Munyika yanhasi inomhanya-mhanya, zvakakosha kuti tikoshese hutano hwedu nekugara zvakanaka. Nemarongero akabatikana uye mararamiro akabatikana, zvinogona kunetsa kuona kuti tiri kupa miviri yedu chikafu chavanoda kuti ishande nemazvo. Apa ndipo panouya spermidine supplement. Kuwedzera ne spermidine kunogona kubatsira kutsigira kuvandudzwa kwesero, kunatsiridza hutano hwemoyo, uye kunyange kubatsira kugona kwekuziva, zvichiita kuti iyi yemusikirwo iwedzere kukosha kuhutano hwako hwezuva nezuva.
Spermidine inonzi polyamine inowanzoitika inowanikwa mumasero mapenyu ose, kusanganisira zvirimwa nemhuka. Inobata basa rinokosha mumabasa akasiyana-siyana emasero, kusanganisira kukura kwesero, kuwanda uye kukwegura, uye sezvatinokura, mazinga espermidine mumitumbi yedu anoderera.
Chaizvoizvo, autophagy inzira yekuchengetedza imba inoita kuti muviri ubvise organelles dzakasakara, mapuroteni asina kurongeka, uye mamwe marara emasero. Nekuita kudaro, inobatsira kuchengetedza kutendeseka kwemasero edu uye matishu, kuve nechokwadi chekushanda kwavo kwakakwana. Nekudaro, mabhenefiti e autophagy anowedzera kupfuura kuchengetedza, sezvo maitiro aya akaratidzwa kuita basa rekudzivirira mune dzakasiyana siyana zvirwere. Semuyenzaniso, tsvagiridzo inoratidza kuti kukwidziridzwa autophagy kunogona kubatsira kudzikisira kufambira mberi kwezvirwere zveurourodegenerative senge Alzheimer's neParkinson's chirwere nekubvisa chepfu mapuroteni aggregates anokonzeresa kukuvadzwa neuronal.
Uye zvakare, autophagy ine hukama nekudzora kwesimba revanhu metabolism, kunyanya panguva dzekushomeka kwekudya kunovaka muviri kana metabolic kusagadzikana. Mukushaikwa kwekudya kwakakwana, maseru anogona kuvimba neautophagy kuputsa zvikamu zvawo uye kugadzira mafuta anodiwa kuchengetedza zvakakosha cellular mabasa. Iyi mhinduro inogadzirisa inobvumira muviri kurarama nenguva yekutsanya kana kurambidzwa kwecalorie, uye inogona zvakare kubatsira kune hutano mabhenefiti anocherechedzwa nekutsanya kwepakati kana ketogenic kudya, izvo zvakaratidzwa kukurudzira Autophagy.
Tsvagiridzo inoratidza kuti spermidine inogona kubatsira kutsigira echisikigo autophagy process, cellular process inobvisa akakuvadzwa kana masero ekare kuti awane nzvimbo kune matsva. Nekusimudzira autophagy, spermidine supplements inogona kubatsira kutsigira kuchembera kune hutano uye hupenyu hurefu.
Pamusoro pezvo, spermidine supplements zvakaratidzwa kuve zvine mabhenefiti ehutano hwemoyo. Tsvagiridzo inoratidza kuti spermidine inogona kubatsira kuchengetedza hutano hweropa, cholesterol mazinga uye hutano hwemoyo wese. Pamusoro pezvo, spermidine yakawanikwa iine antioxidant zvivakwa zvinogona kubatsira kudzivirira muviri kubva kune oxidative kusagadzikana uye kuzvimba.
Spermidine musanganiswa wechisikigo unowanikwa muzvikafu zvakaita sesoya beans, howa, uye chembere chizi. Nekuda kweiyo inogona kurwisa kuchembera mhedzisiro. Tsvagiridzo inoratidza kuti spermidine inogona kubatsira kusimudzira sero uye tishu patsva, izvo zvakakosha pakuchengetedza chitarisiko chepwere uye hutano hwese.
Imwe yedzakakosha nzira spermidine inoderedza kuchembera ndeyekukurudzira iyo autophagy maitiro. Autophagy inzira yemuviri yekubvisa masero akakuvadzwa kana ekare uye kuatsiva nemasero matsva ane hutano. Sezvo isu tichikura, maitiro emuviri wedu echisikigo autophagy maitiro anova mashoma kushanda, zvichitungamira kuunganidzwa kweakakuvadzwa maseru nematishu. Spermidine yakaratidzwa kuwedzera autophagy, iyo inogona kubatsira kudzivirira kuderera kwezera-kwezera musero basa.
Mukuwedzera pakusimudzira autophagy, spermidine yakaratidzwa kuva ne-anti-inflammatory uye antioxidant properties. Kuzvimba kusingagumi uye kushushikana kweiyo oxidative zvinhu zviviri zvakakura mukuchembera, uye kugona kwespermidine kurwisa izvi zvinogona kubatsira kunonoka kuchembera padanho remasero.
1. Anti-aging effect
Spermidine musanganiswa wepoliamine unowanikwa mune zvakasiyana siyana zvekudya, senge gorosi, soya beans, uye mamwe marudzi ehowa. Inobata basa rakakosha mukukura kwesero uye kupatsanurwa uye kuchengetedza kushanda kwesero. Sezvatinokura, miviri yedu inobereka zvishoma spermidine, izvo zvinogona kutungamirira kuderera kwehutano hwesero uye kushanda.
Tsvagiridzo inoratidza kuti spermidine supplementation inogona kunge ine anti-kuchembera mhedzisiro panhengo dzakasiyana siyana uye masisitimu emuviri. Tsvagiridzo yakabudiswa mupepanhau Nature Medicine yakawana kuti spermidine supplementation yakabatana nehupenyu hwakareba uye nekuvandudza hutano hwemoyo mumakonzo. Pamusoro pezvo, spermidine yakaratidzwa kukurudzira autophagy, nzira yemuviri yemusikirwo yekubvisa masero akakuvadzwa uye kuvandudza matsva. Nokusimudzira chirongwa ichi, spermidine inogona kubatsira kuderedza kukwegura, izvo zvinokosha pakuchengetedza masero maduku, ane utano.
2. Kuvandudza hutano hwemwoyo
Ongororo dzinoverengeka dzakaongorora hukama hunogona kuitika pakati pespermidine uye hutano hwemoyo, nemhedzisiro inokurudzira. Chidzidzo chakabudiswa mumagazini Nature Medicine chakawana kuti mbeva dzaidyisa kudya kwepamusoro-spermidine kwakavandudza kushanda kwemoyo uye kurarama 25% kwenguva refu. Chimwe chidzidzo chakabudiswa mu Journal of the American Heart Association chakawana kuti mazinga epamusoro ezvokudya zvespermidine akabatanidzwa nengozi yakaderera yekushaya mwoyo muvanhu.
Spermidine ine antioxidant uye anti-inflammatory properties, iyo inokosha pakuchengetedza hutano hwemwoyo. Oxidative kusagadzikana uye kuzvimba zvinhu zvinozivikanwa kuti zvinobatsira mukusimudzirwa kwechirwere chemoyo, uye nekudzikisa maitiro aya, spermidine inogona kubatsira kuvandudza hutano hwemoyo nekudzikisa njodzi yechirwere chemoyo uye kuvandudza basa rose remoyo. Kuwedzera kutsvagisa kunoratidza kuti spermidine inogona kubatsira kudzivirira atherosclerosis, chirwere umo plaque inovaka mutsinga, zvichiita kuti kuwedzere njodzi yekurova kwemoyo uye sitiroko.
Chidzidzo chakabudiswa mupepanhau Nature Medicine chakawana kuti kuwedzera mbeva ne spermidine kwakaderedza atherosclerotic plaque kugadzirwa uye kwakavandudza hutano hwemoyo. Uhu humbowo hunovimbisa hwekuti spermidine ine inodzivirira pamwoyo.
Mukuwedzera kune zvingave zvinobatsira mukudzivirira atherosclerosis, spermidine yakaratidzawo kuva nemigumisiro yakanaka pakushanda kwemwoyo. Tsvagiridzo yakawana kuti spermidine supplementation inovandudza kugona kwemoyo kubatirana uye kuzorora, izvo zvakakosha pakuchengetedza hutano kuyerera kweropa uye nemoyo wese basa.
3. Kuvandudza basa rekuziva
Tsvagiridzo inoratidza kuti spermidine inogona kuita basa rakakosha mukutsigira kugona kwekuziva. Spermidine ine neuroprotective mhedzisiro, kusanganisira kusimudzira kugona kwekuita uye kuderedza njodzi yezera-inoenderana nekuderera kwekuziva. Idzi inhau dzinonyanya kunakidza kune vanhu vachembera, sezvo kuchengetedza ruzivo rwekuziva sezvo isu takura chinhu chakakosha kune vanhu vazhinji.
Mukuwedzera kune uropi-hutano-hunokurudzira migumisiro, spermidine yakaratidza kuva ne-anti-inflammatory uye antioxidant properties, iyo yose inokosha pakuchengetedza hutano hwehuropi. Kuzvimba kusingaperi uye kushushikana kweoxidative kunofungidzirwa kuti kunobatsira mukuderera kwekuziva, saka kugona kwespermidine kurwisa zvinhu izvi kunogona kuve nekukanganisa kwakakosha pahutano hwehuropi.
4. Kuderera kweshuga yeropa
Tsvagiridzo inoratidza kuti spermidine inogona kuita basa mukuvandudza insulin senitivity, iyo yakakosha pakuchengetedza hutano hwehuga hweropa. Insulin senitivity inoreva kugona kwemuviri kupindura insulin, iyo hormone ine basa rekudzora shuga yeropa. Kana muviri unenge usisina kugadzikana ne insulin, huwandu hweshuga hweropa hunokwira, zvichitungamira kune huwandu hwezvinetso zvehutano zvinosanganisira chirwere cheshuga uye chirwere chemoyo.
Chidzidzo chakabudiswa mupepanhau Nature Communications chakawana kuti spermidine supplementation yakavandudza insulin senitivity muvanhu vakuru vezera repakati. Vatori vechikamu vakatora spermidine kwemwedzi mitatu vakawana kuvandudzwa kwakakosha mumazinga eshuga yeropa zvichienzaniswa nevaya vakatora placebo. Izvi zvakawanikwa zvinoratidza kuti spermidine inogona kuve chishandiso chinovimbisa chekudzora mazinga eshuga, kunyanya kune avo vari panjodzi yekubatwa nechirwere cheshuga.
Saka spermidine inoshandisa sei mhedzisiro yayo pamazinga eshuga yeropa? Imwe nzira inogoneka kugona kwayo kusimudzira autophagy - maitiro emuviri emusikirwo ekupwanya uye kudzokorora maseru akare kana akakuvadzwa. Autophagy inotora basa rakakosha mukuchengetedza hutano hwesero uye kushanda, uye dysregulation yeiyi maitiro kwave kwakabatana ne insulin kuramba uye chirwere cheshuga. Spermidine yakaratidzwa kuwedzera autophagy, iyo inogona kuvandudza insulin senitivity uye glycemic control.
5. Kutsigira kwekudzivirira muviri
Zvidzidzo zvakawana kuti spermidine inogona kutsigira immune system uye kubatsira muviri kurwisa hutachiona uye zvirwere. Inoshanda nekusimudzira kugadzirwa uye kushanda kwemasero ekudzivirira, pamwe nekuderedza kuzvimba mumuviri. Izvi zvinobatsira kuvandudza huwandu hwese immune system uye kuderedza kurwara.
Spermidine, musanganiswa wepolyamine unowanikwa mumasero mapenyu ese, inozivikanwa nekuda kwehutano hwayo hunogona kubatsira, kusanganisira anti-kuchembera uye kusadzivirirwa kwemuviri. Vanhu vazhinji vanotanga kushandisa spermidine supplements kuti vaise komisheni iyi mumaitiro avo ezuva nezuva. Asi zvinotora nguva yakareba sei kuti spermidine ishande?
Spermidine inoshanda nekuita chirongwa mumasero anonzi autophagy, inova nzira yemuviri yekubvisa masero akakuvadzwa uye kuvandudza matsva. Iyi nzira yakakosha pakuchengetedza hutano hweserura uye inofungidzirwa kuita basa mukukwegura. Nekusimudzira autophagy, spermidine inogona kubatsira kukurudzira kuvandudzwa kwesero, kuvandudza hutano hwese, uye zvinogona kunonoka kuchembera.
Kana zvasvika kune nguva yekuita kwespermidine, zvakakosha kufunga kuti mhinduro dzega dzinogona kusiyana. Zvinhu zvakadai sezera, hutano hwese, uye dosi zvese zvinogona kukanganisa kuti spermidine inotora nguva yakareba sei kushanda. Vamwe vanhu vanogona kuona mhedzisiro nekukurumidza, nepo vamwe vanogona kutora nguva yakareba kuti vaone mabhenefiti.
Kazhinji kutaura, tsvakiridzo inoratidza kuti spermidine supplementation inogona kuburitsa zvinooneka mukati memavhiki kusvika kumwedzi. Chidzidzo che2018 chakaburitswa mujenari Nature Medicine chakawana kuti spermidine supplementation yakavandudza kushanda kwemoyo uye nekuwedzera hupenyu mumakonzo akura. Kunyangwe chidzidzo ichi chakaitwa mumakonzo, chinopa ruzivo rwakakosha mune zvinogona kuitika zvespermidine pamatanho ane chekuita nekuchembera.
Chidzidzo chevanhu cha2018 chakaburitswa mujenari Kuchembera kwakaratidzawo mabhenefiti ekuwedzera spermidine. Zvidzidzo zvakawana kuti vanhu vakatora spermidine supplements kwemwedzi mitatu vakawana kuvandudzwa kweropa uye hutano hwemoyo zvichienzaniswa nevaya vasina kutora zvekuwedzera.
1. Wana zvemhando yepamusoro mbishi
Paunosarudza spermidine supplement, unofanira kunyatsoongorora zvigadzirwa zvayo. Tsvaga yekuwedzera iyo isina mafirita, mavara ekugadzira, uye anochengetedza. Nenzira yakanaka, ma supplements anofanirwa kugadzirwa kubva kune organic uye asiri-GMO masosi kuve nechokwadi kuchena uye potency.
2. Funga kunobva spermidine
Spermidine inogona kutorwa kubva kune zvakasiyana-siyana zvechisikigo, zvakadai segorosi germ, soya bhinzi, uye mhodzi dzenhanga, pamwe chete nemakomisheni ekugadzira anopinda maitiro ekunatsa. Mabhenefiti ega ega ega anogona kusiyanisa zvishoma, saka zvakakosha kufunga kwakabva spermidine mune yako yekuwedzera. Vamwe vanhu vanogona kunge vasingawirirani nezvimwe zvinhu, saka zvakakosha kuti usarudze chekuwedzera chinoenderana nezvido zvako zvekudya.
3. Tarisa spermidine content
Kushanda kwe spermidine supplements kunosiyana kubva kune chigadzirwa kune chigadzirwa. Izvo zvakakosha kuti utarise iyo spermidine yemukati yesevhisi yega yega kuti uve nechokwadi chekuti uri kuwana dosi inoshanda. Tarisa ma supplements anopa huwandu hwakakwana hwespermidine kutsigira hutano hwako zvinangwa. Uyezve funga nezve bioavailability yespermidine, sezvo izvi zvichikanganisa mabatirwo aanoitwa uye kushandiswa nemuviri.
4. Ongorora mhando uye mukurumbira wechiratidzo
Paunosarudza spermidine supplement, zvakakosha kufunga nezvemukurumbira wemugadziri. Tsvaga kambani yakazvipira kune mhando, pachena, uye kuchengeteka. Tsvakurudza maitiro ekugadzira, zvitupa, uye ongororo yevatengi kuti uone huwandu hwese hwezvigadzirwa zvayo.
5. Bvunza nyanzvi yezveutano
Zvakakosha kubvunza nyanzvi yezvehutano usati waisa chero mitsva yekuwedzera mumaitiro ako ezuva nezuva, kunyanya kana uine chero mamiriro ehutano ari pasi pehutano kana uri kutora mishonga. Vanogona kupa hutungamiriri hwemunhu uye mazano zvichienderana nezvinodiwa nehutano hwako.
Suzhou Myland Pharm & Nutrition Inc. yave ichiita bhizinesi rekuwedzera chikafu kubva muna 1992. Ndiyo kambani yekutanga muChina kugadzira nekutengesa mhodzi dzemazambiringa.
Iine makore makumi matatu echiitiko uye ichitungamirwa nehunyanzvi hwepamusoro uye yakagadziridzwa zvakanyanya R&D zano, kambani yakagadzira mhando yezvigadzirwa zvemakwikwi uye ikava yekuvandudza hupenyu hwesainzi yekuwedzera, yetsika synthesis uye kambani yekugadzira masevhisi.
Pamusoro pezvo, kambani iyi zvakare FDA-yakanyoreswa mugadziri, inovimbisa hutano hwevanhu nemhando yakagadzikana uye kukura kwakasimba. Zviwanikwa zvekambani zveR&D uye zvivakwa zvekugadzira uye zviridzwa zvekuongorora ndezvemazuva ano uye zvinoshanda, uye zvinokwanisa kugadzira makemikari pamilligram kusvika toni sikero zvichiteerana neISO 9001 zviyero uye GMP maitiro ekugadzira.
Mubvunzo: Chii chinonzi spermidine uye nei yakakosha kune hutano?
A: Spermidine i polyamine inongoitika yechisikigo inoita basa rakakosha mumaserura akasiyana siyana, kusanganisira autophagy uye protein synthesis. Yakaratidzwa kuva ne-anti-aging and health-promotion properties, zvichiita kuti ive chinhu chinokosha chehutano hwakanaka.
Mubvunzo: Ndingabatanidza sei spermidine supplements mumaitiro angu ezuva nezuva?
A: Spermidine supplements inowanikwa nenzira dzakasiyana-siyana, kusanganisira capsules, powders, uye zvokudya zvekudya zvakadai segorosi uye soya. Iwe unogona kuvabatanidza mumuitiro wako wezuva nezuva nekuvatora sezvakarayirwa papepa, kana nekuwedzera spermidine-rich food pakudya kwako.
Mubvunzo: Zvinotora nguva yakareba sei kuti uone zvikomborero zve spermidine supplementation?
A: Nguva yekuona mabhenefiti e spermidine supplementation inogona kusiyana kubva kumunhu kuenda kumunhu. Vamwe vanhu vanogona kuona kuvandudzwa kwehutano hwavo hwese mukati memavhiki mashoma ekushandisa nguva dzose, asi vamwe vanogona kutora nguva yakareba kuti vaone mhedzisiro.
Disclaimer: Ichi chinyorwa ndecheruzivo rwese chete uye hachifanirwe kutorwa sechero zano rekurapa. Imwe yeruzivo rweblog post runobva kuInternet uye haina hunyanzvi. Iyi webhusaiti inongova nebasa rekugadzirisa, kufomatidza uye kugadzirisa zvinyorwa. Chinangwa chekuendesa rumwe ruzivo hachirevi kuti unobvumirana nemaonero ayo kana kusimbisa uchokwadi hwezvirimo. Nguva dzose bvunza nyanzvi yezvehutano usati washandisa chero chekuwedzera kana kuita shanduko kuhutano hwako hwehutano.
Nguva yekutumira: Jan-24-2024
