Kana zvasvika pakuchengetedza mararamiro ane hutano, zvakakosha kuti titarise zvese zvehutano nekudya. Kubatanidza evodiamine supplement muhutano hwako uye chirongwa chekudya kunogona kuva nzira yakanaka yekutsigira hutano hwako hwose uye kugara zvakanaka. Kunyangwe iwe uchida kudzora uremu hwako, kutsigira kugaya zvine hutano, kana kuwedzera basa remoyo, evodiamine inogona kubatsira. Evodiamine chinhu chakasikwa chinowanikwa mumuchero wemuti weEvodia. Yakashandiswa mumishonga yechinyakare yeChinese kwemazana emakore uye inozivikanwa nekugona kwayo hutano hunobatsira.
Evodiamine inorondedzerwa sebioactive alkaloid uye inowanikwa mumichero yeEvodiamine chirimwa. Izvi zvinoreva kuti ine kugona kudyidzana neakasiyana biological process mumuviri. Ichi chikamu chakadzidzwa nekuda kwezvinogona kuitika pametabolism, huremu hwekutonga, uye hutano hwese. Muchivanhu cheChinese mushonga, evodiamine inoshandiswa kutsigira kugaya, kubvisa marwadzo, uye kukurudzira kuenzana kwesimba. Mukutsvakurudza kwemazuva ano, evodiamine yakadzidzwa nokuda kwekugona kwayo se thermogenic, zvinoreva kuti inogona kuva nekwanisi yekuwedzera kugadzirwa kwemuviri kwekupisa uye kushandiswa kwesimba.
Zvimwe zvidzidzo zvinoratidza kuti evodiamine inogona kuva nekwaniso yekuwedzera chiyero chemetabolism yemuviri, zvichiita kuti mari yakawanda yekoriori uye inogona kuderedza uremu. Pamusoro pezvo, evodiamine yakadzidzwa nekuda kwekugona kwayo kukurudzira kusviba kwechena adipose tishu, izvo zvingave zvine chekuita nekuvandudza hutano hwemetabolism uye kuderedza njodzi yezvirwere zvine chekuita nekufutisa.
Zvinozivikanwa kuti kuzvimba uye kushushikana kweiyo oxidative kunobata basa mukuvandudzwa kwezvirwere zvakasiyana siyana zvisingaperi, saka makomisheni anokwanisa kurwisa maitiro aya anofarira zvikuru kune vaongorori nenyanzvi dzehutano. Imwe tsvagiridzo inoratidza kuti evodiamine inogona kuve nekugona kuderedza kuzvimba uye kudzivirira kubva mukukuvadzwa kweoxidative, izvo zvingave zvine chekuita nekutsigira hutano hwese uye kugara zvakanaka.
Parizvino, evodiamine inonyanya kuwanikwa sechikafu chekuwedzera, iyo ine nhevedzano yehutano hunobatsira kumuviri wemunhu.
Evodiamine yakawanikwa ichiita mhedzisiro yayo kuburikidza neakawanda mamorekuru nzira. Imwe yenzira dzakakosha dzechiito che evodiamine kugona kwayo kumisa kwenguva pfupi receptor inogona kuva vanilloid 1 (TRPV1) chiteshi. TRPV1 inogamuchira inobatanidzwa mukurwadziwa uye kunzwa kwekupisa, uye kushandiswa kwayo ne evodiamine kwakaratidzwa kuti iite thermogenesis uye kuwedzera kushandiswa kwesimba. Iyi thermogenic mhedzisiro ye evodiamine inogona kubatsira kune yayo inopesana nekufutisa zvivakwa, zvichiita kuti ive chinangwa chekuvandudza uremu kupindira.
Pamusoro pemigumisiro yayo paTRPV1, evodiamine yakawanikwa ichigadzirisa zvimwe zvinangwa zvema molecular, kusanganisira adenosine monophosphate-activated protein kinase (AMPK) uye peroxisome proliferator-activated receptor gamma (PPARγ). AMPK ndiye mutongi anokosha we cellular energy homeostasis, uye kushandiswa kwayo ne evodiamine kunokurudzira kutorwa kweglucose uye fatty acid oxidation, nokudaro kuvandudza insulin senitivity uye hutano hwemagetsi. Kune rumwe rutivi, kushandiswa kwePPARγ ne evodiamine kunogona kudzora kutaura kwemajini anobatanidzwa mu lipid metabolism uye adipogenesis, zvichiwedzera kupa kune iyo inopesana nekufutisa.
Uyezve, evodiamine yakaratidzwa kuratidza anti-inflammatory properties nekudzivisa nyukireya factor kappa B (NF-κB) chiratidzo. NF-κB ndiyo inonyanya kugadzirisa mhinduro dzekuputika, uye kukanganiswa kwayo kunobatanidzwa nemhando dzakasiyana-siyana dzezvirwere zvisingaperi. Nekudzivisa NF-κB activation, evodiamine inogona kuderedza kugadzirwa kwevamiririri ve-pro-inflammatory uye kuderedza kuputika, zvichiratidza kuti inogona kuita basa rekurapa mukurapa zvirwere zvinopisa.
Uyezve, iyo anticancer mhedzisiro ye evodiamine inokonzerwa nekugona kwayo kukonzeresa apoptosis uye kumisa kuwanda muakasiyana kenza cell mitsara. Izvi zvinofungidzirwa kuti zviitike kuburikidza nekugadzirisa nzira dzakawanda dzechiratidzo dzinobatanidzwa mukupona kwesero uye kukura, kusanganisira mitogen-activated protein kinase (MAPK) uye phosphoinositide 3-kinase (PI3K) / Akt nzira. Mukuwedzera, evodiamine yakaratidzwa kuvharidzira kutaura kwematrix metalloproteinases (MMPs), ma enzymes anobatanidzwa mukuputika kwebundu uye metastasis.
1.Inobatsira kuderedza uremu uye kuderedza metabolism
Kiyi yekubatsira evodiamine nekurasikirwa nekurema kuri kuwedzera thermogenesis mumuviri. Thermogenesis ndiyo nzira iyo muviri unogadzira kupisa uye kupisa macalorie. Nekukurudzira thermogenesis, evodiamine inogona kubatsira kusimbisa metabolism uye kukurudzira kupisa kwemafuta. Izvi zvinoreva kuti iwe unopisa macalorie akawanda mukati mezuva rese, kunyangwe pakuzorora, zvichitungamira kukuwedzera uremu nekufamba kwenguva.
Pamusoro pemigumisiro yayo pane thermogenesis, evodiamine inogonawo kuva nemigumisiro pamafuta metabolism. Kutsvakurudza kunoratidza kuti evodiamine inogona kubatsira kuwedzera kuparara kwemafuta uye kudzivisa kuumbwa kwemasero matsva emafuta. Izvi zvinoreva kuti kwete chete zvinokubatsira kupisa zvitoro zvemafuta zviripo, zvinodzivirirawo kuunganidzwa kwemafuta matsva, zvichiita kuti zvive nyore kuchengetedza uremu munguva refu.
Uyezve, evodiamine yakaratidzwa kuva nemigumisiro yekuda kudya-kudzvinyirira. Nekuderedza nzara uye nekuwedzera manzwiro ekuzara, evodiamine inogona kukubatsira kuti udye mashoma macalorie, zvichiita kuti zvive nyore kuomerera pakudya kwako uye kuzadzisa zvinangwa zvako zvekurasikirwa uremu. Uyezve, imwe tsvakurudzo inoratidza kuti evodiamine inogonawo kuva ne-anti-inflammatory uye antioxidant properties, iyo inogona kubatsira hutano hwese uye hutano panguva yekurasikirwa.
2.Inobatsira kuderedza kuzvimba
Evodiamine inotorwa kubva kumuchero weEvodia rutaecarpa chirimwa, icho chave chichishandiswa mumishonga yechivanhu yekuChina kurapa zvirwere zvakasiyana kwemazana emakore. Tsvagiridzo ye evodiamine inoratidza kuti inotadzisa kugadzirwa kwemamorekuru ekuputika mumuviri, senge cytokines uye prostaglandin. Izvi zvinobatsira kuderedza huwandu hwehuwandu hwekuzvimba mumuviri, nekudaro kuderedza marwadzo uye zvimwe zviratidzo zvine chekuita nekuzvimba kusingaperi.
Chidzidzo chakabudiswa muJournal of Ethnopharmacology chakawana kuti evodiamine yaive neyakakura anti-inflammatory mhedzisiro mumakonzo ane kuzvimba kwakakonzera. Vatsvakurudzi vakagumisa kuti evodiamine inogona kuva mushonga unobatsira wezvirwere zvinopisa. Imwe ongororo mujenari Phytomedicine yakawana kuti evodiamine yaive ine masimba ekurwisa-kuzvimba mumasero tsika, zvichiratidza kuti inogona zvakare kuve mushonga unoshanda wekuzvimba muvanhu.
3.Inobatsira hutano hwemwoyo
Evodiamine yakaratidza kuti ine vasodilatory properties, zvinoreva kuti inogona kubatsira kuzorora uye kuwedzera mitsipa yeropa, nokudaro kuvandudza kubuda kweropa. Izvi zvinonyanya kubatsira kune vanhu vane high blood pressure, sezvo inogona kubatsira kuderedza basa remwoyo uye kuderedza dambudziko rematambudziko akadai sekurohwa kana chirwere chemoyo.
Pamusoro pezvo, evodiamine yakadzidzwa nekuda kwekugona kwayo kuderedza kuzvimba uye oxidative kusagadzikana, zvese zviri zviviri zvakabatana nekukura kwechirwere chemoyo. Nekudzikisa njodzi idzi, evodiamine inogona kubatsira kudzivirira moyo nemidziyo yeropa kubva mukukuvadzwa uye kusashanda. Evodiamine yakawanikwa iine antiplatelet uye antithrombotic madhara, zvinoreva kuti inogona kubatsira kudzivirira kuvhara ropa kubva pakuumba. Kuvhara ropa kunogona kukanganisa kuyerera kweropa uye kutungamirira kuzviitiko zvakakomba zvemwoyo, saka kukwanisa kwe evodiamine kurambidza kuumbwa kwevhavha kunogona kuva nemigumisiro inokosha pahutano hwemwoyo.
4.Kutsigira Gastrointestinal Health
Tsvagiridzo inoratidza kuti evodiamine inogona kuve nezvakawanda zvinobatsira pagastrointestinal system. Iine anti-inflammatory uye antioxidant properties iyo inobatsira kuchengetedza dumbu uye intestinal lining kubva pakukuvadzwa kunokonzerwa nemahara radicals uye kuzvimba. Mukuwedzera, evodiamine yakaratidzwa kuva nemishonga inorwisa mabhakitiriya uye inogona kubatsira kukurudzira hutano hwehutano hwehutachiona hwehutachiona uye kuderedza ngozi yehutachiona hwehutachiwana.
Mukuwedzera, evodiamine yakawanikwa iine anti-ulcer properties, inobatsira kuderedza dambudziko remaronda emudumbu uye mamwe matambudziko emudumbu. Nekusimudzira kutendeseka kwemucosal lining uye inhibiting yakawandisa acid secretion, evodiamine inogona kubatsira kuchengetedza dumbu nematumbu kubva mukukuvadzwa uye kutsamwa.
5.Zvimwe zvikomborero zvehutano
Evodiamine ine simba rekugadzirisa mazinga ehuga. Kuwanda kweshuga muropa kunogona kutungamirira kuhutano hwakasiyana-siyana, kusanganisira chirwere cheshuga uye chirwere chemwoyo. Tsvagiridzo inoratidza kuti evodiamine inogona kubatsira kuvandudza insulin senitivity uye kudzora mazinga eshuga yeropa, zvichiita kuti ive chishandiso chakakosha kune chero munhu anotarisa kuchengetedza hutano hwehuga hweropa.
Pamusoro pekugona kwayo kugadzirisa shuga yeropa, evodiamine yakawanikwawo kuderedza cholesterol. High cholesterol mazinga anowedzera njodzi yechirwere chemoyo uye sitiroko, saka kutsvaga nzira dzechisikigo dzekudzikisa cholesterol yako kwakakosha kuchengetedza hutano hwako hwese. Evodiamine yakaratidzwa kuderedza mazinga eLDL cholesterol (yakaipa "cholesterol") ichiwedzera mazinga eHDL cholesterol (inonziwo "yakanaka" cholesterol).
Uyezve, evodiamine yakawanikwa ichiwedzera huwandu hwesimba. Munyika yanhasi inomhanya-mhanya, vanhu vakawanda vanonetseka nekushaya simba uye kuneta. Evodiamine yakaratidzwa kuwedzera metabolism uye kushandiswa kwesimba, nekudaro kuwedzera kwesimba mazinga. Izvi zvinonyanya kubatsira kune vatambi kana chero munhu anoda kuvandudza simba ravo rose uye kusimba.
Kana uchienzanisa evodiamine supplements, chinhu chekutanga kufunga ndiko kunobva evodiamine. Zvakakosha kusarudza kuwedzera kunoshandisa yakakwirira-mhando, yakachena evodiamine inotorwa kubva kune inoremekedzwa sosi. Tarisa zvigadzirwa zvakaedzwa-wechitatu uye uine chitupa chekuongorora kuti uve nechokwadi chekuchena uye potency.
Chimwe chinhu chakakosha chekufunga nezve dosage ye evodiamine mukuwedzera. Iyo yakakurudzirwa dosage ye evodiamine inogona kusiyana zvichienderana nemunhu uye yavo chaiyo yehutano zvinangwa. Zvimwe zvekuwedzera zvinogona kunge zvine yakakwira kana yakaderera kuwanda kwe evodiamine, saka zvakakosha kusarudza imwe inoenderana nezvido zvako nezvaunoda.
Kuwedzera kune evodiamine zvirimo, zvakakosha kuti utarise zvimwe zvinongedzo mukuwedzera kwako. Mamwe evodiamine anowedzera anogona kunge aine zvimwe zvinongedzo, senge dema mhiripiri inobvisa kana green tea inobvisa.
Uyezve, chimiro chekuwedzera ndechimwe chinhu chakakosha kufunga. Evodiamine supplements inowanikwa nenzira dzakasiyana-siyana, kusanganisira capsules, powders, uye tinctures. Sarudza chimiro chiri nyore uye chiri nyore kuisa muhupenyu hwako hwezuva nezuva. Semuenzaniso, kana uine dambudziko rekumedza mapiritsi, poda inogona kunge iri sarudzo iri nani kwauri.
Izvo zvakakoshawo kufunga nezvemhando kana uchisarudza evodiamine yekuwedzera. Tsvaga mugadziri weruzhinji ane nhoroondo yekugadzira yepamusoro-mhando yekuwedzera uye yakanaka ongororo yevatengi. Tsvakurudza maitiro ekugadzira mhando uye matanho ekudzora mhando kuti uve nechokwadi chekuti uri kuwana chigadzirwa chakachengeteka uye chakavimbika.
Chekupedzisira, kana uchisarudza evodiamine yekuwedzera, funga nezvehutano hwako pachako zvinangwa uye chero hutano hunonetsa. Vamwe vanhu vangave vachifarira evodiamine yekudzora uremu, nepo vamwe vangangoda kutsigira hutano hwekudya kana hutano hwese. Zvakare, bvunza nyanzvi yezvehutano usati watanga chero chirongwa chitsva chekuwedzera, kunyanya kana uine hutano huripo kana uri kutora mishonga.
Suzhou Myland Pharm & Nutrition Inc. yave ichiita bhizinesi rekuwedzera chikafu kubva muna 1992. Ndiyo kambani yekutanga muChina kugadzira nekutengesa mhodzi dzemazambiringa.
Iine makore makumi matatu echiitiko uye ichitungamirwa nehunyanzvi hwepamusoro uye yakagadziridzwa zvakanyanya R&D zano, kambani yakagadzira mhando yezvigadzirwa zvemakwikwi uye ikava yekuvandudza hupenyu hwesainzi yekuwedzera, yetsika synthesis uye kambani yekugadzira masevhisi.
Pamusoro pezvo, kambani iyi zvakare FDA-yakanyoreswa mugadziri, inovimbisa hutano hwevanhu nemhando yakagadzikana uye kukura kwakasimba. Zviwanikwa zvekambani zveR&D uye zvivakwa zvekugadzira uye zviridzwa zvekuongorora ndezvemazuva ano uye zvinoshanda, uye zvinokwanisa kugadzira makemikari pamilligram kusvika toni sikero zvichiteerana neISO 9001 zviyero uye GMP maitiro ekugadzira.
Mubvunzo: Chii chinonzi evodiamine?
A: Evodiamine musanganiswa wechisikigo unowanikwa mumuchero weEvodia rutaecarpa chirimwa, Wagara uchishandiswa mumishonga yechivanhu yekuChina kwemazana emakore uye unozivikanwa nekugona kubatsira pautano.
Mubvunzo: Ndezvipi zvingave zvinobatsira zve evodiamine supplements?
A: Evodiamine zvinowedzera zvinotendwa kuti zvine hutano hwakasiyana-siyana hunogona kubatsira, kusanganisira kutsigirwa kwekuremera, metabolism, uye hutano hwese. Uyezve, vanogona kunge vane anti-inflammatory uye antioxidant properties.
Mubvunzo: Ndinofanira kubatanidza sei evodiamine zvinowedzera muhutano hwangu uye chirongwa chekudya?
A: Usati waisa chero chitsva chekuwedzera muhutano hwako uye chirongwa chekudya, zvakakosha kubvunza nyanzvi yehutano. Vanogona kukubatsira kuona muyero wakakodzera uye kuongorora chero kungangoitika kusangana nemimwe mishonga kana ma supplements aungave uchitora.
Mubvunzo: Pane here zvingangoitika zveevodiamine supplements?
A: Kunyange zvazvo evodiamine supplements inowanzoonekwa yakachengeteka kuvanhu vakawanda kana yakatorwa mumatareji akakodzera, vamwe vanhu vanogona kusangana nemigumisiro yakadai sekugumburwa kwekudya kana kutsamwa. Zvakakosha kutevera dosi yakakurudzirwa uye kutarisa mhinduro yemuviri wako kune kuwedzera.
Mubvunzo: Pane here matanho ekutarisisa kana uchitora evodiamine supplements?
A: Kana iwe uri nepamuviri, mukoti, kana uine chero mamiriro ezvinhu ehutano, zvakakosha kutaura nenyanzvi yezvehutano usati watora evodiamine supplements. Pamusoro pezvo, zvakakosha kutenga ma supplements kubva kune ane mukurumbira sosi kuve nechokwadi chemhando uye chengetedzo.
Disclaimer: Ichi chinyorwa ndecheruzivo rwese chete uye hachifanirwe kutorwa sechero zano rekurapa. Imwe yeruzivo rweblog post runobva kuInternet uye haina hunyanzvi. Iyi webhusaiti inongova nebasa rekugadzirisa, kufomatidza uye kugadzirisa zvinyorwa. Chinangwa chekuendesa rumwe ruzivo hachirevi kuti unobvumirana nemaonero ayo kana kusimbisa uchokwadi hwezvirimo. Nguva dzose bvunza nyanzvi yezvehutano usati washandisa chero chekuwedzera kana kuita shanduko kuhutano hwako hwehutano.
Nguva yekutumira: Feb-02-2024
