Lithium orotatema supplements awana mukurumbira mumakore achangopfuura nekuda kwehutano hwavo hunobatsira. Nekudaro, kuchine kuvhiringika kwakawanda uye kusaziva kwakatenderedza iyi mineral uye kushandiswa kwayo mukuwedzera fomu. Muchirongwa ichi chakazara, tichavhara zvinhu zvose zvaunoda kuziva pamusoro pe lithium orotate supplements.Kutanga uye kunyanya, zvakakosha kunzwisisa kuti lithium orotate isimbi yakasikwa inoshandiswa kutsigira hutano hwepfungwa uye hutano hwakakwana. Iyo imhando ye lithium inosanganiswa neorotic acid, iyo inobatsira iyo mineral kupinda mukati mesero membranes zvinobudirira. Izvi zvinoreva kuti yakaderera doses ye lithium orotate inogona kushandiswa ichienzaniswa nemamwe marudzi e lithium, kuderedza njodzi yemhedzisiro.
Ndezvipi zvinobatsira zve lithium kune uropi?
Lithium orotate munyu wakaumbwa neorotic acid uye lithium. Zita rayo rakazara rinonzi lithium orotate monohydrate (Orotic acid lithium salt monohydrate), uye chimiro chayo che molecular ndeye C5H3LIN2O4H2O. Lithium uye orotic acid ion haina kusungwa zvine hushamwari asi inogona kupatsanura mukugadzirisa kugadzira yemahara lithium ions. Tsvagiridzo inoratidza kuti lithium orotate yakawanda bioavailable kupfuura zvinodhaka zvinodhaka lithium carbonate kana lithium citrate (US FDA-inobvumidzwa mishonga).
Lithium mushonga unowanzoshandiswa mukurapa kurapa kuora mwoyo, bipolar disorder, uye zvimwe zvirwere zvepfungwa. Zvisinei, chiyero chekunwa kwe lithium carbonate kana lithium citrate yakaderera, uye mazinga akakwirira anodiwa kuti abudise maitiro ekurapa. Nokudaro, vane migumisiro yakakura uye ine chepfu. Nekudaro, yakaderera-dose lithium orotate ine inoenderana kurapa mhedzisiro uye ine mishoma mhedzisiro.
Kare kuma1970s, lithium orotate yakatengeswa sechikafu chekuwedzera kune zvimwe zvirwere zvepfungwa, zvakadai sedoro uye chirwere cheAlzheimer.
Chikamu cheuchapupu ndeichi:
Chirwere cheAlzheimer: Tsvagiridzo inoratidza kuti lithium orotate ine yakakwira bioavailability uye inogona kuita zvakananga pamitochondria uye glial cell membranes kupa rutsigiro nekudzivirira kune neuroni uye kunonoka kana kuvandudza neurodegenerative zvirwere senge chirwere cheAlzheimer.
Neuroprotection uye kuvandudza ndangariro: Tsvagiridzo yazvino mumushonga weAmerica yakawana kuti lithium haingobatsiri kuchengetedza masero ehuropi kubva pakufa nguva isati yakwana, inogona kutokurudzira kuvandudzwa kwesero rehuropi. Naizvozvo, lithium inogona kuchengetedza iyo hippocampus kubva mukukuvadzwa uye kuchengetedza kana kuwedzera ndangariro basa.
Mood stabilizers: Lithium (lithium carbonate kana lithium citrate) inoshandiswa mukurapa kurapa kuora mwoyo uye bipolar disorder. Saizvozvo, lithium orotate ine mhedzisiro iyi. Nekuti dosage yakashandiswa idiki zvakanyanya kana ichienzaniswa nenguva yakafanana gore rapfuura, inotenderwa zvakanaka uye ine mishoma mhedzisiro.
Chii chinonzi lithium orotate chakanakira?
Chirwere cheAlzheimer chirwere chinodzikira chetsinga. Mukiriniki, varwere vanozosangana nezviratidzo zvakadai sekukanganisa ndangariro, amnesia, uye kusashanda zvakanaka. Chikonzero chikuru chechirwere ichi hachisati chaonekwa. Pakati pavo, chirwere cheAlzheimer chinonziwo chirwere cheAlzheimer. Vazhinji varwere vanokura chirwere ichi vasati vava nemakore 65. Iri iboka rezvirwere zvakasiyana-siyana zvinokonzerwa nemhando dzakasiyana-siyana. Uyezve, varwere vakawanda vanotanga chirwere ichi mushure memakore makumi mashanu. Mune zviratidzo zvekutanga, pachava nekukanganwa kunowedzera.
Muchikamu chekutanga, kukwanisa kuyeuka kwemurwere kunoderera zvishoma nezvishoma, somuenzaniso, achakurumidza kukanganwa zvaanenge achangobva kutaura kana zvaakaita, uye kukwanisa kuongorora kufunga kwemurwere uye kukwanisa kutonga zvichadererawo, asi panguva imwe chete, zvimwe zvinhu. akadzidza kare achadererawo. Murwere achange achine ndangariro dzebasa racho kana unyanzvi. Mushure mokunge chirwere chacho chawedzera, zviratidzo zvekutanga zvemurwere zvichava pachena kuona-spatial cognitive kukanganisa, uye zvichange zvakaoma kupfeka.
Kunyanya, kushandiswa kwe lithium kwakabatanidzwa ne 44% yakaderera yengozi ye dementia, 45% yakaderera mungozi yeAlzheimer's disease (AD), uye 64% yakaderera ngozi yevascular dementia (VD).
Izvi zvinoreva kuti lithium salt inogona kuve nzira yekudzivirira yedementia yakadai seAD.
Dementia inoreva kukanganiswa kwekuziva kwakanyanya uye kunoramba kuripo. Kliniki, inoratidzirwa nekunonoka-kutanga kuderera kwepfungwa, kunoperekedzwa neakasiyana madhigirii ekuchinja kwehunhu, asi pasina kukanganisa kwekuziva. Iboka remakiriniki syndromes pane chirwere chakazvimirira. Pane zvakawanda zvinokonzeresa dementia, asi dementia yakawanda inowanzokonzerwa nekukuvadzwa kwehuropi kana kukuvara kwehuropi, senge hosha yeAlzheimer, chirwere cheParkinson, kukuvara kwehuropi, nezvimwe.
Iyo neuroprotective mhedzisiro yelithium munyu
Ongororo ye lithium mhedzisiro pahuropi neropa (Ongororo yelithium mhedzisiro pauropi neropa) Ongororo iyi inoti: "Mumhuka, lithium inogadzirisa neurotrophins, kusanganisira brain-derived neurotrophic factor (BDNF), nerve growth factor, nerve Trophin 3 (NT3) , uye zvinogamuchirika zveizvi kukura zvinhu muuropi.
Lithium inokurudzirawo kuwanda kwemasero emasero, anosanganisira mapfupa emapfupa uye neural stem masero munzvimbo ye subventricular, striatum, uye forebrain. Kukurudzira endogenous neural stem masero kunogona kutsanangura kuti sei lithium inowedzera huropi masero uye huwandu muvarwere vane bipolar disorder. “
Pamusoro pemhedzisiro iri pamusoro, lithium inogonawo kuvandudza immune system yemuviri, kutonga central nervous system chiitiko, kuita sedation, runyararo, neuroprotection, uye kudzora tsinga kusagadzikana. Maviri meta-analyse uye a randomized controlled trial akavhura mikova mitsva mu-anti-dementia treatments, zvichiratidza kuti lithium ine simba rakanaka pakuita kwekuziva muvarwere vane mild cognitive impairment (MCI) uye AD.
Ndiani asingafaniri kutora lithium orotate?
Vakadzi Nemimba Nevanoyamwisa
Vakadzi vane pamuviri uye vanoyamwisa vanofanira kudzivisa kutora lithium orotate. Kushandiswa kwe lithium orotate panguva yekuzvitakura uye lactation hakuna kuongororwa zvakanyanya, uye kune ruzivo rushoma runowanikwa pamusoro pekuchengetedza kwayo kune vanhu ava. Zvakakosha kuti vakadzi vane pamuviri kana vanoyamwisa vataurirane nemutarisiri wavo wehutano vasati vashandisa chero chekuwedzera, kusanganisira lithium orotate, kuve nechokwadi chekuchengetedzwa kwevose amai nemwana.
Vanhu vane Kidney Disease
Lithium inonyanya kubudiswa kuburikidza neitsvo, uye vanhu vane chirwere chetsvo vanogona kunge vari pangozi yekuwedzera kwe lithium mumuviri. Izvi zvinogona kutungamirira kune lithium toxicity, iyo inogona kutyisa hupenyu. Naizvozvo, vanhu vane chirwere cheitsvo havafanirwe kutora lithium orotate kunze kwekunge vari pasi pekutariswa kwepedyo kwemupi wehutano anogona kutarisa kushanda kweitsvo dzavo uye kugadzirisa dosi zvinoenderana.
Vanhu vane Mwoyo Zvimiro
Lithium orotate inonzi ine zvinogona kuitika pamwoyo, kusanganisira kuchinja kwemoyo uye rhythm. Vanhu vane mwoyo yakagara iripo, yakadai se arrhythmias kana chirwere chemwoyo, vanofanira kungwarira pavanenge vachifunga nezvekushandiswa kwe lithium orotate. Vanhu vane chirwere chemoyo vanofanirwa kutaurirana nemupi wehutano vasati vashandisa lithium orotate kuongorora njodzi dzinogona kuitika uye mabhenefiti zvichienderana nenhoroondo yavo yekurapa.
Vana Nevachiri Kuyaruka
Iko kuchengetedzwa uye kushanda kwe lithium orotate muvana nevechiri kuyaruka haina kunyatsogadziriswa. Nekuda kweizvozvo, zvinowanzokurudzirwa kuti vanhu vari pasi pemakore gumi nemasere vadzivise kushandisa lithium orotate kunze kwekunge vachitungamirwa nemupi wehutano anogona kuongorora kukodzera kwekushandiswa kwayo mune zvimwe zviitiko. Vana nevechiri kuyaruka vane yakasarudzika physiological uye kukura kufunga kunoda kutariswa kana uchifunga nezve kushandiswa kwechero chekuwedzera, kusanganisira lithium orotate.
Vanhu vane Thyroid Disorders
Lithium yave ichizivikanwa kuti inovhiringa thyroid basa, uye vanhu vane utachiona hwehutachiona, hwakadai se hypothyroidism kana hyperthyroidism, vanofanirwa kungwarira kana vachifunga nezve kushandiswa kwe lithium orotate. Migumisiro yelithium pahutano hwethyroid inogona kusiyana kubva kumunhu nemunhu, uye vanhu vane chirwere chetachiona vanofanira kushanda pamwe chete nevanopa hutano hwavo kuti vatarise basa ravo rethyroid kana vachifunga nezvekushandisa lithium orotate.
Maitiro ekuwedzera Lithium
Naizvozvo, zvinogona kuoneka kubva munhaurirano iri pamusoro kuti lithium munyu ine inodzivirira pamasero etsinga zvese mu vivo uye in vitro. Inogona kudzikamisa uye kudzikamisa manzwiro, kudzora kusagadzikana kwetsinga, uye inogona kushandiswa kudzivirira chirwere cheAlzheimer, Huntington's disease, cerebral ischemia, etc. Cerebrovascular disease. Panguva imwecheteyo, inogona zvakare kuvandudza hematopoietic basa uye kuwedzera basa rekudzivirira remunhu.
Lithium chinhu chechisikigo chinowanikwa mumasikirwo, kunyanya chinobva muzviyo nemiriwo. Uye zvakare, mvura yekunwa mune dzimwe nzvimbo ine yakakwirira lithium yemukati, iyo inogona zvakare kupa yakawedzera lithium kudya.
Pamusoro pekuwana diki reti lithium mukudya kwako kwemazuva ese, iwe unogona zvakare kuiwana mune zvekuwedzera.
Suzhou Myland Pharm & Nutrition Inc. yave ichiita bhizinesi rekuwedzera chikafu kubva muna 1992. Ndiyo kambani yekutanga muChina kugadzira nekutengesa mhodzi dzemazambiringa.
Iine makore makumi matatu echiitiko uye ichitungamirwa nehunyanzvi hwepamusoro uye yakagadziridzwa zvakanyanya R&D zano, kambani yakagadzira mhando yezvigadzirwa zvemakwikwi uye ikava yekuvandudza hupenyu hwesainzi yekuwedzera, yetsika synthesis uye kambani yekugadzira masevhisi.
Pamusoro pezvo, Suzhou Myland Pharm & Nutrition Inc. zvakare iri FDA-yakanyoreswa mugadziri. Zviwanikwa zvekambani zveR&D, zvivakwa zvekugadzira, uye zviridzwa zvekuongorora ndezvazvino uye zvinoshanda uye zvinogona kugadzira makemikari kubva kumamirigiramu kusvika kumatani muchiyero, uye zvinoenderana neISO 9001 zviyero uye magadzirirwo ekugadzira GMP.
Nguva yekutumira: Aug-01-2024
