muchokwadi, vamwe vanhu vanogona kuwana kukosha mukubatanidza ese ari maviri makomisheni muhutano hwavo maitiro ekugadzirisa akawanda ehutano hwavo. Semuyenzaniso, vanhu vane kurwadziwa kusingaperi uye nyaya dzehuremu vanogona kubatsirwa kubva kuPEA's anti-inflammatory properties pamwe neOEA's appetite-regulating effects.
Appetite Control uye Weight Management
Mumakore achangopfuura, oleoylethanolamide yakawedzera kufarirwa sechikafu chekuwedzera uremu. Tsvagiridzo inoratidza kuti OEA inogona kubatsira kuderedza kudya, zvichitungamira mukudzikiswa kwekudya uye nekuzotevera uremu.
OEA chinhu chakakosha chekudya inhibitor chine basa guru kubatsira kuderedza kufutisa. Intraperitoneal jekiseni reOEA rinogona kunyatso kudzikisa kudya kwekudya uye kuwedzera huremu mumakonzo. Iyo huru yekurasikirwa nehuremu mhedzisiro yeOEA ndeyekuti inogona kukurudzira kunzwa kwekuguta, nekudaro kudzora kudya kwakanyanya. Kuwedzera kumwe kuungana kweOEA pakudya kwemakonzo akajairwa kana akafuta kunogona kuderedza havi yembeva nehuremu.
OEA haingogone kuvharidzira kunyura kwemafuta emudumbu, asi zvakare inomhanyisa iyo beta oxidation yemafuta acids nekusimudzira iyo hydrolysis ye triglycerides mumatishu eperipheral (chiropa nemafuta), pakupedzisira ichidzikisa kuunganidzwa kwemafuta uye kuwana huremu kudzora.
Pamusoro pezvo, OEA inoshanda paPPAR receptors mudumbu diki, zvichibatsira kuderedza kudya uye kuwedzera kuparara kwemafuta mumuviri. Iyi metabolic mhedzisiro yeOEA inoguma nekuwedzera kwekushandisa simba, izvo zvakakosha pakurasikirwa nehuremu.
Pamusoro pekudzora kudya, OEA poda inotsigira hutano hwemetabolism. Tsvagiridzo inoratidza kuti OEA inogona kubatsira kuwedzera simba rekushandisa remuviri, zvichigona kuwedzera metabolic rate. Nekusimudzira lipolysis nekuvandudza kushandiswa kwesimba, OEA poda inogona kutsigira avo vanotarisa kuchengetedza huremu hune hutano uye metabolism.
Emotion uye stress management
Oleoylethanolamide (OEA) yakaratidza kuve inoshanda mukudzikisa kushushikana uye kusagadzikana mazinga mumuviri. OEA inobatsira kudzora kugadzirwa kwehomoni dzekushushikana senge cortisol, nekudaro kuderedza kusagadzikana uye kushushikana.
Tsvagiridzo inoratidza kuti OEA inobatsira kumisikidza PPAR receptors muamygdala, chikamu chehuropi chine mutoro wekudzora kusagadzikana uye kusagadzikana. Iyi activation inotungamira mukuderedzwa kushushikana uye nhanho dzekushushikana. Inobatsira kuderedza kuzvidya mwoyo uye inosimudzira pfungwa yekugara zvakanaka.
Pamusoro pezvo, OEA yakabatanidzwa nekudzorwa kwemazinga e dopamine muuropi, ayo anogona kuita basa mukugadzirisa mafungiro uye hutano hwepfungwa hwakazara.
Kuzvimba uye immune function
Kuzvimba kusingaperi kwakabatana neakasiyana matambudziko ehutano, anosanganisira kufutisa, chirwere cheshuga uye chirwere chemoyo. Oleoylethanolamide (OEA) yakaratidzwa kubatsira kubatsira kuderedza kuzvimba mumuviri.
Tsvagiridzo inoratidza kuti OEA inobatsira kudzikisa kugadzirwa kwema cytokines, ari mamaki ekuzvimba mumuviri. OEA inobatsirawo kuderedza oxidative kusagadzikana, chikonzero chikuru chekuzvimba mumuviri.
Oleoylethanolamide (OEA) inoratidza vimbiso mukugadzirisa mhinduro dzekuzvimba mumuviri, izvo zvingave zvine chekuita nekushanda kwese immune nekudzivirira chirwere. Oleoylethanolamide (OEA) poda inogona kupa hutano hurefu kwenguva refu nekutsigira mhinduro ine hutano inoputika.
Lower ropa lipids uye kuramba atherosclerosis
Peroxisome proliferator-activated receptor-α (PPAR-α) imhando yekugamuchira inowirirana zvakanyanya nemabasa ekugadzirisa muviri. PPAR-α inotora chikamu mu lipid metabolism nekusunga kune peroxisome proliferator mhinduro chinhu. Kutakurwa kwemetabolic, immune regulation, anti-inflammation, anti-proliferation uye mamwe maitiro ane hukama anowedzera kuita basa mukugadzirisa ropa lipids uye anti-atherosclerosis.
Oleoylethanolamide (OEA) inonzi endocannabinoid analog iyo inogadzirwa kana matishu emuviri amutswa. Zvidzidzo zvakaratidza kuti OEA inoshandisa PPAR-M, inoderedza kusunungurwa kwe endothelin-1, inhibits vasoconstriction uye smooth muscle cell proliferation, inosimudzira vasodilation, uye panguva imwechete inowedzera synthesis ye endothelial nitric oxide synthase uye inokonzera kugadzirwa kwenitric oxide yakawanda. synthase. nitrogen, nekudaro ichidzikisa kugadzirwa kwevascular cell adhesion molecules, kuwana anti-inflammatory effects, uye kuita mhedzisiro yekudzikisa ropa lipids uye anti-atherosclerosis.
Utano hwehuropi uye basa rekuziva
Tsvagiridzo inoratidza OEA poda inogona zvakare kuve nemhedzisiro pahutano hwehuropi uye kugona kwekuziva. Oleoylethanolamide (OEA) yakaratidzwa kuyambuka ropa-brain barriers uye inodyidzana nema receptors muuropi, zvichikonzera zvinogona kuitika pakuziva basa uye neuroprotection.
Zvakakodzera kutaura kuti OEA inogona kukanganisa kufambira mberi kweAD. Iyo amyloid-beta (Aβ) pathology yeAlzheimer's disease (AD) inoperekedzwa nekuchinja kukuru mumasero eglial muuropi. Genome-wide association zvidzidzo zvakaratidza kuti microglia uye nzira dzadzo dzine hukama, dzakadai se phagocytosis, lipid metabolism, uye mhinduro yekudzivirira zvirwere, inoita basa rinokosha mune etiology yekunonoka-kutanga AD.
Oleylethanolamine (OEA) ndeyekushanduka-shanduka kwakachengetedzwa endogenous lipid molecule iyo yakaratidzwa kuwedzera hupenyu uye hutano muC. elegans. Mumhuka dzinoyamwisa, OEA inogadzirwa mumativi emukati uye nechepakati tsinga system, uye chidzidzo chelipidomics chakaratidza kuti OEA nemamwe mafuta acids ethanolamine akaderedzwa zvakanyanya mucerebrospinal fluid uye plasma yevarwere veAD, zvichireva kuti mamorekuru akadai seOEA anogona kukanganisa kufambira mberi kweAD. .
1. Ziva kwakabva uye kuchena
Paunenge uchitenga Oleoylethanolamide (OEA) poda, unofanirwa kufunga nezvekwakabva uye kuchena kwechigadzirwa. Tsvaga vatengesi vane mukurumbira vanoshandisa zvigadzirwa zvemhando yepamusoro uye vanotevedzera zvakaomesesa zvekugadzira zviyero. Nenzira yakanaka, OEA poda inofanira kutorwa kubva kune zvakasikwa uye nekuchena kwepamusoro kuti ive nechokwadi chekushanda kwayo nekuchengeteka.
2. Tarisa kuongororwa kwevatatu
Kuve nechokwadi chehutano uye kuchena kweOleoylethanolamide (OEA) powder, zvakakosha kusarudza zvigadzirwa zvakaedzwa nevechitatu-party laboratories. Chechitatu-bato kuyedzwa kunoita kuti OEA hupfu haina tsvina uye inosangana neyakatsanangurwa potency uye kuchena mazinga. Tsvaga zvigadzirwa zvinopa zviripachena uye zvinogoneka bvunzo mhinduro, zvinokupa runyararo rwepfungwa nezve mhando yeOEA poda yaunotenga.
3. Funga nezvekubika
Oleoylethanolamide (OEA) poda inowanikwa mumhando dzakasiyana-siyana, kusanganisira capsules uye powders. Paunenge uchisarudza formula yakakunakira, funga zvaunofarira uye mararamiro. Capsules inopa yakaringana uye chaiyo dosing, nepo hupfu uye zvinwiwa zvinogona kusanganiswa zviri nyore muzvinwiwa kana chikafu.
4. Ongorora mukurumbira wemupi
Paunenge uchitenga OEA poda, zvakakosha kutenga kubva kune ane mukurumbira uye akavimbika mutengesi. Tsvakurudza mukurumbira wemutengesi, ongororo dzevatengi, uye zvitupa kuti uve nechokwadi chekuti uri kuwana chakavimbika uye chemhando yepamusoro chigadzirwa. Mutengesi ane mukurumbira achave pachena nezvekutsvaga kwavo, maitiro ekugadzira, uye mhando yechigadzirwa, zvichikupa chivimbo mukutenga kwako.
5. Ongorora mutengo uye kukosha
Nepo mutengo usingafanire kunge uri iwo wega sarudzo, zvakakosha kuti utarise kukosha kweOEA poda yauri kutenga. Enzanisa mitengo kubva kune vakasiyana vatengesi, uchifunga nezvekwakabva chigadzirwa, kuchena, kuumbwa uye mukurumbira. Ramba uchifunga kuti yakakwirira-yepamusoro yeOEA powder inogona kunge yakadhura, asi kukosha kwainopa maererano nekubudirira uye kuchengeteka kunokosha mari.
6. Bvunza nyanzvi yezveutano
Usati wawedzera OEA poda kune yako yekuwedzera regimen, zvinokurudzirwa kubvunza nyanzvi yezvehutano, kunyanya kana uine chero mamiriro ehutano ari pasi pehutano kana uri kutora mishonga. Nyanzvi yehutano inogona kupa nhungamiro yakasarudzika uye kuona OEA yakakodzera hutano hwako hwezuva nezuva.
Kwapera mazuva apo iwe waisaziva kwekutenga Oleoylethanolamide (OEA). Kubhowekana kwainge kwaita kare. Iwe unofanirwa kubva kuchitoro kuenda kuchitoro, kuzvitoro zvikuru, mall, uye kubvunza nezve zvaunofarira zvekuwedzera. Chinhu chakaipisisa chinogona kuitika kufamba-famba zuva rose uye kwete kuguma wawana zvaunoda. Zvakatoipa, kana ukawana chigadzirwa ichi, unozonzwa uchimanikidzwa kutenga icho chigadzirwa.
Nhasi, kune nzvimbo dzakawanda dzekutenga Oleoylethanolamide (OEA)hupfu. Nekuda kweinternet, unogona kutenga chero chinhu pasina kana kusiya imba yako. Kuve online hakungoite kuti basa rako rive nyore, zvakare kunoita kuti ruzivo rwako rwekutenga ruve nyore. Iwe zvakare une mukana wekuverenga zvakawanda nezve ichi chinoshamisa chekuwedzera usati wafunga kuzvitenga.
Kune vakawanda vatengesi vepamhepo nhasi uye zvingave zvakaoma kwauri kuti usarudze yakanakisa. Chaunofanirwa kuziva ndechekuti kunyangwe vese vachivimbisa goridhe, havasi vese vanonunura.
Kana iwe uchida kutenga Oleoylethanolamide (OEA) poda yakawanda, unogona kugara uchivimba nesu. Isu tinopa zvakanakisa zvekuwedzera izvo zvinounza mhedzisiro. Order kubva kuSuzhou Myland Pharm nhasi uye tanga rwendo rwako kune hutano hwakanaka.
Suzhou Myland Pharm & Nutrition Inc. yave ichiita bhizinesi rekuwedzera chikafu kubva muna 1992. Ndiyo kambani yekutanga muChina kugadzira nekutengesa mhodzi dzemazambiringa.
Iine makore makumi matatu echiitiko uye ichitungamirwa nehunyanzvi hwepamusoro uye yakagadziridzwa zvakanyanya R&D zano, kambani yakagadzira mhando yezvigadzirwa zvemakwikwi uye ikava yekuvandudza hupenyu hwesainzi yekuwedzera, yetsika synthesis uye kambani yekugadzira masevhisi.
Pamusoro pezvo, Suzhou Myland Pharm & Nutrition Inc. zvakare iri FDA-yakanyoreswa mugadziri. Zviwanikwa zvekambani zveR&D, zvivakwa zvekugadzira, uye zviridzwa zvekuongorora ndezvazvino uye zvinoshanda uye zvinogona kugadzira makemikari kubva kumamirigiramu kusvika kumatani muchiyero, uye zvinoenderana neISO 9001 zviyero uye magadzirirwo ekugadzira GMP.
Mubvunzo: Chii chinonzi Oleoylethanolamide (OEA) poda uye inoshanda sei?
A: Oleoylethanolamide (OEA) poda ndeye yakasikwa lipid molecule inogadzirwa mudumbu diki. Inoshanda nekuita peroxisome proliferator-activated receptor alpha (PPAR-α), iyo inobata basa mukugadzirisa metabolism uye kukurudzira manzwiro ekuzara.
Mubvunzo: Ndezvipi zvingave zvinobatsira zvekushandisa Oleoylethanolamide (OEA) powder?
A: Zvimwe zvingangobatsira zvekushandisa OEA poda zvinosanganisira kudzvinyirirwa kwechido, kudzora uremu, uye kutsigirwa kwemetabolism ine hutano. Inogonawo kuva ne-anti-inflammatory uye neuroprotective properties.
Mubvunzo: Ndinosarudza sei yepamusoro-soro yeOleoylethanolamide (OEA) powder?
A: Pakusarudza OEA poda, zvakakosha kutsvaga mutengesi anoyemurika anopa wechitatu-bato kuyedzwa kwekuchena uye potency. Uyezve, funga kunobva hupfu uye sarudza zvigadzirwa zvakatorwa kubva kune zvakasikwa, zvinogara zviripo.
Disclaimer: Ichi chinyorwa ndecheruzivo rwese chete uye hachifanirwe kutorwa sechero zano rekurapa. Imwe yeruzivo rweblog post runobva kuInternet uye haina hunyanzvi. Iyi webhusaiti inongova nebasa rekugadzirisa, kufomatidza uye kugadzirisa zvinyorwa. Chinangwa chekuendesa rumwe ruzivo hachirevi kuti unobvumirana nemaonero ayo kana kusimbisa uchokwadi hwezvirimo. Nguva dzose bvunza nyanzvi yezvehutano usati washandisa chero chekuwedzera kana kuita shanduko kuhutano hwako hwehutano.
Nguva yekutumira: Aug-23-2024
