Wanga uchitsvaga nzira yekusimudzira hutano hwako hwese uye kugara zvakanaka? Calcium alpha-ketoglutarate yekuwedzera ndiyo sarudzo yako yakanaka.Calcium alpha-ketoglutarate ikomboni inoita basa rakakosha mukugadzirwa kwesimba remuviri uye metabolism. Ichowo chinhu chakakosha mukuchengetedza mapfupa akasimba uye ane hutano, zvichiita kuti ive chikafu chakakosha chehutano hwese. Nekubatanidza calcium alpha ketoglutarate supplements mumaitiro ako ezuva nezuva, unogona kuwana hutano hwakasiyana-siyana hunosimudzira pfungwa yako yekugara zvakanaka.
Ca-AKGisanganiswa yemamineral calcium uye alpha-ketoglutarate molecule. Alpha-ketoglutarate chinhu chakakosha mukugadzirwa kwesimba remuviri, kunyanya mukutenderera kwe tricarboxylic acid, uko kwakakosha pakugadzirwa kweadenosine triphosphate (ATP), simba guru remuviri.
Mukuwedzera, Ca-AKG inoshanda seKreb cycle metabolite uye α-ketoglutarate inogadzirwa apo masero anoputsa mamorekuru echikafu kune simba. Inobva yayerera mukati nepakati pemaseru, ichigonesa nzira dzakawanda dzekuchengetedza hupenyu uye masisitimu ezviratidzo. Inotoita basa mukutaura kwemajini, ichiita senge nzira yekudzora inoita seinodzivirira zvikanganiso zveDNA zvinyorwa zvinowanzo tungamira kuzvirwere zvakaita segomarara.
Kana munhu asvika kune rimwe zera, chiyero chechisikigo che α-ketoglutarate mumuviri chinoderera, uye kuderera uku kunoenderana nekukwegura.
Pakati pavo, α-ketoglutarate is α-keto acid inoita basa rakakosha mumhando dzakasiyana siyana dzezvipenyu. Pamusoro pezvo, alpha-ketoglutarate zvakare ikemikari inogadzika, zvichireva kuti inogadzirwa nemuviri. Haikwanisi kuwanikwa kuburikidza nekudya, asi zvimwe zvidzidzo zvinoratidza kuti inogona kuchengetedzwa kuburikidza nekutsanya uye kudya kwe ketogenic. Inoratidzika kunge iine nzira ina dzinokosha dzekuita. Izvi zvinosanganisira kuchengetedza metabolism ine hutano, kukurudzira transamination yeakakosha amino acids, kuchengetedza DNA uye kudzvanya kusingaperi kuzvimba. Zvichakadaro, calcium iminerari yakakosha inoita basa rakakosha mumabasa mazhinji emuviri, kusanganisira kumisikidza tsandanyama, neurotransmission, uye hutano hwemapfupa.
Ca-AKG yekuwedzera musanganiswa wecalcium uye alpha-ketoglutarate inopa zvakasiyana siyana zvingangobatsira, zvinosanganisira kuvandudzwa kwemitambo, kukura kwemhasuru, uye rutsigiro rwehutano hwese.
Alpha-ketoglutarateimorekuru inoita basa rakakosha muserura metabolism. Icho chimiro chechisikigo chinowanikwa mumuviri uye chinowanikwawo sechikafu chekuwedzera.
Kuti tipindure mubvunzo uyu, zvakakosha kuti tinzwisise zvikonzero zvekukwegura. Kuchembera idanho rakaomarara rinosanganisira huwandu hwezvinhu zvipenyu uye zvakatipoteredza. Imwe yeakakosha madhiraivha ekuchembera ndiko kuunganidzwa kwekukuvara kweserura uye kusashanda nekufamba kwenguva. Izvi zvinogona kukonzera kuderera kwekushanda kweakasiyana matishu uye nhengo, zvichizotungamira kune hunhu zviratidzo zvekuchembera senge wrinkles, kuderedzwa kwesimba uye kuwedzera kubatwa nechirwere.
Tsvagiridzo inoratidza kuti alpha-ketoglutarate inogona kuve nemukana wekudzoreredza dzimwe shanduko dzine chekuita nezera. Chidzidzo chakaburitswa mujenari Cell Metabolism chakawana kuti kuwedzera kudya kwemakonzo akura nealpha-ketoglutarate kwakagadzira huwandu hwezvakanakira. Izvi zvinosanganisira kuvandudzwa kwebasa remuviri, kuwedzera hupenyu hurefu, uye kuderedzwa kwezviratidzo zvekukwegura muchiropa uye skeletal muscle.
Vatsvakurudzi vakawanawo kuti alpha-ketoglutarate supplementation yakakonzera shanduko mubasa remajini anobatanidzwa mukugadzira simba uye metabolism. Izvi zvinoratidza kuti alpha-ketoglutarate inogona kukwanisa kudzoreredza matishu achembera nekusimudzira kugona kwayo kugadzira simba nekugadzirisa kukuvara.
Pamusoro pemigumisiro yayo pametabolism, alpha-ketoglutarate yakaratidzwa kuva nehuwandu hwezvimwe zvikomborero. Semuenzaniso, inotangira kugadzirwa kwe collagen, chikamu chakakosha cheganda uye mamwe matukisi anobatanidza. Izvi zvinoreva kuti alpha-ketoglutarate inogona kubatsira kuchengetedza chimiro uye basa reganda, zvichibatsira kukurudzira kutaridzika kwepwere.
Calcium iminerari yakakosha inoita basa rakakosha mune zvakawanda zvipenyu maitiro mumuviri. Imwe yeayo mashoma-anozivikanwa mabasa ndeyekuita kwayo pane alpha-ketoglutarate, chikamu chakakosha che citric acid kutenderera.
Chekutanga, zvakakosha kuti unzwisise zvinoitwa nealpha-ketoglutarate mumuviri. Alpha-ketoglutarate inhengo yepakati mu citric acid cycle (inozivikanwawo seKrebs cycle) uye ine basa rekugadzira simba nenzira yeadenosine triphosphate (ATP). Kutenderera uku kunoitika musero mitochondria uye yakakosha kumetabolism yemacarbohydrates, mafuta, uye mapuroteni. Alpha-ketoglutarate inotora chikamu mune akati wandei akakosha biochemical reactions mu citric acid cycle, kusanganisira kushandurwa kwe isocitrate kuita succinyl-CoA.
Tsvagiridzo inoratidza kuti calcium ions inoita basa rakakosha mukugadzirisa basa rema enzymes anosanganisirwa muiyo citric acid kutenderera, kusanganisira ayo anodyidzana nealpha-ketoglutarate. Kunyanya, calcium ions inodzora basa re alpha-ketoglutarate dehydrogenase, iyo inokonzeresa kushandurwa kwe alpha-ketoglutarate kuita succinyl-CoA. Izvi zvinoreva kuti kuvapo kwe calcium kunokanganisa chiyero che α-ketoglutarate metabolism mu citric acid cycle.
Pamusoro pezvo, calcium yakawanikwa inokanganisa alpha-ketoglutarate mazinga mumuviri. Zvidzidzo zvakaratidza kuti kuwedzera kweiyo intracellular calcium mazinga anotungamira mukudzikira kwealpha-ketoglutarate, nepo kuderera kwemazinga ecalcium kune zvinopesana. Izvi zvinosimbisa hukama hwakaoma pakati pecalcium nealpha-ketoglutarate, uye kuti kushanduka kwemazinga ecalcium kunokanganisa sei metabolism yekomboni iyi yakakosha.
Mhedzisiro yecalcium pane alpha-ketoglutarate inowedzera kupfuura iyo citric acid kutenderera. Alpha-ketoglutarate zvakare inotungamira kune synthesis ye glutamate, yakakosha neurotransmitter mukati mepakati tsinga system. Calcium chiratidzo chakawanikwa kuti chigadzirise basa rema enzymes anobatanidzwa mukugadzirwa kwe glutamate kubva ku alpha-ketoglutarate. Izvi zvinoratidza kushanda kwakanyanya kwecalcium paα-ketoglutarate metabolism, kusanganisira basa rayo mune neurotransmission.
1.Anti-kuchembera
Ca-AKG yakaratidzwa kuva inogona kurwisa-kuchembera mhedzisiro padanho remasero. Imwe ongororo yakawana kuti kuwedzera neCa-AKG kwakakonzera kuwedzera kwekuita kwe mitochondria, masimba emasero, ayo anoderera nezera. Nekutsigira mitochondrial basa, Ca-AKG inogona kubatsira kuvandudza hutano hweserura uye kupora, izvo zvingave nemhedzisiro yakakura pahupenyu hwese uye zvirwere zvine chekuita nekuchembera.
Pamusoro pezvo, bepa ra2019 rakaburitswa mupepanhau rakatariswa nevezera Kuchembera rakaratidza kuti alpha-ketoglutarate inogona kuwedzera hupenyu hwema nematodes (inozivikanwawo semaroundworms) uye kuti iyo komputa inogona kuderedza chiitiko cheiyo mTOR nzira. mTOR inhibition inobatanidza nehuwandu hwehutano hunobatsira.Kunyanya, mTOR inhibition inoratidzika kukurudzira sero hupenyu hurefu uye kuderedza dambudziko rezvirwere zvine chokuita nezera nekuwedzera autophagy.
2.Regulates Energy uye Metabolism
Imwe yedzakakosha nzira idzo Ca-AKG inokanganisa simba uye metabolism kuburikidza nebasa rayo mu citric acid kutenderera. Kutenderera uku kune basa rekushandura chikafu chiri muchikafu, senge makabhohaidhiretsi, mafuta, uye mapuroteni, kuita adenosine triphosphate (ATP), iyo inosimbisa simba remuviri. Alpha-ketoglutarate chinhu chakakosha cheiyi kutenderera sezvo ichitora chikamu mune akati wandei akakosha metabolic maitiro. Nekupa muviri sosi yealpha-ketoglutarate muchimiro cheCa-AKG, zvinofungidzirwa kuti vanhu vanogona kutsigira maitiro avo ekugadzira simba, zvichigona kuvandudza huwandu hwesimba uye metabolism.
Pamusoro pezvo, tsvagiridzo inoratidza kuti Ca-AKG inogona zvakare kuve ne antioxidant zvivakwa, izvo zvinogona kuwedzera kutsigira basa rayo mukudzora simba uye metabolism. Oxidative stress inoitika kana paine kusaenzana pakati pekugadzirwa kwemahara radicals uye kugona kwemuviri kurwisa mhedzisiro yavo inokuvadza, uye inobatanidzwa kune huwandu hwezvinetso zvehutano, kusanganisira metabolic kusagadzikana. Nekuita seantioxidant, Ca-AKG inogona kubatsira kuderedza oxidative kusagadzikana, nekudaro ichikurudzira kugadzirwa kwesimba kwakasimba uye metabolism.
3.Healthy Weight Loss and Management
Ca-AKG ndiyo munyu fomu yealpha-ketoglutarate, kiyi yepakati mune citric acid cycle (inozivikanwawo seKrebs cycle). Kutenderera uku kwakakosha pakugadzirwa kweadenosine triphosphate (ATP), masero edu ekutanga simba sosi. Pamusoro pebasa rayo mukugadzira simba, alpha-ketoglutarate inoitawo basa rakakosha muamino acid metabolism.
Zvimwe zvidzidzo zvinoratidza kuti Ca-AKG inogonawo kuva nemigumisiro yakanaka pakunzwa kwe insulin. Insulin ihomoni inoita basa rakakosha mukugadzirisa mazinga eshuga yeropa uye kuchengetedza simba mumuviri. Nekutsigira insulin senitivity, Ca-AKG inogona kubatsira vanhu kubata zvirinani mazinga eshuga yeropa uye kuderedza njodzi yekurema.
Chidzidzo chemhuka chakabudiswa mujenari Aging Cell inoratidza kuti alpha-ketoglutarate inogona kuderedza uremu nekuvandudza kumwe kufutisa uye zvirwere zvinhu. Zvinonyanya kukosha zvinosanganisira:
● kuderera kwemafuta
● Kuvandudza kushivirira kweglucose
●Kuwedzera brown adipose tissue (mafuta)
4.Regulates Energy uye Metabolism
Calcium alpha-ketoglutarate inosimudzira kugadzirwa kwesimba padanho remasero. Nekutsigira kutenderera kweKrebs, Ca-AKG inobatsira kukwidziridza shanduko yezvinovaka muviri kuita ATP, masero edu ekutanga sosi yesimba.
Uyezve, calcium alpha ketoglutarate yakaratidzwa kutsigira hutano hwemetabolism. Metabolism inoreva maitiro emakemikari anochengetedza hupenyu anoitika mumiviri yedu, uye inoshanda zvakanaka metabolism yakakosha pakugadzira simba, kukura, uye kugadzirisa. Ca-AKG inobatsira kudzora metabolism nekusimudzira kushandiswa kwakanaka kwemakabhohaidhiretsi, mafuta, uye mapuroteni, masero ekutanga simba masosi.
Pamusoro pebasa rayo mukugadzira simba uye metabolic regulation, calcium alpha-ketoglutarate zvakare ine antioxidant zvimiro. Se antioxidant, Ca-AKG inobatsira kudzikamisa zvinokuvadza emahara radicals, izvo zvinogona kukuvadza maseru uye kubatsira kune akasiyana mamiriro anosanganisira oxidative kusagadzikana, kuzvimba, uye kuchembera. Nekudzikisa kukuvara kweoxidative, calcium alpha-ketoglutarate inotsigira hutano hwesero uye basa.
Chimwe chezvinhu zvakakosha zvekufunga nezvazvo pakusarudza Ca-AKG yekuwedzera kunaka kwechigadzirwa. Tarisa zvekuwedzera zvakagadzirwa nemugadziri ane mukurumbira anotevera maitiro akanaka ekugadzira (GMP) uye ari wechitatu-bato akaedzwa kuchena uye simba. Izvi zvinovimbisa kuti iwe unowana chemhando yepamusoro chigadzirwa chisina tsvina uye chinosangana nemazita ezvinyorwa.
Imwe yekufunga kwakakosha pakusarudza Ca-AKG yekuwedzera ndiyo fomu yekuwedzera. Ca-AKG inowanikwa muupfu uye capsule mafomu, imwe neimwe iine zvayakanakira nezvayakaipira. Hupfu hwekuwedzera hunowanzo kunyudzwa nyore nemuviri uye hunogona kusanganiswa muzvinwiwa kana masmoothies kuti zvishandiswe nyore. Capsules, kune rumwe rutivi, zviri nyore uye zviri nyore kutakura. Pakusarudza fomu rekuwedzera rakakunakira iwe, funga nezvemararamiro ako uye zvaunoda iwe pachako.
Pamusoro pemhando uye fomu, zvakakoshawo kufunga nezveyero uye kusungwa kweCa-AKG mukuwedzera. Tarisa zvigadzirwa zvinopa dosi rakakwana reCa-AKG kusangana nezvido zvako zvega. Izvo zvakakoshawo kuti utarise kusungirirwa kweCa-AKG mukuwedzera - kuwanda kwepamusoro kungangoda madhisi madiki, angave ari nyore kune vamwe vanhu.
Pamusoro pezvo, zvakakosha kufunga chero zvimwe zvinongedzo muCa-AKG zvinowedzera. Zvimwe zvinowedzera zvinogona kunge zvine akawedzera mafirita, mapreservatives, kana allergens zvaungade kudzivirira. Kana uine allergies kana zvirambidzo zvekudya, tsvaga ma supplements ane mashoma akawedzera zvimisikidzo uye pasina zvinojairika zvinokonzeresa.
Chekupedzisira, funga mutengo uye kukosha kweCa-AKG yekuwedzera. Kunyangwe zvingave zvichiyedza kusarudza sarudzo yakachipa, zvakakosha kufunga nezve kukosha kwese kwekuwedzera. Tsvaga chigadzirwa chinopa yemhando yepamusoro, ine simba fomula nemutengo unokwanisika. Funga nezve mutengo pasevhisi uye kukosha kwese kwekuwedzera zvichienderana nemhando yayo, chimiro, dosi, uye zvimwe zvinongedzo.
Iyo kambani Suzhou Myland Pharm & Nutrition Inc.yave ichiita bhizinesi rekuwedzera chikafu kubva 1992. Ndiyo kambani yekutanga muChina kugadzira nekutengesa mhodzi dzemazambiringa.
Iine makore makumi matatu echiitiko uye ichitungamirwa nehunyanzvi hwepamusoro uye yakagadziridzwa zvakanyanya R&D zano, kambani yakagadzira mhando yezvigadzirwa zvemakwikwi uye ikava yekuvandudza hupenyu hwesainzi yekuwedzera, yetsika synthesis uye kambani yekugadzira masevhisi.
Pamusoro pezvo, kambani iyi zvakare FDA-yakanyoreswa mugadziri, inovimbisa hutano hwevanhu nemhando yakagadzikana uye kukura kwakasimba. Zviwanikwa zvekambani zveR&D uye zvivakwa zvekugadzira uye zviridzwa zvekuongorora ndezvemazuva ano uye zvinoshanda, uye zvinokwanisa kugadzira makemikari pamilligram kusvika toni sikero zvichiteerana neISO 9001 zviyero uye GMP maitiro ekugadzira.
Mubvunzo: Chii chinonzi Calcium Alpha Ketoglutarate?
A: Calcium Alpha Ketoglutarate is a supplement inobatanidza calcium ne alpha ketoglutaric acid, iyo inobatanidza iyo inoita basa rinokosha mukugadzirwa kwesimba uye kudya kunovaka muviri mumuviri.
Mubvunzo: Ndezvipi zvakanakira kutora Calcium Alpha Ketoglutarate supplements?
A: Calcium Alpha Ketoglutarate zvinowedzera zvakaratidzwa kutsigira hutano hwemapfupa, kuwedzera kushanda kwemhasuru, kunatsiridza kutsungirira kwekurovedza muviri, uye kukurudzira hutano hwakakwana uye kugara zvakanaka.
Mubvunzo: Ko Calcium Alpha Ketoglutarate yekuwedzera inogona kubatsira vatambi uye vanofarira kusimba?
A: Hongu, Calcium Alpha Ketoglutarate supplements inogona kuvandudza kurovedza muviri uye kutsungirira nekusimudzira kugadzirwa kwesimba uye kudya kunovaka muviri mumuviri.
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Nguva yekutumira: Feb-22-2024
