Mumakore achangopfuura, vanhu vakararama hupenyu hune hanya nehutano hwakanyanya, uye mukutsvaga kwehutano hwakanyanya uye hutano, tinowanzo tsvaga mhinduro dzechisikigo kune dzakasiyana siyana. Imwe inovimbisa yekuwedzera iyo yakawana kutariswa mumakore achangopfuura palmitoylethanolamide (PEA). Inozivikanwa nekugona kwayo kurapa mabhenefiti, PEA yakadzidzwa zvakanyanya nekuda kwekugona kwayo kuderedza marwadzo, kuzvimba, uye kuwedzera hutano hwese.
Palmitoylethanolamide (PEA) inongoitika fatty acid inogadzirwa nemiviri yedu mukupindura kuzvimba nekurwadziwa. Iyo ndeyekirasi yemakomponi inozivikanwa seN-acylethanolamines (NAE), iyo inoshanda senge endogenous fatty acid amides, lipid molecules inobatanidzwa mukugadzirisa kwakasiyana kwemaitiro emuviri. Yakatanga kuwanikwa muma1950, asi kuporesa kwayo hakuna kuwanikwa kusvika pave paya.
PEA iripo mune akasiyana matishu emunhu uye yakawanikwa ichiita basa rakakosha mukugadzirisa uye kugadzirisa maitiro ezvirwere zvemuviri uye kuzvimba.
Iyo inozivikanwa kupindirana nemamwe ma receptors mumuviri, kusanganisira peroxisome proliferator-activated receptor-alpha (PPAR-α), iyo inobatanidzwa mukudzora kuzvimba. Nekuita PPAR-α, PEA inobatsira kurambidza kugadzirwa kwemamorekuru e-pro-inflammatory, ichiwedzera maitiro emuviri ekurwisa-kuzvimba.
PEA inoshanda nekudzivisa kushandiswa kwemasero anokosha anonzi mast cells, anosunungura vapomeri vanopisa uye kukonzera marwadzo uye allergies. Nekudzikisa mast cell activation, PEA inobatsira kuderedza marwadzo nekuvandudza hupenyu hwese.
Zvidzidzo zvakaratidza kuti PEA inogona kuita basa rekudzivirira muzvirwere zvakasiyana-siyana zvetsinga nekudzivirira kukuvadzwa neuronal uye nekusimudzira kukura uye kupona kwemasero etsinga.
PEA inoshanda nekutarisa uye kusunga kune chaiyo receptor inonzi peroxisome proliferator-activated receptor-alpha (PPAR-α). Iyi receptor inoita basa rakakosha mukudzora kuzvimba uye kuona kurwadziwa. Nekuita PPAR-alpha receptors, PEA inobatsira kuderedza kuzvimba uye kubvisa marwadzo.
Palmitoylethanolamide (PEA) Mabhenefiti uye Mashandisiro:
●Pain management: PEA yakaratidza migumisiro inovimbisa mukurapa kwemarudzi akasiyana-siyana emarwadzo, kusanganisira kurwadziwa kusingaperi, kurwadziwa kweuropathic, uye kurwadziwa kunopisa. Inoshanda nekudzikisa kuzvimba uye kugadzirisa masaini ekurwadziwa, kupa zororo kune vanhu vanoramba vachirwadziwa.
●Neuroprotective: PEA yakawanikwa iine neuroprotective properties, zvinoreva kuti inobatsira kuchengetedza nekutsigira hutano hwemasero etsinga. Izvi zvinoita kuti zvive zvinobatsira kuzvirwere zvakaita semultiple sclerosis, chirwere cheAlzheimer uye chirwere cheParkinson, umo kukuvara kwesero retsinga uye kuzvimba kunoita basa rakakosha.
●Anti-inflammatory effect: PEA ine simba rinopesana nekuputika uye inobatsira kune zvakasiyana-siyana zvirwere zvinopisa, zvakadai searthritis, irritable bowel syndrome (IBS) uye asthma. Inobatsira kuderedza kugadzirwa kwepro-inflammatory molecules, nokudaro kuderedza kuzvimba uye zviratidzo zvayo zvinobatanidzwa.
●Rutsigiro rwekudzivirira muviri: PEA yakaratidzwa kuva immunomodulatory, zvinoreva kuti inobatsira kudzora uye kugadzirisa maitiro ekudzivirira. Izvi zvinogona kubatsira muzvirwere zve autoimmune, senge rheumatoid arthritis uye lupus, umo immune system inokanganisa matishu ayo.
●Antidepressant uye anxiolytic mhedzisiro: PEA yakawanikwa iine zvinogona antidepressant uye anxiolytic properties. Inobatsira kudzora manzwiro uye kuderedza zviratidzo zvekuora mwoyo uye kuzvidya mwoyo nekugadzirisa zvakasiyana-siyana neurotransmitters inobatanidzwa mukugadzirisa mafungiro, zvakadai se serotonin uye dopamine.
●Utano hweganda: PEA yakawanikwa iine ganda-inozorodza uye anti-itch properties, zvichiita kuti ive inobatsira mukurapa kwemarudzi akasiyana-siyana eganda, kusanganisira eczema, psoriasis, uye dermatitis. Inobatsira kuderedza kuzvimba uye kuchenesa, kukurudzira hutano, ganda rakasununguka.
CBD, yakabviswa mumuti wehemp, inozivikanwa nekugona kwayo kupa mabhenefiti akadai sekuzorodza marwadzo, kuderedza kusagadzikana uye kurara kwakaringana. Ukuwo, PEA, inowanzoitika fatty acid amide, yakadzidzwa zvakanyanya nekuda kweiyo anti-inflammatory uye analgesic properties. Ose ari maviri emakemikari aya anogadzirwa ega mumiviri yedu uye anogona kuwanikwa mune zvimwe zvekudya.
Imwe yemisiyano mikuru pakati pePEA neCBD mashandiro anoita imwe neimwe mumuviri wedu. CBD inonyanya kudyidzana neyedu endocannabinoid system (ECS), network yezvinogamuchirika inodzora maitiro akasiyana-siyana emuviri, kusanganisira marwadzo ekuona, manzwiro, uye kuzvimba. CBD inokanganisa zvisina kunanga iyo ECS nekusimudzira endocannabinoid kugadzirwa kana kuvharidzira kuderedzwa kwavo.
Nekudaro, PEA inoshanda nenzira dzakasiyana. Inotarisa uye inogadzirisa basa remamwe akawanda masisitimu mumuviri wedu, kunyanya iwo anobatanidzwa mukugadzirisa marwadzo uye kuzvimba. PEA inopindirana nevakawanda vanogamuchira, zvakadai se peroxisome proliferator-activated receptor-α (PPAR-α), iyo inoita basa rinokosha mukugadzirisa marwadzo.
Nepo zvese PEA neCBD zvine anti-kuzvimba mhedzisiro, kuita kwePEA kunoratidzika kunge kuri munharaunda, kunanga chaiwo mamorekuru anokonzera kurwadziwa, nepo CBD ine mhedzisiro yakakura pakupindura kwese kwekuzvimba. Musiyano uyu wemashini unogona kutsanangura kuti sei PEA ichiwanzo shandiswa kugadzirisa marwadzo emunharaunda, nepo CBD ichiwanzo shandiswa zvakanyanya kurapa systemic kuzvimba.
Imwe pfungwa yemusiyano inzvimbo yepamutemo yemakomponi maviri mune dzimwe nyika. CBD, inotorwa kubva kuhemp, iri pasi pezvirambidzo zvakasiyana siyana zvemutemo uye mirau, kunyanya nekuda kwekubatana kwayo nehemp. Mukupesana, PEA inorongedzerwa sechikafu chekuwedzera uye inowanzoonekwa yakachengeteka uye zviri pamutemo kushandisa.
Kunyangwe ese ari maviri makomisheni ane anogona kurapa zvivakwa, iwo ekuchengetedza profiles anosiyana. CBD yakadzidzwa zvakanyanya uye inowanzoonekwa yakachengeteka, ine mashoma akataurwa mhedzisiro. Zvisinei, inogona kuwirirana nemimwe mishonga uye inogona kunge isina kukodzera kumunhu wose, kunyanya avo vane chirwere chechiropa. PEA, kune rumwe rutivi, chinhu chinongoitika mumiviri yedu uye yakashandiswa zvakachengeteka sechikafu chekuwedzera kwemakumi emakore.
Zvakakodzera kutaura kuti PEA neCBD hadzisi nzira dzakasarudzika. Muchokwadi, vamwe vanhu vanosarudza kushandisa ese ari maviri makomisheni pamwe chete nekuti anogona kunge aine mhedzisiro. Semuyenzaniso, iyo yakakura anti-kuzvimba mhedzisiro yeCBD inogona kusanganiswa neakanyanya topical analgesic zvimiro zvePEA yeimwe nzira yakazara yekudzora marwadzo.
Dosage Guidelines:
Kana uchifunga nezve yakakwana dosage yepalmitoylethanolamide, zvakakosha kuyeuka kuti zvido zvemunhu zvinogona kusiyana. Zvinogara zvichikurudzirwa kubvunza nyanzvi yezvehutano inokwanisa usati watanga chero chirongwa chitsva chekuwedzera. Nekudaro, heano mamwe akajairwa dosage nhungamiro kuti iwe utange:
1.Tanga nedosi yakaderera: Kutanga nedosi yakaderera inodzivirira muviri kubva pakuremerwa uye inobvumira kugadzirisa.
2.Zvishoma nezvishoma kuwedzera: mushure memazuva mashoma, kana pasina kukanganisa kunoitika, zvakakosha kuziva kuti kushivirira uye kusachinja-chinja kwakakosha kana uchibatanidza PEA mumaitiro ako ezuva nezuva.
3.Tarisa mhinduro yemunhu mumwe nemumwe: Muviri wemunhu wese wakasiyana, saka zvinogona kutora nguva kuti utarise mwero wakanakisa wezvido zvako. Nyatsocherechedza kuti muviri wako unopindura sei, uye bvunza nyanzvi yehutano kuti uwane mazano munzira.
nhungamiro yemushandisi:
Pamusoro pedosi, zvakakosha zvakaenzana kuziva maitiro akanakisa ekushandisa palmitoylethanolamide. Funga nezvemashandisirwo anotevera nhungamiro kuti uwedzere mabhenefiti angangoita ePEA:
1.Kuenderana kwakakosha: Kuti uwane huwandu hwakazara hwekurapa kwePEA, kushandiswa kwakafanana kwakakosha. Kutora dosi yakakurudzirwa nguva nenguva kwenguva yakareba kunobatsira muviri kugadzirisa uye kukwidziridza mabhenefiti ePEA.
2.Vaviri vane kudya kwakaringana: PEA inoshanda zvakabatana nekudya kune hutano. Kuwedzera nekudya kwakadzikama kwakapfuma mune zvakakosha zvinovaka muviri kunogona kuwedzera mabhenefiti ayo uye kukurudzira hutano hwese.
3.Batanidza shanduko yemararamiro: Kutora mararamiro ane hutano, kusanganisira maekisesaizi, kudzora kushushikana, uye kurara kwemhando, zvinogona kuwedzera mhedzisiro yePEA. Kuchinja kwemararamiro kunofambidzana nePEA yekuwedzera kune hutano hwakakwana.
Mubvunzo: Palmitoylethanolamide ingawanikwa sei?
A: Palmitoylethanolamide inowanikwa sechikafu chekuwedzera muchimiro che capsules kana hupfu. Inogona kutengwa pane-the-counter kubva kune hutano chikafu zvitoro, ma pharmacy, kana online vatengesi. Nekudaro, zvinokurudzirwa kubvunza nyanzvi yezvehutano usati watanga kushandisa, kunyanya kana uine chero mamiriro ehutano ari pasi pasi kana uri kutora mushonga.
Mubvunzo: Palmitoylethanolamide inogona kushandiswa seyakamira yega kana musanganiswa nemamwe marapirwo?
A: Palmitoylethanolamide inogona kushandiswa seyakamira yega kune mamwe mamiriro, kunyanya kusingaperi marwadzo ekugadzirisa. Nekudaro, mune zvimwe zviitiko, inogona kunyanya kushanda kana ichishandiswa seye adjunct therapy pamwe neakajairika marapirwo. Kushandiswa kwepalmitoylethanolamide kunofanira kukurukurwa nenyanzvi yezvehutano kuti ione nzira yakakodzera yekurapa kune zvinodiwa nemunhu.
Disclaimer: Ichi chinyorwa ndechezvinangwa zveruzivo chete uye hachifanirwe kutorwa sezano rekurapa. Nguva dzose bvunza nyanzvi yezvehutano usati washandisa chero chekuwedzera kana kushandura hutano hwehutano hwako.
Nguva yekutumira: Aug-21-2023
