Kuongorora Urolithin A uye B: Ramangwana Rokurasikirwa Kwehuremu uye Hutano Hwekuwedzera

Mumakore achangopfuura, chitarisiko chave urolithins, kunyanya urolithin A uye B, seanovimbisa makomisheni anobva kumetabolism yepolyphenols inowanikwa mumapomegranati nemimwe michero. Aya metabolites akawana kutariswa kweanogona kubatsira hutano, kusanganisira kuonda, anti-kuchembera zvivakwa, uye hutano hwese.

Kunzwisisa Urolithins: A uye B

Urolithins mametabolites anogadzirwa nemudumbu mabhakitiriya paanoputsa ellagitannins, rudzi rwepolyphenol inowanikwa mumichero yakasiyana-siyana, kunyanya matamba. Pakati pemhando dzakasiyana dzeurolithin, urolithin A (UA) uyeurolithin B (UB) ndivo vakanyanya kudzidzwa.

Urolithin A yakabatanidzwa kune akati wandei mabhenefiti ehutano, kusanganisira yakagadziridzwa mitochondrial basa, yakasimbiswa tsandanyama hutano, uye inogona anti-kuzvimba mhedzisiro. Tsvagiridzo inoratidza kuti UA inogona kuita basa mukusimudzira autophagy, maitiro anobatsira muviri kuburitsa maseru akakuvadzwa uye kugadzira patsva. Uku kukwanisa kuvandudza kunonyanya kufadza kune avo vanotarisa kuchengetedza mhasuru uye simba rose sezvavanokura.

Urolithin B kune rumwe rutivi, yakadzidzwa zvishoma asi inofungidzirwa kuti ine seti yayo yehutano. Zvimwe zvidzidzo zvinoratidza kuti UB inogonawo kutsigira mitochondrial basa uye kuratidza antioxidant properties, kunyange zvazvo migumisiro yayo isina kunyatsonyorwa seAU.

Urolithin A uye Kurasikirwa Kwehuremu

Imwe yenzvimbo dzinonakidza dzekutsvaga dzakatenderedza urolithin A ibasa rayo rinogona kuita mukurasikirwa nehuremu. Ongororo dzinoverengeka dzakaratidza kuti UA inogona kubatsira kudzora metabolism uye kukurudzira kurasikirwa kwemafuta. Semuenzaniso, ongororo yakabudiswa mujenari *Nature* yakawana izvozvourolithin Ainogona kuwedzera kugona kwemuviri kupisa mafuta nekuvandudza mitochondrial basa. Izvi zvinonyanya kukosha sezvo hutano hwemitochondrial hwakakosha pakugadzira simba uye metabolism.

Uyezve, urolithin A yakaratidzwa inokanganisa gut microbiome zvakanaka. Iyo ine hutano gut microbiome yakakosha kune inoshanda kugaya uye metabolism, uye inogona kuita basa rakakosha mukutonga uremu. Nekusimudzira yakaringana gut nharaunda, UA inogona kubatsira vanhu kuti vazadzise zvinangwa zvavo zvekurasikirwa nehuremu zvakanyanya.

Yakachena Urolithin A Supplements

Nekufarira kuri kukura kweurolithin A, makambani mazhinji atanga kupa yakachena urolithin A yekuwedzera. Izvi zvinowedzera zvinotengeswa senzira yekubatanidza mabhenefiti ekomboni iyi pasina kuda kudya yakawanda yemapomegranate kana zvimwe zvekudya zvine ellagitannin.

Kana uchifunga nezve yakachena urolithin A yekuwedzera, zvakakosha kuti utsvage zvigadzirwa zvinotsigirwa netsvakiridzo yesainzi uye zvakaedzwa zvakaomarara kuchena uye kushanda. Yepamusoro-mhando yekuwedzera inofanirwa kunge iine yakajairwa dosi yeurolithin A kuve nechokwadi chekuti vashandisi vanowana mabhenefiti anotarisirwa.

Iyo Yakanakisa Urolithin A Yekuwedzera paMusika

Sezvo kudiwa kweurolithin A yekuwedzera kuri kukura, mhando dzakati wandei dzakabuda sevatungamiriri mumusika. Heano mamwe eakanakisa urolithin A anowedzera aripo parizvino:

. Izvi zvigadzirwa zvinopa zvikomborero zvezvose muchero uye metabolites yayo.

2. Myland Nutraceuticals Urolithin A: Chiratidzo ichi chinopa urolithin A yekuwedzera iyo isina madhipatimendi uye mafirita, zvichiita kuti ive sarudzo yakanaka kune avo vari kutsvaga nzira yakatwasuka yekuwedzera.

Mhedziso

Urolithin A uye B inomiririra inonakidza nzvimbo yekutsvagisa ine zvakakosha kune hutano uye hutano. Nepo urolithin A inoratidza chivimbiso mukutsigira uremu uye hutano hwese, urolithin B inogona kubatsira kune izvi zvakanaka, kunyangwe zvishoma. Sezvo sainzi yakatenderedza makomponi aya ichiramba ichishanduka, saizvozvowo sarudzo dziripo kune vatengi vari kutsvaga kusimudzira hutano hwavo kuburikidza nekuwedzera.

Kune avo vanofarira kuongorora zvingango batsira zveurolithin A, zvakakosha kuti vasarudze zvemhando yepamusoro zvekuwedzera izvo zvinotsigirwa netsvagiridzo. Senguva dzose, vanhu vanofanirwa kubvunzana nevarapi vehutano vasati vatanga chero chirongwa chitsva chekuwedzera, kunyanya kana vaine hutano huri pasi pemamiriro ezvinhu kana kuti vari kutora mimwe mishonga.

Muchidimbu, urolithin A uye B inopfuura kungoita buzzwords muindasitiri yekuwedzera yehutano; ivo vanomiririra muganhu mutsva mukunzwisisa kwedu kuti maumbirwo echisikigo anogona sei kutsigira uremu, hutano hwemaserura, uye kugara zvakanaka. Sezvo tsvagiridzo irikuenderera mberi, tinogona kuwana zvinotonakidza zvikumbiro zveaya ane simba metabolites mumakore anotevera.