Trigonelline is alkaloid inowanzoitika inowanikwa mumiti yakadai sefenugreek nekofi. Trigonelline HCl, iyo hydrochloride fomu ye trigonelline, ikomisheni inonakidza inoita basa mukutsigira kudzora shuga yeropa, lipid inogona kuita basa remetabolism uye yekuziva basa. Sezvo tsvakiridzo ichienderera mberi nezvekomboni iyi, zvakakosha kuti tigare tichiziva nezvezvichangobva kuitika. Kunyangwe iwe uchifarira mushonga wenaturopathic, kuvandudzwa kwemishonga, kana kungoda kuwedzera ruzivo rwako, trigonelline HCL zvirokwazvo inyaya yekutariswa muna 2024.
Zita resainzi re trigonelline ndi trimethylxanthine. Iyo ine nitrogen-ine alkaline komboni uye ndeye pyridine alkaloids. Trigonelline inonyanya kutorwa kubva kune leguminous chirimwa fenugreek. Fenugreek chirimwa chine leguminous. Icho chirimwa chegore negore chinomera kuWest Africa uye chave kuparadzirwa zvakanyanya muAfrica, Europe, Asia nedzimwe nzvimbo. Mukuwedzera, inowanikwawo mubhinzi dzekofi, alfalfa, mulberry mashizha, radish, soya uye zvimwe zvinomera, pamwe chete nemolluscs, hove dzegungwa uye mumhuka dzinoyamwisa. Coffee bhinzi ndiyo inonyanya kukonzera trigonelline mushure mefenugreek. Parizvino, kune nzira dzakawanda dzekuyera trigonelline mubhinzi dzekofi, kusanganisira yakakwira-performance liquid chromatography, spectrophotometry, nezvimwe.
Trigonelline chinhu chinotangira chinoburitsa flavour panguva yekugocha kofi. Ndiyo imwe yemanyuko ekuvava mukofi. Icho zvakare chikamu chepamberi chemafuta akawanda anonhuhwirira. Mazuva ano, inogona kuve nyowani nyowani yekugadzira anti-kuchembera inoshanda chikafu.
Trigonelline ine mabasa akasiyana-siyana ehupenyu, kusanganisira antioxidant, kuderedza shuga yeropa, kutsvaira mahara radicals, kuvandudza mitochondrial basa, kuwedzera simba remhasuru, kuderedza kukuvadzwa kwesero, kuvandudza kushanda kwekuziva, etc. Kubva pane izvi, trigonelline inoshandiswa zvakanyanya mumishonga, cosmetics. uye kudya. Zvekuwedzera, zvigadzirwa zvehutano nezvimwe minda zvakaratidza tarisiro yakanaka yekushandisa. Parizvino, trigonelline yakatengeswa, asi kune zvishoma zvigadzirwa zvekutengesa uye musika une nzvimbo yakafara yekusimudzira. Nekutsvagisa kwakadzama mune ramangwana, zvigadzirwa zvakawanda zvine trigonelline sechinhu chikuru chinogadzirwa mune ramangwana.
Inowanzo kunzi simba resero, mitochondria inoita basa rakakosha mukugadzira simba remabasa emasero. Trigonelline hydrochloride ialkaloid yechisikigo inowanikwa muzvirimwa zvakaita sefenugreek uye yakagamuchira kutariswa kwezvinogona kuitika pamitochondrial basa.
Mitochondria ine basa rekugadzira adenosine triphosphate (ATP), iyo huru sosi yesimba remaserura maitiro. Mitochondrial dysfunction inogona kutungamira kune akati wandei matambudziko ehutano, kusanganisira metabolic kusagadzikana, neurodegenerative zvirwere, uye zvirwere zvine chekuita nekuchembera. Naizvozvo, kunzwisisa izvo zvinopesvedzera basa remitochondrial kwakakosha zvikuru muminda ye cell biology uye mushonga.
Mitochondrial dysfunction uye yakaderedzwa NAD + mazinga anoita mabasa akakosha mukuita kwekurasikirwa kwemhasuru. Mitochondria inzvimbo dzekugadzira simba mukati memasero, ane basa rekugadzira iyo molecule yeATP inodiwa nemaseru. Kana basa remitochondrial rikakuvadzwa kana kusarongeka, zvinotungamira mukushayikwa kwesimba kumasero, zvichikanganisa basa rakajairwa uye metabolic process yemaseru emhasuru, nekudaro ichimhanyisa kuitika kwekurasikirwa kwemhasuru.
Pamusoro pezvo, NAD+ (nicotinamide adenine dinucleotide) yakakosha coenzyme mumasero, inobatanidzwa mukugadzirisa simba remetabolism uye redox maitiro mumasero. Sezvo isu tichikura, mwero weNAD + mumasero uchadzikira. Kuderera kwemazinga eNAD + kunogona kukanganisa intracellular redox chiyero, kuwedzera cellular oxidative kusagadzikana uye mhinduro dzekuzvimba, nekudaro zvichikanganisa basa uye kupona kwemaseru masero.
Mhedzisiro ye trigonelline pakuvandudza mitochondrial basa inoratidzwa zvakanyanya mune zvinotevera zvinhu:
1. Kuvandudza mitochondrial basa
Tsvagiridzo inoratidza kuti Trigonelline HCl inogona kudzora mitochondrial chiitiko nekukanganisa cheni yekutakura maelectron, nhevedzano yeprotein complexes inogadzira ATP. Nekuwedzera kushanda kweketani yekutakura erekitironi, trigonelline HCl inogona kusimudzira kugadzirwa kweATP, nekudaro ichitsigira cellular simba metabolism.
Uye zvakare, trigonelline inogona kuwedzera NAD + mazinga, uye NAD + yakakosha coenzyme ye oxidative phosphorylation mumitochondria. Nekuwedzera NAD + mazinga, trigonelline inogona kumisa iyo mitochondrial yekufema cheni uye kukurudzira ATP synthesis, nekudaro ichiwedzera mitochondrial chiitiko. Izvi zvinobatsira maseru kuchengetedza simba rakakwana mukupindura kushushikana kwekunze uye kuchengetedza zvakajairika sero basa.
2. Chengetedza mitochondria kubva mukukuvadza
Trigonelline ine antioxidant uye anti-kuzvimba mhedzisiro, inogona kubvisa mahara radicals uye kuzvimba zvinhu mumasero, uye kuderedza oxidative kusagadzikana uye kukuvara kwekuzvimba kune mitochondria. Panguva imwecheteyo, trigonelline inogona zvakare kudzikamisa iyo mitochondrial membrane chimiro, kudzivirira kudzikiswa kweiyo mitochondrial membrane kugona uye kuvhurwa kwemitochondrial permeability transition pores, nekudaro ichidzivirira mitochondria kubva mukukuvadzwa.
3. Kurudzira mitochondrial biogenesis
Trigonelline inogona kumutsa kudzokororwa uye kunyorwa kweiyo mitochondrial DNA uye kukurudzira kuumbwa kwemapuroteni emitochondrial, nekudaro ichiwedzera huwandu uye mhando yemitochondria. Izvi zvinobatsira maseru nekukurumidza kuwedzera huwandu hwemitochondria uye kunatsiridza kugadzirwa kwesimba pakupindura kune yakawedzera simba zvinodiwa.
4. Kurudzira insulin kunzwa
Tsvagiridzo inoratidza kuti trigonelline hydrochloride inogona kukanganisa glucose metabolism uye insulin senitivity, izvo zvine hukama nekuita mitochondrial. Trigonelline HCl inogona kutsigira zvisina kunanga hutano hwemitochondrial uye yakazara cellular simba chiyero nekusimudzira kushandiswa kwakanaka kweglucose uye kusaina insulin.
Trigonelline, inozivikanwawo seN-methylnicotinic acid, ndeye alkaloid inowanzoitika inowanikwa mumhando dzakasiyana dzezvirimwa, kusanganisira fenugreek, bhinzi dzekofi, uye zvimwe zvinorimwa.
Trigonelline HCl,kune rumwe rutivi, ndiyo hydrochloride munyu fomu ye trigonelline. Izvi zvinoreva kuti trigonelline hydrochloride inobva kune trigonelline yakasanganiswa nehydrochloric acid kuita munyu. Iyi shanduko inoshandura chimiro chemakemikari ye trigonelline, zvichikonzera kusiyana kwezvivakwa zvayo uye zvinogona kushandiswa.
Imwe yemisiyano mikuru pakati pe trigonelline ne trigonelline hydrochloride ndiko kunyungudika kwavo. Trigonelline inonyungudika zvishoma mumvura, nepo trigonelline hydrochloride ichinyungudika mumvura. Kuwedzera kunyungudika kwe trigonelline hydrochloride kunoita kuti ive yakakodzera kune mamwe maapplication, senge kugadzirwa kwezvekudya zvekuwedzera kana mishonga inoda kunyungudika kwemvura.
Panyaya yezvinogona kubatsira pahutano, trigonelline uye trigonelline HCl zvakadzidzwa nekuda kwemhedzisiro yadzo pane dzakasiyana siyana dzehutano. Trigonelline yakadzidzwa nekuda kwechinzvimbo chayo chinogona kutsigira kudzora shuga yeropa, lipid metabolism, uye cognitive basa. Imwe tsvagiridzo inoratidzawo kuti trigonelline inogona kunge iine antioxidant uye anti-kuzvimba zvivakwa, izvo zvinogona kubatsira kune yayo inogona kusimudzira hutano.
Saizvozvo, iyo yakawedzera solubility ye trigonelline hydrochloride inogona kuita kuti iwande bioavailable uye nyore kunyudzwa nemuviri, zvichigona kuwedzera kushanda kwayo mune mamwe maapplication. Izvi zvinonyanya kukosha mukugadzirwa kwezvokudya zvinowedzera kana mishonga yemishonga, apo trigonelline bioavailability ndiyo inokosha yekufungisisa.
Munyika yekuwedzera yezvekudya, trigonelline uye trigonelline HCl inogona kuverengerwa sezvimiro mumigadziriso yakanangana nerutsigiro rwemetabolism, basa rekuziva, kana zvimwe zvinangwa zvine chekuita nehutano. Sarudzo yekushandisa trigonelline kana trigonelline HCl mune yekuwedzera inogona kuenderana nezvinhu zvakaita seyaunoda dosage fomu, solubility zvinodiwa, uye chaiwo mabhenefiti ehutano akanangana.
Trigonelline HCl ndiyo hydrochloride munyu fomu ye trigonelline. Izvi zvinoreva kuti trigonelline hydrochloride inobva kune trigonelline yakasanganiswa nehydrochloric acid kuita munyu.
Panyaya yehutano hwayo mabhenefiti, iyo yakawedzera solubility ye trigonelline hydrochloride inogona kuita kuti iwande bioavailable uye nyore kunyudzwa nemuviri, zvichigona kuwedzera kushanda kwayo mune mamwe maapplication.
1. Anti-kuchembera
Musoro wekuchembera unogara uchitenderera pamorekuru akakosha — NAD+, nicotinamide adenine dinucleotide. Iyi yakakosha intracellular coenzyme inoita basa repakati mukugadzirisa simba metabolism uye redox maitiro. Iyo ine mukurumbira we "youth factor" uye "mupfumi nguva yebhangi".
NAD + ndiyo yakakosha cofactor yemasero simba metabolism. Sezvo isu tichikura, NAD + mazinga mumasero anodzikira.
Imwe tsvakiridzo yapfuura yakaratidza kuti kuyedza kuwedzera NAD + mazinga anogona kushandiswa senzira yekudzikisa kuchembera. Kune zvinhu zvakawanda mukudya zvinobatsira kuwedzera NAD +, senge NR (nicotinamide ribose), Trp (tryptophan) uye Nam (nicotinamide), pamwe nevhitamini B3 (inonziwo niacin), inoita seNAD + Precursor mamorekuru anogona kugadzira NAD + mushure mekupinzwa mumuviri.
Tsvagiridzo yazvino inoratidza kuti trigonelline iri zvakare NAD + precursor molecule. Trigonelline inogona kuwedzera NAD+ mazinga ne50% zvichienzaniswa neNMN, izvo zvinogona kuwedzera NAD+ mazinga nekaviri. Nekudaro, trigonelline inogona kuramba ichichengetedza yakakwira muserum 72 maawa mushure mekuwedzera, nepo NMN inonyangarika nekukurumidza mushure mekushandurwa kuita NAM.
Supplementing Trigonelline HCl inogona kuwedzera NAD + mazinga, kuwedzera mitochondrial chiitiko, uye kubatsira kuvandudza kuchembera.
2. Wedzera mazinga eNAD+ uye kunatsiridza tsandanyama atrophy
Sarcopenia, inozivikanwawo se sarcopenia, chirwere chekuderedzwa kwemhasuru huturu uye kuwanda, kazhinji inosanganiswa nekuchembera uye inoratidzwa nekuderera kweskeletal tsandanyama misa uye simba rayo. Kuratidzwa kwaro kwekliniki kunonyanya kusanganisira kuora muviri, kurasikirwa kwesimba remusimba, kuderedza simba rekubata, kufamba kusina kushanduka, nezvimwewo. Muzviitiko zvakakomba, zvinetso zvakadai sekuoma kumira, kudonha nyore, kuputsika, uye kusagadzikana kwemotokari kunogona kuitika.
Kuderera kweskeletal tsandanyama uye kusimba kwebhonzo kunowedzera njodzi yekutyoka mushure mekudonha, nepo tsandanyama atrophy inogona kukonzera kusagadzikana kwemotokari kushanda uye kukanganisa hupenyu hwese uye basa remurwere. Sezvo makore anowedzera, mushure memakore makumi matatu, mhasuru inoderera pamwero we3% kusvika 8% pagore; mushure memakore makumi matanhatu neshanu, chiyero chetsandanyama attenuation chinowedzera kukurumidza kusvika 6% kusvika 15%. Vamwe vanhu vanogona kutotambura ne sarcopenia, iyo inokonzera kuderera kwesimba remhasuru uye basa, zvichikanganisa kufamba. Muzviitiko zvakakomba, zvinogona kukonzera kurasikirwa kwekuzvimirira kwemuviri uye kuremara.
Kune zviitiko zviviri zvakakosha pakuitika kwe sarcopenia: imwe ndeye mitochondrial dysfunction mumasero, iyo inogona kungonzwisiswa seyakakwana kugadzirwa kwefekitari inotarisira kubudisa simba mumasero emasumbu; imwe yacho nicotinamide adenine dinucleus mumaseru Kuderera kwemazinga ecoenzyme molecule NAD+, iyo inoita basa rakakosha musimba remetabolism uye zvakananga uye zvisina kunanga mabasa mazhinji emasero.
Trigonelline mazinga akadzikira muvarwere vane sarcopenia, uye sezvo kurasikirwa kwemhasuru kuchiitika, serum trigonelline mazinga anowedzera kuderera. Trigonelline inonyatso wiriraniswa nesimba remhasuru uye mitochondrial simba rekugadzira muskeletal tsandanyama, uye serum mazinga e trigonelline anowiriranawo neNAD + mazinga muskeletal tsandanyama.
Tsvagiridzo inoratidza kuti trigonelline inogona kuwedzeredzwa kuburikidza nenzira nhatu: yekudya, microbial synthesis, uye metabolic nzira regulation.
1) Kudya kwekudya
Kudya chikafu chakapfuma mu trigonelline inzira yakananga yekuwedzera trigonelline mazinga mumuviri. Semuenzaniso, bhinzi dzekofi uye mhodzi dzefenugreek zvirimwa zvinozivikanwa kuve zvakapfuma mu trigonelline mune zvakasikwa. Zvisinei, kuvimba chete nekuwedzera kunwa kwekofi kuti uvandudze zvinetso zvehutano zvine chokuita nekukwegura zvingasava nyore sezvinofungidzirwa.
Pamusoro pezvo, inotangira trigonelline iniacin, saka mazinga etrigonelline mumuviri anogona kuwedzera zvisina kunanga nekudya chikafu chine niacin kana kuwedzera niacin.
2) Microbial synthesis
Vatsvakurudzi vakawana kuti kudya kwefiber kudya kwakabatana nemazinga e trigonelline mumuviri, zvichida nokuti trigonelline inogonawo kugadzirwa nematumbo flora metabolism. Naizvozvo, nekuwedzera kudya kwefiber, probiotics uye zvimwe zvinhu, tinogona kukwidziridza mudumbu hutachiona nharaunda uye kusimudzira kukura kwehutachiona hunogadzira trigonelline, nekudaro kuwedzera huwandu hwe trigonelline mumuviri. Asi zvakakosha kucherechedza kuti kune hukama hwakaoma pakati pekudya, gut microbiota uye hutano hwemhasuru hunoda kumwe kutsvagisa kujekesa.
3) Metabolic nzira yekudzora
NAPRT enzyme ndiyo yakakosha enzyme inoshandura trigonelline kuita NAD+ precursor. Naizvozvo, nekuwedzera kutaura kweNAPRT enzyme, kugona kwekushandura trigonelline kuita NAD + precursor inogona kuvandudzwa, nekudaro ichiwedzera mwero we trigonelline mumuviri. Pamusoro pezvo, zvidzidzo zvakaratidza kuti trigonelline ine hukama neS-adenosylmethionine-inotsamira methyltransferase. Nokudaro, nekuwedzera basa remhando iyi yemethyltransferase, kuumbwa kwe trigonelline mumuviri kunogona kukurudzirwa.
Serum kynurenine / vitamini B metabolome mazinga akadzidziswawo kune varwere vane sarcopenia uye kutonga kwakanaka. Hapana kuchinja kwakaonekwa mumatabolites akawanda panguva ye sarcopenia. Inosanganisira vhitamini B3 mafomu anogona kushanda seanogona NAD + precursors. Nekudaro, varwere ve sarcopenia vane yakaderera kutenderera kutenderera kwe trigonelline. Chidzidzo ichi zvakare chakawana kuti trigonelline inowedzera maseru NAD + mazinga.
3. Shuga yepasi uye lipids yeropa
Zvidzidzo zvakaratidza kuti mumhando ye2 chirwere cheshuga, trigonelline inogona kuderedza shuga yeropa uye insulin mazinga uye kuwedzera insulin senitivity index. Mukuwedzera, trigonelline yakawedzera pancreas uremu, pancreas-to-body weight ratio, uye insulin content, zvichiratidza kuti trigonelline inogona kuderedza mazinga eglucose muropa nekusimudzira pancreatic beta cell regeneration nekuvandudza insulin kuramba.
MuGK Type 2 diabetic rats, trigonelline yakaderedza serum uye hepatic triglyceride mazinga, yakaderera hepatic fatty acid synthase basa, uye yakawedzera hepatic carnitine palmitoyltransferase uye glucokinase mabasa.
Pamusoro pezvo, trigonelline HCL inogona kubatsira kudzora mazinga eshuga yeropa uye kuvandudza insulin senitivity. Izvi zvinogona kubatsira kune vanhu vane chirwere cheshuga kana avo vari panjodzi yekuva nechirwere cheshuga. Pamusoro pezvo, trigonelline HCL inogona kutsigira hutano hwecholesterol mazinga, ayo akakosha kune hutano hwemoyo
4. Antioxidant properties
Reactive okisijeni marudzi (ROS) ndiyo inonyanya kucherekedza yeoxidative kusagadzikana, iyo inogona kutungamirira kukukuvara kwesero uye kuitika kwezvirwere zvakasiyana. Zvidzidzo zvakawana kuti trigonelline haigone kuderedza zvakanyanya intracellular ROS mazinga, asiwo kuderedza pancreatic malondialdehyde uye nitric oxide mazinga. , wedzera superoxide dismutase, catalase, glutathione uye inducible nitric oxide synthase mabasa.
Izvi zvinoreva kuti inogona kubatsira kuchengetedza maseru kubva mukukuvadzwa kunokonzerwa neoxidative kusagadzikana uye mahara radicals. Antioxidants inoita basa rakakosha mukuchengetedza hutano hwese uye inogona kubatsira kuderedza njodzi yechirwere chisingaperi. Nekutsvaira mahara radicals, trigonelline HCL inogona kubatsira kune hutano hwese uye hupenyu hurefu.
5. Kuvandudza basa rekuziva
Zvidzidzo zvinoratidza kuti trigonelline inovandudza zvinyorwa zvekudzidza uye kuderera kwendangariro mukuchembera-yakawedzera mbeva pron 8 (SAMP8) modhi nekudzvinyirira pro-inflammatory cytokines uye kuwedzera neurotransmitter kuburitswa. Pamusoro pezvo, trigonelline inogona kukonzera kushanda kwe synaptic kukura mumunhu neuroblastoma SK-N-SH masero, ayo ane hukama nemaitiro ayo ekuita mukuvandudza ndangariro.
Kuchena uye kunaka
Kuchena uye kunaka kunofanirwa kunge kuri kutarisisa kwako pakusarudza trigonelline HCl yekuwedzera. Tarisa zvigadzirwa zvakaitwa muzvivakwa zvinoteedzera kuomarara kwemhando yekudzora zviyero uye zvine wechitatu-bato certification yekuchena uye potency. Pamusoro pezvo, funga kusarudza ma supplements ayo asina ekuwedzera ekuwedzera, mafirita, uye allergens kuti uve nechokwadi chekuti uri kuwana chemhando yepamusoro chigadzirwa.
Dosage uye kuisa pfungwa
The dosage uye confusion ye trigonelline HCl inogona kusiyana pakati pezvinowedzera. Zvaunoda chaizvo uye zvinangwa zvehutano zvinofanirwa kutariswa pakusarudza dosi yakakodzera yechigadzirwa. Semuenzaniso, kana iwe uchida kutsigira basa rekuziva, unogona kusarudza huwandu hwepamusoro hwe trigonelline HCL, nepo dhigirii yakaderera ingave yakakodzera rutsigiro rwehutano hwese. Gara uchibvunza nyanzvi yezvehutano kuti uone dosi chaiyo yezvido zvako wega.
Kujeka uye kuyedza
Sarudza trigonelline HCL yekuwedzera kubva kukambani ine mukurumbira inoisa pamberi pachena uye kwakaomarara kuyedzwa. Tarisa mhando dzinopa ruzivo rwakadzama nezve kutsvagisa, kugadzira, uye kuyedzwa kwezvigadzirwa zvavo. Yechitatu-bato kuyedzwa kuchena, potency, uye zvinosvibisa inova nechokwadi chekuwedzera kunaka uye kuchengetedzeka. Pamusoro pezvo, funga zvigadzirwa zvakadzidzwa nekiriniki kana kuve nerekodhi yezvakanaka zvevatengi ongororo uye kurudziro.
Synergistic ingredients
Mamwe matrigonelline HCl ekuwedzera anogona kunge aine zvimwe zvinongedzo zvinopindirana nemhedzisiro yawo uye inopa mamwe mabhenefiti. Semuenzaniso, unogona kuwana zvigadzirwa zvinosanganisa trigonelline HCl nemamwe makomisheni echisikigo anozivikanwa nerutsigiro rwavo rwekuziva kana metabolism-enhancing properties. Funga kana iwe uchida yakamira-yega trigonelline HCl yekuwedzera kana fomula ine synergistic zvinongedzo kugadzirisa akawanda maficha ehutano hwako uye kugara zvakanaka.
Kufunga nezveutano hwako
Pakusarudza trigonelline HCl yekuwedzera, zvakakosha kufunga chero hutano hwemunhu kana mamiriro ehutano aripo. Kana iwe uine chero mamiriro ehutano ari pasi pehutano kana uri kutora mishonga, bvunza nyanzvi yezvehutano usati wawedzera zvitsva zvekuwedzera kumaitiro ako ezuva nezuva. Vanogona kukupa hutungamiriri hwemunhu uye kukubatsira kuona kana trigonelline HCl yakakodzera pane zvaunoda iwe pachako.
Suzhou Myland Pharm & Nutrition Inc. yave ichiita bhizinesi rekuwedzera chikafu kubva muna 1992. Ndiyo kambani yekutanga muChina kugadzira nekutengesa mhodzi dzemazambiringa.
Iine makore makumi matatu echiitiko uye ichitungamirwa nehunyanzvi hwepamusoro uye yakagadziridzwa zvakanyanya R&D zano, kambani yakagadzira mhando yezvigadzirwa zvemakwikwi uye ikava yekuvandudza hupenyu hwesainzi yekuwedzera, yetsika synthesis uye kambani yekugadzira masevhisi.
Pamusoro pezvo, Suzhou Myland Pharm & Nutrition Inc. zvakare iri FDA-yakanyoreswa mugadziri. Zviwanikwa zvekambani zveR&D, zvivakwa zvekugadzira, uye zviridzwa zvekuongorora ndezvazvino uye zvinoshanda uye zvinogona kugadzira makemikari kubva kumamirigiramu kusvika kumatani muchiyero, uye zvinoenderana neISO 9001 zviyero uye magadzirirwo ekugadzira GMP.
Mubvunzo: Chii chinonzi trigonelline HCl inoshandiswa?
A: Trigonelline HCl inowanzoshandiswa sechikafu chekuwedzera kutsigira hutano hwese uye hutano. Iyo inozivikanwa nekugona kwayo kusimudzira hutano hwehuga hweropa uye kutsigira metabolic basa.
Mubvunzo: Trigonelline HCl inoshandiswa sei mune zvekudya zvinowedzera?
A: Trigonelline HCl inowanzobatanidzwa mune zvekudya zvinowedzera mumhando ye capsules, mapiritsi, kana poda. Inowanzo kusanganiswa nezvimwe zvinongedzo kugadzira maumbirwo anotsigira hutano hwemetabolism, mazinga esimba, uye hutano hwese.
Mubvunzo: Trigonelline HCl yakachengeteka kunwiwa here?
A: Trigonelline HCl inowanzoonekwa yakachengeteka,
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Nguva yekutumira: Aug-12-2024
