Sezvatinokura, ndezvemuzvarirwo kuti isu titange kufunga nezvekuti tingagara sei tiine hutano uye tichishanda kwenguva yakareba sezvatinogona. Imwe sarudzo yakanaka ndeye urolithin A, iyo yakaratidzwa kushandura nzira inonzi mitophagy, iyo inobatsira kujekesa mitochondria yakakuvadzwa uye inosimudzira kusikwa kwemitochondria itsva, ine utano. Nekutsigira hutano hwemitochondrial, urolithin A inogona kubatsira kunonoka kuchembera padanho remasero. Tsvagiridzo inoratidzawo kuti urolithin A inogona kunge iine zvimwe zvakanaka, sekutsigira hutano hwetsandanyama uye kushanda uye inogona kutoderedza kuzvimba mumuviri.
Vanhu gut microbiomes vanosiyana. Zvinhu zvakadai sekudya, makore, uye genetics zvose zvinobatanidzwa uye zvinotungamirira kune misiyano mukugadzirwa kwemazinga akasiyana eurolithin A. Vanhu vasina mabhakitiriya mumatumbo avo havagoni kubudisa UA. Kunyange avo vanokwanisa kugadzira urolithin A havagoni kuita urolithin A yakakwana. Zvinogona kutaurwa kuti chikamu chimwe chete muzvitatu chevanhu vane urolithin A yakakwana.
Saka, ndeapi akanakisa masosi eurolithin A?
Damba: Pomegranate ndeimwe yezvakapfuma zvechisikigo zvitubu zveurolithin A.Chibereko ichi chine ellagitannins, iyo inoshandurwa kuita urolithin A neiyo intestinal microbiota. Kushandisa muto wemapomegranate kana mhodzi dzepomegranate dzinopa huwandu hukuru hweurolithin A, zvichiita kuti ive chikafu chakanakisa chemukomboni uyu.
Ellagic acid supplements: Ellagic acid supplements ndiyo imwe nzira yekuwana urolithin A. Mushure mekushandisa, ellagic acid inoshandurwa kuva urolithin A ne intestinal microbiota. Izvi zvinowedzera zvinobatsira kune vanhu vasingawanzo kushandisa urolithin A-rich chikafu.
Zvibereko: Mamwe mabheri, akadai seraspberries, mastrawberries, uye mablackberries, ane ellagic acid, inogona kubatsira mukugadzirwa kweurolithin A mumuviri. Kusanganisira akasiyana ma berries mukudya kunogona kubatsira kuwedzera ellagic acid kudya uye inogona kuwedzera urolithin A mazinga.
Zvokudya zvinovaka muviri: Zvimwe zvinovaka muviri zvinogadzirwa zvakagadzirirwa kupa urolithin A zvakananga. Izvi zvinowedzera zvinowanzove nemafuta echisikigo akapfuma muurolithin A, achipa yakanyanyisa uye yakanakira nzira yekuwedzera yako urolithin A kutora.
Gut Microbiota: Kuumbwa kwegut microbiota kunoita basa rakakosha mukugadzirwa kweurolithin A. Mamwe marudzi emabhakitiriya ari muura ane basa rekushandura ellagitannins uye ellagic acid kuita urolithin A. Kutsigira hutano uye hwakasiyana gut microbiota kuburikidza neprobiotics, prebiotics. , uye fiber yezvokudya inogona kuwedzera urolithin A kugadzirwa mumuviri.
Checherechedzo, iyo bioavailability uye efficacy yeurolithin A inogona kusiyana zvichienderana nekwakabva uye munhu mumwe chete zvinhu. Nepo zviwanikwa zvakaita semapomegraneti nemabheri zvinopa humwe hutano hunovaka muviri, zvinovaka muviri zvinogona kupa yakavimbika, yakanyanya kuwanda yeurolithin A.
Sezvo isu tichikura, miviri yedu inobereka zvishoma urolithin, izvo zvakakonzera kugadzirwa kweurolithin yekuwedzera senzira inogona kutsigira hutano hweserura uye kuchembera.
Imwe yemabhenefiti makuru eurolithin kugona kwayo kusimudzira mitochondrial basa, iyo yakakosha pakugadzirwa kwesimba uye hutano hwesero. Mitochondria ndiwo masimba emasero edu, madiki organelles anoshandura glucose uye oxygen kuita adenosine triphosphate (ATP) yesimba. Sezvatinokura, basa ravo rinogona kuderera, zvichiita kuti kuve nezvinetso zvakasiyana-siyana zvehutano. Urolithins yakaratidzwa kubatsira kuvandudza mitochondrial basa, inogona kuwedzera mazinga esimba uye simba rose.
Kune vanhu vane hunyanzvi hwemuviri hwakadzikira, urolithin A inogona kushandiswa kusimudzira hutano hwemitochondrial pasina kudiwa kwekurovedza muviri. Urolithin A, iyo inogona kuwanikwa kubva pakudya kana, zvinobudirira, kuburikidza nekuwedzera kwezvokudya, yakaratidzwa kukurudzira hutano hwemitochondrial uye kutsungirira kwemisumbu. Inoita izvi nekuvandudza mitochondrial chiitiko, kunyanya nekuita iyo mitophagy process.
Pamusoro pemhedzisiro yayo pamitochondrial basa, urolithin yakadzidzwa kune yavo inogona anti-kuzvimba uye antioxidant zvinhu. Kusagadzikana kuzvimba uye oxidative kusagadzikana ndizvo zviri pasi pezvirwere zvakawanda zvisingaperi, saka kugona kweurolithin kurwisa nyaya idzi kunogona kuve nemabhenefiti akanyanya kuhutano hwese. Zvimwe zvidzidzo zvakare zvinoratidza kuti urolithin inogona kuve nemhedzisiro yakanaka pahutano hwetsandanyama uye kuita kwemuviri, zvichiita kuti ive sarudzo inokwezva yevamhanyi nevanofarira zvekusimba.
Urolithin Amusanganiswa wechisikigo unobva ku ellagic acid, inowanikwa mune mimwe michero nenzungu. Izvo zvakaratidzwa kumisa maitiro anonzi mitophagy, nzira yemuviri yepanyama yekubvisa yakakuvadzwa mitochondria uye kukurudzira hutano hwesero kushanda. Iyi nzira yakakosha pakuchengetedza hutano hwese cellular uye yakabatanidzwa nehupenyu hurefu uye njodzi yakaderedzwa yezvirwere zvine chekuita nezera.
NMN, kune rumwe rutivi, ndiyo inotangira NAD + (nicotinamide adenine dinucleotide), coenzyme inoita basa rakakosha mumasero metabolism uye kugadzirwa kwesimba. Sezvo isu tichikura, mazinga eNAD + anodzikira, zvichikonzera kudzikiswa kwesero kushanda uye kuwedzera njodzi yezvirwere zvine chekuita nezera. Nekuwedzera neNMN, tinotenda kuti tinogona kuwedzera NAD+ mazinga uye kutsigira hutano hwesero uye hupenyu hurefu.
Saka ndeipi iri nani? Chokwadi ndechekuti, haisi mhinduro iri nyore. Ose ari maviri urolithin A neNMN vakaratidza mhedzisiro inovimbisa muzvidzidzo zvepreclinical uye vese vane nzira dzakasiyana dzekuita. Urolithin A inomisa mitophagy, nepo NMN inowedzera NAD + mazinga. Zvinogoneka chose kuti aya makomisheni maviri anopindirana uye anopa mabhenefiti akakura kana asanganiswa.
Kuenzanisa kwakananga kwemusoro-kune-musoro kweurolithin A neNMN hakuna kuitwa muzvidzidzo zvevanhu, saka zvakaoma kunyatsotaura kuti ndeipi iri nani. Zvisinei, zvose zviri zviviri zvakaratidzwa kuti zvine simba rekusimudzira kukwegura kwakanaka uye zvinogona kuva nemigumisiro ye synergistic kana yakashandiswa pamwe chete.
Zvakakoshawo kufunga misiyano yemunhu mumwe nemumwe uye kuti munhu wega wega angapindura sei zvakasiyana kumakomponi aya. Vamwe vanhu vanogona kunge vaine mhinduro yakanyatsojeka kune urolithin A, nepo vamwe vanogona kubatsirwa zvakanyanya kubva kuNMN. Genetics, mararamiro, uye zvimwe zvinhu zvinogona kukanganisa mapinduriro anoita munhu ega kune aya makomponi, zvichiita kuti zviome kuita mhedziso yakafara pamusoro pekuti komisheni iri nani.
Pakupedzisira, mubvunzo wekuti urolithin A iri nani pane NMN haisi nyore kupindura. Ose makomboni akaratidza kugona kukurudzira kuchembera kune hutano uye ese ane nzira dzakasiyana dzekuita. Nzira yakanakisa inogona kunge iri yekufunga kutora ese ari maviri ekuwedzera panguva imwe chete kuti awedzere mabhenefiti avo.
1. Utano Hwetsandanyama: Chimwe chezvikomborero zvakakosha zveurolithin A kukwanisa kwayo kutsigira hutano hwemhasuru. Sezvo isu tichikura, miviri yedu inongoona kuderera kwemhasuru uye simba. Nekudaro, tsvagiridzo inoratidza kuti urolithin A inogona kubatsira kurwisa maitiro aya nekusimudzira basa remitochondria, dzimba dzemagetsi dzesero. Nekuita izvi, zvinogona kubatsira kuvandudza kushanda kwemhasuru uye kukurudzira kushanda kwemuviri kwese.
2. Kurarama kwenguva refu: Chimwe chikonzero chinomanikidzira chekufunga nezveurolithin A supplementation ndiyo inokwanisa kukurudzira hupenyu hurefu. Tsvagiridzo inoratidza kuti komisheni iyi inogona kumisa maitiro anonzi mitophagy, ayo ane basa rekubvisa yakakuvadzwa mitochondria. Nekubvisa izvi zvisingashande zvinhu, Urolithin A inogona kubatsira kuwedzera hupenyu uye kutsigira hupenyu hwese hune hutano.
3. Cellular Health: Urolithin A yakaratidzawo kutsigira hutano hwesero uye basa. Nekuvandudza mitochondrial basa uye nekusimudzira mitophagy, komisheni iyi inogona kubatsira kusimudzira hutano hwese uye kupora kwemasero. Izvi, zvakare, zvinogona kuva nemigumisiro yakanaka pane zvose zvehutano, kubva pakugadzirwa kwesimba kusvika kumabasa ekudzivirira zvirwere.
4. Anti-Inflammatory Properties: Chirwere chisingaperi chinowanzoitika mumamiriro ezvinhu akawanda ehutano, uye Urolithin A yakaratidzwa kuva nehutachiona hwehutachiona hunogona kubatsira kuderedza njodzi yezvimwe zvirwere uye kutsigira hutano hwakakwana uye hutano.
5. Utano hwehuropi: Tsvakurudzo iri kubuda inoratidza kuti urolithin A inogonawo kuva nemigumisiro yehutano hwehuropi. Nekutsigira mitochondrial basa uye nekusimudzira hutano hweserura, komisheni iyi inogona kubatsira kudzivirira kuderera kwekuziva kwakabatana nezera uye neurodegenerative zvirwere.
Chokutanga uye chakakosha, zvakakosha kunzwisisa kuti kwete zvoseurolithin A inowedzeravakasikwa vakaenzana. Hunhu uye kuchena kweUrolithin A inogona kusiyanisa zvakanyanya pakati pezvigadzirwa zvakasiyana, saka zvakakosha kuti uite tsvakiridzo yako uye usarudze wekuwedzera kubva kumugadziri ane mukurumbira. Tarisa ma supplements ari wechitatu-bato akaedzwa kuchena uye potency kuona kuti uri kuwana chemhando yepamusoro chigadzirwa.
Pamusoro pemhando yeurolithin A inotorwa, zvakakoshawo kufunga nezvechimiro chekuwedzera. Urolithin A inowanikwa mumhando dzakasiyana siyana, kusanganisira capsules, hupfu, uye mvura. Funga zvaunofarira pachezvako uye mararamiro paunenge uchisarudza iyo fomati inonyanya kuenderana nekuisa muhupenyu hwako hwezuva nezuva.
Chimwe chinhu chekufunga nezvacho pakusarudza urolithin A yekuwedzera ndeye dosage. Mishonga yakasiyana-siyana inogona kunge iine huwandu hwakasiyana hweurolithin A pakushanda, saka zvakakosha kuti utarise zvaunoda iwe pachako uye zvinangwa paunenge uchisarudza dosi rakakunakira. Kana usina chokwadi nezve dosi yakakunakira, bvunza nyanzvi yezvehutano kuti uwane hutungamiriri hwemunhu.
Pamusoro pezvo, funga kana paine zvimwe zvinongedzo zviripo muurolithin A yekuwedzera. Zvimwe zvigadziriso zvinogona kunge zvine zvinhu zvakawedzerwa, zvakadai se antioxidants kana mamwe maitiro e-bioactive, izvo zvinogona kuwedzera migumisiro yeurolithin A. Zvisinei, zvakakosha kuve nechokwadi kuti chero zvimwe zvigadzirwa zvakachengeteka uye zvinobatsira kune zvaunoda zvehutano.
Pamusoro pezvo, pakusarudza urolithin A yekuwedzera, ndapota funga nezvehutano hwako uye chero mamiriro ezvehutano aripo. Kana uine hutano huri pasi pemamiriro ezvinhu kana uri kutora mishonga, zvakakosha kutarisa nemupi wako wehutano usati watanga chero chirongwa chekuwedzera chekuwedzera kuti uone kuti yakachengeteka uye yakakodzera iwe.
Chekupedzisira, zvakakosha kudzora zvaunotarisira kana uchitora urolithin A yekuwedzera. Nepo urolithin A inoratidza chivimbiso chikuru mukuvandudza tsandanyama basa, mazinga esimba, uye hutano hwesero hwese, mhedzisiro yega yega inogona kusiyana. Zvakakosha kupa wedzero nguva yakakwana yekushanda uye kuenderana nekushandisa kwako kuona mibairo yakanaka.
Suzhou Myland Pharm & Nutrition Inc. yave ichiita bhizinesi rekuwedzera chikafu kubva muna 1992. Ndiyo kambani yekutanga muChina kugadzira nekutengesa mhodzi dzemazambiringa.
Iine makore makumi matatu echiitiko uye ichitungamirwa nehunyanzvi hwepamusoro uye yakagadziridzwa zvakanyanya R&D zano, kambani yakagadzira mhando yezvigadzirwa zvemakwikwi uye ikava yekuvandudza hupenyu hwesainzi yekuwedzera, yetsika synthesis uye kambani yekugadzira masevhisi.
Pamusoro pezvo, kambani iyi zvakare FDA-yakanyoreswa mugadziri, inovimbisa hutano hwevanhu nemhando yakagadzikana uye kukura kwakasimba. Zviwanikwa zvekambani zveR&D uye zvivakwa zvekugadzira uye zviridzwa zvekuongorora ndezvemazuva ano uye zvinoshanda, uye zvinokwanisa kugadzira makemikari pamilligram kusvika toni sikero zvichiteerana neISO 9001 zviyero uye GMP maitiro ekugadzira.
Mubvunzo: Chii chinonzi urolithin A?
A: Urolithin A inhengo yechisikigo inogadzirwa mumuviri mushure mekushandiswa kwezvimwe zvekudya, zvakaita semapomegranati uye michero. Inowanikwawo sekuwedzera.
Mubvunzo: Urolithin A inoshanda sei?
A: Urolithin A inoshanda nekuita cellular process inonzi mitophagy, iyo inobatsira kubvisa yakakuvadzwa mitochondria kubva kumaseru. Izvi, zvakare, zvinobatsira kuvandudza cellular function uye hutano hwese.
Mubvunzo: Ndezvipi zvingave zvinobatsira zveurolithin A supplementation?
A: Zvimwe zvingangobatsira zveurolithin A supplementation zvinosanganisira kuvandudzwa kwemhasuru basa, kuwedzera simba rekugadzira, uye kuwedzera hupenyu hurefu. Zvinogona kubatsirawo kutsigira hutano hwese uye kugara zvakanaka sezvatinokura.
Disclaimer: Ichi chinyorwa ndecheruzivo rwese chete uye hachifanirwe kutorwa sechero zano rekurapa. Imwe yeruzivo rweblog post runobva kuInternet uye haina hunyanzvi. Iyi webhusaiti inongova nebasa rekugadzirisa, kufomatidza uye kugadzirisa zvinyorwa. Chinangwa chekuendesa rumwe ruzivo hachirevi kuti unobvumirana nemaonero ayo kana kusimbisa uchokwadi hwezvirimo. Nguva dzose bvunza nyanzvi yezvehutano usati washandisa chero chekuwedzera kana kuita shanduko kuhutano hwako hwehutano.
Nguva yekutumira: Mar-06-2024
