Choline alfoscerate, inozivikanwawo seAlpha-GPC, yave yakakurumbira cognitive-enhancing supplement. Asi nezvakawanda zvingasarudzwa kunze uko, unosarudza sei yakanakisa choline alfoscerate poda yekuwedzera? Iyo yakanakisa choline alfoscerate poda yekuwedzera ye2024 inoda kunyatsotariswa kwekuchena, dosi, mukurumbira wemhando, mutengo, uye zvimwe zvinongedzo. Nekufunga zvinhu izvi, unogona kuwana yemhando yepamusoro yekuwedzera inotsigira hutano hwako hwekuziva uye inokubatsira kuzadzisa zvinangwa zvehutano hwako. Usati watanga chero chitsva chekuwedzera, gara uchibvunza nyanzvi yezvehutano kuti uone kuti isarudzo yakakunakira iwe.
Alpha GPCndiyo chidimbu che alpha-glycerophosphocholine, inozivikanwawo se glycerophosphocholine. Iyo phospholipid ine choline uye chimwe chezvikamu zvikuru zvesero membranes. Iine high choline content. Inenge 41% yehuremu hweAlpha GPC ndeye choline. Choline inoshandiswa mukusaina sero muuropi uye tsinga dzinotyisa, uye Alpha GPC yekuwedzera inowanzosanganiswa nemamwe makomisheni anonzi nootropics. Nootropics ikirasi yemishonga uye/kana ma supplements anobatsira kutsigira nekusimudzira kugona kwekuziva.
Chii chinonzi choline?
Muviri unogadzira alpha GPC kubva kucholine. Choline chinhu chakakosha chekudya chinodiwa nemuviri kune hutano hwakakwana. Kunyange zvazvo choline isiri vhitamini kana mineral, inowanzoenderana neB mavhitaminzi nekuda kwemaitiro akafanana emuviri mumuviri.
Choline inodiwa kune yakajairika metabolism, inoshanda semethyl donor, uye inotoita basa rakakosha mukugadzirwa kwemamwe ma neurotransmitters akadai seacetylcholine.
Choline chinhu chakakosha chekudya chinowanikwa sechisikigo mumukaka wemuzamu wevanhu uye chinowedzerwa kune inotengeswa mucheche formula.
Kunyange zvazvo muviri uchibudisa choline muchiropa, hazvina kukwana kutsigira zvinodiwa nemuviri. Kusakwana kugadzirwa kwecholine mumuviri zvinoreva kuti choline inoda kuwanikwa kubva mukudya. Kushaikwa kwecholine kunogona kuitika kana kudya choline kudya kusina kukwana.
Zvidzidzo zvakabatanidza kushomeka kwecholine kune atherosclerosis kana kuoma kwetsinga, chirwere chechiropa, uye kunyange neurological kusagadzikana. Uyezve, zvinofungidzirwa kuti vanhu vakawanda havadyi zvokudya zvakakwana muzvokudya zvavo.
Kunyange zvazvo choline inowanikwa zvakasikwa muzvokudya zvakadai semombe, mazai, soya, quinoa, uye mbatatisi tsvuku, kuwedzera nealpha GPC kunogona kubatsira kukurumidza kuwedzera mazinga echoline mumuviri.
Glycerylphosphocholine inoshandiswawo zvakanyanya mukurapa uye biochemical research pamwe nemishonga yekushandisa.
1. Kuwanikwa uye tsvakiridzo yekutanga: Glycerylphosphocholine yakatanga kuwanikwa neGerman biochemist Theodor Nicolas Lyman mukutanga kwezana ramakore rechi 19. Akatanga abvisa chinhu kubva pajoko rezai, asi magadzirirwo awo uye kushanda kwawo zvakanga zvisati zvanyatsonzwisiswa.
2. Kuzivikanwa kwemaitiro: Pakutanga kwezana remakore rechi20, masayendisiti akatanga kudzidza maitiro e glycerophosphocholine zvakanyanya, uye pakupedzisira akafunga kuti inosanganisira glycerol, phosphate, choline uye maviri emafuta acid akasara. Izvi zvikamu zvakabatanidzwa nenzira dzakananga mukati memorekuru kuita phospholipid mamorekuru.
3. Biology mabasa: Zvishoma nezvishoma zvinozivikanwa kuti glycerophosphocholine inoita basa rinokosha mubhayoloji, kunyanya mukuvaka nekuchengetedza maseru membranes. Izvo zvakakosha kune fluidity uye kugadzikana kwesero membranes uye zvine mhedzisiro pakusaina, intercellular kutaurirana, uye synthesis yecholine.
Kuratidzira kwesero
Miviri yedu inoita mabasa akati wandei padanho remaserura mazuva ese tisingazvizivi. Zvakadai sokuyerera kweropa uye kurova kwehana. Mamiriyoni emasero anotaurirana kuti ape muviri kukwanisa kupedza mabasa aya uye kushanda zvakanaka. Uku kutaurirana pakati pemasero kunonzi "cell signing". Mamorekuru akawanda enhume anotumira masaini pakati pemasero senge nharembozha.
Pese masero paanotaurirana, simba remagetsi rinokonzeresa kuburitswa kwemaurotransmitters munzvimbo inonzi synapse. MaNeurotransmitters anofamba kubva kune synapses uye anosunga kune zvinogamuchirwa pane dendrites, iyo inogamuchira uye inogadzirisa ruzivo rwavanogamuchira.
PGC-1α inoratidzirwa pamazinga akakwirira mumitochondria uye nzvimbo dzakananga dzekushanda metabolism. Izvi zvinosanganisira uropi, chiropa, pancreas, skeletal tsandanyama, mwoyo, digestive system uye nervous system.
Zvinozivikanwa kuti panguva yekuchembera, cellular mitochondria ndiyo yakanyanya kukuvadzwa organelles. Naizvozvo, clearance uye mitochondrial biogenesis (kugadzira mitochondria itsva) yakakosha pakuenzanisa simba remetabolism. PGC-1α inoita basa rakakosha mukurwisa kukwegura. Tsvagiridzo inoratidza kuti PGC-1a inodzivirira tsandanyama atrophy nekudzora autophagy (kuchenesa masero). Zvidzidzo zvemhuka zvinoratidza kuti kuwedzera kwePGC-1α kunogona kuvandudza mamiriro akasiyana emhasuru. Chinangwa chedu ndechekubatsira kuwedzera mazinga ePGC-1α.
Muna 2014, vatsvakurudzi vakadzidza mhuka dzakabudisa yakawandisa PGC-1α mumhasuru dzavo fiber uye zvidzoreso izvo zvisina kubudisa yakawandisa PGC-1α. Mukutsvakurudza, mhuka dzinosangana nepamusoro-soro mamiriro ezvinhu. Isu tinoziva kuti kushungurudzika kazhinji kunogona kuwedzera njodzi yekuora mwoyo. Zvakaonekwa kuti mhuka dzine mazinga akakwirira ePGC-1α dzaive dzakasimba uye dzakakwanisa kurarama nezviratidzo zvekuora mwoyo kupfuura avo vane mazinga akaderera ePGC-1α. Naizvozvo, chidzidzo ichi chinoratidza kuti activating PGC-1α inogona kuvandudza mafungiro.
PGC-1α inewo imwe yekudzivirira maitiro pamamhasuru. Myoblasts imhando yemhasuru sero. Chidzidzo chinoratidza kukosha kwePGC-1α-mediated nzira uye basa rayo muskeletal muscle atrophy. PGC-1α inokurudzira mitochondrial biogenesis muchikamu nekusimudzira NRF-1 uye 2. Zvidzidzo zvakaratidza kuti mutsara-yakananga PGC-1α kunyanya kunetseka kunokosha kune skeletal muscle atrophy (kuderedza inzwi uye kushaya simba). Kana chiitiko chePGC-1α mitochondrial biological pathway chakawedzerwa, kukuvara kweoxidative kunoderedzwa. Nokudaro, PGC-1α inofungidzirwa kuti inobata basa rekudzivirira mukuderedza skeletal muscle degeneration.
Nrf2 nzira yekusaina
(Nrf-2) chinhu chinodzora chinobatsira kudzivirira kubva kuma cell oxidants anokuvadza kumasero. Inogadzirisa kutaura kweanopfuura mazana matatu ekunangwa majini kubatsira metabolism, kuwedzera antioxidant kudzivirira uye kubatsira kupindura kwemuviri kuzvimba. Zvidzidzo zverabhoritari zvinoratidza kuti activating Nrf-2 inogona kuwedzera hupenyu nekudzivisa oxidation.
Alpha GPC inowedzera acetylcholine mazinga muuropi. Acetylcholine inodiwa pakurangarira uye kugona basa uye kusaina pakati peeuroni munzvimbo dzakasiyana dzehuropi. Mazai, hove, nzungu, cauliflower, broccoli uye zvinovaka muviri zvinovaka muviri zvakapfuma zvecholine.
Kubvaalpha GPCinogadzirwa mumuviri, inogadziriswa kuphosphatidylcholine. Phosphatidylcholine, chikamu chikuru chelecithin, inowanikwa mumaseru ese emuviri uye inoshandiswa nenzira dzakasiyana siyana kutsigira muviri, kusanganisira hutano hwechiropa, hutano hwegallbladder, metabolism, uye kugadzirwa kweiyo neurotransmitter acetylcholine.
Acetylcholine ikemikari messenger inobvumira masero etsinga kuti ataurirane nemamwe masero etsinga, masero emhasuru, uye kunyange matinji. Acetylcholine inodiwa pamabasa mazhinji, kusanganisira kudzora kurova kwemoyo, kuchengetedza BP, uye kuronga kufamba mukati mematumbo.
Nepo kushomeka kweacetylcholine kuchiwanzobatanidzwa nemyasthenia gravis, mazinga akaderera eurotransmitter akabatanidzwawo nekusarangarira zvakanaka, matambudziko ekudzidza, kuderera kwetsandanyama toni, dementia, uye chirwere cheAlzheimer.
Tsvagiridzo inoratidza kuti alpha-GPC inobatsira kuwedzera acetylcholine muuropi nekuti inokurumidza kunyura uye inoyambuka zviri nyore chipingamupinyi cheropa-uropi.
Kugona uku kunopa alpha GPC mamwe akasarudzika ehutano mabhenefiti, akadai sekubatsira kusimudzira ndangariro, kuwedzera cognition, kunatsiridza kuita kwemitambo, uye kuwedzera kukura kwehomoni secretion.
1. Alpha GPC uye ndangariro zvinowedzera
Tsvagiridzo inoratidza kuti alpha GPC inogona kubatsira kutsigira ndangariro basa uye kuumbwa nekuda kwehukama hwayo neacetylcholine. Sezvo acetylcholine yakakosha pakuumbwa kwendangariro nekuchengetedza, alpha GPC inogona kubatsira kukurudzira kuumbwa kwendangariro.
Chidzidzo chemhuka chinosanganisira makonzo chakawana kuti alpha GPC yekuwedzera yakabatsira kusimudzira ndangariro uku ichidzivirira huropi kubva kune inokuvadza yekushushikana.
Chimwe chidzidzo chemhuka chakawana kuti kuwedzera nealpha GPC kwakabatsira kuvandudza masero ehuropi uye kudzivirira uropi huzhinji uye kufa mushure mekubatwa nepfari.
Muvanhu, zvidzidzo zvakati wandei zvakaitwa kuongorora alpha GPC yekuwedzera pakurangarira uye kugona kwekuziva izwi muvanhu vane zera-kurasikirwa kwekunzwa.
Zvisinei, chimwe chidzidzo chinosanganisira vatori vechikamu 57 vane makore 65 kusvika ku85 vakawana kuti kuwedzera nealpha GPC kwakavandudza zvikuru mazita ekuzivikanwa kwemazwi pamusoro pemwedzi ye11. Boka rekutonga iro risina kugamuchira alpha GPC raive nekuita kwekuziva kwemazwi kwakashata. Pamusoro pezvo, mashoma mhedzisiro zvakataurwa muboka vachishandisa alpha GPC panguva yekudzidza.
Nepo alpha GPC inogona kubatsira kusimudzira ndangariro, tsvagiridzo inoratidza kuti inogona kubatsirawo kuvandudza kugona kwekuziva.
2. Alpha GPC uye kugadzirisa kwekuziva
Tsvagiridzo inoratidza kuti alpha GPC inogona kubatsira kuvandudza nekusimudzira kugona kwekuziva kupfuura kubereka kwendangariro.
Semuenzaniso, imwe kaviri-mapofu, randomized, placebo-inodzorwa kudzidza yaisanganisira vanopfuura 260 varume nevakadzi vatori vechikamu vane makore makumi matanhatu kusvika makumi masere vakaonekwa vaine chirwere cheAlzheimer chakapfava kusvika pakati. Vatori vechikamu vakatora alpha GPC kana placebo katatu pazuva kwemazuva 180.
Pamazuva e90, chidzidzo chacho chakawana kuvandudzwa kwakakosha mukushanda kwekuziva muboka reAlpha GPC. Pakupera kwechidzidzo, boka reAlpha GPC rakaratidza kuvandudzwa kwese kwekuita kwekuziva asi kuderera kweGlobal Deterioration Scale (GDS) zvibodzwa. Kusiyana neizvi, zvibodzwa muboka replacebo zvakaramba zvakafanana kana kuwedzera. GDS bvunzo yekuongorora iyo inobatsira vatapi vehutano kuti vaone kuti munhu ane dementia.
Imwe ongororo yakawana kuti alpha GPC yekuwedzera inogona kubatsira kunonoka kuderera kwekuziva muvakuru vakuru vane hypertension. Chidzidzo chacho chaisanganisira vatori vechikamu 51 vakwegura vakakamurwa kuva mapoka maviri. Rimwe boka rakagamuchira alpha GPC supplements, nepo rimwe boka harina. Pakutevera kwemwedzi we6, chidzidzo chakawana kuvandudzwa kwakakosha mukugona kwekuziva muboka reAlpha GPC. Zvidzidzo zvinoratidza kuti alpha-GPC inonatsiridza kuvimbika kwemudziyo weropa uye kukura, zvichibatsira kuwedzera kupfava kwehuropi nekuvandudza kugona kwekuziva.
Nepo alpha GPC inogona kubatsira kusimudzira kugona kwekuziva, tsvakiridzo inoratidza kuti inogona kubatsira kuvandudza kuita kwemitambo.
3. Alpha GPC uye kuvandudza kuita kwemitambo
Kunyange zvazvo tsvakurudzo inoratidza kuti alpha GPC inogona kubatsira cognition, tsvakurudzo inoratidzawo kuti nootropic iyi inoshamisa inogona kuva nehuwandu hwezvibatsiro zvemuviri.
Tsvagiridzo inoratidza kuti kuwedzera nealpha GPC kunogona kubatsira kuvandudza kuita kwemitambo uye simba. Semuyenzaniso, kaviri-bofu placebo-inodzorwa kudzidza yaisanganisira gumi nevatatu vekoreji varume vanotora alpha GPC kwemazuva matanhatu. Vatori vechikamu vakapedza akati wandei maekisesaizi, kusanganisira isometric maekisesaizi ekumusoro nepasi muviri. Tsvagiridzo yakawana kuti alpha GPC yekuwedzera inovandudza isometric simba kupfuura placebo.
Imwezve yakapetwa kaviri-mapofu, randomized, placebo-inodzorwa chidzidzo chaisanganisira 14 varume vekoreji vatambi venhabvu vane makore 20 kusvika 21 makore. Vatori vechikamu vakatora alpha GPC supplements 1 awa vasati vaita nhevedzano yezviekisesaizi, kusanganisira kusvetuka kwakatwasuka, isometric kurovedza, uye tsandanyama kudzvanya. Tsvagiridzo yakawana kuti kuwedzera nealpha-GPC usati waita maekisesaizi kunogona kubatsira kuwedzera kumhanya kwekusimudza uremu. Tsvagiridzo yakawana zvakare kuti kuwedzera nealpha GPC kunogona kubatsira kuderedza kuneta kwakabatana nekurovedza muviri.
Tsvagiridzo inoratidza kuti alpha GPC haingobatsiri kuvandudza kuita kwemitambo asi inogona kubatsira kuwedzera kukura kwekugadzirwa kwehomoni.
4. Alpha GPC uye yakawedzera kukura kwehomoni secretion
Hormone yekukura kwevanhu, kana HGH kwenguva pfupi, ihomoni inogadzirwa nepituitary gland muuropi. HGH inodiwa kune hutano hwese muvana nevakuru. Muvana, HGH inokonzera kuwedzera urefu nekusimudzira kukura kwemapfupa uye cartilage.
Muvanhu vakuru, HGH inogona kubatsira kusimudzira hutano hwemapfupa nekuwedzera kuwanda kwemapfupa uye kutsigira mhasuru dzine hutano nekusimudzira kukura kwemhasuru. HGH inozivikanwa zvakare kuvandudza kuita kwemitambo, asi kushandiswa kwakananga kweHGH kuburikidza nejekiseni kwakarambidzwa mumitambo yakawanda.
Nekuti kugadzirwa kweHGH kunotanga kudzikira mukati mehupenyu hwepakati, izvi zvinogona kukonzera kuunganidzwa kwemafuta emudumbu, kurasikirwa kwemhasuru, brittle mapfupa, hutano husina kunaka hwemoyo, uye kunyangwe njodzi yekufa.
Tsvagiridzo inoratidza kuti alpha GPC yekuwedzera inogona kubatsira kukurudzira kuwedzera kukura kwehomoni secretion, kunyangwe muvakuru vepakati.
A kaviri-mapofu, randomized, placebo-controlled controlled study yaisanganisira varume ve7 vane makore 30 kusvika kumakore 37 avo vakaita kusimudza uremu nekudzidzira kudzidzira mushure mekuwedzera nealpha GPC. Zvidzidzo zvakawana kuti kuwedzera alpha GPC kusati kwaita uremu kudzidziswa uye kuramba kurovedza muviri kunowedzera kukura kwehomoni secretion nekuwanda kwe44-fold, pane kungopeta 2.6.
Kuwedzera kugadzirwa kweHGH mukati mehupenyu hwepakati kunobatanidzwa nekuderedzwa kwemafuta emuviri, hukuru hwemhasuru kuwanda, uye nekuvandudza kugona kwekuita.
Alpha GPCiri nyore inowanikwa choline supplement iyo inogona kubatsira kuvandudza chiyeuchidzo, kuwedzera cognition, kuwedzera chaiyo-yenyika kuita, uye kunyange kuwedzera kukura kwehomoni kugadzirwa uye kuvanzika.
Kubatanidza alpha GPC muhutano hwemazuva ese hunogona kupa hupenyu hwese kuhuropi nemuviri uye kukurudzira hutano hwese kwemakore anotevera.
Nzvimbo dzekushandisa:
1. Kurapa kwekurapa: Choline Alfoscerate inoshandiswa mukurapa kurapa chiropa chemafuta, zvimwe zvirwere zvetsinga, zvirwere zvemwoyo, nezvimwewo. Haisi chete inopa huwandu hwepamusoro hwecholine hunodiwa nemasero europi uye masero emagetsi, inodzivirirawo masero avo masvingo. Varwere vane chirwere cheAlzheimer vanonyanya kuve nekudzikira kwendangariro nekuziva basa, uye vanoperekedzwa neakasiyana matambudziko, akadai sekuderera kwekufamba, kusagadzikana kwetsinga uye kumwe kukanganisa kushanda. Clinical pharmacological test results uye makiriniki ekuedza akasimbisa kuti glycerophosphocholine inobatsira zvikuru pakuziva kugona uye ndangariro kushanda kwehuropi. Iyo ine zvakare inogona kushandiswa mumasisitimu ekutumira zvinodhaka, ichibatsira mishonga kuyambuka maseru membranes zvakanyanya.
2.Cosmetic: Choline Alfoscerate inowanzoshandiswa mumajekiseni ekuzora kuti ivandudze kuonekwa kweganda.
1.Piracetam
Piracetam ndeimwe yekare uye yakakurumbira nootropics. Iyo ndeyemhuri yedzinza uye inowanzoshandiswa kusimudzira kugona kwekuziva uye ndangariro.
Mechanism: Piracetam inogadzirisa neurotransmitter acetylcholine uye inowedzera neuronal kutaurirana.
Benefits: Inonyanya kushandiswa kuvandudza chiyeuchidzo, kugona kudzidza uye kuisa pfungwa.
Cons: Vamwe vashandisi vanotaura kuti mhedzisiro yePiracetam haina kujeka uye ingangoda kuiswa pamwe nemamwe ma nootropics kuti vawane mabhenefiti anooneka.
Kuenzanisa: Nepo zvese Alpha GPC nePiracetam zvichivandudza mashandiro ekuziva, Alpha GPC ine mhedzisiro yakanangana neacetylcholine mazinga uye inogona kupa mamwe mabhenefiti akataurwa ekurangarira nekudzidza.
2. Noopept
Noopept ine simba nootropic drug inozivikanwa nekuziva kwayo-enhancing properties. Inowanzofananidzwa nepiracetam asi inonzi yakasimba.
MECHANISM: Noopept inowedzera mazinga europi-derived neurotrophic factor (BDNF) uye nerve yekukura factor (NGF), inotsigira hutano hwehuropi uye basa rekuziva.
Benefits: Inoshandiswa kuvandudza ndangariro, kudzidza, uye neuroprotection.
Kukanganisa: Noopept inogona kukonzera mimwe migumisiro, yakadai semusoro uye kutsamwa.
Kuenzanisa: Noopept naAlpha GPC vose vane migumisiro yekuziva-inowedzera, asi Noopept's mechanism inosanganisira neurotrophic factor, asi Alpha GPC inotarisa pane acetylcholine. Kune avo vanonyanya kutarisa kuwedzera acetylcholine mazinga, Alpha GPC inogona kunge iri nani.
3. L-Theanine
L-theanine iamino acid inowanikwa mutii inozivikanwa nekudzikamisa mhedzisiro uye kugona kwekusimudzira kutarisa pasina kukonzera hope.
Mechanism: L-theanine inowedzera mazinga eGABA, serotonin uye dopamine, kukurudzira kuzorora nekuvandudza mafungiro.
Benefits: Inoshandiswa kuderedza kuzvidya mwoyo, kunatsiridza kuisa pfungwa pachinhu chimwe, uye kugadzirisa mafungiro.
Cons: L-theanine inowanzotenderwa zvakanaka, asi mhedzisiro yaro yakanyanya kujeka kupfuura mamwe nootropics.
Kuenzanisa: L-Theanine uye Alpha GPC vane kushandiswa kwakasiyana. Alpha GPC inonyanya kutarisana nekusimudzira kugona kwekuziva kuburikidza neacetylcholine, nepo L-theanine inokodzera zvirinani kuzorora nekuvandudza mafungiro. Zvinopindirana kana zvichishandiswa pamwechete.
4. Modafinil
Modafinil inomuka-inokurudzira mishonga inowanzoshandiswa kurapa zvirwere zvekurara. Iyo inozivikanwa zvakare seyekuziva yekusimudzira.
Mechanism: Modafinil inobata neurotransmitters dzakawanda, kusanganisira dopamine, norepinephrine, uye histamine, kukurudzira kumuka uye kuziva basa.
Benefits: Inoshandiswa kuvandudza kusvinura, kuisa pfungwa, uye kugona kwekuziva.
Kukanganisa: Modafinil inogona kukonzera migumisiro yakadai sekushaya hope, kuzvidya mwoyo, uye musoro. Mushonga zvakare wakanyorwa nachiremba munyika dzakawanda.
Kuenzanisa: Modafinil neAlpha GPC zvose zvinosimudzira basa rekuziva, asi nenzira dzakasiyana. Modafinil yakawanda pamusoro pekusimudzira kumuka uye kusvinura, nepo Alpha GPC inotarisa pane acetylcholine uye ndangariro. Nekushandisa kwenguva refu, iyo Alpha GPC inogona kunge iri sarudzo yakachengeteka.
Tisati tapinda mune zvekuchengetedza, zvinodikanwa kuti tinzwisise kuti Alpha GPC inoshanda sei. Kana ikadyiwa, Alpha GPC inoshandurwa kuita choline, iyo inobva yakurudzira kuumbwa kweacetylcholine. Iyi neurotransmitter inoita basa rakakosha muakasiyana emabasa ekuziva, anosanganisira kutarisisa, kudzidza, uye ndangariro. Zvidzidzo zvakawanda zvakaratidza kuti Alpha GPC inogona kuvandudza mashandiro enjere, kunyanya muvakuru vakuru uye vanhu vane hurema hwekuziva.
Zvidzidzo zvekiriniki uye kuchengeteka
1. Zvidzidzo zvevanhu
Zvidzidzo zvakawanda zvekiriniki zvakaongorora kuchengetedzwa uye kushanda kweAlpha GPC. Chidzidzo chakabudiswa muInternational Journal of Medical Research chakawana kuti kutora 1,200 mg yeAlpha GPC zuva nezuva kwakatenderwa zvakanaka. Maside effects akataurwa nevatori vechikamu aive mashoma uye kazhinji akapfava, kusanganisira kutemwa nemusoro, dzungu uye matambudziko emudumbu.
Imwe ongororo yakabudiswa muClinical Therapeutics yakaongorora kuchengetedzwa kwenguva refu kweAlpha GPC kune varwere vane chirwere cheAlzheimer. Chidzidzo chacho chakagumisa kuti Alpha GPC yakachengeteka kuti ishandiswe kwenguva refu, isina migumisiro inokosha yakataurwa.
2. Tsvakurudzo yemhuka
Zvidzidzo zvemhuka zvakare zvinotsigira kuchengetedzwa kweAlpha GPC. Tsvagiridzo yakaburitswa muChikafu uye Chemical Toxicology yakawana kuti Alpha GPC haina kukonzera chero chepfu mhedzisiro mumakonzo, kunyangwe pamadosi akanyanya. Izvi zvakawanikwa zvinoratidza kuti Alpha GPC ine yakafara chengetedzo muganho, ichiita kuti ive yakachengeteka yekuwedzera kune vanhu.
Ndiani anofanira kudzivirira Alpha GPC?
Nepo Alpha GPC kazhinji yakachengeteka kune vanhu vazhinji, vamwe vanhu vanofanirwa kungwarira:
1. Vakadzi vane pamuviri uye vanoyamwisa: Pane zvidzidzo zvishoma pamusoro pekuchengetedzwa kweAlpha GPC muvakadzi vane pamuviri uye vanoyamwisa. Zvinokurudzirwa kuonana nemupi wehutano usati washandisa kuwedzera uku.
2. Vanhu vane matambudziko emwoyo: Alpha GPC inogona kukanganisa ropa uye kurova kwemwoyo. Vanhu vane chirwere chemwoyo vanofanira kubvunza mupi wehutano vasati vashandisa.
3. Vanhu vanotora mishonga: Alpha GPC inogona kuwirirana nemimwe mishonga, kusanganisira anticholinergics uye mishonga yeropa. Kana uri kutora mishonga, nguva dzose taura nemutarisiri wako wehutano.
1. Kuchena uye Hunhu
Kuchena uye hunhu hweAlpha GPC hupfu hwakakosha zvakanyanya. Yemhando yepamusoro Alpha GPC inofanirwa kunge isina zvinosvibisa uye mafirita. Tarisa zvigadzirwa izvo zviri wechitatu-bato zvakaedzwa kuchena uye potency. Zvigadzirwa zvinozivikanwa zvinowanzopa Chitupa cheKuongorora (COA) kuratidza kunaka kwechigadzirwa.
2. Dosage uye kuisa pfungwa
Alpha GPC yekuwedzera inowanikwa mune akasiyana madosi uye kutarisisa. Iyo yakanyanya kuwanda ndeye 50% uye 99%. Iyo 99% yekumisikidza inoshanda zvakanyanya uye inoda diki dosi kuti iwane mhedzisiro yaunoda. Zvisinei, inodhurawo. Funga bhajeti yako uye yaunoda potency pakusarudza yekuisa pfungwa.
3. Chigadzirwa fomu
Alpha GPC inowanikwa nenzira dzakasiyana, kusanganisira hupfu, capsules, uye mvura. Imwe neimwe fomu ine zvayakanakira nezvayakaipira. Powdered Alpha GPC inoshanda zvakasiyana-siyana uye inogona kusanganiswa nyore nyore nezvimwe zvinowedzera kana zvinwiwa. Capsules zviri nyore uye pre-kuyerwa, yakanakira kutora pakuenda. Liquid Alpha GPC inotora nekukurumidza asi inogona kuva nehupenyu hupfupi hwesherufu. Sarudza iyo fomati inonyatsoenderana nemararamiro ako uye zvaunofarira.
4. Mukurumbira wechiratidzo
Mukurumbira wechiratidzo chinhu chakakosha kufunga. Mabhureki ane mukurumbira ane ongororo yakanaka yevatengi anowanzo kupa zvigadzirwa zvemhando yepamusoro. Tsvakurudza nhoroondo yemhando, mhinduro yemutengi, uye chero zvitupa zvavangave nazvo. Dzivisa mhando dzine nhoroondo yekurangarira kana ongororo dzisina kunaka.
5. Mutengo uye kukosha
Mutengo unogara uchitariswa kana uchitenga zvekuwedzera. Zvisinei, sarudzo yakachipa haisi nguva dzose yakanakisisa. Enzanisa mitengo pagiramu kana kushanda kuti uone kukosha kwemari. Funga nezvemhando yechigadzirwa, kusungirirwa kwayo, uye chero humwe bhenefiti hwainogona kupa.
6. Zvimwe zvinoshandiswa
Zvimwe zvigadzirwa zveAlpha GPC zvinogona kunge zvine zvimwe zvinongedzo, senge mamwe ma nootropics, mavhitaminzi kana zvicherwa. Izvi zvinowedzera zvinongedzo zvinogona kuwedzera kushanda kwese kwekuwedzera. Zvisinei, ivo vanowedzerawo njodzi yemigumisiro kana kusangana nemimwe mishonga. Verenga chinyorwa chacho zvakanaka uye bvunza nyanzvi yako yehutano kana uine mibvunzo.
7. Ongororo yeVatengi uye Zvipupuriro
Ongororo yemutengi uye zvipupuriro zvinogona kupa ruzivo rwakakosha mukubudirira kwechigadzirwa uye mhando. Tsvaga wongororo kubva kune vakasimbiswa vatengi uye ona chero nyaya dzinodzokororwa kana kurumbidza. Ramba uchifunga kuti zviitiko zvega zvinogona kusiyana, asi maitiro emhinduro dzakanaka kana dzisina kunaka anogona kuratidza hutano hwese hwechigadzirwa.
Suzhou Myland Pharm & Nutrition Inc. ndeye FDA-yakanyoreswa mugadziri inopa yemhando yepamusoro uye yakakwirira-kuchena Alpha GPC hupfu.
PaSuzhou Myland Pharm takazvipira kupa zvigadzirwa zvemhando yepamusoro nemitengo yakanakisa. Yedu Alpha GPC poda yakaedzwa zvakasimba kuchena uye potency, kuve nechokwadi kuti iwe unowana yemhando yepamusoro yekuwedzera yaunogona kuvimba nayo. Kunyangwe iwe uchida kutsigira hutano hweserura, kuwedzera immune system yako kana kuwedzera hutano hwese, yedu Alpha GPC hupfu ndiyo sarudzo yakakwana.
Iine makore makumi matatu echiitiko uye ichisundwa nehunyanzvi hwepamusoro uye akakwenenzverwa zvakanyanya R&D mazano, Suzhou Myland Pharm yakagadzira mhando yezvigadzirwa zvemakwikwi uye ive yekuvandudza hupenyu hwesainzi yekuwedzera, tsika synthesis uye kugadzira masevhisi kambani.
Uye zvakare, Suzhou Myland Pharm zvakare iri FDA-yakanyoreswa mugadziri. Zviwanikwa zvekambani zveR&D, zvivakwa zvekugadzira, uye zviridzwa zvekuongorora ndezvemazuva ano uye zvinoshanda, uye zvinogona kugadzira makemikari kubva kumamirigiramu kusvika kumatani muchiyero, uye zvinoenderana neISO 9001 zviyero uye kugadzirwa kweGMP.
Mubvunzo: Chii chinonzi Alpha-GPC?
A: Alpha-GPC (L-Alpha glycerylphosphorylcholine) inhengo yechisikigo choline inowanikwa muuropi. Inowanikwawo sechikafu chekuwedzera uye inozivikanwa nekugona kwayo kuziva-inosimudzira zvivakwa. Alpha-GPC inowanzoshandiswa kutsigira hutano hwehuropi, kuvandudza ndangariro, uye kuwedzera kujeka kwepfungwa.
Q:Alpha-GPC inoshanda sei?
A: Alpha-GPC inoshanda nekuwedzera mazinga eacetylcholine muuropi. Acetylcholine inonzi neurotransmitter inoita basa rakakosha mukuumbwa kwendangariro, kudzidza, uye kugona kwekuziva. Nekuwedzera acetylcholine mazinga, Alpha-GPC inogona kubatsira kuvandudza kugona kwekuziva uye kutsigira hutano hwehuropi.
Q:3. Ndeapi mabhenefiti ekutora Alpha-GPC?
A: Mabhenefiti ekutanga ekutora Alpha-GPC anosanganisira:
-Yakawedzera ndangariro uye kugona kudzidza
-Kunatsiridza kujeka kwepfungwa uye kutarisa
- Tsigiro yehutano hwehuropi hwese
-Inogoneka neuroprotective mhedzisiro, inogona kubatsira mukudzivirira kuderera kwekuziva
- Kuwedzera kwekuita kwemuviri, kunyanya muvatambi, nekuda kwebasa rayo mukusimudzira kuburitswa kwekukura kwehomoni
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Nguva yekutumira: Sep-23-2024