Kutanga, ngatitangei kunzwisisa kuti ketone esters chii. Ketone esters makemikari anobva mumitumbi yeketone, iyo inogadzirwa nechiropa panguva yekutsanya kana kuderera kwecarbohydrate. Aya makomisheni anogona kushandiswa seimwe imwe mafuta sosi yemuviri, kunyanya panguva dzekuwedzera kwesimba kudiwa, senge panguva yekurovedza muviri. Kana muviri uri mu ketosis, unoshandisa mafuta kuita simba zvakanyanya, nekudaro kuvandudza kutsungirira uye kuderedza kuvimba nezvitoro zveglycogen.
Kutanga, ngatiparadze izwi rekuti "ketone ester." Ketoni makemikari anogadzirwa nechiropa apo muviri uri mumamiriro e ketosis, iyo inoitika apo muviri unopisa mafuta panzvimbo yemakhahydrates ehuni. Ketone esters, kune rumwe rutivi, inogadzirwa nemishonga inofananidzira migumisiro ye ketosis, ichipa muviri simba rakananga nenzira yeketoni.
Saka, chii chinoita kuti ketone esters ine simba? Imwe yemabhenefiti makuru eketone esters kugona kwayo kukurumidza kuwedzera mazinga eropa ketone, ichipa muviri nekukurumidza uye kunoshanda sosi yesimba. Izvi zvinonyanya kubatsira kune vatambi uye vanhu vanotarisa kuvandudza maitiro avo emuviri, sezvo ketoni inogona kushandiswa seyakachena-inopisa mafuta kune misumbu uye uropi, nekudaro kuwedzera kutsungirira, kuderedza kuneta, nekuvandudza kupora. Mukuwedzera kune maitiro avo-enhanting migumisiro, ketone esters yakaratidzwa kuva neuroprotective properties.
Pamusoro pezvo, ketone esters yakadzidzwa nezve mukana wavo muhutano hwemetabolism, kunyanya mukutarisira kufutisa uye chirwere cheshuga. Nekusimudzira kugona kwemuviri kunyatsopisa mafuta ehuni, ketone esters inogona kubatsira kuvandudza insulin senitivity, kudzora mazinga ehuga uye kukurudzira kurasikirwa.
Kutanga, tinotanga ne esters. Esters zvinhu zvakaumbwa zvinoumbwa apo madoro anoita necarboxylic acids. Kuita uku kunoguma nekuumbwa kwemorekuru rine carbon-oxygen double bond (C=O) uye oxygen imwe bond neimwe carbon atomu. Ester inozivikanwa nekunhuhwirira kwayo, ine muchero uye inowanzoshandiswa mukugadzira zvinonhuwira uye zvinonhuwirira.
Ketoni, kune rumwe rutivi, organic compounds ine carbonyl boka (C=O) yakasungirirwa kumaatomu maviri ecarbon. Kusiyana nemaester, ketoni hadzina atomu yehydrogen yakasungirirwa kucarbonyl carbon. Ketoni dzinowanzowanikwa mumasikirwo uye dzinoshandiswawo mune zvakasiyana-siyana zvemabhizimisi uye zvekutengeserana.
Imwe misiyano mikuru pakati peesters neketoni ndiyo chimiro chavo chemakemikari uye mapoka anoshanda. Kunyange zvazvo makomisheni ese ari maviri aine boka recarbonyl, mabatiro anoita boka recarbonyl kune mamwe maatomu anoita kuti asiyane kubva kune mumwe. Mune esters, boka re carbonyl rinosungirirwa kune imwe atomu yeokisijeni uye imwe kabhoni atomu, nepo mumaketoni, boka re carbonyl rinosungirirwa kune maviri maatomu e carbon.
Imwe misiyano yakakosha pakati peesters neketoni ndeye reactivity yavo uye makemikari zvinhu. Ester inozivikanwa nekunhuhwirira kwayo uye inowanzoshandiswa semafuta uye zvinonhuwira. Ivo zvakare vane mapoinzi akaderera ekubikira zvichienzaniswa neketoni. Ketones, kune rumwe rutivi, ane nzvimbo yepamusoro yekubikira uye anowedzera kuita nekuda kwekuvapo kweboka re carbonyl rakasungirirwa kumaatomu maviri e carbon.
Panyaya yekushandiswa kwavo, esters uye ketoni zvine maitiro akasiyana. Esters inowanzoshandiswa mukugadzirwa kwezvinonhuwira, zvinonhuhwirira uye zvizorwa, nepo ketoni dzichishandiswa muzvinonyungudutsa, mishonga uye maindasitiri maitiro. Kunzwisisa iyo yakasarudzika zvivakwa uye reactivity yeaya makomisheni kwakakosha kune akasiyana maapplication avo.
Autophagy inzira yemasero iyo masero anojekesa akakuvadzwa organelles uye mapuroteni kuchengetedza hutano. Zvinotendwa kuti kusimudzira autophagy kunogona kuve nehuwandu hwehumwe hutano hunobatsira, sekuwedzera hupenyu, kuderedza njodzi yezvimwe zvirwere, uye kutsigira kwese cellular basa. Ketoni, kune rumwe rutivi, makemikari anogadzirwa apo muviri unogadzirisa mafuta nokuda kwesimba pasina makabhohaidhiretsi akakwana. Iwo akabatanidzwa kune akasiyana ehutano mabhenefiti, anosanganisira kunatsiridza kujeka kwepfungwa, kurasikirwa nehuremu, uye hutano hwemetabolism.
Tsvagiridzo inoratidza kuti ketoni dzinogona kuve nebasa mukusimudzira autophagy. Chidzidzo chakabudiswa mumagazini chakawana kuti ketoni, kunyanya beta-hydroxybutyrate (BHB), inogona kuita zvakananga nzira mumasero ane basa rekutanga nekugadzirisa autophagy. Izvi zvinoratidza kuti mazinga eketone akakwirira anokonzerwa nekudya kwe ketogenic kana nguva yekutsanya inogona kutsigira muviri wepanyama autophagy process.
Uyezve, ketoni dzakaratidzwa kuti dzinokanganisa kutaura kwemamwe majini uye mapuroteni anobatanidzwa mu autophagy. Mune imwe tsvakurudzo, vatsvakurudzi vakawana kuti BHB inogadzirisa kutaura kwemajini ane chokuita ne autophagy mumasero emagetsi, zvichiratidza kuti inogona kuita basa mukusimudzira iyi cellular process.
Uyezve, ketoni dzakawanikwa dziine anti-inflammatory uye antioxidant properties, zvose zviri zviviri zvakabatana ne autophagy process. Kuzvimba kusingaperi uye oxidative kusagadzikana inokanganisa autophagy, zvichitungamira mukuunganidzwa kweakakuvadzwa cellular zvikamu uye zvinogona kubatsira mukukura kwezvirwere zvakasiyana. Nekudzikisa kuzvimba uye oxidative kusagadzikana, ketoni dzinotsigira kugona kwemuviri kunyatsoita autophagy uye kuchengetedza hutano hweserura.
Zvisinei, zvakakosha kuziva kuti nepo ketoni inogona kuva nekwanisi yekuwedzera autophagy, nzvimbo yavanogadzirwa inokosha. Semuenzaniso, yakakwirira ketone mazinga kuburikidza nekudya kwekudya ketosis, kutsanya, kana exogenous ketone supplementation inogona kutsigira autophagy, asi ketoni inogadzirwa nekuda kwechirwere cheshuga chisingadzoreki (diabetic ketoacidosis) haina hutano hwakafanana hunosimudzira migumisiro uye inogona kukuvadza.
Ketone esters makemikari ane ketone boka, rinova boka rinoshanda rine boka re carbonyl (C=O) rakasungirirwa kumaatomu maviri ecarbon. Kana ikanyudzwa, izvi zvinosanganiswa zvinokurumidza kushandurwa kuita ketoni, ayo ari mamorekuru akakosha anoshanda seimwe simba sosi yemuviri uye uropi, kunyanya panguva dzekudzikisa carbohydrate kushandiswa. Izvi zvinoita kuti ketone esters ive sarudzo yakakurumbira kune vanhu vanotevera ketogenic kudya kana kutarisa kuwedzera kushanda kwemuviri nepfungwa.
Kune akawanda marudzi eketone esters pamusika, imwe neimwe iine yayo yakasarudzika midziyo uye inogona kushandiswa. Mamwe emhando dzakajairika anosanganisira:
1.Acetoacetate: Acetoacetate ndiyo inonyanya kuzivikanwa mhando yeketone ester. Kazhinji inotorwa kubva kuacetoacetate, ivo vanozivikanwa nekukwanisa kwavo kukurumidza kusimudza mazinga eropa ketone, vachipa kukurumidza sosi yesimba kumuviri uye uropi. Vatambi uye vanhu vanowanzo shandisa acetoacetate kuti vawedzere kuita kwavo kwemuviri uye kutsungirira.
2.Beta-hydroxybutyrate: Beta-hydroxybutyrate (BHB) imwe mhando yakakurumbira yeketone ester. BHB ndeimwe yematatu matatu eketone anogadzirwa panguva ye ketosis uye inoonekwa seyakanyanya kugadzikana uye inoshanda sosi yesimba kupfuura acetoacetate. BHB esters inowanzoshandiswa neavo vanoda kutsigira kujeka kwepfungwa, kuisa pfungwa, uye basa rose rekuziva.
3.Mixed Ketone Esters: Mamwe ketone esters anogadzirwa pamwe nekubatanidzwa kweacetoacetate uye BHB, kupa nzira yakaenzana yekuwedzera mazinga eketone mumuviri. Aya ma hybrid ketone esters anokosheswa nekugona kwavo kupa simba nekukurumidza uye rinoramba riripo, zvichiita kuti ive sarudzo inogoneka kune dzakasiyana siyana dzekushandisa.
4.New ketone esters: Mumakore achangopfuura, vatsvakurudzi vanga vachishanda mukugadzira ketone esters itsva nekuwedzera bioavailability uye kushanda. Aya matsva ketone esters anogona kuvandudza kuravira, kushivirira uye kunyura, zvichiita kuti zvive zvakanyanya kukodzera kushandiswa nguva dzose.
Kuti unzwisise zvingangobatsira zveketone esters, zvakakosha kuti utange wanzwisisa kuti chii. Ketone esters makemikari ane ketoni, ari organic mamorekuru anogadzirwa nechiropa kana muviri uri mu ketosis. Ketosis inoitika apo muviri unopisa mafuta sehuni panzvimbo pemacarbohydrates, anogona kuitika panguva yekutsanya, kurovedza muviri kwenguva refu, kana kudya kwakaderera-carbohydrate.
Chimwe chezvikonzero zvakakosha ketone esters yakaunza kufarira kwakawanda ndiko kugona kwavo kupa muviri nekukurumidza sosi yesimba. Kana muviri uri mu ketosis, unoburitsa miviri ye ketone seimwe nzira yehuni yekuisa glucose. Mushure mekudya, ketone esters inokurumidza kupinda muropa uye inoshandurwa kuva ketoni, iyo inogona kushandiswa nemuviri sehuni. Izvi zvinonyanya kubatsira kune vatambi kana vanhu vanotarisa kuti vavandudze maitiro avo emuviri, sezvo ketoni inopa nguva yakareba-yakareba uye inobudirira fomu yesimba kana ichienzaniswa neglucose.
Pamusoro pekugona kwavo kuwedzera mazinga emagetsi, ketone esters yakadzidzwawo nekuda kwekuziva kwavo-kunatsiridza mhedzisiro. Tsvagiridzo inoratidza kuti ketoni dzinogona kuyambuka chivharo cheropa-uropi uye kushandiswa nehuropi sechitubu chesimba, izvo zvinogona kubatsira kunatsiridza kutarisa, kutarisa, uye kujeka kwepfungwa. Zvimwe zvidzidzo zvinotoratidza kuti ketoni inogona kunge iine neuroprotective properties, ichivaita chishandiso chinogona kutsigira hutano hwehuropi uye kushanda.
Kutarisira uremu uye hutano hwemetabolism. Sezvo ketone esters ichikurudzira ketosis, inogona kubatsira kuderedza uremu nekusimudzira kupisa kwemafuta uye kuderedza kudya. Uyezve, ketone esters inogona kuva nemigumisiro yakanaka pamazinga eshuga yeropa uye insulin senitivity, zvichiita kuti zvive zvakakosha kune vanhu vane chirwere cheshuga chechipiri kana metabolic syndrome.
Asi zvichida chimwe chezvinonyanya kufadza zvinogona kubatsira ketone esters ndiko kukwanisa kwavo kutevedzera zvinokonzerwa nekutsanya. Kutsanya kwakaratidzwa kuve kune hutano hwakasiyana-siyana hunobatsira, kusanganisira kuvandudzwa kwehutano hwemetabolism, huremu hwekutonga, uye hupenyu hurefu. Nekupa muviri kune chitubu cheketoni, ketone esters inogona kukwanisa kuburitsa mamwe emhedzisiro yekutsanya pasina kutsanya chaiko.
Ketone esters vari kudzidzwawo nekuda kwekugona kwavo mukuvandudza hutano hwemoyo. Imwe tsvakurudzo inoratidza kuti ketone esters inogona kuva nemigumisiro yakanaka pamazinga echolesterol uye kuwedzera kweropa, izvo zvingaita kuti zvive zvinobatsira kuhutano hwemwoyo. Zvisinei, kutsvakurudza kwakawanda kunodiwa munzvimbo ino kuti unzwisise zvizere zvinokonzerwa neketone esters pahutano hwemwoyo.
Ngatitangei kutsanangura kuti ketone esters chii. Ketone esters ndeye exogenous ketoni iyo inogona kubatsira muviri kupinda ketosis nekukurumidza kana ichitorwa sekuwedzera. Ivo vanowanzoshandiswa nevamhanyi uye vanhu vari kutsvaga nzira yekuwana ketosis nekukurumidza pasina kunyatsoomerera kune yakaderera-carb, yakakwira-mafuta kudya. Kudya kwechinyakare ketogenic, kune rumwe rutivi, kunosanganisira kuomarara kwekudya kunoda kuti vanhu vadye chikafu chine mafuta ane hutano, ane mwero muprotein, uye akaderera kwazvo mumacarbohydrates.
Ketoesters inoratidzika seyakanaka sarudzo kune avo vari kutsvaga kukurumidza, nzira iri nyore yekuwana ketosis pasina kuchinja zvachose kudya kwavo. Nekutora exogenous ketones, muviri unogona kupinda munzvimbo ye ketosis pasina kunyatsoomerera kune yakaderera-carb, yakakwira-mafuta kudya. Izvi zvinonyanya kubatsira kune vatambi uye vanhu vari kutsvaga kuvandudza maitiro avo emuviri uye kutsungirira.
Nekudaro, zvakakosha kuti uzive kuti nepo ketone esters inogona kubatsira vanhu kupinda ketosis nekukurumidza, haisi kutsiva kune hutano, kudya kwakaringana. Kudya kwechinyakare ketogenic kwakaratidzwa kuve neakawanda hutano mabhenefiti kunze kwekuremerwa uremu, kusanganisira yakagadziridzwa insulin senitivity, kudzikira kuzvimba, uye kujeka kwepfungwa. Nokuomerera kune ketogenic kudya, vanhu vanogonawo kuona kuchinja kwenguva refu mumetabolism iyo inogona kuva nemigumisiro yekusingaperi pahutano hwavo hwose uye hukama hwakanaka.
Sarudzo pakati pe ketogenic uye yechinyakare ketogenic chikafu chinodzika kune zvaunofarira uye zvinangwa. Kana iwe uchitsvaga nzira yekuwana ketosis nekukurumidza kana kuwedzera mashandiro emuviri, ketone esters inogona kunge iri sarudzo yakakunakira iwe. Nekudaro, kana iwe uchitsvaga yakagadzikana, yenguva refu nzira yekuvandudza hutano hwako uye kugara zvakanaka, yechinyakare ketogenic chikafu chingave chiri nani sarudzo.
Zvakakosha kuyeuka kuti zvakanaka kubvunza nyanzvi yezvehutano kana nyanzvi yezvekudya usati waita chero shanduko huru yekudya. Vanogona kupa kurudziro yemunhu zvichienderana nehutano hwako, zvinangwa, uye zvekudya zvaunofarira.
Mubvunzo: Chii chinonzi ketone ester uye inoshanda sei?
A: Ketone ester ndeyekuwedzera inopa muviri neketoni, iyo inogadzirwa zvakasikwa nechiropa panguva yekutsanya kana kuderera kwecarbohydrate. Kana ikabatwa, ketone ester inogona kukurumidza kusimudza mazinga eketone yeropa, ichipa muviri kune imwe nzvimbo yemafuta kune glucose.
Mubvunzo: Ndingaisa sei ketone ester muhupenyu hwangu hwezuva nezuva?
A: Ketone ester inogona kuiswa muhutano hwako hwezuva nezuva nekuitora mangwanani sechigadziro chekutanga chekushanda, kuishandisa kuti uwedzere kushanda kwepfungwa uye kuisa pfungwa panguva yebasa kana zvidzidzo zvekudzidza, kana kuipedza sechibatsiro chekudzorera shure kwekushanda. Inogonawo kushandiswa sechishandiso chekushandura mukudya kwe ketogenic kana kutsanya kwepakati.
Mubvunzo: Pane here mhedzisiro kana zvidziviriro zvekufunga kana uchishandisa ketone ester?
A: Kunyange zvazvo ketone ester inowanzoonekwa yakachengeteka kune vanhu vakawanda, vamwe vanhu vanogona kusangana nekusagadzikana kwepamuviri pavanotanga kuishandisa. Zvakakoshawo kubvunzana nenyanzvi yezvehutano usati waisa ketone ester mumuitiro wako, kunyanya kana uine chero mamiriro ezvinhu ehutano huri pasi kana uri kutora mishonga.
Mubvunzo: Ndingaita sei kuti ndiwedzere migumisiro yekushandisa ketone ester?
A: Kuti uwedzere migumisiro yekushandisa ketone ester, zvakakosha kubatanidza kushandiswa kwayo nemararamiro ane hutano anosanganisira nguva dzose kurovedza muviri, hydration yakakwana, uye kudya kwakakwana. Pamusoro pezvo, kutarisisa kunguva yekushandiswa kweketone ester zvine chekuita nemabasa ako nezvinangwa zvinogona kubatsira kukwirisa mhedzisiro yayo.
Disclaimer: Ichi chinyorwa ndecheruzivo rwese chete uye hachifanirwe kutorwa sechero zano rekurapa. Imwe yeruzivo rweblog post runobva kuInternet uye haina hunyanzvi. Iyi webhusaiti inongova nebasa rekugadzirisa, kufomatidza uye kugadzirisa zvinyorwa. Chinangwa chekuendesa rumwe ruzivo hachirevi kuti unobvumirana nemaonero ayo kana kusimbisa uchokwadi hwezvirimo. Nguva dzose bvunza nyanzvi yezvehutano usati washandisa chero chekuwedzera kana kuita shanduko kuhutano hwako hwehutano.
Nguva yekutumira: Jan-12-2024
